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Tag Content
UUCD2 ID IUUC-Cfa-021243
UUCD1 version UUC-CaF-00982
Ensembl Protein ID ENSCAFP00000022332.3
UniProt Accession E2RH35; E2RH35_CANLF
Genbank Protein ID ENSCAFP00000022332
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAEX03016119
Gene Name USP8
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000015145.3 ENSCAFT00000024054.3 ENSCAFP00000022332.3
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 4.10e-109 365.1 775 1105
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtCYmNS+LQcL n p l++++++  ++ ++n++n  ++kge+++++  ++++lw+++ +++sp++++ +++k++ +f g
   Q: 775  TGLRNLGNTCYMNSILQCLCNAPHLADYFNRnCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAG 861
           7*****************************9899***************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeee...dkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfl 170
           y+qqD+qE+l fl+d+l+e+l+k +n ++++ee++   d+ ++ ++a++k+k+ n+s+i+ lFqgq+ks+++cl+c+++s ++e f+
   Q: 862  YSQQDSQELLLFLMDGLHEDLNKADNRKRHKEENNdhlDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFM 948
           *********************9855555555444411145566667***************************************** PP
   S: 171  dlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpl 257
           +lslp+ + +++   +lqdcL+ f+kee+l+++n++yc++c+ ++++ kk++++klP+vL +hLkRfs++ + ++ +k++++v+fpl
   Q: 949  YLSLPLASTSKC---TLQDCLRLFSKEEKLTDNNRFYCSHCRTRRDSLKKIEIWKLPPVLLVHLKRFSYDGR-WK-QKLQTSVDFPL 1030
           ***********9...******************************************************996.55.6********** PP
   S: 258  e.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           e Ldls++++ p+++    kkY+L++v +H+G+l++GHY+ay+kn  ++ W++fdD++V+ ++ ++v++   s aY+lfY+
   Q: 1031 EnLDLSQYVIGPKNN---LKKYNLFSVSNHYGGLDGGHYTAYCKNAARQrWFKFDDHEVSDISVSSVKS---SAAYILFYT 1105
           ***********9988...69*************************88888*******************...********8 PP
   
Organism Canis familiaris
Protein Sequence
(Fasta)
MPAVASVPKE LYLSSSLKDL NKKTEVKPEK ISTKNYVQSA LKIFKTAEES RLDRDEERAY 60
VLYMKYVTVY NLIKKRPDFK QQQDYFHSIL GLANIKKAIE EAERLSESLK LRYEEAEVRK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-021243|DUB,USP|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AAAAGAACTA CTTTTAATAA GGTACACCAT CCATTGTCAA AGTGGAAAAG TAAAGATTAT 60
TCATCATGCC TGCTGTGGCT TCAGTTCCTA AAGAACTCTA CCTCAGTTCT TCACTAAAAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-021243|DUB,USP|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR001763--Rhodanese-like_dom
IPR015063--USP8_dimer
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS50206--RHODANESE_3
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00581--Rhodanese
PF00443--UCH
PF08969--USP8_dimer
SMART

SM00450--RHOD
Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0031313--C:extrinsic component of endosome membrane
GO:0019897--C:extrinsic component of plasma membrane
GO:0030496--C:midbody
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007032--P:endosome organization
GO:0000281--P:mitotic cytokinesis
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG cfa:478299
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001661 Ailuropoda melanoleuca 96.96 0.00e+00 2001.00
IUUC-Apl-003226 Anas platyrhynchos 63.90 0.00e+00 1333.00
IUUC-Aca-004936 Anolis carolinensis 65.95 0.00e+00 1308.00
IUUC-Ago-007959 Ashbya gossypii 35.62 1.00e-54 208.00
IUUC-Acl-008102 Aspergillus clavatus 31.32 1.00e-50 195.00
IUUC-Afl-008604 Aspergillus flavus 32.05 2.00e-49 191.00
IUUC-Afu-009001 Aspergillus fumigatus 31.11 9.00e-50 192.00
IUUC-Ani-009291 Aspergillus nidulans 31.16 1.00e-49 191.00
IUUC-Ang-009844 Aspergillus niger 32.43 9.00e-49 188.00
IUUC-Aor-010098 Aspergillus oryzae 32.05 7.00e-49 189.00
IUUC-Ate-010585 Aspergillus terreus 31.64 8.00e-49 189.00
IUUC-Ame-011029 Astyanax mexicanus 60.28 1.00e-70 259.00
IUUC-Bta-013008 Bos taurus 90.24 0.00e+00 1847.00
IUUC-Bol-015281 Brassica oleracea 37.75 3.00e-47 182.00
IUUC-Bra-017228 Brassica rapa 39.10 1.00e-48 187.00
IUUC-Cel-018482 Caenorhabditis elegans 33.82 8.00e-52 198.00
IUUC-Cja-019173 Callithrix jacchus 90.43 0.00e+00 1885.00
IUUC-Cpo-021522 Cavia porcellus 85.14 0.00e+00 1741.00
IUUC-Cre-022582 Chlamydomonas reinhardtii 44.35 5.00e-82 297.00
IUUC-Csa-023616 Chlorocebus sabaeus 92.01 0.00e+00 1610.00
IUUC-Cho-024381 Choloepus hoffmanni 77.56 0.00e+00 1551.00
IUUC-Cin-025287 Ciona intestinalis 50.13 2.00e-99 357.00
IUUC-Csv-026253 Ciona savignyi 47.79 5.00e-88 319.00
IUUC-Cne-026821 Cryptococcus neoformans 40.17 4.00e-75 276.00
IUUC-Dre-028440 Danio rerio 69.00 0.00e+00 736.00
IUUC-Dno-029039 Dasypus novemcinctus 90.88 0.00e+00 1931.00
IUUC-Dor-031043 Dipodomys ordii 96.55 9.00e-134 471.00
IUUC-Dse-031463 Dothistroma septosporum 27.32 3.00e-41 164.00
IUUC-Dme-032089 Drosophila melanogaster 44.50 2.00e-85 310.00
IUUC-Ete-033040 Echinops telfairi 80.12 0.00e+00 1542.00
IUUC-Eca-033449 Equus caballus 94.18 0.00e+00 1950.00
IUUC-Eeu-034693 Erinaceus europaeus 95.69 2.00e-131 463.00
IUUC-Fca-035794 Felis catus 99.58 0.00e+00 939.00
IUUC-Fal-037322 Ficedula albicollis 69.53 0.00e+00 1437.00
IUUC-Gmo-038584 Gadus morhua 66.46 0.00e+00 660.00
IUUC-Gga-041188 Gallus gallus 83.19 0.00e+00 931.00
IUUC-Gac-041850 Gasterosteus aculeatus 72.46 0.00e+00 735.00
IUUC-Ggo-045565 Gorilla gorilla 91.95 0.00e+00 1928.00
IUUC-Hsa-046438 Homo sapiens 91.86 0.00e+00 1924.00
IUUC-Itr-048883 Ictidomys tridecemlineatus 89.44 0.00e+00 1837.00
IUUC-Kpa-049321 Komagataella pastoris 33.24 5.00e-49 189.00
IUUC-Lch-050485 Latimeria chalumnae 80.04 0.00e+00 869.00
IUUC-Loc-052769 Lepisosteus oculatus 74.95 0.00e+00 776.00
IUUC-Lma-053021 Leptosphaeria maculans 33.04 3.00e-53 204.00
IUUC-Laf-053432 Loxodonta africana 78.47 0.00e+00 1711.00
IUUC-Mcc-055823 Macaca mulatta 91.41 0.00e+00 1921.00
IUUC-Meu-056099 Macropus eugenii 97.77 2.00e-165 577.00
IUUC-Mla-059089 Melampsora laricipopulina 40.18 4.00e-72 266.00
IUUC-Mga-059739 Meleagris gallopavo 83.19 0.00e+00 928.00
IUUC-Mvi-060559 Microbotryum violaceum 41.14 1.00e-77 285.00
IUUC-Mmr-061158 Microcebus murinus 90.15 0.00e+00 1848.00
IUUC-Mdo-061801 Monodelphis domestica 80.25 0.00e+00 1606.00
IUUC-Mmu-063665 Mus musculus 81.47 0.00e+00 1673.00
IUUC-Mpu-066738 Mustela putorius furo 96.24 0.00e+00 1959.00
IUUC-Mlu-067307 Myotis lucifugus 90.72 0.00e+00 1865.00
IUUC-Nfi-068410 Neosartorya fischeri 31.39 4.00e-50 193.00
IUUC-Nle-069314 Nomascus leucogenys 91.50 0.00e+00 1914.00
IUUC-Opr-070378 Ochotona princeps 80.02 0.00e+00 1217.00
IUUC-Ont-071545 Oreochromis niloticus 76.42 0.00e+00 763.00
IUUC-Oan-073537 Ornithorhynchus anatinus 77.02 0.00e+00 1551.00
IUUC-Ocu-074193 Oryctolagus cuniculus 88.81 0.00e+00 1842.00
IUUC-Ola-086622 Oryzias latipes 57.21 0.00e+00 1078.00
IUUC-Oga-088271 Otolemur garnettii 88.21 0.00e+00 1808.00
IUUC-Oar-090431 Ovis aries 90.18 0.00e+00 1854.00
IUUC-Ptr-091339 Pan troglodytes 91.59 0.00e+00 1970.00
IUUC-Pan-091783 Papio anubis 86.20 0.00e+00 989.00
IUUC-Psi-093187 Pelodiscus sinensis 63.20 5.00e-155 541.00
IUUC-Pma-094626 Petromyzon marinus 58.43 9.00e-142 496.00
IUUC-Pfo-096463 Poecilia formosa 75.41 0.00e+00 754.00
IUUC-Pab-097645 Pongo abelii 91.50 0.00e+00 1920.00
IUUC-Pva-103222 Pteropus vampyrus 86.35 0.00e+00 961.00
IUUC-Pgr-103408 Puccinia graminis 35.92 2.00e-54 207.00
IUUC-Ptt-103699 Puccinia triticina 45.45 2.00e-67 251.00
IUUC-Pte-104348 Pyrenophora teres 28.83 2.00e-39 157.00
IUUC-Pyt-104711 Pyrenophora triticirepentis 31.11 9.00e-51 195.00
IUUC-Rno-105510 Rattus norvegicus 81.11 0.00e+00 1696.00
IUUC-Sce-106166 Saccharomyces cerevisiae 35.26 3.00e-51 197.00
IUUC-Sha-106879 Sarcophilus harrisii 79.93 0.00e+00 1584.00
IUUC-Sja-107836 Schizosaccharomyces japonicus 36.29 3.00e-48 186.00
IUUC-Sar-113019 Sorex araneus 85.42 0.00e+00 1798.00
IUUC-Sre-115031 Sporisorium reilianum 37.05 9.00e-69 255.00
IUUC-Ssc-116334 Sus scrofa 90.80 0.00e+00 1898.00
IUUC-Tgu-117062 Taeniopygia guttata 81.03 0.00e+00 914.00
IUUC-Tru-117908 Takifugu rubripes 58.02 0.00e+00 1158.00
IUUC-Tsy-118867 Tarsius syrichta 87.22 0.00e+00 1083.00
IUUC-Tni-120206 Tetraodon nigroviridis 54.94 0.00e+00 1048.00
IUUC-Tme-127144 Tuber melanosporum 40.00 1.00e-78 288.00
IUUC-Tbe-127877 Tupaia belangeri 86.83 2.00e-102 367.00
IUUC-Ttr-128580 Tursiops truncatus 88.36 0.00e+00 1785.00
IUUC-Uma-129340 Ustilago maydis 35.75 6.00e-71 263.00
IUUC-Vpa-130541 Vicugna pacos 92.39 0.00e+00 1918.00
IUUC-Xtr-132161 Xenopus tropicalis 59.09 0.00e+00 1200.00
IUUC-Xma-134271 Xiphophorus maculatus 75.41 0.00e+00 752.00
IUUC-Yli-134561 Yarrowia lipolytica 35.92 5.00e-60 226.00
Created Date 25-Jun-2017

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