iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cgl-026510

Ensembl Protein ID

ELA26383

UniProt Accession

L2FKY5; L2FKY5_COLGN

Genbank Protein ID

ELA26383.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

KB021057

Gene Name

CGGC5_12647

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CGGC5_12647	ELA26383	ELA26383

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.80e-34	113.9	56	92
UBD/Beta-Prp	8.70e-77	257.9	9	334

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f  + +l+vsG+dD +ikvW++ t ++l
   Q: 56   HDGPVRGIDFhKTqPLFVSGGDDYKIKVWSYQTRRCL 92
           99*********4459***************9999887 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
           t +++++s+ + ++f+p++++++++  ++ti++wd+++g+l+ ++++h+++v+ ++f+++++++v+g++D+ ikvw+++t+ c+ tl+gh d+v+++ f+ 
   Q: 9    TKFESKSSRAKGIAFHPKRPWILVALHSSTIQLWDYRMGTLIDRFEEHDGPVRGIDFHKTQPLFVSGGDDYKIKVWSYQTRRCLFTLNGHLDYVRTVFFHH 109
           67889999********************************************************************************************* PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...............................ktgkllrt 174
           +  +++s+s+d+tir+w++++++ +  t +gh++  +c+++hp+++l+vs+slD+ vr+Wd+                               +t+ +++ 
   Q: 110  ELPWILSASDDQTIRIWNWQNRSLIC-TMTGHNHYAMCAQFHPKEDLVVSASLDQSVRVWDIsglrkkhsaptsmtfedqvaranqnqtdmfgNTDAVVKF 209
           *************************9.********************************************************999999999777777776 PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavl 273
             +gh++ v++++f+++++ +vs+++d+ vklw +++++   v+t++gh +n +   f+p++++++s+++D++ir+Wdl +++ +++++++n++++ +a+ 
   Q: 210  VLEGHDRGVNWVAFHPTMPLIVSAGDDRLVKLWRMSETKAweVDTCRGHFQNASGCLFHPHQDLILSVGEDKTIRVWDLNKRTAVQSFKRENDRFWVIAA- 309
           6777********************************888778**********************************************************. PP
   S: 274  sfgdnvlvlgsedskvniwklkknep 299
           +++ n +++g  d+ v+++kl++++p
   Q: 310  HPEINLFAAG-HDNGVMVFKLERERP 334
           6666555555.478*******98775 PP

Organism

Colletotrichum gloeosporioides

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MQASSGMLTK FESKSSRAKG IAFHPKRPWI LVALHSSTIQ LWDYRMGTLI DRFEEHDGPV 60
RGIDFHKTQP LFVSGGDDYK IKVWSYQTRR CLFTLNGHLD YVRTVFFHHE LPWILSASDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGGCCT CCTCGGGCAT GTTGACCAAG GTATGTCTGC CCACGGCGCA TTGGCATCCA 60
CTCGAGATCC CTTGAGGATA TACTCGATGG CTCACAATCA ATTCAGTTCG AGTCCAAGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011044--Quino_amine_DH_bsu
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	55.86	0.00e+00	986.00
IUUC-Aml-001758	Ailuropoda melanoleuca	48.80	0.00e+00	1209.00
IUUC-Atr-002493	Amborella trichopoda	55.72	0.00e+00	967.00
IUUC-Apl-003385	Anas platyrhynchos	43.20	0.00e+00	891.00
IUUC-Aca-005154	Anolis carolinensis	73.79	3.00e-94	335.00
IUUC-Aly-006020	Arabidopsis lyrata	54.51	0.00e+00	958.00
IUUC-Ath-007360	Arabidopsis thaliana	54.99	0.00e+00	967.00
IUUC-Ago-007992	Ashbya gossypii	51.24	0.00e+00	1233.00
IUUC-Acl-008027	Aspergillus clavatus	77.25	0.00e+00	1935.00
IUUC-Afl-008644	Aspergillus flavus	77.82	0.00e+00	1952.00
IUUC-Afu-008964	Aspergillus fumigatus	78.65	0.00e+00	1980.00
IUUC-Ani-009379	Aspergillus nidulans	84.17	0.00e+00	1531.00
IUUC-Ang-009756	Aspergillus niger	78.71	0.00e+00	1956.00
IUUC-Aor-010174	Aspergillus oryzae	77.74	0.00e+00	1947.00
IUUC-Ate-010302	Aspergillus terreus	77.23	0.00e+00	1982.00
IUUC-Ame-011229	Astyanax mexicanus	57.57	0.00e+00	1016.00
IUUC-Bgr-012300	Blumeria graminis	78.84	0.00e+00	1971.00
IUUC-Bta-012524	Bos taurus	49.15	0.00e+00	1202.00
IUUC-Bci-013781	Botrytis cinerea	84.99	0.00e+00	2119.00
IUUC-Bdi-014549	Brachypodium distachyon	46.30	0.00e+00	1120.00
IUUC-Bol-015925	Brassica oleracea	55.23	0.00e+00	964.00
IUUC-Bra-016978	Brassica rapa	54.87	0.00e+00	959.00
IUUC-Cel-018115	Caenorhabditis elegans	52.44	0.00e+00	903.00
IUUC-Cja-019107	Callithrix jacchus	47.63	0.00e+00	1183.00
IUUC-Cfa-020675	Canis familiaris	48.49	0.00e+00	1180.00
IUUC-Cpo-021813	Cavia porcellus	49.07	0.00e+00	1219.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	56.73	0.00e+00	1000.00
IUUC-Csa-023523	Chlorocebus sabaeus	48.74	0.00e+00	1219.00
IUUC-Cho-024704	Choloepus hoffmanni	63.90	3.00e-122	431.00
IUUC-Cin-025572	Ciona intestinalis	47.18	0.00e+00	1168.00
IUUC-Csv-025864	Ciona savignyi	55.00	0.00e+00	955.00
IUUC-Cne-027053	Cryptococcus neoformans	55.76	0.00e+00	1337.00
IUUC-Cme-027222	Cyanidioschyzon merolae	38.47	2.00e-138	485.00
IUUC-Dre-027421	Danio rerio	49.31	0.00e+00	1212.00
IUUC-Dno-029303	Dasypus novemcinctus	48.95	0.00e+00	1215.00
IUUC-Dor-030290	Dipodomys ordii	47.02	5.00e-147	513.00
IUUC-Dse-031543	Dothistroma septosporum	75.47	0.00e+00	1845.00
IUUC-Dme-031945	Drosophila melanogaster	56.37	0.00e+00	962.00
IUUC-Ete-032873	Echinops telfairi	47.41	0.00e+00	1063.00
IUUC-Eca-033773	Equus caballus	48.18	0.00e+00	1172.00
IUUC-Eeu-034874	Erinaceus europaeus	36.27	3.00e-162	564.00
IUUC-Fca-035739	Felis catus	57.04	0.00e+00	1008.00
IUUC-Fal-037263	Ficedula albicollis	53.12	0.00e+00	886.00
IUUC-Fox-037738	Fusarium oxysporum	88.21	0.00e+00	2237.00
IUUC-Fso-038153	Fusarium solani	88.45	0.00e+00	2241.00
IUUC-Gmo-039602	Gadus morhua	46.61	0.00e+00	1117.00
IUUC-Ggr-039931	Gaeumannomyces graminis	87.28	0.00e+00	2134.00
IUUC-Gga-040590	Gallus gallus	48.29	0.00e+00	1208.00
IUUC-Gac-041318	Gasterosteus aculeatus	47.63	0.00e+00	1182.00
IUUC-Gma-043894	Glycine max	46.79	0.00e+00	1132.00
IUUC-Ggo-045029	Gorilla gorilla	48.39	0.00e+00	1208.00
IUUC-Hsa-046078	Homo sapiens	48.39	0.00e+00	1210.00
IUUC-Hvu-047556	Hordeum vulgare	46.26	0.00e+00	1121.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	39.89	0.00e+00	646.00
IUUC-Kpa-049256	Komagataella pastoris	54.02	0.00e+00	1353.00
IUUC-Lch-049706	Latimeria chalumnae	56.92	0.00e+00	1010.00
IUUC-Lpe-051316	Leersia perrieri	55.58	0.00e+00	976.00
IUUC-Loc-051867	Lepisosteus oculatus	46.63	0.00e+00	759.00
IUUC-Lma-053138	Leptosphaeria maculans	76.30	0.00e+00	1934.00
IUUC-Laf-053510	Loxodonta africana	48.94	0.00e+00	1216.00
IUUC-Mcc-055836	Macaca mulatta	48.71	0.00e+00	1210.00
IUUC-Meu-056238	Macropus eugenii	52.06	0.00e+00	711.00
IUUC-Mor-057172	Magnaporthe oryzae	88.77	0.00e+00	2243.00
IUUC-Mpo-057300	Magnaporthe poae	86.79	0.00e+00	2141.00
IUUC-Mtr-058248	Medicago truncatula	46.79	0.00e+00	1137.00
IUUC-Mla-059019	Melampsora laricipopulina	56.77	0.00e+00	1400.00
IUUC-Mga-059499	Meleagris gallopavo	48.29	0.00e+00	1205.00
IUUC-Mvi-060336	Microbotryum violaceum	55.57	0.00e+00	1390.00
IUUC-Mmr-061102	Microcebus murinus	48.76	0.00e+00	1201.00
IUUC-Mdo-062594	Monodelphis domestica	49.07	0.00e+00	1224.00
IUUC-Mmu-063736	Mus musculus	48.75	0.00e+00	1206.00
IUUC-Mac-065398	Musa acuminata	44.34	0.00e+00	1024.00
IUUC-Mpu-066701	Mustela putorius furo	48.02	0.00e+00	1206.00
IUUC-Mlu-067392	Myotis lucifugus	49.27	0.00e+00	1211.00
IUUC-Nfi-068270	Neosartorya fischeri	77.99	0.00e+00	1954.00
IUUC-Ncr-068892	Neurospora crassa	87.34	0.00e+00	2175.00
IUUC-Nle-069634	Nomascus leucogenys	60.45	0.00e+00	874.00
IUUC-Opr-070952	Ochotona princeps	36.56	3.00e-163	567.00
IUUC-Ont-072488	Oreochromis niloticus	47.84	0.00e+00	1186.00
IUUC-Ocu-074211	Oryctolagus cuniculus	48.91	0.00e+00	1211.00
IUUC-Oba-075761	Oryza barthii	55.70	0.00e+00	979.00
IUUC-Obr-076429	Oryza brachyantha	55.70	0.00e+00	978.00
IUUC-Ogl-077364	Oryza glaberrima	55.70	0.00e+00	979.00
IUUC-Ogu-078257	Oryza glumaepatula	55.58	0.00e+00	975.00
IUUC-Oin-079274	Oryza indica	55.58	0.00e+00	977.00
IUUC-Olo-080895	Oryza longistaminata	55.85	0.00e+00	969.00
IUUC-Ome-081993	Oryza meridionalis	57.96	0.00e+00	936.00
IUUC-Oni-082874	Oryza nivara	55.70	0.00e+00	978.00
IUUC-Opu-083885	Oryza punctata	55.70	0.00e+00	978.00
IUUC-Oru-084274	Oryza rufipogon	55.58	0.00e+00	976.00
IUUC-Osa-085565	Oryza sativa	55.58	0.00e+00	976.00
IUUC-Ola-086921	Oryzias latipes	48.15	0.00e+00	1179.00
IUUC-Olu-087639	Ostreococcus lucimarinus	48.35	0.00e+00	1166.00
IUUC-Oga-087991	Otolemur garnettii	46.60	0.00e+00	1140.00
IUUC-Oar-089590	Ovis aries	49.23	0.00e+00	1216.00
IUUC-Ptr-090808	Pan troglodytes	48.39	0.00e+00	1209.00
IUUC-Pan-092475	Papio anubis	48.38	0.00e+00	1206.00
IUUC-Psi-093044	Pelodiscus sinensis	53.03	0.00e+00	852.00
IUUC-Pno-094839	Phaeosphaeria nodorum	75.38	0.00e+00	1855.00
IUUC-Ppa-095254	Physcomitrella patens	50.29	0.00e+00	1206.00
IUUC-Pfo-097493	Poecilia formosa	49.06	0.00e+00	1186.00
IUUC-Pab-098497	Pongo abelii	48.66	0.00e+00	1218.00
IUUC-Pop-099992	Populus trichocarpa	56.25	0.00e+00	972.00
IUUC-Pca-100413	Procavia capensis	53.94	0.00e+00	626.00
IUUC-Ppe-101899	Prunus persica	55.72	0.00e+00	977.00
IUUC-Pva-102126	Pteropus vampyrus	47.19	0.00e+00	1149.00
IUUC-Pgr-103376	Puccinia graminis	56.39	0.00e+00	1415.00
IUUC-Ptt-103978	Puccinia triticina	50.84	0.00e+00	1198.00
IUUC-Pte-104126	Pyrenophora teres	84.50	0.00e+00	1510.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	67.01	0.00e+00	1418.00
IUUC-Rno-105428	Rattus norvegicus	49.31	0.00e+00	1219.00
IUUC-Sce-106464	Saccharomyces cerevisiae	50.54	0.00e+00	1203.00
IUUC-Sha-107301	Sarcophilus harrisii	48.66	0.00e+00	1190.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	52.55	0.00e+00	1340.00
IUUC-Spo-108217	Schizosaccharomyces pombe	55.45	0.00e+00	1412.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	84.81	0.00e+00	2119.00
IUUC-Smo-109582	Selaginella moellendorffii	57.28	0.00e+00	1007.00
IUUC-Sit-109697	Setaria italica	55.14	0.00e+00	976.00
IUUC-Sly-111759	Solanum lycopersicum	55.32	0.00e+00	982.00
IUUC-Stu-112564	Solanum tuberosum	55.20	0.00e+00	983.00
IUUC-Sar-113313	Sorex araneus	36.38	1.00e-157	548.00
IUUC-Sbi-114388	Sorghum bicolor	55.14	0.00e+00	976.00
IUUC-Sre-115209	Sporisorium reilianum	63.11	0.00e+00	1133.00
IUUC-Ssc-115933	Sus scrofa	49.15	0.00e+00	1214.00
IUUC-Tgu-117109	Taeniopygia guttata	42.42	2.00e-88	318.00
IUUC-Tru-117772	Takifugu rubripes	48.51	0.00e+00	1167.00
IUUC-Tsy-119105	Tarsius syrichta	51.70	0.00e+00	890.00
IUUC-Tni-120556	Tetraodon nigroviridis	40.81	5.00e-169	586.00
IUUC-Tca-120918	Theobroma cacao	56.42	0.00e+00	978.00
IUUC-Tre-121951	Trichoderma reesei	86.48	0.00e+00	2128.00
IUUC-Tvi-122359	Trichoderma virens	86.23	0.00e+00	2166.00
IUUC-Tae-125527	Triticum aestivum	55.86	0.00e+00	986.00
IUUC-Tur-126754	Triticum urartu	55.74	0.00e+00	985.00
IUUC-Tme-127170	Tuber melanosporum	76.10	0.00e+00	1966.00
IUUC-Tbe-127882	Tupaia belangeri	64.10	2.00e-122	432.00
IUUC-Ttr-128217	Tursiops truncatus	47.19	0.00e+00	1144.00
IUUC-Uma-129337	Ustilago maydis	62.63	0.00e+00	1129.00
IUUC-Vda-129828	Verticillium dahliae	86.98	0.00e+00	2155.00
IUUC-Vpa-130537	Vicugna pacos	48.51	0.00e+00	1192.00
IUUC-Vvi-130958	Vitis vinifera	56.20	0.00e+00	984.00
IUUC-Xtr-132857	Xenopus tropicalis	46.89	0.00e+00	1121.00
IUUC-Xma-133138	Xiphophorus maculatus	49.23	0.00e+00	1191.00
IUUC-Yli-134399	Yarrowia lipolytica	61.72	0.00e+00	1098.00
IUUC-Zma-135612	Zea mays	46.21	0.00e+00	1123.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence