iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Acl-008265

Ensembl Protein ID

CADACLAP00008461

UniProt Accession

A1CEM0; A1CEM0_ASPCL

Genbank Protein ID

EAW11319.1

Protein Name

HECT domain protein

Genbank Nucleotide ID

DS027052

Gene Name

ACLA_090120

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADACLAG00008671	CADACLAT00008671	CADACLAP00008461

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	6.50e-70	235.0	953	1341

Active Site

Position(s)	Description	Evidence
1310	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 14   vgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklllgkk 104
           +gEegld+gGv++ef+  ++++  +p++g+f+++e+ + +++ +p s     e l  Fe++G l+ +a+++g  l+++++ +fy++llg k
   Q: 953  EGEEGLDHGGVQQEFFRVVMAAALDPSYGMFTMDERTRVSWF-QPCSL----EPLYKFELFGLLMSLAIYNGVTLPVNFPIAFYRKLLGLK 1038
           47*********************************9999987.66665....6899**********************************9 PP
   S: 105  lsl.edleevdpelykslkeikenaes................................................................ 130
           ++  +++++  pel k l  ++  ++                                                                 
   Q: 1039 VKHlDHIQDGWPELSKGLGDLLTWQDGdvgdvfmrtyefsfeafgsvetvdmekvdkdavwplptgihrkpfilpskswselsdfaktadm 1129
           987799************9999998445566666667777777788888888888999999999999999999999999999999999999 PP
   S: 131  ...........dieelgldltfsvseeilgetkeee..LkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellsl 208
                      d ++++ dl+       +++ +e+     p  e   Vtn+N+ ++vk+++ +   ++i++q++af +Gf++ ++   ls+
   Q: 1130 dlsppcsmaadDADDSSPDLSHR----DIKDHAEHSvpTPPVEEASLVTNKNRAQFVKDYIFWLTDQSIRTQFDAFTRGFYTCLDRAALSI 1216
           99998866665555555555544....3444444443257889999********************************************* PP
   S: 209  FteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrl 298
           Ft+e +++++ G +eid+++l+++++y+gg+ +++p+i+ Fw+++++ s+e+r+++L+FvT s+r+P++G+a+++   fvi+k    d+rl
   Q: 1217 FTPEAFKTVVEGIQEIDIKELERHARYEGGFGPSHPTIRGFWSIVRGYSAEKRARLLEFVTASDRVPVNGIASIM---FVIQKnGVGDARL 1304
           ***************************************************************************...*****66678*** PP
   S: 299  PssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           P+s TCf +L LPeYssk++l+ekL  A e+++gF++
   Q: 1305 PTSLTCFGRLLLPEYSSKKVLEEKLDKALENARGFGV 1341
           ***********************************86 PP

Organism

Aspergillus clavatus

Protein Sequence
(Fasta)

MTRLRGASVS SYDASRSPTG VDRSHLHRSK LPPNAPDVIV ENTIDVSDPA QVLLWYRDER 60
RRQFNLLVRK YKNQLLYGCQ DPACRTPTCA SYRRRVSEGP YRRYTELSAR TLACYLASLD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTAGGC TCCGCGGAGC TTCTGTGAGC TCGTACGATG CTTCTCGTTC TCCGACTGGC 60
GTTGATCGGT CTCATTTACA TCGGTCCAAG CTTCCTCCGA ATGCACCAGA TGTCATTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR032353--AZUL
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF16558--AZUL
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

act:ACLA_090120

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Afl-008437	Aspergillus flavus	63.55	0.00e+00	1330.00
IUUC-Afu-008852	Aspergillus fumigatus	71.09	0.00e+00	1740.00
IUUC-Ani-009330	Aspergillus nidulans	59.89	0.00e+00	1202.00
IUUC-Ang-009616	Aspergillus niger	63.86	0.00e+00	1556.00
IUUC-Aor-010162	Aspergillus oryzae	62.86	0.00e+00	1549.00
IUUC-Ate-010475	Aspergillus terreus	61.61	0.00e+00	1449.00
IUUC-Bgr-012015	Blumeria graminis	37.56	4.00e-146	510.00
IUUC-Bci-013608	Botrytis cinerea	36.70	3.00e-147	514.00
IUUC-Cgl-026488	Colletotrichum gloeosporioides	44.71	9.00e-128	449.00
IUUC-Dse-031435	Dothistroma septosporum	32.11	8.00e-43	167.00
IUUC-Fox-037915	Fusarium oxysporum	39.69	1.00e-135	475.00
IUUC-Fso-038357	Fusarium solani	41.16	2.00e-126	445.00
IUUC-Ggr-039765	Gaeumannomyces graminis	38.77	5.00e-147	514.00
IUUC-Lma-053245	Leptosphaeria maculans	31.01	2.00e-95	342.00
IUUC-Mor-057108	Magnaporthe oryzae	38.39	9.00e-133	466.00
IUUC-Nfi-068554	Neosartorya fischeri	72.74	0.00e+00	1755.00
IUUC-Ncr-068759	Neurospora crassa	38.66	6.00e-129	454.00
IUUC-Pno-094886	Phaeosphaeria nodorum	36.45	4.00e-143	501.00
IUUC-Pte-104055	Pyrenophora teres	33.96	3.00e-82	298.00
IUUC-Pyt-104647	Pyrenophora triticirepentis	33.23	2.00e-87	315.00
IUUC-Ssl-108420	Sclerotinia sclerotiorum	38.00	3.00e-151	527.00
IUUC-Tre-121985	Trichoderma reesei	38.41	9.00e-134	469.00
IUUC-Tvi-122335	Trichoderma virens	37.89	4.00e-130	457.00
IUUC-Tme-127119	Tuber melanosporum	30.16	1.00e-119	422.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence