iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-063019

Ensembl Protein ID

ENSMODP00000022340.2

UniProt Accession

F7F2C8; F7F2C8_MONDO

Protein Name

Uncharacterized protein

Gene Name

STRAP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000017913.3	ENSMODT00000022730.2	ENSMODP00000022340.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-27	94.2	263	294
UBD/Beta-Prp	2.00e-40	139.0	12	294

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtll.vsGsdDgtikvWDl 30
           gH ++++c++f  d+ l +sGs Dgt+++W +
   Q: 263  GHFGPIHCVRFsADGELyASGSEDGTLRLWQT 294
           799********9555665************85 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkf...spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           gh   ++ +++f   +p + +l+++++dg+  + + +tg+ + ++ gh+++v+  ++++d+   +t++ D t+kvwd  +g+ ++tl  
   Q: 12   GHTR-PVVDLAFsgiTPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLA- 98
           4444.5555888888899999*******************************************************************. PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtd 181
           h++ v s++f +++++l++G++d+ +r++dl++ +   +  sgh++ +  + +  d+   + +++D+tvrlWd +t++ ++ l    + 
   Q: 99   HKHIVKSVDFTQDSNYLLTGGQDKLLRIYDLNKSEAEPKEISGHTSGIKKALWCRDDTQ-ILSADDKTVRLWDRATMTEVKSLN--FNM 184
           **************************************9**************996654.55679*********9999999994..588 PP
   S: 182  svyslsfdsng........................................kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrf 230
           sv s+++ ++g                                        ++lv+g++d ++  +d+ +ge +++++gh  ++ +vrf
   Q: 185  SVSSMEYIPEGeilvitygrsiafhsaaslepiksfeapapinsaslhpekEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRF 273
           888888777777777777777777777777777777777777777777777************************************** PP
   S: 231  spnderlvsgssDgsiriWdl 251
           s ++e+++sgs+Dg++r+W +
   Q: 274  SADGELYASGSEDGTLRLWQT 294
           *******************65 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAMRQTPLTC SGHTRPVVDL AFSGITPYGY FLISACKDGK PMLRQGDTGD WIGTFLGHKG 60
AVWGATLNKD ATKAATAAAD FTAKVWDAVS GDELMTLAHK HIVKSVDFTQ DSNYLLTGGQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGCTCCTG CCACCGCCGC CATGGCGATG AGGCAGACTC CGCTCACCTG CTCCGGGCAC 60
ACGCGGCCTG TGGTGGATCT GGCCTTCAGT GGCATCACTC CCTATGGCTA TTTCCTAATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0032797--C:SMN complex
GO:0034719--C:SMN-Sm protein complex
GO:0003723--F:RNA binding
GO:0030277--P:maintenance of gastrointestinal epithelium
GO:0010633--P:negative regulation of epithelial cell migration
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0010719--P:negative regulation of epithelial to mesenchymal transition
GO:0060394--P:negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030512--P:negative regulation of transforming growth factor beta receptor signaling pathway
GO:0000387--P:spliceosomal snRNP assembly

KEGG

mdo:100011489

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000668	Aegilops tauschii	49.31	2.00e-74	272.00
IUUC-Aml-002091	Ailuropoda melanoleuca	92.31	0.00e+00	627.00
IUUC-Atr-002571	Amborella trichopoda	50.52	3.00e-76	278.00
IUUC-Apl-003327	Anas platyrhynchos	85.76	2.00e-146	511.00
IUUC-Aca-005324	Anolis carolinensis	88.86	2.00e-168	584.00
IUUC-Aly-006452	Arabidopsis lyrata	49.32	9.00e-76	276.00
IUUC-Ath-006646	Arabidopsis thaliana	49.32	7.00e-76	277.00
IUUC-Acl-008014	Aspergillus clavatus	40.18	1.00e-47	183.00
IUUC-Afl-008701	Aspergillus flavus	39.51	5.00e-34	138.00
IUUC-Afu-008942	Aspergillus fumigatus	30.40	5.00e-34	138.00
IUUC-Ani-009394	Aspergillus nidulans	40.95	1.00e-49	190.00
IUUC-Ang-009593	Aspergillus niger	37.63	2.00e-35	143.00
IUUC-Aor-010206	Aspergillus oryzae	41.49	3.00e-49	188.00
IUUC-Ame-011328	Astyanax mexicanus	83.07	9.00e-144	502.00
IUUC-Bgr-012308	Blumeria graminis	39.53	2.00e-56	213.00
IUUC-Bta-013429	Bos taurus	95.14	0.00e+00	630.00
IUUC-Bci-013803	Botrytis cinerea	40.64	7.00e-55	207.00
IUUC-Bdi-014996	Brachypodium distachyon	48.25	9.00e-74	270.00
IUUC-Bol-016595	Brassica oleracea	49.66	6.00e-78	284.00
IUUC-Bra-017775	Brassica rapa	48.81	8.00e-77	281.00
IUUC-Cja-018740	Callithrix jacchus	90.63	1.00e-176	612.00
IUUC-Cfa-021145	Canis familiaris	96.00	0.00e+00	633.00
IUUC-Cpo-022373	Cavia porcellus	94.86	0.00e+00	631.00
IUUC-Cre-022806	Chlamydomonas reinhardtii	43.49	9.00e-61	226.00
IUUC-Csa-023098	Chlorocebus sabaeus	94.00	4.00e-180	623.00
IUUC-Cho-024856	Choloepus hoffmanni	87.43	3.00e-158	551.00
IUUC-Cin-025541	Ciona intestinalis	58.06	9.00e-102	363.00
IUUC-Csv-026287	Ciona savignyi	57.44	1.00e-91	328.00
IUUC-Cgl-026513	Colletotrichum gloeosporioides	40.48	6.00e-53	201.00
IUUC-Cne-026869	Cryptococcus neoformans	46.54	2.00e-69	256.00
IUUC-Dre-028457	Danio rerio	76.64	2.00e-147	514.00
IUUC-Dno-029213	Dasypus novemcinctus	95.71	0.00e+00	636.00
IUUC-Dse-031350	Dothistroma septosporum	40.48	5.00e-52	197.00
IUUC-Dme-031857	Drosophila melanogaster	60.69	6.00e-107	380.00
IUUC-Ete-032558	Echinops telfairi	85.66	2.00e-118	417.00
IUUC-Eca-033934	Equus caballus	95.43	0.00e+00	632.00
IUUC-Eeu-034650	Erinaceus europaeus	82.00	1.00e-159	555.00
IUUC-Fca-035909	Felis catus	95.71	0.00e+00	631.00
IUUC-Fal-036706	Ficedula albicollis	85.99	2.00e-142	498.00
IUUC-Fox-037780	Fusarium oxysporum	40.48	2.00e-51	196.00
IUUC-Fso-038197	Fusarium solani	40.12	1.00e-52	199.00
IUUC-Gmo-039707	Gadus morhua	78.32	1.00e-133	469.00
IUUC-Ggr-040054	Gaeumannomyces graminis	39.40	5.00e-54	204.00
IUUC-Gga-040901	Gallus gallus	88.00	3.00e-172	597.00
IUUC-Gac-041876	Gasterosteus aculeatus	74.00	2.00e-141	495.00
IUUC-Gma-044014	Glycine max	49.83	3.00e-76	278.00
IUUC-Ggo-044583	Gorilla gorilla	88.32	4.00e-165	573.00
IUUC-Hsa-046553	Homo sapiens	90.91	3.00e-178	617.00
IUUC-Hvu-047544	Hordeum vulgare	49.66	5.00e-76	277.00
IUUC-Itr-047980	Ictidomys tridecemlineatus	96.00	0.00e+00	638.00
IUUC-Lch-050078	Latimeria chalumnae	83.19	6.00e-157	546.00
IUUC-Lpe-051246	Leersia perrieri	49.83	1.00e-76	279.00
IUUC-Loc-052598	Lepisosteus oculatus	78.92	7.00e-151	526.00
IUUC-Lma-053226	Leptosphaeria maculans	45.57	1.00e-55	210.00
IUUC-Laf-054053	Loxodonta africana	95.14	0.00e+00	634.00
IUUC-Mcc-054652	Macaca mulatta	90.66	2.00e-178	618.00
IUUC-Mor-057256	Magnaporthe oryzae	38.87	1.00e-52	199.00
IUUC-Mpo-057303	Magnaporthe poae	39.76	1.00e-54	206.00
IUUC-Mtr-058421	Medicago truncatula	50.17	1.00e-76	280.00
IUUC-Mla-059073	Melampsora laricipopulina	45.11	7.00e-63	234.00
IUUC-Mga-059664	Meleagris gallopavo	87.75	7.00e-171	592.00
IUUC-Mvi-060534	Microbotryum violaceum	34.04	1.00e-38	154.00
IUUC-Mmr-061044	Microcebus murinus	96.59	6.00e-176	609.00
IUUC-Mmu-064092	Mus musculus	96.00	0.00e+00	634.00
IUUC-Mac-065143	Musa acuminata	50.52	2.00e-75	275.00
IUUC-Mpu-066557	Mustela putorius furo	96.00	0.00e+00	638.00
IUUC-Mlu-068179	Myotis lucifugus	95.43	0.00e+00	631.00
IUUC-Nfi-068553	Neosartorya fischeri	40.48	2.00e-47	182.00
IUUC-Ncr-068934	Neurospora crassa	38.82	2.00e-48	186.00
IUUC-Nle-069482	Nomascus leucogenys	90.63	3.00e-177	614.00
IUUC-Opr-071055	Ochotona princeps	74.86	7.00e-129	453.00
IUUC-Ont-072663	Oreochromis niloticus	74.79	5.00e-140	490.00
IUUC-Ocu-074942	Oryctolagus cuniculus	95.43	0.00e+00	631.00
IUUC-Oba-075160	Oryza barthii	49.66	1.00e-76	279.00
IUUC-Obr-076864	Oryza brachyantha	49.83	1.00e-76	279.00
IUUC-Ogl-077076	Oryza glaberrima	49.66	2.00e-76	279.00
IUUC-Ogu-078591	Oryza glumaepatula	49.66	1.00e-76	279.00
IUUC-Oin-079631	Oryza indica	48.80	4.00e-75	274.00
IUUC-Olo-080389	Oryza longistaminata	43.19	2.00e-48	185.00
IUUC-Ome-081693	Oryza meridionalis	48.45	7.00e-74	270.00
IUUC-Oni-082190	Oryza nivara	50.00	1.00e-76	280.00
IUUC-Opu-084163	Oryza punctata	49.66	1.00e-76	280.00
IUUC-Oru-084730	Oryza rufipogon	49.66	1.00e-76	279.00
IUUC-Osa-086010	Oryza sativa	49.66	1.00e-76	280.00
IUUC-Ola-086704	Oryzias latipes	78.06	5.00e-152	530.00
IUUC-Olu-087796	Ostreococcus lucimarinus	50.51	1.00e-77	282.00
IUUC-Oga-088932	Otolemur garnettii	72.88	9.00e-125	439.00
IUUC-Oar-090398	Ovis aries	95.43	0.00e+00	631.00
IUUC-Ptr-091202	Pan troglodytes	94.29	0.00e+00	627.00
IUUC-Pan-091948	Papio anubis	94.29	0.00e+00	627.00
IUUC-Psi-093863	Pelodiscus sinensis	87.31	3.00e-152	530.00
IUUC-Pma-094255	Petromyzon marinus	79.74	1.00e-140	492.00
IUUC-Pno-095075	Phaeosphaeria nodorum	45.71	9.00e-58	216.00
IUUC-Ppa-095169	Physcomitrella patens	50.17	1.00e-79	290.00
IUUC-Pfo-096438	Poecilia formosa	77.49	3.00e-149	520.00
IUUC-Pab-097994	Pongo abelii	94.00	1.00e-180	625.00
IUUC-Pop-099172	Populus trichocarpa	49.14	1.00e-75	276.00
IUUC-Pca-100761	Procavia capensis	86.38	2.00e-152	531.00
IUUC-Ppe-102035	Prunus persica	50.34	3.00e-74	271.00
IUUC-Pva-102794	Pteropus vampyrus	87.43	4.00e-162	563.00
IUUC-Pgr-103581	Puccinia graminis	46.20	6.00e-64	237.00
IUUC-Ptt-103862	Puccinia triticina	46.28	7.00e-62	230.00
IUUC-Pte-104245	Pyrenophora teres	45.69	2.00e-58	219.00
IUUC-Pyt-104537	Pyrenophora triticirepentis	45.69	2.00e-58	219.00
IUUC-Rno-105712	Rattus norvegicus	95.71	0.00e+00	632.00
IUUC-Sha-107568	Sarcophilus harrisii	99.14	0.00e+00	657.00
IUUC-Ssl-108655	Sclerotinia sclerotiorum	39.18	1.00e-52	200.00
IUUC-Smo-108784	Selaginella moellendorffii	53.08	8.00e-82	296.00
IUUC-Sit-109807	Setaria italica	51.38	7.00e-78	284.00
IUUC-Sly-111555	Solanum lycopersicum	50.69	6.00e-76	277.00
IUUC-Stu-111953	Solanum tuberosum	50.00	3.00e-75	275.00
IUUC-Sar-113491	Sorex araneus	83.75	6.00e-115	406.00
IUUC-Sbi-114290	Sorghum bicolor	51.03	4.00e-78	284.00
IUUC-Sre-115008	Sporisorium reilianum	42.77	3.00e-63	234.00
IUUC-Ssc-116392	Sus scrofa	91.74	1.00e-178	619.00
IUUC-Tgu-116835	Taeniopygia guttata	86.03	2.00e-144	504.00
IUUC-Tru-117558	Takifugu rubripes	76.42	7.00e-149	520.00
IUUC-Tsy-119522	Tarsius syrichta	92.29	1.00e-169	588.00
IUUC-Tni-120330	Tetraodon nigroviridis	80.62	3.00e-141	494.00
IUUC-Tca-121759	Theobroma cacao	50.52	1.00e-75	276.00
IUUC-Tre-122163	Trichoderma reesei	40.60	3.00e-51	195.00
IUUC-Tvi-122609	Trichoderma virens	42.04	3.00e-52	198.00
IUUC-Tae-123053	Triticum aestivum	49.48	8.00e-76	276.00
IUUC-Tur-126808	Triticum urartu	46.12	1.00e-60	226.00
IUUC-Tme-127137	Tuber melanosporum	47.40	7.00e-68	250.00
IUUC-Tbe-127324	Tupaia belangeri	80.93	9.00e-91	326.00
IUUC-Ttr-128202	Tursiops truncatus	95.14	0.00e+00	628.00
IUUC-Uma-129433	Ustilago maydis	44.03	5.00e-62	231.00
IUUC-Vda-129675	Verticillium dahliae	38.35	3.00e-51	195.00
IUUC-Vpa-130382	Vicugna pacos	95.71	0.00e+00	633.00
IUUC-Vvi-131432	Vitis vinifera	50.86	1.00e-78	286.00
IUUC-Xtr-132648	Xenopus tropicalis	72.47	4.00e-134	470.00
IUUC-Xma-133969	Xiphophorus maculatus	74.36	3.00e-140	491.00
IUUC-Yli-134670	Yarrowia lipolytica	34.84	4.00e-44	171.00
IUUC-Zma-135878	Zea mays	51.03	3.00e-78	285.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence