iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089225

Ensembl Protein ID

ENSOARP00000004393.1

UniProt Accession

W5P1U4; W5P1U4_SHEEP

Genbank Protein ID

ENSOARP00000004393

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01017760

Gene Name

TRAF4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000004112.1	ENSOART00000004470.1	ENSOARP00000004393.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	8.40e-06	26.0	15	72
E3 activity/RING/RING	2.50e-06	28.1	18	56

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltl 61
            +lCp+ +++Mr+Pv ++ +G+ +  ++++++l++g  +cP ++ pl+  ++ P  +l
   Q: 15   RLLCPLCGKPMREPVQVStCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPEL 72
           689*************999*****************99*********99999998776 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPl 44
           C++C  ++++++ v  CgH f+ +Clq +     +s + f+CP 
   Q: 18   CPLCGKPMREPVQVSTCGHRFCDTCLQEF-----LSEGVFKCPE 56
           ********99888888**********999.....89*******6 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MPGFDYKFLE KPKRRLLCPL CGKPMREPVQ VSTCGHRFCD TCLQEFLSEG VFKCPEDQLP 60
LDYAKIYPDP ELEVQVLGLS IRCIHSEEAC RWNGPLRHLQ GHLNTCSFNV VPCPNRCPAK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCGGCT TCGACTACAA GTTCCTGGAG AAGCCCAAGC GGCGGCTGCT CTGCCCGCTG 60
TGCGGGAAGC CCATGCGCGA GCCCGTGCAG GTTTCTACCT GTGGCCACCG CTTCTGCGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR008974--TRAF-like
IPR027138--TRAF4
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0046330--P:positive regulation of JNK cascade
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0007585--P:respiratory gaseous exchange
GO:0030323--P:respiratory tube development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001287	Ailuropoda melanoleuca	92.96	0.00e+00	855.00
IUUC-Ame-011530	Astyanax mexicanus	74.89	0.00e+00	734.00
IUUC-Bta-013582	Bos taurus	95.74	0.00e+00	884.00
IUUC-Cja-019883	Callithrix jacchus	92.71	5.00e-51	192.00
IUUC-Cfa-020133	Canis familiaris	88.30	0.00e+00	807.00
IUUC-Cpo-022021	Cavia porcellus	94.47	0.00e+00	878.00
IUUC-Csa-023199	Chlorocebus sabaeus	94.89	0.00e+00	881.00
IUUC-Cgl-026455	Colletotrichum gloeosporioides	24.11	5.00e-16	79.00
IUUC-Dre-028193	Danio rerio	73.62	0.00e+00	728.00
IUUC-Dno-028917	Dasypus novemcinctus	94.68	0.00e+00	878.00
IUUC-Ete-032433	Echinops telfairi	93.62	0.00e+00	869.00
IUUC-Fca-036155	Felis catus	94.26	0.00e+00	875.00
IUUC-Gmo-038860	Gadus morhua	74.47	0.00e+00	729.00
IUUC-Gga-041052	Gallus gallus	77.87	0.00e+00	786.00
IUUC-Gac-041489	Gasterosteus aculeatus	74.47	0.00e+00	729.00
IUUC-Ggo-044996	Gorilla gorilla	94.47	0.00e+00	879.00
IUUC-Hsa-046252	Homo sapiens	94.68	0.00e+00	881.00
IUUC-Itr-048232	Ictidomys tridecemlineatus	94.89	0.00e+00	880.00
IUUC-Kpa-049340	Komagataella pastoris	25.40	1.00e-14	74.30
IUUC-Loc-052312	Lepisosteus oculatus	74.52	0.00e+00	729.00
IUUC-Lma-053014	Leptosphaeria maculans	23.18	5.00e-14	72.40
IUUC-Laf-054376	Loxodonta africana	94.89	0.00e+00	880.00
IUUC-Mcc-055684	Macaca mulatta	94.89	0.00e+00	881.00
IUUC-Mmr-061198	Microcebus murinus	94.89	0.00e+00	879.00
IUUC-Mdo-062585	Monodelphis domestica	85.11	0.00e+00	794.00
IUUC-Mmu-064303	Mus musculus	93.62	0.00e+00	874.00
IUUC-Mpu-066854	Mustela putorius furo	94.04	0.00e+00	874.00
IUUC-Nle-070098	Nomascus leucogenys	93.40	0.00e+00	867.00
IUUC-Ont-071518	Oreochromis niloticus	74.63	0.00e+00	730.00
IUUC-Ocu-073841	Oryctolagus cuniculus	94.68	0.00e+00	879.00
IUUC-Oba-075457	Oryza barthii	25.47	1.00e-09	57.40
IUUC-Ogu-078803	Oryza glumaepatula	25.47	8.00e-10	57.80
IUUC-Oin-079307	Oryza indica	25.47	7.00e-10	58.20
IUUC-Ome-081315	Oryza meridionalis	24.53	2.00e-10	60.50
IUUC-Oru-085055	Oryza rufipogon	25.47	1.00e-09	57.40
IUUC-Osa-085780	Oryza sativa	25.47	7.00e-10	58.20
IUUC-Ola-086674	Oryzias latipes	75.05	0.00e+00	731.00
IUUC-Oga-088510	Otolemur garnettii	94.26	0.00e+00	876.00
IUUC-Pan-092725	Papio anubis	94.89	0.00e+00	881.00
IUUC-Pfo-096341	Poecilia formosa	74.41	0.00e+00	730.00
IUUC-Pva-103131	Pteropus vampyrus	92.54	9.00e-134	469.00
IUUC-Rno-105996	Rattus norvegicus	93.83	0.00e+00	874.00
IUUC-Sly-111800	Solanum lycopersicum	29.17	3.00e-05	45.10
IUUC-Tru-117602	Takifugu rubripes	74.89	0.00e+00	737.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence