iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-073773

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02044517

Gene Name

UBA3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000008169.2	ENSOCUT00000008172.2	ENSOCUP00000007065.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	9.30e-99	331.5	66	256

Active Site

Position(s)	Description	Evidence
237	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 15   klksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleee 103
            l+++kvl++GagglGcEllKnL+l+G+++i+v+Dmdt++vsnlnrqFLfr++dvg++KAevaae+l++++p++nv++h ++i++  ++
   Q: 66   LLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDVGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFSDT 154
           589***********************************************************************************999 PP
   S: 104  ivFfkkfdvVvlaldnrearrkvnrlclna............rvpliesgtlGllGqvrviikgltecyscsd..dppqktiPfctlke 178
             F+++f+++v++ld++ arr++n +++++             +pli++gt+G++G++rvi++g+t+c++c+   +ppq+++P+ct+++
   Q: 155  --FYRQFHIIVCGLDSIIARRWINGMLISLlnyedgvldpssIIPLIDGGTEGFKGNARVILPGMTACIECTLelYPPQVNFPMCTIAS 241
           ..***************************9*********************************************************** PP
   S: 179  tpnaaehtiewavlf 193
           +p+ +eh+ie+++++
   Q: 242  MPRLPEHCIEYVRML 256
           ***********9443 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MADGEEPEKK RRRIEELLAE KMAVDGGCGD TGDWEGRWNH VKKFLERSGP FTHPDFEPST 60
ESLQFLLDTC KVLVIGAGGL GCELLKNLAL SGFRQIHVID MDTIDVSNLN RQFLFRPKDV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGATG GCGAGGAGCC GTAAGTACCG GGGCTCTGCC GGCGCGCCGG GCTGGGCTGG 60
GTTGTGAGAG AGCGCGGCGG AGGGCGGTCG CCGCCCCCAC CCGGGGTCCC CTCCACTCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014929--E2_binding
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR030468--Uba3
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF08825--E2_bind
PF00899--ThiF

SMART

SM01181--E2_bind

Gene Ontology

GO:0005634--C:nucleus
GO:0016881--F:acid-amino acid ligase activity
GO:0005524--F:ATP binding
GO:0019781--F:NEDD8 activating enzyme activity
GO:0007113--P:endomitotic cell cycle
GO:0045116--P:protein neddylation
GO:0051726--P:regulation of cell cycle

KEGG

ocu:100343309

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001124	Aegilops tauschii	48.01	3.00e-81	295.00
IUUC-Aml-001578	Ailuropoda melanoleuca	98.68	0.00e+00	941.00
IUUC-Atr-002591	Amborella trichopoda	50.37	6.00e-91	327.00
IUUC-Apl-003671	Anas platyrhynchos	90.56	0.00e+00	863.00
IUUC-Aca-004749	Anolis carolinensis	91.10	0.00e+00	827.00
IUUC-Aly-005747	Arabidopsis lyrata	47.89	2.00e-97	349.00
IUUC-Ath-006623	Arabidopsis thaliana	48.14	3.00e-97	348.00
IUUC-Ago-007934	Ashbya gossypii	45.28	3.00e-73	268.00
IUUC-Acl-008047	Aspergillus clavatus	49.88	8.00e-122	430.00
IUUC-Afl-008615	Aspergillus flavus	43.57	1.00e-78	286.00
IUUC-Afu-008996	Aspergillus fumigatus	50.70	3.00e-115	408.00
IUUC-Ani-009281	Aspergillus nidulans	43.53	3.00e-84	305.00
IUUC-Ang-009539	Aspergillus niger	50.82	3.00e-112	398.00
IUUC-Aor-010151	Aspergillus oryzae	48.21	2.00e-109	389.00
IUUC-Ate-010502	Aspergillus terreus	51.06	6.00e-114	404.00
IUUC-Ame-011837	Astyanax mexicanus	86.77	0.00e+00	791.00
IUUC-Bgr-012068	Blumeria graminis	50.48	2.00e-113	402.00
IUUC-Bta-013003	Bos taurus	98.49	0.00e+00	916.00
IUUC-Bci-013983	Botrytis cinerea	53.76	5.00e-124	437.00
IUUC-Bdi-014429	Brachypodium distachyon	49.25	1.00e-88	320.00
IUUC-Bol-015813	Brassica oleracea	48.88	2.00e-89	322.00
IUUC-Bra-018023	Brassica rapa	48.14	1.00e-86	313.00
IUUC-Cel-018684	Caenorhabditis elegans	53.50	1.00e-128	452.00
IUUC-Cja-019200	Callithrix jacchus	98.92	0.00e+00	912.00
IUUC-Cfa-021038	Canis familiaris	98.87	0.00e+00	917.00
IUUC-Cre-022778	Chlamydomonas reinhardtii	49.51	5.00e-108	384.00
IUUC-Csa-024079	Chlorocebus sabaeus	98.70	0.00e+00	920.00
IUUC-Cho-025052	Choloepus hoffmanni	90.05	0.00e+00	819.00
IUUC-Cin-025113	Ciona intestinalis	68.55	0.00e+00	626.00
IUUC-Csv-026231	Ciona savignyi	67.44	0.00e+00	628.00
IUUC-Cgl-026535	Colletotrichum gloeosporioides	51.38	1.00e-124	439.00
IUUC-Cne-026850	Cryptococcus neoformans	48.47	2.00e-108	385.00
IUUC-Cme-027275	Cyanidioschyzon merolae	36.48	2.00e-68	253.00
IUUC-Dre-028751	Danio rerio	86.77	0.00e+00	804.00
IUUC-Dno-029571	Dasypus novemcinctus	97.74	0.00e+00	909.00
IUUC-Dor-030395	Dipodomys ordii	97.19	0.00e+00	886.00
IUUC-Dse-031329	Dothistroma septosporum	45.96	3.00e-104	371.00
IUUC-Dme-031776	Drosophila melanogaster	63.57	1.00e-160	559.00
IUUC-Ete-032894	Echinops telfairi	77.65	1.00e-70	259.00
IUUC-Eca-034389	Equus caballus	95.46	0.00e+00	918.00
IUUC-Eeu-035152	Erinaceus europaeus	86.07	0.00e+00	691.00
IUUC-Fca-036032	Felis catus	98.65	0.00e+00	922.00
IUUC-Fal-037506	Ficedula albicollis	90.06	0.00e+00	858.00
IUUC-Fox-037871	Fusarium oxysporum	54.11	2.00e-110	392.00
IUUC-Fso-038350	Fusarium solani	52.31	2.00e-122	432.00
IUUC-Gmo-039246	Gadus morhua	84.02	0.00e+00	791.00
IUUC-Ggr-039859	Gaeumannomyces graminis	53.36	3.00e-120	425.00
IUUC-Gga-040843	Gallus gallus	88.12	0.00e+00	825.00
IUUC-Gac-042601	Gasterosteus aculeatus	84.02	0.00e+00	806.00
IUUC-Gma-042744	Glycine max	50.39	2.00e-88	319.00
IUUC-Ggo-044788	Gorilla gorilla	98.71	0.00e+00	913.00
IUUC-Hsa-045849	Homo sapiens	99.14	0.00e+00	921.00
IUUC-Hvu-047819	Hordeum vulgare	51.28	1.00e-82	300.00
IUUC-Itr-047863	Ictidomys tridecemlineatus	98.19	0.00e+00	913.00
IUUC-Kpa-049393	Komagataella pastoris	54.71	2.00e-103	369.00
IUUC-Lch-049471	Latimeria chalumnae	90.81	0.00e+00	837.00
IUUC-Lpe-051297	Leersia perrieri	48.56	9.00e-98	350.00
IUUC-Loc-052910	Lepisosteus oculatus	88.31	0.00e+00	813.00
IUUC-Lma-053181	Leptosphaeria maculans	50.11	5.00e-121	427.00
IUUC-Laf-054314	Loxodonta africana	97.43	0.00e+00	908.00
IUUC-Mcc-054870	Macaca mulatta	99.10	0.00e+00	918.00
IUUC-Meu-056574	Macropus eugenii	78.69	5.00e-131	460.00
IUUC-Mor-056919	Magnaporthe oryzae	54.19	5.00e-124	437.00
IUUC-Mpo-057614	Magnaporthe poae	54.68	7.00e-115	407.00
IUUC-Mtr-058110	Medicago truncatula	50.13	3.00e-89	322.00
IUUC-Mla-058949	Melampsora laricipopulina	53.06	8.00e-117	413.00
IUUC-Mga-059455	Meleagris gallopavo	90.50	0.00e+00	859.00
IUUC-Mvi-060270	Microbotryum violaceum	50.90	5.00e-119	421.00
IUUC-Mmr-061155	Microcebus murinus	92.95	0.00e+00	884.00
IUUC-Mdo-062037	Monodelphis domestica	95.68	0.00e+00	861.00
IUUC-Mmu-063670	Mus musculus	98.92	0.00e+00	917.00
IUUC-Mac-064711	Musa acuminata	48.64	3.00e-87	315.00
IUUC-Mpu-066734	Mustela putorius furo	98.20	0.00e+00	911.00
IUUC-Mlu-067068	Myotis lucifugus	98.06	0.00e+00	878.00
IUUC-Nfi-068349	Neosartorya fischeri	50.47	2.00e-114	405.00
IUUC-Ncr-068626	Neurospora crassa	53.00	2.00e-107	382.00
IUUC-Nle-069366	Nomascus leucogenys	91.03	0.00e+00	826.00
IUUC-Opr-070993	Ochotona princeps	93.85	4.00e-69	255.00
IUUC-Ont-072196	Oreochromis niloticus	85.99	0.00e+00	802.00
IUUC-Oan-073511	Ornithorhynchus anatinus	93.52	0.00e+00	881.00
IUUC-Oba-075726	Oryza barthii	44.79	1.00e-85	309.00
IUUC-Obr-076286	Oryza brachyantha	47.60	1.00e-94	339.00
IUUC-Ogu-078473	Oryza glumaepatula	44.79	1.00e-85	310.00
IUUC-Oin-079393	Oryza indica	49.75	4.00e-100	358.00
IUUC-Olo-080446	Oryza longistaminata	46.39	3.00e-89	322.00
IUUC-Ome-081737	Oryza meridionalis	47.01	4.00e-89	321.00
IUUC-Oni-082853	Oryza nivara	44.79	1.00e-85	309.00
IUUC-Opu-083590	Oryza punctata	48.80	2.00e-99	356.00
IUUC-Oru-084184	Oryza rufipogon	44.79	1.00e-85	309.00
IUUC-Osa-085402	Oryza sativa	49.75	4.00e-100	358.00
IUUC-Ola-086615	Oryzias latipes	78.19	0.00e+00	736.00
IUUC-Olu-087738	Ostreococcus lucimarinus	48.64	2.00e-93	335.00
IUUC-Oga-088101	Otolemur garnettii	98.49	0.00e+00	915.00
IUUC-Oar-090293	Ovis aries	97.10	0.00e+00	907.00
IUUC-Ptr-090503	Pan troglodytes	99.14	0.00e+00	921.00
IUUC-Pan-092477	Papio anubis	96.78	0.00e+00	890.00
IUUC-Psi-093442	Pelodiscus sinensis	91.38	0.00e+00	857.00
IUUC-Pma-094247	Petromyzon marinus	80.80	0.00e+00	768.00
IUUC-Pno-094780	Phaeosphaeria nodorum	49.37	3.00e-114	405.00
IUUC-Ppa-095338	Physcomitrella patens	50.12	5.00e-116	410.00
IUUC-Pfo-097137	Poecilia formosa	85.56	0.00e+00	805.00
IUUC-Pab-098060	Pongo abelii	98.70	0.00e+00	880.00
IUUC-Pop-099470	Populus trichocarpa	47.69	3.00e-94	338.00
IUUC-Pca-100500	Procavia capensis	79.91	0.00e+00	738.00
IUUC-Ppe-102008	Prunus persica	48.73	8.00e-86	310.00
IUUC-Pva-103095	Pteropus vampyrus	99.13	3.00e-128	451.00
IUUC-Pgr-103666	Puccinia graminis	50.58	8.00e-115	407.00
IUUC-Ptt-103901	Puccinia triticina	51.06	3.00e-117	415.00
IUUC-Pte-104198	Pyrenophora teres	48.98	2.00e-119	422.00
IUUC-Pyt-104792	Pyrenophora triticirepentis	48.30	3.00e-117	414.00
IUUC-Rno-105446	Rattus norvegicus	98.92	0.00e+00	917.00
IUUC-Sce-106355	Saccharomyces cerevisiae	42.99	1.00e-71	263.00
IUUC-Sha-106664	Sarcophilus harrisii	95.50	0.00e+00	861.00
IUUC-Sja-107982	Schizosaccharomyces japonicus	43.49	1.00e-99	356.00
IUUC-Spo-108345	Schizosaccharomyces pombe	43.54	1.00e-98	353.00
IUUC-Ssl-108540	Sclerotinia sclerotiorum	49.18	9.00e-107	380.00
IUUC-Smo-109133	Selaginella moellendorffii	49.53	3.00e-115	408.00
IUUC-Sit-109724	Setaria italica	49.50	4.00e-91	328.00
IUUC-Sly-110916	Solanum lycopersicum	48.84	3.00e-95	342.00
IUUC-Stu-112236	Solanum tuberosum	48.59	5.00e-95	341.00
IUUC-Sar-113044	Sorex araneus	97.51	0.00e+00	816.00
IUUC-Sbi-114276	Sorghum bicolor	49.63	3.00e-91	328.00
IUUC-Sre-114963	Sporisorium reilianum	51.75	1.00e-117	416.00
IUUC-Ssc-116301	Sus scrofa	97.65	0.00e+00	910.00
IUUC-Tgu-117265	Taeniopygia guttata	90.06	0.00e+00	858.00
IUUC-Tru-117526	Takifugu rubripes	84.30	0.00e+00	788.00
IUUC-Tsy-119483	Tarsius syrichta	98.07	0.00e+00	848.00
IUUC-Tni-120363	Tetraodon nigroviridis	84.91	0.00e+00	783.00
IUUC-Tca-121731	Theobroma cacao	48.87	8.00e-88	317.00
IUUC-Tre-122221	Trichoderma reesei	53.58	2.00e-111	395.00
IUUC-Tvi-122352	Trichoderma virens	51.74	2.00e-123	435.00
IUUC-Tae-123864	Triticum aestivum	48.56	2.00e-90	325.00
IUUC-Tur-126070	Triticum urartu	46.13	5.00e-71	261.00
IUUC-Tme-127199	Tuber melanosporum	50.65	4.00e-109	387.00
IUUC-Tbe-128076	Tupaia belangeri	98.64	0.00e+00	915.00
IUUC-Ttr-128695	Tursiops truncatus	82.58	0.00e+00	745.00
IUUC-Uma-129638	Ustilago maydis	51.05	2.00e-117	415.00
IUUC-Vda-129963	Verticillium dahliae	52.42	6.00e-115	407.00
IUUC-Vpa-130637	Vicugna pacos	90.95	0.00e+00	823.00
IUUC-Vvi-131613	Vitis vinifera	48.72	8.00e-85	307.00
IUUC-Xtr-132924	Xenopus tropicalis	89.49	0.00e+00	819.00
IUUC-Xma-133356	Xiphophorus maculatus	85.56	0.00e+00	806.00
IUUC-Yli-134365	Yarrowia lipolytica	52.43	1.00e-110	392.00
IUUC-Zma-135941	Zea mays	45.12	6.00e-86	311.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence