iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cgl-026667

Ensembl Protein ID

ELA26359

UniProt Accession

L2FJ03; L2FJ03_COLGN

Genbank Protein ID

ELA26359.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

KB021058

Gene Name

CGGC5_1727

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CGGC5_1727	ELA26359	ELA26359

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.10e-50	170.2	303	780
UBD/Alpha-Helix/UBA	1.40e-18	66.1	646	685

Active Site

Position(s)	Description	Evidence
312	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
737	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeel............w...kskkkavsprellkalkkeaeefsg 86
           tGlkNlgN+CY+ S++QcL+ +p +++ ++    ++l+     +p ++l ++l++l++              +     ++k  +p +l++ +++ + efs+
   Q: 303  TGLKNLGNSCYLASIVQCLFDTPAFKNRYFL-PARDLPVV--HDPAEDLETQLRSLISGRysrpdsdavpsdQspdLPTQKGLAPAMLKHLIGRGHAEFST 400
           7*************************99998.78888877..689************9994444444444331444666669******************* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke.. 185
           ++qqDa E+l+++++ + ++                            +       ++ F++ l+++++cl c++v  ++++   + ++vp ++  ++e  
   Q: 401  MRQQDAFELLQHIFKLITRSP---------------------------HPPDLGDPTQPFRFVLEQRLQCLGCKKVRYSTNEQDNIFIDVPLEKLPAEEga 474
           *****************9988...........................4455566799*******************888888889999998888877799 PP
   S: 186  ..........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts........ 267
                     +l++cL++ft+ee +e    + c+ c +k   +k+  +k+lPe L+++  ++     ++++ ki+  v +p+e + l+ ++++        
   Q: 475  eakadaykpvTLRECLDNFTAEEVVE----LTCSACGSKDGYTKRSLFKTLPENLVVNARKM--AVINWVPVKIDVPVIVPDEpFLLDDYLSKglqpseet 569
           999999*******************9....9*******************************..5577*************************88888888 PP
   S: 268  ............................................................................................peekqke.. 274
                                                                                                       p     +  
   Q: 570  lpddveesapafvanpeassqleamgfgrnrcdralhatgnsdanaamewlfahmedpdideplvlsggagakgdaadpekiemlgamgfsvP-----Qak 665
           888888888888888777777777777777777777766666666666666666666666666666666666665555555555555555550.....055 PP
   S: 275  ...................................................kkkYeLiavvvHsG.slssGHYvayvknekgk...WllfdDskVtevke. 319
                                                              + kY+L ++ +H+G s++ GHYva++++e ++   W+lf+D+kV e  e 
   Q: 666  kalretsgdveravewlfshpddqgvfddeeapaaasdsaapkpeagsavtPAKYQLQSISCHKGtSIHAGHYVAFIRKEVDGhpaWVLFNDEKVVEAAEi 766
           555555555666666666666666666666666677777777777777888****************************8777799*********999653 PP
   S: 320  eevleetgstaYvlfYkr 337
           ee+     + aYv+f+kr
   Q: 767  EEMR----KFAYVYFFKR 780
           4444....58******98 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyLldg 41
           +d +k+e l +MGF+  +a++aLr++++++e+Ave+L+++
   Q: 646  ADPEKIEMLGAMGFSVPQAKKALRETSGDVERAVEWLFSH 685
           5889**********************************97 PP

Organism

Colletotrichum gloeosporioides

Protein Sequence
(Fasta)

MACPHLETIA PTLQPPTPIQ SVYREDCTQC FDSRDDPAGV DVCLQCFNGG CAGDRSHAQL 60
HRRLWEHPLV LNIRRTRKVV VRDEPPLKMS KLAIAAETEE DRFDTTTTVK CLECNQELDK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTGCC CTCATCTGGA GACCATAGCC CCAAGTTTGT GTTCCCCGAG GCTTACAGAC 60
ATCTCCCCTG CCCATGCGAA GCTTCACCCA GCTGACATCT TGCAGCTCTG CAGCCGCCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	32.02	6.00e-90	323.00
IUUC-Aml-002104	Ailuropoda melanoleuca	34.49	9.00e-124	436.00
IUUC-Atr-002580	Amborella trichopoda	34.18	8.00e-108	382.00
IUUC-Apl-003774	Anas platyrhynchos	35.38	8.00e-120	422.00
IUUC-Aca-005368	Anolis carolinensis	34.64	5.00e-125	440.00
IUUC-Aly-005727	Arabidopsis lyrata	35.01	1.00e-113	402.00
IUUC-Ath-006974	Arabidopsis thaliana	35.50	1.00e-115	408.00
IUUC-Ago-007890	Ashbya gossypii	32.18	1.00e-104	372.00
IUUC-Acl-008057	Aspergillus clavatus	55.76	0.00e+00	864.00
IUUC-Afl-008547	Aspergillus flavus	57.40	0.00e+00	778.00
IUUC-Afu-008805	Aspergillus fumigatus	53.08	0.00e+00	778.00
IUUC-Ani-009441	Aspergillus nidulans	53.25	0.00e+00	717.00
IUUC-Ang-009720	Aspergillus niger	57.58	0.00e+00	872.00
IUUC-Aor-010111	Aspergillus oryzae	58.30	0.00e+00	934.00
IUUC-Ate-010531	Aspergillus terreus	55.51	0.00e+00	819.00
IUUC-Ame-011893	Astyanax mexicanus	33.47	6.00e-99	353.00
IUUC-Bgr-012183	Blumeria graminis	61.41	0.00e+00	973.00
IUUC-Bta-013179	Bos taurus	34.30	1.00e-121	428.00
IUUC-Bci-013858	Botrytis cinerea	67.68	0.00e+00	1088.00
IUUC-Bdi-014904	Brachypodium distachyon	33.70	1.00e-96	345.00
IUUC-Bol-015296	Brassica oleracea	34.81	3.00e-113	400.00
IUUC-Bra-017619	Brassica rapa	34.57	5.00e-113	400.00
IUUC-Cel-018625	Caenorhabditis elegans	30.15	6.00e-78	283.00
IUUC-Cja-019063	Callithrix jacchus	34.10	1.00e-121	428.00
IUUC-Cfa-020976	Canis familiaris	35.06	1.00e-125	442.00
IUUC-Cpo-022265	Cavia porcellus	34.91	5.00e-125	440.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	34.93	2.00e-69	254.00
IUUC-Csa-024177	Chlorocebus sabaeus	34.85	1.00e-112	399.00
IUUC-Cho-024702	Choloepus hoffmanni	32.53	3.00e-71	261.00
IUUC-Cin-025411	Ciona intestinalis	33.70	2.00e-97	348.00
IUUC-Csv-026347	Ciona savignyi	32.06	3.00e-98	350.00
IUUC-Cne-026831	Cryptococcus neoformans	46.36	4.00e-180	623.00
IUUC-Cme-027335	Cyanidioschyzon merolae	33.92	9.00e-53	200.00
IUUC-Dre-027982	Danio rerio	31.90	3.00e-99	354.00
IUUC-Dno-029034	Dasypus novemcinctus	34.64	5.00e-124	436.00
IUUC-Dor-030479	Dipodomys ordii	33.85	7.00e-53	200.00
IUUC-Dse-031467	Dothistroma septosporum	55.65	0.00e+00	868.00
IUUC-Dme-032075	Drosophila melanogaster	33.66	3.00e-103	367.00
IUUC-Ete-032865	Echinops telfairi	31.71	2.00e-103	368.00
IUUC-Eca-034059	Equus caballus	34.29	3.00e-122	431.00
IUUC-Eeu-035304	Erinaceus europaeus	36.05	2.00e-115	408.00
IUUC-Fca-035515	Felis catus	34.18	2.00e-122	431.00
IUUC-Fal-037271	Ficedula albicollis	35.55	4.00e-117	414.00
IUUC-Fox-037745	Fusarium oxysporum	75.98	0.00e+00	1197.00
IUUC-Fso-038158	Fusarium solani	77.76	0.00e+00	1193.00
IUUC-Gmo-039071	Gadus morhua	34.16	1.00e-110	392.00
IUUC-Ggr-040098	Gaeumannomyces graminis	71.18	0.00e+00	1087.00
IUUC-Gga-040635	Gallus gallus	34.72	3.00e-124	437.00
IUUC-Gac-042528	Gasterosteus aculeatus	34.52	5.00e-114	403.00
IUUC-Gma-043614	Glycine max	33.87	6.00e-106	376.00
IUUC-Ggo-044602	Gorilla gorilla	34.19	9.00e-123	432.00
IUUC-Hsa-045959	Homo sapiens	34.19	9.00e-123	432.00
IUUC-Hvu-047563	Hordeum vulgare	37.07	1.00e-94	339.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	34.37	2.00e-123	435.00
IUUC-Kpa-049156	Komagataella pastoris	41.02	7.00e-172	595.00
IUUC-Lch-049648	Latimeria chalumnae	34.52	9.00e-118	416.00
IUUC-Lpe-051523	Leersia perrieri	31.99	6.00e-95	340.00
IUUC-Loc-052072	Lepisosteus oculatus	30.98	7.00e-101	360.00
IUUC-Lma-053216	Leptosphaeria maculans	62.85	0.00e+00	947.00
IUUC-Laf-054327	Loxodonta africana	34.30	1.00e-122	432.00
IUUC-Mcc-055443	Macaca mulatta	34.41	2.00e-123	435.00
IUUC-Meu-056298	Macropus eugenii	32.48	4.00e-78	284.00
IUUC-Mor-057106	Magnaporthe oryzae	72.69	0.00e+00	1145.00
IUUC-Mpo-057589	Magnaporthe poae	71.68	0.00e+00	1094.00
IUUC-Mtr-058680	Medicago truncatula	35.10	2.00e-109	388.00
IUUC-Mla-058903	Melampsora laricipopulina	42.65	9.00e-176	608.00
IUUC-Mga-059669	Meleagris gallopavo	35.05	4.00e-117	413.00
IUUC-Mvi-060476	Microbotryum violaceum	43.42	8.00e-171	592.00
IUUC-Mmr-060575	Microcebus murinus	34.64	4.00e-124	437.00
IUUC-Mdo-062183	Monodelphis domestica	33.92	1.00e-118	418.00
IUUC-Mmu-063592	Mus musculus	34.53	5.00e-124	436.00
IUUC-Mac-065634	Musa acuminata	32.34	7.00e-100	356.00
IUUC-Mpu-066082	Mustela putorius furo	35.42	1.00e-126	446.00
IUUC-Mlu-067345	Myotis lucifugus	34.45	2.00e-122	431.00
IUUC-Nfi-068558	Neosartorya fischeri	55.95	0.00e+00	840.00
IUUC-Ncr-068960	Neurospora crassa	70.03	0.00e+00	1069.00
IUUC-Nle-070173	Nomascus leucogenys	34.72	5.00e-124	436.00
IUUC-Opr-070556	Ochotona princeps	34.87	3.00e-124	437.00
IUUC-Ont-071502	Oreochromis niloticus	34.05	2.00e-112	398.00
IUUC-Oan-072959	Ornithorhynchus anatinus	39.30	4.00e-42	162.00
IUUC-Ocu-074861	Oryctolagus cuniculus	35.06	5.00e-125	440.00
IUUC-Oba-075109	Oryza barthii	32.75	2.00e-97	348.00
IUUC-Obr-076292	Oryza brachyantha	32.59	7.00e-95	340.00
IUUC-Ogl-077065	Oryza glaberrima	34.12	1.00e-105	375.00
IUUC-Ogu-078776	Oryza glumaepatula	32.63	2.00e-101	362.00
IUUC-Oin-080048	Oryza indica	33.70	1.00e-104	372.00
IUUC-Olo-080711	Oryza longistaminata	32.53	3.00e-92	331.00
IUUC-Ome-081506	Oryza meridionalis	33.25	2.00e-93	335.00
IUUC-Oni-082320	Oryza nivara	31.48	7.00e-95	340.00
IUUC-Opu-083801	Oryza punctata	32.51	1.00e-91	329.00
IUUC-Oru-085139	Oryza rufipogon	31.72	4.00e-95	340.00
IUUC-Osa-085713	Oryza sativa	33.95	3.00e-106	377.00
IUUC-Ola-086951	Oryzias latipes	33.53	5.00e-105	373.00
IUUC-Olu-087822	Ostreococcus lucimarinus	31.80	6.00e-92	330.00
IUUC-Oga-088625	Otolemur garnettii	34.18	6.00e-123	433.00
IUUC-Oar-089995	Ovis aries	34.37	7.00e-123	432.00
IUUC-Ptr-090640	Pan troglodytes	34.87	6.00e-125	439.00
IUUC-Pan-091974	Papio anubis	34.33	8.00e-124	436.00
IUUC-Psi-093957	Pelodiscus sinensis	34.88	2.00e-127	448.00
IUUC-Pma-094242	Petromyzon marinus	38.70	5.00e-64	236.00
IUUC-Pno-094835	Phaeosphaeria nodorum	62.02	0.00e+00	868.00
IUUC-Ppa-095901	Physcomitrella patens	35.79	3.00e-114	404.00
IUUC-Pfo-097148	Poecilia formosa	34.56	4.00e-112	397.00
IUUC-Pab-098068	Pongo abelii	31.78	1.00e-103	369.00
IUUC-Pop-098855	Populus trichocarpa	33.70	9.00e-105	372.00
IUUC-Pca-100738	Procavia capensis	35.61	9.00e-89	319.00
IUUC-Ppe-101315	Prunus persica	32.92	1.00e-101	362.00
IUUC-Pva-102154	Pteropus vampyrus	34.18	7.00e-121	426.00
IUUC-Pgr-103343	Puccinia graminis	42.35	7.00e-146	509.00
IUUC-Ptt-103928	Puccinia triticina	37.18	4.00e-139	487.00
IUUC-Pte-104306	Pyrenophora teres	63.13	0.00e+00	919.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	62.56	0.00e+00	941.00
IUUC-Rno-105801	Rattus norvegicus	34.42	2.00e-123	435.00
IUUC-Sce-106304	Saccharomyces cerevisiae	34.03	2.00e-114	405.00
IUUC-Sha-107635	Sarcophilus harrisii	34.04	1.00e-119	422.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	42.97	2.00e-172	597.00
IUUC-Spo-108144	Schizosaccharomyces pombe	42.73	2.00e-173	600.00
IUUC-Smo-108703	Selaginella moellendorffii	36.50	8.00e-111	392.00
IUUC-Sit-110728	Setaria italica	33.13	3.00e-108	384.00
IUUC-Sly-111523	Solanum lycopersicum	35.15	5.00e-117	413.00
IUUC-Sar-113733	Sorex araneus	37.42	5.00e-51	194.00
IUUC-Sbi-114419	Sorghum bicolor	33.62	4.00e-106	377.00
IUUC-Sre-115225	Sporisorium reilianum	45.34	2.00e-178	617.00
IUUC-Ssc-115686	Sus scrofa	34.49	1.00e-123	435.00
IUUC-Tgu-117346	Taeniopygia guttata	34.72	2.00e-119	421.00
IUUC-Tru-118350	Takifugu rubripes	32.60	2.00e-108	385.00
IUUC-Tsy-119278	Tarsius syrichta	31.30	4.00e-83	300.00
IUUC-Tni-120658	Tetraodon nigroviridis	32.87	2.00e-102	365.00
IUUC-Tca-121585	Theobroma cacao	33.95	3.00e-104	370.00
IUUC-Tre-122043	Trichoderma reesei	75.10	0.00e+00	1151.00
IUUC-Tvi-122303	Trichoderma virens	73.35	0.00e+00	1142.00
IUUC-Tae-125848	Triticum aestivum	34.24	2.00e-104	372.00
IUUC-Tur-126732	Triticum urartu	32.09	1.00e-92	332.00
IUUC-Tme-126909	Tuber melanosporum	60.85	0.00e+00	923.00
IUUC-Tbe-127261	Tupaia belangeri	31.72	2.00e-69	255.00
IUUC-Ttr-129119	Tursiops truncatus	35.22	2.00e-57	215.00
IUUC-Uma-129599	Ustilago maydis	44.12	0.00e+00	645.00
IUUC-Vda-129688	Verticillium dahliae	79.49	0.00e+00	1210.00
IUUC-Vpa-130170	Vicugna pacos	37.04	4.00e-41	161.00
IUUC-Vvi-131116	Vitis vinifera	34.35	2.00e-107	382.00
IUUC-Xtr-131953	Xenopus tropicalis	33.45	4.00e-111	394.00
IUUC-Xma-133837	Xiphophorus maculatus	34.56	2.00e-112	398.00
IUUC-Yli-134510	Yarrowia lipolytica	45.18	1.00e-169	588.00
IUUC-Zma-135786	Zea mays	33.83	2.00e-99	354.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence