iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-044770

Ensembl Protein ID

ENSGGOP00000026662.1

UniProt Accession

G3SEX8; G3SEX8_GORGO

Protein Name

Non-specific serine/threonine protein kinase

Gene Name

MARK4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000008801.2	ENSGGOT00000029347.1	ENSGGOP00000026662.1
ENSGGOG00000008801.2	ENSGGOT00000008842.2	ENSGGOP00000008607.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	95.80	0.00e+00	1222.00	IUUC-Hsa-045897

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

LDSSCSISPA QHGTLGSGRS SDKGPSWSSR SLGARCRNSI ASCPEEQPHV GNYRLLRTIG 60
KGNFAKVKLA RHILTGREVA IKIIDKTQLN PSSLQKLFRE VRIMKGLNHP NIVKLFEVIE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGGATAGCT CATGCTCCAT CTCCCCCGCC CAGCATGGCA CCTTGGGCAG TGGCCGCTCC 60
TCGGACAAAG GCCCGTCCTG GTCCAGCCGC TCACTGGGTG CCCGTTGCCG GAACTCCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR028375--KA1/Ssp2_C
IPR001772--KA1_dom
IPR011009--Kinase-like_dom
IPR033624--MARK/par1
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA

PROSITE

PS50032--KA1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF02149--KA1
PF00069--Pkinase
PF00627--UBA

SMART

SM00220--S_TKc
SM00165--UBA

Gene Ontology

GO:0005813--C:centrosome
GO:0036064--C:ciliary basal body
GO:0043005--C:neuron projection
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0050321--F:tau-protein kinase activity
GO:0030010--P:establishment of cell polarity
GO:0001578--P:microtubule bundle formation
GO:0007399--P:nervous system development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001559	Ailuropoda melanoleuca	54.27	0.00e+00	727.00
IUUC-Aca-004735	Anolis carolinensis	54.61	0.00e+00	780.00
IUUC-Ame-011854	Astyanax mexicanus	57.12	3.00e-174	605.00
IUUC-Bta-013546	Bos taurus	93.95	0.00e+00	1236.00
IUUC-Cel-018198	Caenorhabditis elegans	68.60	4.00e-153	536.00
IUUC-Cja-019522	Callithrix jacchus	95.53	0.00e+00	1248.00
IUUC-Cfa-020231	Canis familiaris	94.42	0.00e+00	1242.00
IUUC-Cpo-022532	Cavia porcellus	93.76	0.00e+00	1194.00
IUUC-Csa-023700	Chlorocebus sabaeus	93.38	0.00e+00	1182.00
IUUC-Cgl-026480	Colletotrichum gloeosporioides	38.72	9.00e-69	255.00
IUUC-Dre-028387	Danio rerio	61.41	0.00e+00	813.00
IUUC-Dno-029052	Dasypus novemcinctus	60.30	0.00e+00	812.00
IUUC-Dor-030478	Dipodomys ordii	92.41	0.00e+00	1157.00
IUUC-Ete-032528	Echinops telfairi	60.21	4.00e-180	624.00
IUUC-Eca-033684	Equus caballus	92.32	0.00e+00	1023.00
IUUC-Eeu-034949	Erinaceus europaeus	71.85	8.00e-177	613.00
IUUC-Fca-035898	Felis catus	93.78	0.00e+00	1246.00
IUUC-Fal-037115	Ficedula albicollis	53.48	0.00e+00	667.00
IUUC-Gmo-039460	Gadus morhua	69.71	0.00e+00	870.00
IUUC-Gga-040502	Gallus gallus	56.65	0.00e+00	806.00
IUUC-Gac-042324	Gasterosteus aculeatus	66.31	0.00e+00	919.00
IUUC-Hsa-045897	Homo sapiens	95.80	0.00e+00	1239.00
IUUC-Itr-049080	Ictidomys tridecemlineatus	95.26	0.00e+00	1288.00
IUUC-Lch-049752	Latimeria chalumnae	65.68	0.00e+00	900.00
IUUC-Loc-052896	Lepisosteus oculatus	61.90	0.00e+00	810.00
IUUC-Laf-053534	Loxodonta africana	91.06	0.00e+00	1219.00
IUUC-Mcc-054804	Macaca mulatta	95.66	0.00e+00	1219.00
IUUC-Meu-056140	Macropus eugenii	91.20	0.00e+00	1242.00
IUUC-Mmr-060587	Microcebus murinus	94.85	0.00e+00	1248.00
IUUC-Mdo-062445	Monodelphis domestica	55.08	0.00e+00	807.00
IUUC-Mmu-064289	Mus musculus	93.90	0.00e+00	1259.00
IUUC-Mpu-066504	Mustela putorius furo	59.87	0.00e+00	825.00
IUUC-Mlu-067933	Myotis lucifugus	81.70	0.00e+00	999.00
IUUC-Nle-069719	Nomascus leucogenys	89.61	0.00e+00	983.00
IUUC-Opr-070607	Ochotona princeps	86.41	0.00e+00	1118.00
IUUC-Ont-071444	Oreochromis niloticus	67.64	0.00e+00	939.00
IUUC-Oan-072929	Ornithorhynchus anatinus	60.13	0.00e+00	813.00
IUUC-Ocu-073853	Oryctolagus cuniculus	59.87	0.00e+00	832.00
IUUC-Ola-086790	Oryzias latipes	62.75	0.00e+00	884.00
IUUC-Oga-088194	Otolemur garnettii	95.26	0.00e+00	1213.00
IUUC-Oar-089936	Ovis aries	84.44	0.00e+00	1107.00
IUUC-Ptr-091413	Pan troglodytes	95.93	0.00e+00	1222.00
IUUC-Pan-092891	Papio anubis	56.95	0.00e+00	815.00
IUUC-Psi-092994	Pelodiscus sinensis	60.00	0.00e+00	813.00
IUUC-Pma-094666	Petromyzon marinus	55.22	0.00e+00	783.00
IUUC-Pab-098074	Pongo abelii	94.98	0.00e+00	1200.00
IUUC-Pca-100975	Procavia capensis	62.37	1.00e-151	530.00
IUUC-Pva-103242	Pteropus vampyrus	95.66	0.00e+00	1192.00
IUUC-Pgr-103687	Puccinia graminis	47.45	1.00e-67	251.00
IUUC-Ptt-103944	Puccinia triticina	43.84	2.00e-65	244.00
IUUC-Rno-105368	Rattus norvegicus	94.04	0.00e+00	1236.00
IUUC-Sha-107115	Sarcophilus harrisii	60.26	0.00e+00	828.00
IUUC-Ssc-116439	Sus scrofa	70.91	2.00e-172	598.00
IUUC-Tgu-116652	Taeniopygia guttata	55.57	0.00e+00	751.00
IUUC-Tru-117575	Takifugu rubripes	65.49	0.00e+00	890.00
IUUC-Tsy-119138	Tarsius syrichta	59.24	8.00e-162	564.00
IUUC-Tni-120412	Tetraodon nigroviridis	54.57	0.00e+00	694.00
IUUC-Tme-127019	Tuber melanosporum	42.47	3.00e-68	253.00
IUUC-Tbe-127841	Tupaia belangeri	50.55	2.00e-171	595.00
IUUC-Ttr-129093	Tursiops truncatus	92.55	0.00e+00	1167.00
IUUC-Vpa-130477	Vicugna pacos	52.30	0.00e+00	714.00
IUUC-Xtr-132367	Xenopus tropicalis	68.69	0.00e+00	803.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence