iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071936

Ensembl Protein ID

ENSONIP00000013466.1

UniProt Accession

I3JX71; I3JX71_ORENI

Genbank Protein ID

ENSONIP00000013466

Protein Name

Probable cytosolic iron-sulfur protein assembly protein CIAO1; WD repeat-containing protein 39

Genbank Nucleotide ID

AERX01013636

Gene Name

ciao1; CIAO1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000010711.1	ENSONIT00000013476.1	ENSONIP00000013466.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-43	144.7	103	135
UBD/Beta-Prp	3.30e-83	279.7	55	245

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gH+++v c+a+ ++ +ll+++s+D+++ vW+++
   Q: 103  GHENEVKCVAWaPSgNLLATCSRDKSVWVWEVD 135
           8***********666****************86 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdls...tgkcv 87
           +l++ h+  +++v++sp +++la++s d+t+ +w+ ++ ++  l  l+ghe+ev++v + p+g++l+t+s+D+ + vw+++    ++cv
   Q: 55   VLQDGHQRTVRKVAWSPCGNYLASASFDATTCIWKKKNDDFesLTVLEGHENEVKCVAWAPSGNLLATCSRDKSVWVWEVDeedEYECV 143
           578889999999**************************999988999*******************************8777779**** PP
   S: 88   htlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl........k 167
            +++ h+++v  + ++p+++ l+s+s d+ i +++ e + +    tl+gh+++v++++++  g+ l+s+s+Drtv++W+          
   Q: 144  TVVNSHTQDVKHVVWHPTQELLASASYDNNICLYKEEDDDWECRaTLQGHTSTVWSLCFDAAGQRLASCSDDRTVKIWREypaesgpdL 232
           **********************************99887665545*********************************99999999999 PP
   S: 168  tgkllrtltgght 180
           + k++ tl+g+h 
   Q: 233  SWKCVCTLSGYHG 245
           9999999999986 PP

Organism

Oreochromis niloticus

Functional Description
(View)

Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins.

Protein Sequence
(Fasta)

MKEALSLVQR LSAHPDSRCW FVSWSPNGTL LASCGGDKTI RIWGKEGDSW ICKNVLQDGH 60
QRTVRKVAWS PCGNYLASAS FDATTCIWKK KNDDFESLTV LEGHENEVKC VAWAPSGNLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGGAGG CTCTGTCCCT GGTTCAGAGG TTGAGCGCAC ACCCGGACTC CCGCTGCTGG 60
TTCGTCAGCT GGAGCCCCAA CGGGACGCTG CTGGCCTCAT GTGGGGGCGA CAAGACCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR028608--CIAO1/Cia1
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097361--C:CIA complex
GO:0016226--P:iron-sulfur cluster assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000874	Aegilops tauschii	47.96	5.00e-67	249.00
IUUC-Aml-001317	Ailuropoda melanoleuca	75.37	1.00e-142	499.00
IUUC-Atr-003029	Amborella trichopoda	49.85	2.00e-88	318.00
IUUC-Apl-004042	Anas platyrhynchos	59.09	1.00e-39	154.00
IUUC-Aly-006458	Arabidopsis lyrata	48.99	5.00e-86	311.00
IUUC-Ath-006671	Arabidopsis thaliana	48.99	9.00e-86	310.00
IUUC-Ago-007820	Ashbya gossypii	42.39	4.00e-61	228.00
IUUC-Acl-008042	Aspergillus clavatus	34.57	4.00e-45	175.00
IUUC-Afl-008639	Aspergillus flavus	31.03	4.00e-50	192.00
IUUC-Afu-008899	Aspergillus fumigatus	29.91	5.00e-46	179.00
IUUC-Ani-009453	Aspergillus nidulans	30.32	2.00e-47	183.00
IUUC-Ang-009758	Aspergillus niger	39.04	4.00e-42	165.00
IUUC-Aor-010212	Aspergillus oryzae	31.03	4.00e-50	192.00
IUUC-Ate-010314	Aspergillus terreus	30.94	6.00e-48	185.00
IUUC-Ame-010676	Astyanax mexicanus	80.48	7.00e-162	563.00
IUUC-Bgr-012095	Blumeria graminis	28.94	3.00e-34	139.00
IUUC-Bta-012884	Bos taurus	75.67	2.00e-142	498.00
IUUC-Bci-013622	Botrytis cinerea	31.12	2.00e-34	139.00
IUUC-Bdi-014614	Brachypodium distachyon	47.45	4.00e-84	305.00
IUUC-Bol-016439	Brassica oleracea	48.05	5.00e-82	297.00
IUUC-Bra-016830	Brassica rapa	46.33	1.00e-80	293.00
IUUC-Cel-018709	Caenorhabditis elegans	41.30	1.00e-64	239.00
IUUC-Cja-019822	Callithrix jacchus	75.37	7.00e-142	496.00
IUUC-Cfa-020823	Canis familiaris	75.37	3.00e-143	501.00
IUUC-Cre-022811	Chlamydomonas reinhardtii	47.28	4.00e-81	294.00
IUUC-Csa-023754	Chlorocebus sabaeus	75.67	9.00e-143	499.00
IUUC-Cin-025395	Ciona intestinalis	57.31	1.00e-111	395.00
IUUC-Csv-025943	Ciona savignyi	54.95	1.00e-106	379.00
IUUC-Cgl-026435	Colletotrichum gloeosporioides	29.18	2.00e-31	130.00
IUUC-Cne-026939	Cryptococcus neoformans	30.59	4.00e-45	175.00
IUUC-Cme-027239	Cyanidioschyzon merolae	41.35	1.00e-41	164.00
IUUC-Dre-028172	Danio rerio	80.18	2.00e-160	558.00
IUUC-Dno-029472	Dasypus novemcinctus	75.26	3.00e-118	417.00
IUUC-Dor-031134	Dipodomys ordii	64.99	4.00e-115	407.00
IUUC-Dse-031535	Dothistroma septosporum	28.44	6.00e-42	165.00
IUUC-Dme-032020	Drosophila melanogaster	59.46	4.00e-114	404.00
IUUC-Eca-033700	Equus caballus	75.96	8.00e-144	503.00
IUUC-Eeu-035010	Erinaceus europaeus	73.29	3.00e-137	481.00
IUUC-Fca-036309	Felis catus	68.05	1.00e-133	469.00
IUUC-Fal-037243	Ficedula albicollis	66.51	9.00e-76	276.00
IUUC-Fox-038058	Fusarium oxysporum	33.22	8.00e-36	145.00
IUUC-Fso-038459	Fusarium solani	31.35	6.00e-34	138.00
IUUC-Gmo-039375	Gadus morhua	80.79	2.00e-150	525.00
IUUC-Gga-040294	Gallus gallus	70.61	9.00e-106	376.00
IUUC-Gac-042499	Gasterosteus aculeatus	88.06	4.00e-162	563.00
IUUC-Gma-043543	Glycine max	47.20	6.00e-87	314.00
IUUC-Ggo-045181	Gorilla gorilla	75.67	9.00e-143	499.00
IUUC-Hsa-046528	Homo sapiens	75.67	9.00e-143	499.00
IUUC-Hvu-047341	Hordeum vulgare	54.92	4.00e-55	207.00
IUUC-Itr-048790	Ictidomys tridecemlineatus	76.26	2.00e-143	501.00
IUUC-Kpa-049353	Komagataella pastoris	35.67	1.00e-52	200.00
IUUC-Lch-049763	Latimeria chalumnae	72.70	2.00e-143	501.00
IUUC-Lpe-051500	Leersia perrieri	42.82	3.00e-81	295.00
IUUC-Loc-052021	Lepisosteus oculatus	75.89	1.00e-143	502.00
IUUC-Lma-053331	Leptosphaeria maculans	31.34	2.00e-49	191.00
IUUC-Laf-054558	Loxodonta africana	74.18	1.00e-140	492.00
IUUC-Mcc-055374	Macaca mulatta	75.37	6.00e-143	499.00
IUUC-Meu-056042	Macropus eugenii	63.32	2.00e-86	311.00
IUUC-Mor-057187	Magnaporthe oryzae	29.36	5.00e-35	142.00
IUUC-Mtr-058072	Medicago truncatula	48.66	3.00e-87	315.00
IUUC-Mla-059108	Melampsora laricipopulina	31.98	4.00e-51	195.00
IUUC-Mga-059370	Meleagris gallopavo	55.36	3.00e-83	301.00
IUUC-Mvi-060495	Microbotryum violaceum	36.56	7.00e-55	207.00
IUUC-Mmr-060902	Microcebus murinus	75.96	7.00e-143	499.00
IUUC-Mdo-062510	Monodelphis domestica	74.78	3.00e-137	481.00
IUUC-Mmu-063575	Mus musculus	75.22	2.00e-140	491.00
IUUC-Mac-065322	Musa acuminata	50.00	2.00e-91	329.00
IUUC-Mpu-065925	Mustela putorius furo	75.07	3.00e-143	501.00
IUUC-Mlu-067755	Myotis lucifugus	74.48	7.00e-141	493.00
IUUC-Nfi-068327	Neosartorya fischeri	29.86	3.00e-45	176.00
IUUC-Ncr-068845	Neurospora crassa	30.12	1.00e-25	110.00
IUUC-Nle-069406	Nomascus leucogenys	74.48	6.00e-138	483.00
IUUC-Opr-070416	Ochotona princeps	84.66	3.00e-69	255.00
IUUC-Oan-073452	Ornithorhynchus anatinus	73.33	9.00e-55	205.00
IUUC-Ocu-074791	Oryctolagus cuniculus	75.07	1.00e-141	495.00
IUUC-Oba-075636	Oryza barthii	47.35	2.00e-87	316.00
IUUC-Obr-076742	Oryza brachyantha	48.77	3.00e-77	281.00
IUUC-Ogl-077766	Oryza glaberrima	47.35	2.00e-87	316.00
IUUC-Ogu-079039	Oryza glumaepatula	47.35	5.00e-88	317.00
IUUC-Oin-079315	Oryza indica	47.93	5.00e-77	281.00
IUUC-Olo-080669	Oryza longistaminata	41.86	5.00e-80	291.00
IUUC-Ome-081490	Oryza meridionalis	47.35	7.00e-88	317.00
IUUC-Oni-082572	Oryza nivara	47.35	2.00e-87	316.00
IUUC-Opu-083732	Oryza punctata	47.65	2.00e-88	319.00
IUUC-Oru-084763	Oryza rufipogon	47.35	2.00e-87	316.00
IUUC-Osa-085372	Oryza sativa	47.35	2.00e-87	316.00
IUUC-Ola-087379	Oryzias latipes	87.80	1.00e-163	568.00
IUUC-Olu-087801	Ostreococcus lucimarinus	35.69	5.00e-41	161.00
IUUC-Oga-089076	Otolemur garnettii	76.56	7.00e-145	506.00
IUUC-Oar-090022	Ovis aries	75.67	5.00e-144	503.00
IUUC-Ptr-090809	Pan troglodytes	75.67	9.00e-143	499.00
IUUC-Pan-091685	Papio anubis	75.67	2.00e-144	506.00
IUUC-Psi-093046	Pelodiscus sinensis	72.40	3.00e-138	484.00
IUUC-Pma-094181	Petromyzon marinus	63.02	2.00e-127	448.00
IUUC-Pno-094882	Phaeosphaeria nodorum	31.57	8.00e-51	194.00
IUUC-Ppa-095172	Physcomitrella patens	47.51	5.00e-85	307.00
IUUC-Pfo-096396	Poecilia formosa	90.03	7.00e-169	586.00
IUUC-Pab-098427	Pongo abelii	75.37	8.00e-141	493.00
IUUC-Pop-100016	Populus trichocarpa	50.89	2.00e-91	329.00
IUUC-Pca-101048	Procavia capensis	75.07	5.00e-141	493.00
IUUC-Ppe-102050	Prunus persica	45.53	3.00e-84	305.00
IUUC-Pva-103117	Pteropus vampyrus	75.67	3.00e-142	498.00
IUUC-Pgr-103307	Puccinia graminis	34.55	1.00e-55	210.00
IUUC-Ptt-103938	Puccinia triticina	38.41	7.00e-47	181.00
IUUC-Pte-104315	Pyrenophora teres	31.67	1.00e-51	197.00
IUUC-Pyt-104825	Pyrenophora triticirepentis	31.67	1.00e-51	197.00
IUUC-Rno-105523	Rattus norvegicus	76.42	6.00e-142	496.00
IUUC-Sce-106297	Saccharomyces cerevisiae	38.76	4.00e-60	224.00
IUUC-Sha-106981	Sarcophilus harrisii	75.60	9.00e-115	406.00
IUUC-Sja-107715	Schizosaccharomyces japonicus	37.06	1.00e-51	197.00
IUUC-Spo-108214	Schizosaccharomyces pombe	40.66	2.00e-58	220.00
IUUC-Smo-109034	Selaginella moellendorffii	46.09	3.00e-83	302.00
IUUC-Sit-110663	Setaria italica	47.63	1.00e-88	319.00
IUUC-Sly-110898	Solanum lycopersicum	48.36	1.00e-81	296.00
IUUC-Stu-112647	Solanum tuberosum	51.89	7.00e-71	260.00
IUUC-Sbi-114288	Sorghum bicolor	46.76	4.00e-86	311.00
IUUC-Sre-115065	Sporisorium reilianum	40.43	2.00e-65	243.00
IUUC-Ssc-115960	Sus scrofa	70.62	3.00e-143	501.00
IUUC-Tru-118382	Takifugu rubripes	85.03	2.00e-169	587.00
IUUC-Tsy-119585	Tarsius syrichta	67.36	2.00e-121	429.00
IUUC-Tni-120133	Tetraodon nigroviridis	84.64	5.00e-160	556.00
IUUC-Tca-121167	Theobroma cacao	48.38	2.00e-80	292.00
IUUC-Tre-122119	Trichoderma reesei	27.75	3.00e-34	139.00
IUUC-Tvi-122407	Trichoderma virens	33.33	6.00e-40	158.00
IUUC-Tae-125748	Triticum aestivum	47.06	4.00e-83	301.00
IUUC-Tur-126682	Triticum urartu	48.30	6.00e-68	250.00
IUUC-Tme-127095	Tuber melanosporum	34.73	3.00e-58	219.00
IUUC-Tbe-128004	Tupaia belangeri	75.67	3.00e-142	497.00
IUUC-Ttr-129284	Tursiops truncatus	73.53	2.00e-136	478.00
IUUC-Uma-129527	Ustilago maydis	40.80	1.00e-65	244.00
IUUC-Vda-129854	Verticillium dahliae	28.40	6.00e-33	135.00
IUUC-Vpa-130681	Vicugna pacos	90.52	3.00e-46	178.00
IUUC-Vvi-131004	Vitis vinifera	50.89	3.00e-86	311.00
IUUC-Xtr-131928	Xenopus tropicalis	73.27	5.00e-137	480.00
IUUC-Xma-134290	Xiphophorus maculatus	87.92	9.00e-164	569.00
IUUC-Yli-134364	Yarrowia lipolytica	41.86	1.00e-62	233.00
IUUC-Zma-135658	Zea mays	47.06	1.00e-85	310.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence