iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nfi-068330

Ensembl Protein ID

CADNFIAP00007689

UniProt Accession

A1DHW7; A1DHW7_NEOFI

Genbank Protein ID

EAW18974.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase, putative

Genbank Nucleotide ID

DS027696

Gene Name

NFIA_089310

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADNFIAG00007856	CADNFIAT00007856	CADNFIAP00007689

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.50e-95	318.6	659	1418

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgyeq 89
           tGl+NlgNtCYmNS+LQc  +++el+ ++l+  +k++ln +np  ++g+++k++++l++ l+ +  +++++pr+++++++++ + fsgy q
   Q: 659  TGLSNLGNTCYMNSALQCVRSVEELTYYFLNdVYKRDLNPSNPLAHNGDIAKAYANLLRMLYdEAGQSSFAPRQFKHTIGRYGPAFSGYGQ 749
           7******************************99*****************************999999*********************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.........aeekkkkknkslisdlFqgqlksqikclecdnvssreepfld 171
           qD+qEfl flld+l+e+l++ ++kp+ e+ ++++   +d+          ++  k +n+s+i+dlF g +ks+++c+ c++vs  ++pf+ 
   Q: 750  QDSQEFLLFLLDGLQEDLNRIQKKPYIEKPDSTDDMVHDKealkefankCWDIYKARNDSVITDLFAGMYKSTLVCPVCEKVSIIFDPFNN 840
           *****************************9999877777799************************************************* PP
   S: 172  lslpvpgkeetkke............................................................................. 185
           l+l++p ++  +ke                                                                             
   Q: 841  LTLQLPIENLWSKEifffplhrkpvivdveidknasikalkelvakkmgsdpqrlvmaeiykckfykmfdnsasiadcqigqgddiaifev 931
           *********99999***************************************************************************** PP
   S: 186  ........................................................................................... 185
                                                                                                      
   Q: 932  esvptnynpdkrqksyfsygrsdyeeipsfdspkadrmlvpifnrhcrpksnnsgnmqrslfgaplyviisreeaqnydailrkvleavat 1022
           ******************************************************************************************* PP
   S: 186  ........................................................................................... 185
                                                                                                      
   Q: 1023 lttrdilneanikkadeqggtqedsdtvvmneddahsadskiktssvdgedglvdvsmrdasdeadtpspqdikcenadsspgssiapglr 1113
           ******************************************************************************************* PP
   S: 186  ........................................................................................... 185
                                                                                                      
   Q: 1114 slfdmkiiksshevvplgwssvddikdyplmssrvkaqsaskqkttsgtvtdrktsddsdqdgsagsasdsdsdmfsnisrpkavktqtde 1204
           ******************************************************************************************* PP
   S: 186  .................................................................slqdcLesftkeeelegenkyycekc 211
                                                                            +l +cL++f kee l +++++yc++c
   Q: 1205 rplirpgegivldwndqahdalfggdkkdtdglrgsptwtnveripdpelakrrdlrrsrkkrgvTLYECLDEFNKEEILSENDAWYCPRC 1295
           ******************************************************************************************* PP
   S: 212  kkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn 301
           k++++a+kk++l+k P++L++hLkRf  s ++++r k++  v+fp e Ld+s  ++spee++  + +Y+L+av +H+G+l++GHY+ay+kn
   Q: 1296 KEHRRASKKFELWKTPDILVMHLKRF--SASRGFRDKLDVLVDFPVEgLDMSGRVESPEEGK--SLIYDLFAVDNHYGGLGGGHYTAYAKN 1382
           **************************..66679************************9*998..9************************** PP
   S: 302  .ekgkWllfdDskVt.evkeeevleetgstaYvlfYkrr 338
             +g+W +++Ds+V+ +++ ++v++     aY+lfY+rr
   Q: 1383 fMSGEWNEYNDSSVSrPIDPQSVVT---PAAYLLFYRRR 1418
           44566*********835899*****...********996 PP

Organism

Neosartorya fischeri

Protein Sequence
(Fasta)

MNQSSSVSSI VIPLILHHLK NTIEEARDSR RPRLVFICWF IFKTPVRSLS SNHHLLACLF 60
NRPFIVLPRA ATRRAQLTVT TSSTKRRKVA EPRRPGGALP GLSFASQAGR RHSQHPPSDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATCAAT CTTCGTCTGT TTCTTCTATT GTTATTCCTC TTATTCTGCA TCATCTGAAG 60
AACACAATAG AGGAAGCCAG AGACTCAAGA CGACCACGGT GAAATAATAC CTCTCATCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

nfi:NFIA_089310

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000425	Aegilops tauschii	50.00	9.00e-41	160.00
IUUC-Aml-001852	Ailuropoda melanoleuca	36.75	4.00e-64	238.00
IUUC-Atr-002991	Amborella trichopoda	27.89	1.00e-47	182.00
IUUC-Apl-003249	Anas platyrhynchos	38.38	4.00e-65	241.00
IUUC-Aca-004261	Anolis carolinensis	44.41	7.00e-64	237.00
IUUC-Aly-006315	Arabidopsis lyrata	44.35	1.00e-49	189.00
IUUC-Ath-007560	Arabidopsis thaliana	45.85	2.00e-54	206.00
IUUC-Ago-007911	Ashbya gossypii	41.69	5.00e-80	291.00
IUUC-Acl-008284	Aspergillus clavatus	83.76	0.00e+00	2276.00
IUUC-Afl-008507	Aspergillus flavus	73.50	0.00e+00	1903.00
IUUC-Afu-008878	Aspergillus fumigatus	93.99	0.00e+00	2708.00
IUUC-Ani-009479	Aspergillus nidulans	67.85	0.00e+00	1774.00
IUUC-Ang-009562	Aspergillus niger	70.50	0.00e+00	2034.00
IUUC-Aor-009949	Aspergillus oryzae	75.06	0.00e+00	1679.00
IUUC-Ate-010323	Aspergillus terreus	72.25	0.00e+00	1763.00
IUUC-Ame-010757	Astyanax mexicanus	33.53	9.00e-68	249.00
IUUC-Bgr-012277	Blumeria graminis	39.80	8.00e-176	610.00
IUUC-Bta-013128	Bos taurus	27.85	2.00e-68	252.00
IUUC-Bci-013993	Botrytis cinerea	39.78	8.00e-166	576.00
IUUC-Bdi-014013	Brachypodium distachyon	38.89	8.00e-60	223.00
IUUC-Bol-015570	Brassica oleracea	45.88	7.00e-57	213.00
IUUC-Bra-017029	Brassica rapa	45.49	2.00e-57	215.00
IUUC-Cel-018203	Caenorhabditis elegans	43.08	2.00e-54	206.00
IUUC-Cja-018798	Callithrix jacchus	36.86	1.00e-60	226.00
IUUC-Cfa-020599	Canis familiaris	37.70	4.00e-60	224.00
IUUC-Cpo-022144	Cavia porcellus	37.68	2.00e-59	222.00
IUUC-Cre-022582	Chlamydomonas reinhardtii	50.53	2.00e-49	187.00
IUUC-Csa-023828	Chlorocebus sabaeus	39.15	3.00e-64	238.00
IUUC-Cho-024595	Choloepus hoffmanni	37.64	3.00e-60	225.00
IUUC-Cin-025292	Ciona intestinalis	31.26	5.00e-61	228.00
IUUC-Csv-026109	Ciona savignyi	30.79	2.00e-63	235.00
IUUC-Cgl-026741	Colletotrichum gloeosporioides	36.72	3.00e-159	555.00
IUUC-Cne-026852	Cryptococcus neoformans	38.62	5.00e-66	244.00
IUUC-Cme-027338	Cyanidioschyzon merolae	47.19	1.00e-55	209.00
IUUC-Dre-027869	Danio rerio	38.08	3.00e-66	245.00
IUUC-Dno-029025	Dasypus novemcinctus	28.43	1.00e-67	249.00
IUUC-Dor-030384	Dipodomys ordii	38.19	9.00e-61	226.00
IUUC-Dse-031432	Dothistroma septosporum	41.16	1.00e-154	539.00
IUUC-Dme-032094	Drosophila melanogaster	35.55	4.00e-40	159.00
IUUC-Ete-032970	Echinops telfairi	51.28	9.00e-53	200.00
IUUC-Eca-033271	Equus caballus	36.02	9.00e-65	240.00
IUUC-Eeu-034488	Erinaceus europaeus	36.75	1.00e-63	236.00
IUUC-Fca-035552	Felis catus	27.85	2.00e-68	252.00
IUUC-Fal-037634	Ficedula albicollis	37.72	2.00e-59	222.00
IUUC-Fox-037986	Fusarium oxysporum	36.30	2.00e-152	531.00
IUUC-Fso-038291	Fusarium solani	39.32	1.00e-171	595.00
IUUC-Gmo-038866	Gadus morhua	39.04	4.00e-68	251.00
IUUC-Ggr-039740	Gaeumannomyces graminis	41.30	2.00e-172	598.00
IUUC-Gga-041146	Gallus gallus	38.60	3.00e-66	245.00
IUUC-Gac-042631	Gasterosteus aculeatus	39.25	3.00e-66	244.00
IUUC-Gma-043077	Glycine max	44.87	1.00e-58	219.00
IUUC-Ggo-045337	Gorilla gorilla	44.28	4.00e-60	224.00
IUUC-Hsa-045669	Homo sapiens	44.28	7.00e-60	224.00
IUUC-Hvu-047103	Hordeum vulgare	49.40	1.00e-40	159.00
IUUC-Itr-048306	Ictidomys tridecemlineatus	27.85	8.00e-69	253.00
IUUC-Kpa-049332	Komagataella pastoris	40.99	1.00e-80	293.00
IUUC-Lch-050107	Latimeria chalumnae	32.94	6.00e-68	250.00
IUUC-Lpe-051424	Leersia perrieri	30.96	9.00e-63	233.00
IUUC-Loc-052105	Lepisosteus oculatus	33.87	3.00e-58	218.00
IUUC-Lma-052981	Leptosphaeria maculans	40.13	0.00e+00	649.00
IUUC-Laf-053803	Loxodonta africana	37.16	3.00e-59	221.00
IUUC-Mcc-054881	Macaca mulatta	39.15	3.00e-64	238.00
IUUC-Meu-056742	Macropus eugenii	43.12	2.00e-59	222.00
IUUC-Mor-056985	Magnaporthe oryzae	39.45	2.00e-162	565.00
IUUC-Mpo-057486	Magnaporthe poae	40.30	4.00e-163	567.00
IUUC-Mtr-058138	Medicago truncatula	45.04	3.00e-57	215.00
IUUC-Mla-058848	Melampsora laricipopulina	31.39	5.00e-87	315.00
IUUC-Mga-060162	Meleagris gallopavo	38.60	3.00e-66	244.00
IUUC-Mvi-060324	Microbotryum violaceum	41.21	9.00e-77	280.00
IUUC-Mmr-061400	Microcebus murinus	38.87	6.00e-64	237.00
IUUC-Mdo-062107	Monodelphis domestica	37.67	1.00e-63	236.00
IUUC-Mmu-063960	Mus musculus	37.16	2.00e-60	226.00
IUUC-Mac-064956	Musa acuminata	46.27	4.00e-60	224.00
IUUC-Mpu-066507	Mustela putorius furo	38.46	7.00e-65	240.00
IUUC-Mlu-068000	Myotis lucifugus	37.01	6.00e-65	240.00
IUUC-Ncr-068879	Neurospora crassa	41.00	6.00e-180	623.00
IUUC-Nle-070010	Nomascus leucogenys	44.28	4.00e-60	224.00
IUUC-Opr-071212	Ochotona princeps	36.75	3.00e-64	238.00
IUUC-Ont-072573	Oreochromis niloticus	28.87	3.00e-71	261.00
IUUC-Oan-073363	Ornithorhynchus anatinus	43.75	1.00e-58	219.00
IUUC-Ocu-074066	Oryctolagus cuniculus	34.61	1.00e-64	239.00
IUUC-Oba-075427	Oryza barthii	54.45	6.00e-57	214.00
IUUC-Obr-076902	Oryza brachyantha	34.50	6.00e-61	227.00
IUUC-Ogl-077803	Oryza glaberrima	50.00	3.00e-40	157.00
IUUC-Ogu-078422	Oryza glumaepatula	54.45	6.00e-57	214.00
IUUC-Oin-079453	Oryza indica	43.01	6.00e-60	223.00
IUUC-Olo-080315	Oryza longistaminata	35.21	1.00e-60	226.00
IUUC-Ome-081271	Oryza meridionalis	35.22	2.00e-60	226.00
IUUC-Oni-082834	Oryza nivara	54.45	5.00e-57	214.00
IUUC-Opu-083691	Oryza punctata	33.04	4.00e-56	211.00
IUUC-Oru-084820	Oryza rufipogon	54.45	6.00e-57	214.00
IUUC-Osa-086139	Oryza sativa	34.98	4.00e-60	224.00
IUUC-Ola-086553	Oryzias latipes	29.08	2.00e-71	262.00
IUUC-Olu-087717	Ostreococcus lucimarinus	39.45	1.00e-54	206.00
IUUC-Oga-089022	Otolemur garnettii	28.12	2.00e-69	256.00
IUUC-Oar-089732	Ovis aries	38.46	1.00e-64	239.00
IUUC-Ptr-091319	Pan troglodytes	27.85	9.00e-69	253.00
IUUC-Pan-092292	Papio anubis	39.15	3.00e-64	238.00
IUUC-Psi-093849	Pelodiscus sinensis	37.27	2.00e-64	239.00
IUUC-Pma-094268	Petromyzon marinus	38.75	3.00e-65	241.00
IUUC-Pno-094890	Phaeosphaeria nodorum	40.08	0.00e+00	653.00
IUUC-Pfo-097060	Poecilia formosa	28.83	3.00e-72	265.00
IUUC-Pab-098522	Pongo abelii	44.28	2.00e-60	225.00
IUUC-Pop-099313	Populus trichocarpa	44.19	4.00e-59	221.00
IUUC-Pca-100161	Procavia capensis	35.50	8.00e-59	220.00
IUUC-Ppe-101587	Prunus persica	44.53	2.00e-56	212.00
IUUC-Pva-103244	Pteropus vampyrus	35.78	2.00e-64	239.00
IUUC-Pgr-103546	Puccinia graminis	29.90	9.00e-71	260.00
IUUC-Ptt-103847	Puccinia triticina	41.12	2.00e-64	239.00
IUUC-Pte-104102	Pyrenophora teres	38.33	1.00e-179	623.00
IUUC-Pyt-104812	Pyrenophora triticirepentis	44.98	1.00e-140	493.00
IUUC-Rno-106081	Rattus norvegicus	37.70	9.00e-63	233.00
IUUC-Sce-106170	Saccharomyces cerevisiae	39.35	3.00e-72	265.00
IUUC-Sha-107393	Sarcophilus harrisii	37.67	8.00e-64	237.00
IUUC-Sja-107752	Schizosaccharomyces japonicus	33.91	1.00e-95	342.00
IUUC-Spo-108291	Schizosaccharomyces pombe	38.16	9.00e-129	452.00
IUUC-Smo-109356	Selaginella moellendorffii	45.10	3.00e-59	221.00
IUUC-Sit-109948	Setaria italica	45.95	8.00e-60	223.00
IUUC-Sly-111746	Solanum lycopersicum	44.98	6.00e-59	221.00
IUUC-Stu-112671	Solanum tuberosum	44.61	5.00e-58	217.00
IUUC-Sar-113498	Sorex araneus	36.75	9.00e-65	240.00
IUUC-Sbi-114874	Sorghum bicolor	39.44	7.00e-61	227.00
IUUC-Sre-115130	Sporisorium reilianum	41.19	3.00e-81	295.00
IUUC-Ssc-115637	Sus scrofa	37.43	2.00e-60	226.00
IUUC-Tgu-116529	Taeniopygia guttata	38.12	3.00e-65	241.00
IUUC-Tru-118298	Takifugu rubripes	28.19	1.00e-70	259.00
IUUC-Tsy-119414	Tarsius syrichta	39.44	1.00e-64	239.00
IUUC-Tni-120093	Tetraodon nigroviridis	37.57	1.00e-64	239.00
IUUC-Tca-121001	Theobroma cacao	32.09	3.00e-62	231.00
IUUC-Tre-121888	Trichoderma reesei	39.68	7.00e-164	570.00
IUUC-Tvi-122422	Trichoderma virens	36.76	9.00e-156	543.00
IUUC-Tae-125401	Triticum aestivum	45.53	3.00e-59	221.00
IUUC-Tur-126149	Triticum urartu	50.00	1.00e-40	160.00
IUUC-Tme-127062	Tuber melanosporum	36.93	5.00e-153	533.00
IUUC-Tbe-127672	Tupaia belangeri	37.01	3.00e-64	238.00
IUUC-Ttr-128778	Tursiops truncatus	36.78	5.00e-59	221.00
IUUC-Uma-129498	Ustilago maydis	35.37	7.00e-130	457.00
IUUC-Vda-129781	Verticillium dahliae	39.28	4.00e-159	554.00
IUUC-Vpa-130571	Vicugna pacos	36.56	3.00e-60	225.00
IUUC-Vvi-131010	Vitis vinifera	34.53	5.00e-62	231.00
IUUC-Xtr-132305	Xenopus tropicalis	44.68	3.00e-64	238.00
IUUC-Xma-133176	Xiphophorus maculatus	38.87	6.00e-67	247.00
IUUC-Yli-134392	Yarrowia lipolytica	35.26	1.00e-77	283.00
IUUC-Zma-135699	Zea mays	35.19	6.00e-61	227.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence