iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pop-098943

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

CM000347

Gene Name

POPTR_0011s12760g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
POPTR_0011s12760	POPTR_0011s12760.1	POPTR_0011s12760.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.50e-53	182.1	308	797
UBD/Alpha-Helix/UBA	3.30e-16	59.9	672	710

Active Site

Position(s)	Description	Evidence
317	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
760	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkekln.eenpkepkgellkslqklfeel................wkskkkavsprell 74
           tGl NlgN+CYm +++Q+ ++++++ + + ++++ k++ e +p +p+ +l ++l+kl + +                +++k++ + pr+++
   Q: 308  TGLANLGNSCYMAATMQVVFSTRSFNSRYYTNQSLKMAfEMAPADPTVDLNMQLTKLAHGMlsgkysvpapenaaisTTNKQEGIPPRMFK 398
           7************************99988855555551456789999*************8888888888887765599999******** PP
   S: 75   kalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs.s 164
           +++++ ++efs+++qqDa Ef+ ++ldq+e+                               ++    s+ F++ ++++i c++ +    +
   Q: 399  AVIAASHPEFSSMRQQDALEFFLHFLDQVERVN---------------------------GGSSALDPSRSFKFGIEERILCPSGKVGFnK 462
           *****************************9977...........................45566667899***********987766545 PP
   S: 165  reepfldlslpvpgkeetkke.............................slqdcLesftkeeelegenkyycekckkkqeaekklklkkl 226
           r +  l+l++p+++ +  +ke                              l  cL++++++ee+++   yy++  k+k++a k+ +l+++
   Q: 463  RLDYILSLNIPLHEAT--NKEeleafhklkaekisegkdvshdeivrprvPLAACLANYSAPEEIQD---YYSTALKAKTTALKTAGLTSF 548
           5555555555555555..455569*****************************************97...********************* PP
   S: 227  PevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts.................................................. 267
           P++L+lh+ +f + ee+++++k++ ++++p+ +d+s + ++                                                  
   Q: 549  PDYLVLHMRKF-VLEEGWVPKKLDVYIDVPDIIDISYMRSKglqpgeellpdgvpeaevesnnpvanedivaqlvsmgfnhlhcqkaaint 638
           ***********.67889*******************6666688888888888888888887777777777777777777777777777777 PP
   S: 268  .....................................peekqke............................................... 274
                                                +     +                                               
   Q: 639  sntgveeamnwllahmddpdidvpvsqgahgnevdqsK-----Vdtllsfgfqeeiarkalkasggdiekatdwifnnpdasvssdmdtst 724
           66666666666666666666666666666665555550.....055555555555555555566666666666666666666666677777 PP
   S: 275  ...............kkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
                          + +Y+L+++v+H+G s+++GHYva+v + +g+W+ f+D+kV ++   +  +   + +Y++f++r
   Q: 725  ssskptpddtelpdgRGRYRLFGIVSHMGtSTHCGHYVAHVLK-DGRWVIFNDNKVAAS--INPPK---DMGYLYFFER 797
           777788888889999****************************.9***********988..34555...7888888876 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyLld 40
            d++k++ l + GF +e a++aL a+++++e A++++++
   Q: 672  VDQSKVDTLLSFGFQEEIARKALKASGGDIEKATDWIFN 710
           589**********************************97 PP

Organism

Populus trichocarpa

Protein Sequence
(Fasta)

MDLLRSNLSR VRIPEPTNRI YKHECCVSFE TPRSEGGLFV DMTTFLAFGK DYVDWNYEKT 60
GNPVYLHIKQ TRKVVPEDRP SKKPTLLAIG VEGGFDNNEP QYEETHNIVI LPDYVTFPFP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTGCTGCTC ACTTCTCATT TCTCTCTCAC AAAATCAGAA TCAAATCAAC TCTAGACCTT 60
GCATTTTCTT AGGGCAAAGC ACAAATTCCC CTCTTTTCTC TCCTCCTCCT CCTCCTCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

pop:POPTR_0011s12760g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	65.46	0.00e+00	1030.00
IUUC-Aml-002104	Ailuropoda melanoleuca	47.08	0.00e+00	741.00
IUUC-Apl-003774	Anas platyrhynchos	47.27	0.00e+00	730.00
IUUC-Aca-005368	Anolis carolinensis	48.19	0.00e+00	772.00
IUUC-Ath-006974	Arabidopsis thaliana	78.12	0.00e+00	1288.00
IUUC-Ago-007890	Ashbya gossypii	27.88	8.00e-71	261.00
IUUC-Acl-008057	Aspergillus clavatus	35.47	4.00e-121	428.00
IUUC-Afl-008547	Aspergillus flavus	35.80	4.00e-111	395.00
IUUC-Afu-008805	Aspergillus fumigatus	33.77	1.00e-106	380.00
IUUC-Ang-009720	Aspergillus niger	34.56	2.00e-111	395.00
IUUC-Aor-010111	Aspergillus oryzae	34.19	5.00e-123	434.00
IUUC-Ame-011470	Astyanax mexicanus	41.93	0.00e+00	665.00
IUUC-Bgr-012183	Blumeria graminis	31.42	2.00e-103	369.00
IUUC-Bta-013179	Bos taurus	47.31	0.00e+00	749.00
IUUC-Bdi-014904	Brachypodium distachyon	72.05	0.00e+00	1155.00
IUUC-Bol-015536	Brassica oleracea	77.56	0.00e+00	1274.00
IUUC-Cel-018625	Caenorhabditis elegans	33.87	3.00e-116	412.00
IUUC-Cja-019063	Callithrix jacchus	46.73	0.00e+00	740.00
IUUC-Cfa-020976	Canis familiaris	48.50	0.00e+00	759.00
IUUC-Cpo-022265	Cavia porcellus	48.38	0.00e+00	762.00
IUUC-Csa-024078	Chlorocebus sabaeus	43.06	0.00e+00	675.00
IUUC-Cin-025411	Ciona intestinalis	43.26	2.00e-179	622.00
IUUC-Csv-026347	Ciona savignyi	41.42	2.00e-172	599.00
IUUC-Cne-026831	Cryptococcus neoformans	34.51	3.00e-116	412.00
IUUC-Dre-027982	Danio rerio	45.39	0.00e+00	664.00
IUUC-Dno-029034	Dasypus novemcinctus	47.31	0.00e+00	747.00
IUUC-Dor-030130	Dipodomys ordii	38.05	5.00e-108	385.00
IUUC-Dse-031467	Dothistroma septosporum	35.10	2.00e-113	403.00
IUUC-Dme-032075	Drosophila melanogaster	43.54	0.00e+00	652.00
IUUC-Ete-032865	Echinops telfairi	44.09	0.00e+00	665.00
IUUC-Eca-034059	Equus caballus	46.97	0.00e+00	738.00
IUUC-Eeu-035304	Erinaceus europaeus	44.85	0.00e+00	667.00
IUUC-Fca-035515	Felis catus	47.42	0.00e+00	750.00
IUUC-Fal-037271	Ficedula albicollis	49.06	0.00e+00	726.00
IUUC-Fox-037745	Fusarium oxysporum	35.44	6.00e-121	427.00
IUUC-Fso-038158	Fusarium solani	35.02	7.00e-116	410.00
IUUC-Gmo-039071	Gadus morhua	44.79	0.00e+00	670.00
IUUC-Gga-040635	Gallus gallus	47.31	0.00e+00	766.00
IUUC-Gac-042528	Gasterosteus aculeatus	44.93	0.00e+00	681.00
IUUC-Ggo-044602	Gorilla gorilla	47.19	0.00e+00	748.00
IUUC-Hsa-045959	Homo sapiens	47.19	0.00e+00	748.00
IUUC-Hvu-047563	Hordeum vulgare	69.16	0.00e+00	892.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	47.07	0.00e+00	751.00
IUUC-Kpa-049156	Komagataella pastoris	31.08	6.00e-103	368.00
IUUC-Lch-049648	Latimeria chalumnae	48.01	0.00e+00	751.00
IUUC-Lpe-051523	Leersia perrieri	69.98	0.00e+00	1147.00
IUUC-Loc-052072	Lepisosteus oculatus	42.42	0.00e+00	676.00
IUUC-Laf-054327	Loxodonta africana	47.19	0.00e+00	746.00
IUUC-Mcc-055443	Macaca mulatta	47.31	0.00e+00	749.00
IUUC-Meu-056298	Macropus eugenii	49.66	3.00e-154	538.00
IUUC-Mla-058903	Melampsora laricipopulina	33.46	8.00e-105	374.00
IUUC-Mga-059669	Meleagris gallopavo	47.23	0.00e+00	725.00
IUUC-Mmr-060575	Microcebus murinus	47.31	0.00e+00	746.00
IUUC-Mdo-062183	Monodelphis domestica	47.62	0.00e+00	754.00
IUUC-Mmu-063592	Mus musculus	47.42	0.00e+00	747.00
IUUC-Mpu-066082	Mustela putorius furo	48.38	0.00e+00	759.00
IUUC-Mlu-067345	Myotis lucifugus	46.73	0.00e+00	742.00
IUUC-Nfi-068558	Neosartorya fischeri	34.94	2.00e-116	412.00
IUUC-Ncr-068960	Neurospora crassa	31.25	6.00e-101	361.00
IUUC-Nle-070173	Nomascus leucogenys	48.38	0.00e+00	758.00
IUUC-Opr-070556	Ochotona princeps	47.54	0.00e+00	761.00
IUUC-Ont-071502	Oreochromis niloticus	46.48	0.00e+00	691.00
IUUC-Oan-072959	Ornithorhynchus anatinus	52.34	3.00e-69	254.00
IUUC-Ocu-074861	Oryctolagus cuniculus	48.62	0.00e+00	769.00
IUUC-Oba-075109	Oryza barthii	70.65	0.00e+00	1148.00
IUUC-Obr-076292	Oryza brachyantha	71.77	0.00e+00	1138.00
IUUC-Ogl-077065	Oryza glaberrima	72.26	0.00e+00	1189.00
IUUC-Ogu-078776	Oryza glumaepatula	70.52	0.00e+00	1167.00
IUUC-Oin-080048	Oryza indica	71.89	0.00e+00	1182.00
IUUC-Olo-080711	Oryza longistaminata	68.85	0.00e+00	1068.00
IUUC-Ome-081506	Oryza meridionalis	70.25	0.00e+00	1077.00
IUUC-Oni-082320	Oryza nivara	68.92	0.00e+00	1140.00
IUUC-Opu-083801	Oryza punctata	71.27	0.00e+00	1130.00
IUUC-Oru-085139	Oryza rufipogon	68.56	0.00e+00	1134.00
IUUC-Osa-085713	Oryza sativa	72.39	0.00e+00	1192.00
IUUC-Ola-086951	Oryzias latipes	43.95	0.00e+00	659.00
IUUC-Olu-087822	Ostreococcus lucimarinus	39.69	2.00e-161	562.00
IUUC-Oga-088625	Otolemur garnettii	46.78	0.00e+00	747.00
IUUC-Oar-089995	Ovis aries	46.78	0.00e+00	741.00
IUUC-Ptr-090640	Pan troglodytes	46.37	0.00e+00	745.00
IUUC-Pan-091974	Papio anubis	46.73	0.00e+00	743.00
IUUC-Psi-093957	Pelodiscus sinensis	46.97	0.00e+00	773.00
IUUC-Ppa-095901	Physcomitrella patens	65.09	0.00e+00	1089.00
IUUC-Pfo-097148	Poecilia formosa	45.64	0.00e+00	684.00
IUUC-Pab-098672	Pongo abelii	40.64	2.00e-176	612.00
IUUC-Pva-102154	Pteropus vampyrus	46.95	0.00e+00	742.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	33.73	4.00e-101	362.00
IUUC-Rno-105801	Rattus norvegicus	47.42	0.00e+00	748.00
IUUC-Sce-106304	Saccharomyces cerevisiae	31.07	6.00e-67	248.00
IUUC-Sha-107635	Sarcophilus harrisii	47.95	0.00e+00	752.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	31.25	2.00e-91	329.00
IUUC-Spo-108144	Schizosaccharomyces pombe	33.86	3.00e-110	392.00
IUUC-Smo-108848	Selaginella moellendorffii	62.72	0.00e+00	989.00
IUUC-Sit-110728	Setaria italica	73.13	0.00e+00	1212.00
IUUC-Sar-113733	Sorex araneus	45.50	1.00e-95	343.00
IUUC-Sbi-114419	Sorghum bicolor	73.10	0.00e+00	1200.00
IUUC-Sre-115225	Sporisorium reilianum	32.46	7.00e-104	371.00
IUUC-Ssc-115686	Sus scrofa	46.72	0.00e+00	745.00
IUUC-Tgu-117346	Taeniopygia guttata	47.37	0.00e+00	749.00
IUUC-Tru-118350	Takifugu rubripes	44.95	0.00e+00	674.00
IUUC-Tsy-119278	Tarsius syrichta	39.34	7.00e-163	566.00
IUUC-Tni-120658	Tetraodon nigroviridis	44.86	0.00e+00	659.00
IUUC-Tca-121585	Theobroma cacao	84.39	0.00e+00	1321.00
IUUC-Tre-122043	Trichoderma reesei	33.58	4.00e-111	395.00
IUUC-Tvi-122303	Trichoderma virens	33.91	2.00e-113	402.00
IUUC-Tae-123798	Triticum aestivum	70.19	0.00e+00	1154.00
IUUC-Tur-126732	Triticum urartu	65.47	0.00e+00	1074.00
IUUC-Tme-126909	Tuber melanosporum	33.89	3.00e-103	369.00
IUUC-Tbe-127261	Tupaia belangeri	39.83	5.00e-116	411.00
IUUC-Ttr-128295	Tursiops truncatus	38.25	2.00e-162	565.00
IUUC-Vda-129688	Verticillium dahliae	33.58	5.00e-113	401.00
IUUC-Vpa-130170	Vicugna pacos	37.45	3.00e-146	511.00
IUUC-Xtr-131953	Xenopus tropicalis	46.16	0.00e+00	716.00
IUUC-Xma-133837	Xiphophorus maculatus	45.76	0.00e+00	686.00
IUUC-Yli-134510	Yarrowia lipolytica	34.53	6.00e-105	374.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence