iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afu-008820

Ensembl Protein ID

CADAFUAP00004585

UniProt Accession

Q4WZP2; CSN5_ASPFU

Genbank Protein ID

EAL93923.2

Protein Name

COP9 signalosome complex subunit 5

Genbank Nucleotide ID

AAHF01000001

Gene Name

AFUA_2G16250; csn5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADAFUAG00004585	CADAFUAT00004585	CADAFUAP00004585

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/JAMM	4.50e-08	31.9	134	147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/JAMM

   S: 1    HSHPgftcwlSsVD 14
           HSHPg++cwlS++D
   Q: 134  HSHPGYGCWLSGID 147
           *************9 PP

Organism

Aspergillus fumigatus

Functional Description
(View)

Catalytic component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.

Protein Sequence
(Fasta)

MQAAQQSWEL ENTISLIDPQ RDALYRYDEE THKALSAARP WAKDPHYFKS IRISAVALIK 60
MTMHARSGGS LEVMGLMQGY ILPETFVVTD AFRLPVEGTE TRVNAQEEAN EYMVSYLQSC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGGCTG CACAGCAGTC CTGGGGTTCG TACTCAAATG ACCCACTTGG CATCGCTTTC 60
CGATGAGCTA CTGACACCGC GGCTTTCTGC CCCTCCCTCA GAGCTCGAAA ACACCATCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0482--Metalloprotease
KW-0539--Nucleus
KW-0645--Protease
KW-1185--Reference proteome
KW-0736--Signalosome
KW-0862--Zinc

Interpro

IPR000555--JAMM/MPN+_dom

Pfam

PF01398--JAB

SMART

SM00232--JAB_MPN

Gene Ontology

GO:0008180--C:COP9 signalosome
GO:0005737--C:cytoplasm
GO:0046872--F:metal ion binding
GO:0008237--F:metallopeptidase activity

KEGG

afm:AFUA_2G16250

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000468	Aegilops tauschii	55.26	4.00e-98	349.00
IUUC-Aml-001429	Ailuropoda melanoleuca	55.05	2.00e-93	333.00
IUUC-Atr-003048	Amborella trichopoda	54.30	3.00e-101	359.00
IUUC-Apl-003610	Anas platyrhynchos	55.41	4.00e-87	312.00
IUUC-Aca-004662	Anolis carolinensis	58.25	7.00e-84	301.00
IUUC-Aly-005914	Arabidopsis lyrata	52.34	5.00e-98	348.00
IUUC-Ath-007496	Arabidopsis thaliana	54.19	7.00e-99	352.00
IUUC-Ago-007860	Ashbya gossypii	48.15	3.00e-49	187.00
IUUC-Acl-008155	Aspergillus clavatus	93.71	0.00e+00	659.00
IUUC-Ani-009303	Aspergillus nidulans	85.24	2.00e-173	599.00
IUUC-Ang-009617	Aspergillus niger	80.78	6.00e-166	574.00
IUUC-Aor-009888	Aspergillus oryzae	90.06	4.00e-178	614.00
IUUC-Ate-010575	Aspergillus terreus	87.09	3.00e-177	612.00
IUUC-Ame-010617	Astyanax mexicanus	54.68	4.00e-95	339.00
IUUC-Bgr-012019	Blumeria graminis	63.03	6.00e-126	441.00
IUUC-Bta-013211	Bos taurus	55.18	5.00e-94	335.00
IUUC-Bci-013645	Botrytis cinerea	66.36	4.00e-132	462.00
IUUC-Bdi-014727	Brachypodium distachyon	52.94	1.00e-94	337.00
IUUC-Bol-015205	Brassica oleracea	51.91	4.00e-94	336.00
IUUC-Bra-017649	Brassica rapa	51.91	4.00e-94	336.00
IUUC-Cel-018469	Caenorhabditis elegans	50.16	5.00e-95	339.00
IUUC-Cja-019703	Callithrix jacchus	55.18	5.00e-94	335.00
IUUC-Cfa-020181	Canis familiaris	55.18	5.00e-94	335.00
IUUC-Cpo-021499	Cavia porcellus	55.18	5.00e-94	335.00
IUUC-Cre-022735	Chlamydomonas reinhardtii	53.77	2.00e-100	357.00
IUUC-Csa-024200	Chlorocebus sabaeus	55.18	5.00e-94	335.00
IUUC-Cho-024915	Choloepus hoffmanni	56.19	8.00e-62	228.00
IUUC-Cin-025353	Ciona intestinalis	51.65	7.00e-89	318.00
IUUC-Csv-026118	Ciona savignyi	51.82	5.00e-90	322.00
IUUC-Cgl-026511	Colletotrichum gloeosporioides	58.53	1.00e-120	424.00
IUUC-Cne-026988	Cryptococcus neoformans	44.86	2.00e-81	293.00
IUUC-Dre-028134	Danio rerio	54.43	7.00e-94	335.00
IUUC-Dno-029658	Dasypus novemcinctus	55.18	5.00e-94	335.00
IUUC-Dor-031074	Dipodomys ordii	55.18	5.00e-94	335.00
IUUC-Dse-031497	Dothistroma septosporum	58.66	1.00e-114	404.00
IUUC-Dme-032199	Drosophila melanogaster	56.53	1.00e-100	357.00
IUUC-Ete-032739	Echinops telfairi	60.12	2.00e-49	187.00
IUUC-Eca-034095	Equus caballus	55.18	5.00e-94	335.00
IUUC-Eeu-034934	Erinaceus europaeus	63.37	3.00e-85	306.00
IUUC-Fca-035569	Felis catus	55.18	5.00e-94	335.00
IUUC-Fal-037553	Ficedula albicollis	57.75	4.00e-84	302.00
IUUC-Fox-037945	Fusarium oxysporum	59.27	7.00e-119	418.00
IUUC-Fso-038385	Fusarium solani	61.26	6.00e-123	431.00
IUUC-Gmo-039438	Gadus morhua	53.82	3.00e-92	329.00
IUUC-Ggr-039968	Gaeumannomyces graminis	58.07	3.00e-119	419.00
IUUC-Gga-040344	Gallus gallus	55.05	3.00e-93	333.00
IUUC-Gac-042256	Gasterosteus aculeatus	54.91	6.00e-93	332.00
IUUC-Gma-043226	Glycine max	52.57	3.00e-97	346.00
IUUC-Ggo-044523	Gorilla gorilla	50.30	2.00e-81	293.00
IUUC-Hsa-046659	Homo sapiens	55.18	5.00e-94	335.00
IUUC-Itr-048834	Ictidomys tridecemlineatus	55.18	4.00e-94	335.00
IUUC-Kpa-049139	Komagataella pastoris	55.97	1.00e-54	205.00
IUUC-Lch-049562	Latimeria chalumnae	55.05	2.00e-94	337.00
IUUC-Lpe-050737	Leersia perrieri	53.64	3.00e-99	353.00
IUUC-Loc-051798	Lepisosteus oculatus	54.24	2.00e-92	330.00
IUUC-Lma-052979	Leptosphaeria maculans	58.41	5.00e-113	399.00
IUUC-Laf-053391	Loxodonta africana	61.40	3.00e-71	259.00
IUUC-Mcc-055667	Macaca mulatta	55.18	5.00e-94	335.00
IUUC-Meu-056067	Macropus eugenii	68.97	1.00e-19	88.20
IUUC-Mor-057084	Magnaporthe oryzae	58.53	1.00e-120	424.00
IUUC-Mpo-057347	Magnaporthe poae	60.18	3.00e-121	426.00
IUUC-Mtr-057781	Medicago truncatula	54.30	4.00e-100	356.00
IUUC-Mla-059106	Melampsora laricipopulina	50.43	3.00e-99	353.00
IUUC-Mga-059473	Meleagris gallopavo	57.75	4.00e-84	302.00
IUUC-Mvi-060540	Microbotryum violaceum	50.14	3.00e-99	353.00
IUUC-Mmr-061138	Microcebus murinus	66.84	4.00e-66	242.00
IUUC-Mdo-062893	Monodelphis domestica	55.49	2.00e-94	336.00
IUUC-Mmu-063637	Mus musculus	55.18	5.00e-94	335.00
IUUC-Mac-064683	Musa acuminata	52.49	2.00e-99	353.00
IUUC-Mpu-066096	Mustela putorius furo	52.90	3.00e-78	283.00
IUUC-Mlu-067872	Myotis lucifugus	54.13	2.00e-90	323.00
IUUC-Nfi-068443	Neosartorya fischeri	98.50	0.00e+00	686.00
IUUC-Ncr-068953	Neurospora crassa	58.31	3.00e-115	406.00
IUUC-Nle-068972	Nomascus leucogenys	55.18	5.00e-94	335.00
IUUC-Opr-070215	Ochotona princeps	50.61	8.00e-80	288.00
IUUC-Ont-072538	Oreochromis niloticus	54.41	7.00e-93	332.00
IUUC-Oan-073143	Ornithorhynchus anatinus	55.49	3.00e-94	336.00
IUUC-Ocu-074197	Oryctolagus cuniculus	55.18	5.00e-94	335.00
IUUC-Oba-075884	Oryza barthii	50.14	1.00e-93	334.00
IUUC-Obr-076874	Oryza brachyantha	54.07	1.00e-98	351.00
IUUC-Ogl-077169	Oryza glaberrima	54.09	6.00e-98	348.00
IUUC-Ogu-078258	Oryza glumaepatula	54.09	6.00e-98	348.00
IUUC-Oin-079101	Oryza indica	50.41	7.00e-94	335.00
IUUC-Olo-080708	Oryza longistaminata	50.35	6.00e-70	255.00
IUUC-Ome-081571	Oryza meridionalis	50.41	7.00e-94	335.00
IUUC-Oni-082888	Oryza nivara	50.41	7.00e-94	335.00
IUUC-Opu-083182	Oryza punctata	54.09	6.00e-98	348.00
IUUC-Oru-084895	Oryza rufipogon	50.41	7.00e-94	335.00
IUUC-Osa-085331	Oryza sativa	54.09	6.00e-98	348.00
IUUC-Ola-086850	Oryzias latipes	54.74	3.00e-93	333.00
IUUC-Olu-087607	Ostreococcus lucimarinus	60.16	2.00e-87	313.00
IUUC-Oga-088640	Otolemur garnettii	55.05	2.00e-93	334.00
IUUC-Oar-090299	Ovis aries	55.05	2.00e-93	333.00
IUUC-Ptr-091499	Pan troglodytes	55.18	5.00e-94	335.00
IUUC-Pan-091751	Papio anubis	57.75	1.00e-83	301.00
IUUC-Psi-092978	Pelodiscus sinensis	54.74	7.00e-93	332.00
IUUC-Pma-094634	Petromyzon marinus	55.49	2.00e-94	337.00
IUUC-Pno-095094	Phaeosphaeria nodorum	59.15	1.00e-113	400.00
IUUC-Ppa-095440	Physcomitrella patens	54.19	9.00e-103	365.00
IUUC-Pfo-097332	Poecilia formosa	54.74	9.00e-93	331.00
IUUC-Pab-097998	Pongo abelii	55.18	5.00e-94	335.00
IUUC-Pop-098905	Populus trichocarpa	52.31	6.00e-103	365.00
IUUC-Ppe-101309	Prunus persica	53.74	2.00e-106	377.00
IUUC-Pva-102953	Pteropus vampyrus	55.18	5.00e-94	335.00
IUUC-Pgr-103452	Puccinia graminis	60.53	1.00e-92	331.00
IUUC-Ptt-103777	Puccinia triticina	60.80	4.00e-89	319.00
IUUC-Pte-104273	Pyrenophora teres	57.44	6.00e-113	398.00
IUUC-Pyt-104627	Pyrenophora triticirepentis	58.48	6.00e-113	398.00
IUUC-Rno-105666	Rattus norvegicus	55.35	2.00e-93	334.00
IUUC-Sce-106319	Saccharomyces cerevisiae	39.42	3.00e-38	150.00
IUUC-Sha-106602	Sarcophilus harrisii	55.49	2.00e-94	336.00
IUUC-Sja-107822	Schizosaccharomyces japonicus	43.11	7.00e-47	178.00
IUUC-Spo-108318	Schizosaccharomyces pombe	42.97	5.00e-62	229.00
IUUC-Ssl-108428	Sclerotinia sclerotiorum	65.86	1.00e-130	457.00
IUUC-Smo-108821	Selaginella moellendorffii	55.06	9.00e-103	364.00
IUUC-Sit-110526	Setaria italica	53.45	8.00e-93	332.00
IUUC-Sly-110851	Solanum lycopersicum	53.64	5.00e-106	375.00
IUUC-Stu-112151	Solanum tuberosum	53.64	4.00e-106	375.00
IUUC-Sar-113459	Sorex araneus	55.18	5.00e-94	335.00
IUUC-Sbi-114873	Sorghum bicolor	54.35	4.00e-97	346.00
IUUC-Sre-114919	Sporisorium reilianum	61.57	3.00e-91	326.00
IUUC-Ssc-116102	Sus scrofa	55.18	5.00e-94	335.00
IUUC-Tgu-116937	Taeniopygia guttata	65.50	1.00e-79	287.00
IUUC-Tru-118615	Takifugu rubripes	54.55	2.00e-93	333.00
IUUC-Tsy-119173	Tarsius syrichta	61.40	8.00e-90	321.00
IUUC-Tni-120246	Tetraodon nigroviridis	54.55	2.00e-93	333.00
IUUC-Tca-121859	Theobroma cacao	54.68	4.00e-104	369.00
IUUC-Tre-122030	Trichoderma reesei	59.64	1.00e-119	420.00
IUUC-Tvi-122506	Trichoderma virens	60.06	4.00e-119	419.00
IUUC-Tae-125382	Triticum aestivum	54.95	2.00e-97	347.00
IUUC-Tur-126517	Triticum urartu	56.09	6.00e-96	342.00
IUUC-Tme-127122	Tuber melanosporum	58.53	5.00e-117	412.00
IUUC-Tbe-128108	Tupaia belangeri	55.05	3.00e-91	326.00
IUUC-Ttr-128644	Tursiops truncatus	55.18	5.00e-94	335.00
IUUC-Uma-129390	Ustilago maydis	59.30	4.00e-91	326.00
IUUC-Vda-129932	Verticillium dahliae	57.51	3.00e-116	409.00
IUUC-Vpa-130110	Vicugna pacos	55.18	5.00e-94	335.00
IUUC-Vvi-131534	Vitis vinifera	52.80	5.00e-101	358.00
IUUC-Xtr-132739	Xenopus tropicalis	54.27	4.00e-94	336.00
IUUC-Xma-133919	Xiphophorus maculatus	54.74	9.00e-93	331.00
IUUC-Yli-134677	Yarrowia lipolytica	52.44	1.00e-103	367.00
IUUC-Zma-135578	Zea mays	52.92	3.00e-96	343.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence