iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Spo-108186

Ensembl Protein ID

SPAC227.07c.1:pep

UniProt Accession

Q12702; Q9UTD2; 2ABA_SCHPO

Genbank Protein ID

BAA09945.1; CAB61456.1

Protein Name

Protein phosphatase PP2A regulatory subunit B; Protein phosphatase 2A 55 kDa regulatory subunit

Genbank Nucleotide ID

D63915; CU329670

Gene Name

pab1; SPAC227.07c

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPAC227.07c	SPAC227.07c.1	SPAC227.07c.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	Mentha
Post-translational Modifications (PTMs)
dbPAF	dbPTM	UniProt
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-13	48.0	91	120

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 5    svtclaf...sd.tllvsGsdDgtikvWDl 30
           +++ +++   ++  +++ +++D+tik+W l
   Q: 91   KINKIRWckrTNrAHFLLSTNDKTIKLWKL 120
           7999****986667788889********97 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Phosphatase 2A affects a variety of biological processes in the cell such as transcription, cell cycle progression and cellular morphogenesis, and provides an initial identification of critical substrates for this phosphatase. The regulatory subunit may direct the catalytic subunit to distinct, albeit overlapping, subsets of substrates.

Protein Sequence
(Fasta)

MDDIEDSLDQ WKFAQCFGDK GDVEDITEAD IISAVEFDHT GDYLATGDKG GRVVLFERNH 60
SKKGCEYKFF TEFQSHEPEF DYLKSLEIEE KINKIRWCKR TNRAHFLLST NDKTIKLWKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAATTTTA CTGAGCTTTT GACTCGCCGA AGAGTGGTGT AGATTCGTTA GGGTAGCAGC 60
ATTTGATACG AACCATCAAG TTAGGAAAAT CAGCAGCCCT CCAAAAAAGC CAGTGAAAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR000009--PP2A_PR55
IPR018067--PP2A_PR55_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS01024--PR55_1
PS01025--PR55_2
PS00678--WD_REPEATS_1

PRINTS

PR00600--PP2APR55

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0072686--C:mitotic spindle
GO:0000159--C:protein phosphatase type 2A complex
GO:0019888--F:protein phosphatase regulator activity
GO:0032502--P:developmental process
GO:0034260--P:negative regulation of GTPase activity
GO:0031030--P:negative regulation of septation initiation signaling
GO:0070262--P:peptidyl-serine dephosphorylation
GO:0035307--P:positive regulation of protein dephosphorylation

KEGG

spo:SPAC227.07c

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000361	Aegilops tauschii	50.00	4.00e-134	469.00
IUUC-Aml-001197	Ailuropoda melanoleuca	55.10	4.00e-130	456.00
IUUC-Atr-002520	Amborella trichopoda	51.49	9.00e-136	474.00
IUUC-Apl-004226	Anas platyrhynchos	55.10	2.00e-130	456.00
IUUC-Aca-004276	Anolis carolinensis	56.52	2.00e-135	473.00
IUUC-Aly-006304	Arabidopsis lyrata	50.90	3.00e-140	489.00
IUUC-Ath-007621	Arabidopsis thaliana	51.92	1.00e-139	487.00
IUUC-Ago-007825	Ashbya gossypii	60.71	2.00e-164	570.00
IUUC-Acl-008202	Aspergillus clavatus	67.23	1.00e-178	617.00
IUUC-Afl-008646	Aspergillus flavus	66.53	1.00e-180	623.00
IUUC-Afu-009027	Aspergillus fumigatus	67.16	3.00e-180	622.00
IUUC-Ani-009191	Aspergillus nidulans	67.78	0.00e+00	633.00
IUUC-Ang-009769	Aspergillus niger	68.41	0.00e+00	639.00
IUUC-Aor-010030	Aspergillus oryzae	68.11	3.00e-177	612.00
IUUC-Ate-010549	Aspergillus terreus	66.95	2.00e-178	616.00
IUUC-Ame-011776	Astyanax mexicanus	55.53	4.00e-129	452.00
IUUC-Bgr-012221	Blumeria graminis	65.34	0.00e+00	631.00
IUUC-Bta-012702	Bos taurus	55.10	3.00e-130	456.00
IUUC-Bci-013801	Botrytis cinerea	67.64	1.00e-179	620.00
IUUC-Bdi-014176	Brachypodium distachyon	51.79	1.00e-142	498.00
IUUC-Bol-015829	Brassica oleracea	53.49	2.00e-142	496.00
IUUC-Bra-017400	Brassica rapa	52.12	3.00e-142	496.00
IUUC-Cel-018618	Caenorhabditis elegans	54.12	3.00e-144	503.00
IUUC-Cja-019036	Callithrix jacchus	55.10	3.00e-130	456.00
IUUC-Cfa-021248	Canis familiaris	55.10	3.00e-130	456.00
IUUC-Cpo-022206	Cavia porcellus	56.74	2.00e-135	473.00
IUUC-Cre-022876	Chlamydomonas reinhardtii	52.88	2.00e-136	476.00
IUUC-Csa-023864	Chlorocebus sabaeus	55.10	3.00e-130	456.00
IUUC-Cho-024810	Choloepus hoffmanni	56.42	2.00e-131	460.00
IUUC-Cin-025380	Ciona intestinalis	54.07	2.00e-132	463.00
IUUC-Csv-026097	Ciona savignyi	53.28	5.00e-131	458.00
IUUC-Cgl-026750	Colletotrichum gloeosporioides	66.32	1.00e-180	624.00
IUUC-Cne-026887	Cryptococcus neoformans	69.81	0.00e+00	626.00
IUUC-Cme-027332	Cyanidioschyzon merolae	45.21	8.00e-112	395.00
IUUC-Dre-028727	Danio rerio	55.09	2.00e-126	443.00
IUUC-Dno-028876	Dasypus novemcinctus	55.87	3.00e-134	469.00
IUUC-Dor-030390	Dipodomys ordii	55.23	2.00e-123	433.00
IUUC-Dse-031305	Dothistroma septosporum	67.44	5.00e-179	618.00
IUUC-Dme-032131	Drosophila melanogaster	52.62	8.00e-130	454.00
IUUC-Ete-032410	Echinops telfairi	55.42	3.00e-89	320.00
IUUC-Eca-033882	Equus caballus	56.72	3.00e-133	466.00
IUUC-Eeu-034662	Erinaceus europaeus	29.00	2.00e-04	38.10
IUUC-Fca-035978	Felis catus	56.49	6.00e-133	465.00
IUUC-Fal-037650	Ficedula albicollis	56.06	9.00e-135	471.00
IUUC-Fox-037988	Fusarium oxysporum	67.37	2.00e-178	616.00
IUUC-Fso-038460	Fusarium solani	66.60	7.00e-180	621.00
IUUC-Gmo-039380	Gadus morhua	55.87	3.00e-134	469.00
IUUC-Ggr-039883	Gaeumannomyces graminis	67.65	0.00e+00	626.00
IUUC-Gga-040518	Gallus gallus	56.74	1.00e-135	474.00
IUUC-Gac-042418	Gasterosteus aculeatus	55.43	2.00e-133	466.00
IUUC-Gma-044053	Glycine max	52.28	9.00e-137	478.00
IUUC-Ggo-044599	Gorilla gorilla	55.10	3.00e-130	456.00
IUUC-Hsa-045992	Homo sapiens	56.09	6.00e-133	465.00
IUUC-Hvu-047813	Hordeum vulgare	52.16	3.00e-132	462.00
IUUC-Itr-048651	Ictidomys tridecemlineatus	55.10	3.00e-130	456.00
IUUC-Kpa-049100	Komagataella pastoris	62.96	2.00e-167	580.00
IUUC-Lch-050206	Latimeria chalumnae	56.02	5.00e-136	475.00
IUUC-Lpe-051334	Leersia perrieri	50.50	3.00e-134	469.00
IUUC-Loc-052535	Lepisosteus oculatus	56.09	6.00e-134	468.00
IUUC-Lma-053162	Leptosphaeria maculans	65.10	4.00e-176	608.00
IUUC-Laf-053403	Loxodonta africana	55.10	6.00e-130	455.00
IUUC-Mcc-054713	Macaca mulatta	56.09	9.00e-133	464.00
IUUC-Meu-056756	Macropus eugenii	52.38	4.00e-114	402.00
IUUC-Mor-057270	Magnaporthe oryzae	67.93	2.00e-179	619.00
IUUC-Mpo-057327	Magnaporthe poae	68.14	0.00e+00	629.00
IUUC-Mtr-058561	Medicago truncatula	51.39	1.00e-133	468.00
IUUC-Mla-059127	Melampsora laricipopulina	70.07	0.00e+00	648.00
IUUC-Mga-059946	Meleagris gallopavo	55.10	2.00e-130	456.00
IUUC-Mvi-060503	Microbotryum violaceum	65.98	6.00e-179	618.00
IUUC-Mmr-061468	Microcebus murinus	56.52	1.00e-135	474.00
IUUC-Mdo-062340	Monodelphis domestica	55.10	3.00e-130	456.00
IUUC-Mmu-063311	Mus musculus	56.96	2.00e-136	476.00
IUUC-Mac-065063	Musa acuminata	51.10	1.00e-135	474.00
IUUC-Mpu-066190	Mustela putorius furo	55.10	3.00e-130	456.00
IUUC-Mlu-066933	Myotis lucifugus	56.30	2.00e-134	469.00
IUUC-Nfi-068532	Neosartorya fischeri	66.88	4.00e-180	622.00
IUUC-Ncr-068905	Neurospora crassa	68.57	0.00e+00	638.00
IUUC-Nle-069840	Nomascus leucogenys	56.72	1.00e-132	464.00
IUUC-Opr-070857	Ochotona princeps	56.49	5.00e-131	459.00
IUUC-Ont-072224	Oreochromis niloticus	55.43	7.00e-133	464.00
IUUC-Oan-073540	Ornithorhynchus anatinus	63.21	1.00e-102	364.00
IUUC-Ocu-074222	Oryctolagus cuniculus	55.10	3.00e-130	456.00
IUUC-Oba-075715	Oryza barthii	51.50	7.00e-139	485.00
IUUC-Obr-076686	Oryza brachyantha	50.91	2.00e-135	473.00
IUUC-Ogl-077016	Oryza glaberrima	51.10	7.00e-138	481.00
IUUC-Ogu-078251	Oryza glumaepatula	51.20	2.00e-139	486.00
IUUC-Oin-079114	Oryza indica	51.50	4.00e-136	476.00
IUUC-Olo-080525	Oryza longistaminata	51.25	2.00e-132	464.00
IUUC-Ome-081711	Oryza meridionalis	51.21	3.00e-138	483.00
IUUC-Oni-082387	Oryza nivara	51.21	1.00e-136	478.00
IUUC-Opu-083739	Oryza punctata	51.20	2.00e-141	493.00
IUUC-Oru-084892	Oryza rufipogon	51.20	2.00e-139	486.00
IUUC-Osa-085869	Oryza sativa	51.10	4.00e-138	482.00
IUUC-Ola-086428	Oryzias latipes	55.91	1.00e-138	484.00
IUUC-Olu-087882	Ostreococcus lucimarinus	49.41	9.00e-132	461.00
IUUC-Oga-089168	Otolemur garnettii	55.10	2.00e-130	456.00
IUUC-Oar-089815	Ovis aries	55.10	4.00e-130	456.00
IUUC-Ptr-091110	Pan troglodytes	55.10	3.00e-130	456.00
IUUC-Pan-092846	Papio anubis	56.09	6.00e-133	465.00
IUUC-Psi-093292	Pelodiscus sinensis	56.52	7.00e-136	474.00
IUUC-Pma-094603	Petromyzon marinus	59.90	9.00e-62	227.00
IUUC-Pno-094992	Phaeosphaeria nodorum	66.26	6.00e-179	618.00
IUUC-Ppa-095378	Physcomitrella patens	50.87	4.00e-137	479.00
IUUC-Pfo-097174	Poecilia formosa	54.59	5.00e-129	452.00
IUUC-Pab-098146	Pongo abelii	55.10	3.00e-130	456.00
IUUC-Pop-099404	Populus trichocarpa	50.50	3.00e-134	469.00
IUUC-Pca-100882	Procavia capensis	54.17	6.00e-70	256.00
IUUC-Ppe-102006	Prunus persica	51.59	2.00e-136	477.00
IUUC-Pva-102279	Pteropus vampyrus	56.72	1.00e-132	464.00
IUUC-Pgr-103671	Puccinia graminis	62.22	2.00e-147	513.00
IUUC-Ptt-103844	Puccinia triticina	70.00	4.00e-175	605.00
IUUC-Pte-104403	Pyrenophora teres	65.50	2.00e-177	613.00
IUUC-Pyt-104776	Pyrenophora triticirepentis	65.31	2.00e-177	613.00
IUUC-Rno-105189	Rattus norvegicus	56.96	2.00e-136	476.00
IUUC-Sce-106284	Saccharomyces cerevisiae	65.86	6.00e-142	495.00
IUUC-Sha-106616	Sarcophilus harrisii	56.72	1.00e-133	467.00
IUUC-Sja-107757	Schizosaccharomyces japonicus	85.43	0.00e+00	786.00
IUUC-Smo-109077	Selaginella moellendorffii	52.66	3.00e-139	486.00
IUUC-Sit-110289	Setaria italica	51.50	9.00e-139	485.00
IUUC-Sly-111422	Solanum lycopersicum	51.40	4.00e-137	479.00
IUUC-Stu-111999	Solanum tuberosum	50.19	5.00e-132	462.00
IUUC-Sbi-114402	Sorghum bicolor	51.79	2.00e-136	477.00
IUUC-Sre-115166	Sporisorium reilianum	68.35	1.00e-172	597.00
IUUC-Ssc-115355	Sus scrofa	55.10	3.00e-130	456.00
IUUC-Tgu-116737	Taeniopygia guttata	54.88	9.00e-130	454.00
IUUC-Tru-118130	Takifugu rubripes	54.82	1.00e-128	450.00
IUUC-Tsy-119206	Tarsius syrichta	54.88	2.00e-124	437.00
IUUC-Tni-120009	Tetraodon nigroviridis	55.68	2.00e-128	450.00
IUUC-Tca-121708	Theobroma cacao	51.39	7.00e-134	468.00
IUUC-Tre-122188	Trichoderma reesei	65.18	2.00e-178	616.00
IUUC-Tvi-122271	Trichoderma virens	66.46	0.00e+00	625.00
IUUC-Tae-124837	Triticum aestivum	50.90	8.00e-140	488.00
IUUC-Tur-126203	Triticum urartu	51.14	1.00e-132	464.00
IUUC-Tme-127130	Tuber melanosporum	68.53	9.00e-176	607.00
IUUC-Tbe-127340	Tupaia belangeri	53.85	6.00e-119	418.00
IUUC-Ttr-128725	Tursiops truncatus	54.88	6.00e-128	448.00
IUUC-Uma-129346	Ustilago maydis	68.57	2.00e-173	599.00
IUUC-Vda-130007	Verticillium dahliae	67.15	2.00e-179	619.00
IUUC-Vpa-130425	Vicugna pacos	55.78	4.00e-130	456.00
IUUC-Vvi-130930	Vitis vinifera	51.77	4.00e-135	472.00
IUUC-Xtr-131852	Xenopus tropicalis	55.82	3.00e-134	469.00
IUUC-Xma-133921	Xiphophorus maculatus	55.48	4.00e-135	472.00
IUUC-Zma-135821	Zea mays	51.64	3.00e-130	456.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence