iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gma-043614

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

CM000845

Gene Name

GLYMA_12G146600

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GLYMA12G22240	GLYMA12G22240.1	GLYMA12G22240.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.10e-53	183.4	313	806
UBD/Alpha-Helix/UBA	2.70e-16	60.7	623	663

Active Site

Position(s)	Description	Evidence
322	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
769	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelre.lllekkkeklneenpkepkgellkslqklfeel......................wkskkkavspr 71
           tGl N+gN+CYm +++Q+ ++++++++ ++l++  +k  e +p +p+ +l ++l+kl + +                      ++ k++ + p+
   Q: 313  TGLVNIGNSCYMAATMQVVFSTRSFTSrYYLNQSLKKAFEMSPADPTVDLNMQLTKLAHGIlsgkysvpafendekenvatstTTAKQEGIRPH 406
           7************************8625666677777777889*****************9999999999999888887664488888***** PP
   S: 72   ellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssr 165
           ++++++++ ++efs+ +qqDa Ef+ ++ldq+e++                              k +   s+ F++ ++++i c +  +v+  
   Q: 407  MFKSVIAASHPEFSSPRQQDALEFFLHFLDQVERAN---------------------------AGKVELDPSTSFKFGIEDRILCSSG-KVTYN 472
           *********************************988...........................45667778999***********765.55555 PP
   S: 166  eepfldlslpvpgkeetkke.............................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevL 230
           +   + lsl++p +e t+ke                              l+ cL++f+++ee+++   +y++  k k++a k+ +l+++P++L
   Q: 473  RRHDYILSLNIPLHEATNKEelesfhklkaeklaegkeinaneivrprvPLETCLANFSAPEEIHD---FYSTALKTKTTALKTAGLTSFPDYL 563
           5566778888887777777778******************************************97...************************* PP
   S: 231  ilhLkRfsfseeqksrekinkkvefpleLdlspfcts.....peekqke............................................. 274
           +lh+ Rf + e+ ++++k++ ++++p+ +d+s++ ++     +     e                                             
   Q: 564  VLHMRRF-VMEADWVPKKLDVYIDVPDIIDISHMRSKgqqsgE-----Ellpdgvpeeedsnkisandeivaqlvsmgfnhlhcqkaaintsnv 651
           *******.66778*******************99999555550.....3555555555555566677777777777777777777777777777 PP
   S: 275  .............................................................................................. 274
                                                                                                         
   Q: 652  gveeamnwllshmddpdidnpiskghgsetvdqskvdilisfgfeeeiarkalkasdgdiekatdwifnnldasvssmnaapstsasttndvnl 745
           7777777777777777777777777777778888888888888888888888888888888888888888888889999999999999999999 PP
   S: 275  ...kkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
                kY+L+++v+HsG s+++GHYva++ + +g+W  f+D+kV ++   +  +   + +Y++f++r
   Q: 746  pdgGGKYRLMGIVSHSGtSTQCGHYVAHILK-DGRWAIFNDNKVGAS--IDPPK---EMGYLYFFER 806
           999****************************.9***********998..46666...7899999886 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           ++ ++++qlv+MGF+  ++++a  ++ n  +e+A+++Ll++
   Q: 623  ANDEIVAQLVSMGFNHLHCQKAAINTsNVGVEEAMNWLLSH 663
           6899***********************************97 PP

Organism

Glycine max

Protein Sequence
(Fasta)

MTIQPLDLLR SNLSRVRIPE PTNRIYKHEC CVSFDSPRSE GGLFVDMCTF LAFGKDFVGW 60
NYEKTGNPVY LHIKQTNKLV PEDRPSKKPT LLAIGVDGGF DNNEPEYEET HSVVILPEYV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTAAAATC CCTTTCCAAT GACAGCAATA TAAAGAAGCA CACTCAATCG AAGCAAAGCA 60
CCTAGTGAAA GTGAGACTCG TTTGTATCGT ACCAAGACTT GTAAAAGACT TCATTTCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

gmx:100805602

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	63.27	0.00e+00	1003.00
IUUC-Aml-002104	Ailuropoda melanoleuca	46.14	0.00e+00	726.00
IUUC-Atr-002580	Amborella trichopoda	67.37	0.00e+00	1170.00
IUUC-Apl-003774	Anas platyrhynchos	47.03	0.00e+00	725.00
IUUC-Aca-005368	Anolis carolinensis	47.96	0.00e+00	769.00
IUUC-Aly-005727	Arabidopsis lyrata	76.49	0.00e+00	1242.00
IUUC-Ath-006974	Arabidopsis thaliana	76.00	0.00e+00	1237.00
IUUC-Ago-007890	Ashbya gossypii	28.69	7.00e-69	255.00
IUUC-Acl-008057	Aspergillus clavatus	34.51	2.00e-118	420.00
IUUC-Afu-008805	Aspergillus fumigatus	33.29	3.00e-104	372.00
IUUC-Ani-009441	Aspergillus nidulans	34.46	4.00e-97	348.00
IUUC-Ang-009720	Aspergillus niger	34.61	6.00e-112	398.00
IUUC-Ate-010531	Aspergillus terreus	32.14	4.00e-98	352.00
IUUC-Ame-011470	Astyanax mexicanus	41.33	0.00e+00	659.00
IUUC-Bgr-012183	Blumeria graminis	32.03	6.00e-104	371.00
IUUC-Bta-013179	Bos taurus	45.90	0.00e+00	731.00
IUUC-Bci-013858	Botrytis cinerea	33.58	2.00e-118	420.00
IUUC-Bdi-014904	Brachypodium distachyon	68.44	0.00e+00	1114.00
IUUC-Bol-015536	Brassica oleracea	76.02	0.00e+00	1244.00
IUUC-Bra-017939	Brassica rapa	76.46	0.00e+00	1251.00
IUUC-Cel-018625	Caenorhabditis elegans	33.54	3.00e-116	412.00
IUUC-Cja-019063	Callithrix jacchus	45.68	0.00e+00	723.00
IUUC-Cfa-020976	Canis familiaris	47.65	0.00e+00	741.00
IUUC-Cpo-022265	Cavia porcellus	47.42	0.00e+00	742.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	39.43	2.00e-115	409.00
IUUC-Csa-024078	Chlorocebus sabaeus	42.45	0.00e+00	662.00
IUUC-Cho-024702	Choloepus hoffmanni	40.73	2.00e-113	402.00
IUUC-Cin-025411	Ciona intestinalis	40.86	2.00e-173	602.00
IUUC-Csv-026347	Ciona savignyi	40.96	7.00e-170	590.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	33.70	3.00e-104	372.00
IUUC-Cne-026831	Cryptococcus neoformans	34.80	7.00e-116	411.00
IUUC-Dre-027982	Danio rerio	42.96	0.00e+00	645.00
IUUC-Dno-029034	Dasypus novemcinctus	46.37	0.00e+00	733.00
IUUC-Dor-030130	Dipodomys ordii	41.74	2.00e-96	347.00
IUUC-Dse-031467	Dothistroma septosporum	34.22	6.00e-113	402.00
IUUC-Dme-032075	Drosophila melanogaster	43.40	0.00e+00	663.00
IUUC-Ete-032865	Echinops telfairi	43.16	0.00e+00	652.00
IUUC-Eca-034059	Equus caballus	46.27	0.00e+00	729.00
IUUC-Eeu-035304	Erinaceus europaeus	44.15	0.00e+00	654.00
IUUC-Fca-035515	Felis catus	46.25	0.00e+00	731.00
IUUC-Fal-037271	Ficedula albicollis	48.31	0.00e+00	715.00
IUUC-Fox-037745	Fusarium oxysporum	34.87	6.00e-116	411.00
IUUC-Fso-038158	Fusarium solani	33.83	2.00e-111	396.00
IUUC-Gmo-039071	Gadus morhua	43.15	0.00e+00	655.00
IUUC-Ggr-040098	Gaeumannomyces graminis	33.70	3.00e-108	385.00
IUUC-Gga-040635	Gallus gallus	46.74	0.00e+00	758.00
IUUC-Gac-042528	Gasterosteus aculeatus	43.53	0.00e+00	667.00
IUUC-Ggo-044602	Gorilla gorilla	46.14	0.00e+00	730.00
IUUC-Hsa-045959	Homo sapiens	46.14	0.00e+00	730.00
IUUC-Hvu-047563	Hordeum vulgare	66.15	0.00e+00	862.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	46.02	0.00e+00	734.00
IUUC-Kpa-049156	Komagataella pastoris	30.27	2.00e-104	373.00
IUUC-Lch-049648	Latimeria chalumnae	46.45	0.00e+00	733.00
IUUC-Lpe-051523	Leersia perrieri	66.63	0.00e+00	1117.00
IUUC-Loc-052072	Lepisosteus oculatus	41.93	0.00e+00	667.00
IUUC-Lma-053216	Leptosphaeria maculans	33.42	3.00e-103	370.00
IUUC-Laf-054327	Loxodonta africana	46.25	0.00e+00	736.00
IUUC-Mcc-055443	Macaca mulatta	46.25	0.00e+00	733.00
IUUC-Meu-056298	Macropus eugenii	48.63	2.00e-151	530.00
IUUC-Mor-057106	Magnaporthe oryzae	33.94	5.00e-114	405.00
IUUC-Mpo-057589	Magnaporthe poae	33.37	7.00e-109	388.00
IUUC-Mtr-058680	Medicago truncatula	81.55	0.00e+00	1360.00
IUUC-Mla-058903	Melampsora laricipopulina	34.14	6.00e-108	385.00
IUUC-Mga-059669	Meleagris gallopavo	46.39	0.00e+00	717.00
IUUC-Mvi-060476	Microbotryum violaceum	32.54	3.00e-98	352.00
IUUC-Mmr-060575	Microcebus murinus	46.37	0.00e+00	731.00
IUUC-Mdo-062183	Monodelphis domestica	46.48	0.00e+00	736.00
IUUC-Mmu-063592	Mus musculus	46.37	0.00e+00	736.00
IUUC-Mac-065446	Musa acuminata	67.41	0.00e+00	1151.00
IUUC-Mpu-066082	Mustela putorius furo	47.65	0.00e+00	741.00
IUUC-Mlu-067345	Myotis lucifugus	45.79	0.00e+00	727.00
IUUC-Nfi-068558	Neosartorya fischeri	33.68	4.00e-114	405.00
IUUC-Ncr-068960	Neurospora crassa	32.01	5.00e-101	362.00
IUUC-Nle-070173	Nomascus leucogenys	47.41	0.00e+00	737.00
IUUC-Opr-070556	Ochotona princeps	46.49	0.00e+00	744.00
IUUC-Ont-071502	Oreochromis niloticus	44.88	0.00e+00	673.00
IUUC-Oan-072959	Ornithorhynchus anatinus	52.81	2.00e-70	258.00
IUUC-Ocu-074861	Oryctolagus cuniculus	47.65	0.00e+00	747.00
IUUC-Oba-075109	Oryza barthii	66.50	0.00e+00	1108.00
IUUC-Obr-076292	Oryza brachyantha	68.60	0.00e+00	1103.00
IUUC-Ogl-077065	Oryza glaberrima	68.11	0.00e+00	1148.00
IUUC-Ogu-078776	Oryza glumaepatula	65.88	0.00e+00	1119.00
IUUC-Oin-080048	Oryza indica	67.37	0.00e+00	1134.00
IUUC-Olo-080711	Oryza longistaminata	64.33	0.00e+00	1022.00
IUUC-Ome-081506	Oryza meridionalis	65.62	0.00e+00	1031.00
IUUC-Oni-082320	Oryza nivara	64.66	0.00e+00	1097.00
IUUC-Opu-083801	Oryza punctata	67.00	0.00e+00	1084.00
IUUC-Oru-085139	Oryza rufipogon	64.78	0.00e+00	1098.00
IUUC-Osa-085713	Oryza sativa	68.23	0.00e+00	1152.00
IUUC-Ola-086951	Oryzias latipes	42.34	0.00e+00	644.00
IUUC-Olu-087822	Ostreococcus lucimarinus	39.04	1.00e-157	550.00
IUUC-Oga-088625	Otolemur garnettii	46.07	0.00e+00	734.00
IUUC-Oar-089995	Ovis aries	45.38	0.00e+00	723.00
IUUC-Ptr-090640	Pan troglodytes	45.20	0.00e+00	728.00
IUUC-Pan-091974	Papio anubis	45.79	0.00e+00	728.00
IUUC-Psi-093957	Pelodiscus sinensis	46.74	0.00e+00	770.00
IUUC-Pma-094242	Petromyzon marinus	47.83	2.00e-104	372.00
IUUC-Pno-094835	Phaeosphaeria nodorum	35.73	1.00e-101	364.00
IUUC-Ppa-095901	Physcomitrella patens	63.57	0.00e+00	1081.00
IUUC-Pfo-097148	Poecilia formosa	44.17	0.00e+00	671.00
IUUC-Pab-098068	Pongo abelii	41.64	8.00e-174	603.00
IUUC-Pop-098855	Populus trichocarpa	82.01	0.00e+00	1285.00
IUUC-Pca-100738	Procavia capensis	43.82	3.00e-141	496.00
IUUC-Ppe-101315	Prunus persica	80.67	0.00e+00	1327.00
IUUC-Pva-102154	Pteropus vampyrus	45.90	0.00e+00	724.00
IUUC-Pgr-103343	Puccinia graminis	33.43	7.00e-101	361.00
IUUC-Ptt-103928	Puccinia triticina	29.27	5.00e-93	335.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	34.14	6.00e-103	368.00
IUUC-Rno-105801	Rattus norvegicus	46.49	0.00e+00	738.00
IUUC-Sce-106304	Saccharomyces cerevisiae	30.17	1.00e-68	254.00
IUUC-Sha-107635	Sarcophilus harrisii	47.35	0.00e+00	733.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	32.84	1.00e-98	354.00
IUUC-Smo-108848	Selaginella moellendorffii	59.25	0.00e+00	951.00
IUUC-Sit-110728	Setaria italica	69.02	0.00e+00	1170.00
IUUC-Sly-111523	Solanum lycopersicum	75.34	0.00e+00	1274.00
IUUC-Sar-113733	Sorex araneus	45.26	6.00e-96	345.00
IUUC-Sbi-114419	Sorghum bicolor	68.85	0.00e+00	1162.00
IUUC-Sre-115225	Sporisorium reilianum	32.61	5.00e-106	379.00
IUUC-Ssc-115686	Sus scrofa	45.20	0.00e+00	729.00
IUUC-Tgu-117346	Taeniopygia guttata	46.80	0.00e+00	743.00
IUUC-Tru-118350	Takifugu rubripes	42.94	0.00e+00	656.00
IUUC-Tsy-119278	Tarsius syrichta	38.57	1.00e-159	556.00
IUUC-Tni-120658	Tetraodon nigroviridis	42.84	0.00e+00	639.00
IUUC-Tca-121585	Theobroma cacao	80.00	0.00e+00	1281.00
IUUC-Tre-122043	Trichoderma reesei	34.19	5.00e-110	392.00
IUUC-Tvi-122303	Trichoderma virens	34.38	3.00e-114	405.00
IUUC-Tae-123798	Triticum aestivum	67.33	0.00e+00	1119.00
IUUC-Tur-126732	Triticum urartu	63.61	0.00e+00	1055.00
IUUC-Tme-126909	Tuber melanosporum	33.17	1.00e-98	354.00
IUUC-Tbe-127261	Tupaia belangeri	39.21	5.00e-115	408.00
IUUC-Ttr-128295	Tursiops truncatus	37.51	2.00e-158	553.00
IUUC-Uma-129599	Ustilago maydis	34.24	3.00e-115	409.00
IUUC-Vda-129688	Verticillium dahliae	33.62	6.00e-108	385.00
IUUC-Vpa-130170	Vicugna pacos	36.93	2.00e-143	502.00
IUUC-Vvi-131116	Vitis vinifera	80.37	0.00e+00	1268.00
IUUC-Xtr-131953	Xenopus tropicalis	44.82	0.00e+00	710.00
IUUC-Xma-133837	Xiphophorus maculatus	44.29	0.00e+00	674.00
IUUC-Yli-134510	Yarrowia lipolytica	33.99	5.00e-107	382.00
IUUC-Zma-135786	Zea mays	68.44	0.00e+00	1120.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence