iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-091667

Ensembl Protein ID

ENSPTRP00000020124.4

UniProt Accession

H2QHJ1; H2QHJ1_PANTR

Genbank Protein ID

ENSPTRP00000020124

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03014278

Gene Name

ITSN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000011713.5	ENSPTRT00000021817.4	ENSPTRP00000020124.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.10e-61	202.5	1130	1182

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+++ydy a+n+deL++ kG  + v+  ++ d +W++g  e +g  GlfP+n+v+ 
   Q: 1130 QVIAMYDYAANNEDELSFSKGQLINVM--NKDDPDWWQG--EINGVTGLFPSNYVKM 1182
           6899**********************9..8899******..9*************85 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MMAQFPTAMN GGPNMWAITS EERTKHDRQF DNLKPSGGYI TGDQARNFFL QSGLPAPVLA 60
EIWALSDLNK DGKMDQQEFS IAMKLIKLKL QGQQLPVVLP PIMKQPPMFS PLISARFGMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGCCGCCAT GTTGTTGTGG GGCTGAGGCG GCGCCCGCGG AGCCCTGAGC CGCTGTGACG 60
GGCTACGCAA CAGGTTCGCG GGCGGCGGCC TGACGACCAA GCCAGCTGCA GTGGCGGCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR027029--Intersectin-2
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005813--C:centrosome
GO:0070062--C:extracellular exosome
GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:1903861--P:positive regulation of dendrite extension
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001455	Ailuropoda melanoleuca	93.88	0.00e+00	2162.00
IUUC-Apl-004205	Anas platyrhynchos	79.40	0.00e+00	2464.00
IUUC-Aca-004287	Anolis carolinensis	80.06	0.00e+00	1669.00
IUUC-Ame-011759	Astyanax mexicanus	65.07	0.00e+00	1259.00
IUUC-Bta-013248	Bos taurus	91.59	0.00e+00	2073.00
IUUC-Cel-018490	Caenorhabditis elegans	33.26	2.00e-53	204.00
IUUC-Cfa-020628	Canis familiaris	93.97	0.00e+00	2169.00
IUUC-Cpo-022427	Cavia porcellus	80.71	0.00e+00	2620.00
IUUC-Csa-023122	Chlorocebus sabaeus	95.02	0.00e+00	2225.00
IUUC-Cgl-026697	Colletotrichum gloeosporioides	28.46	3.00e-08	54.70
IUUC-Cne-026918	Cryptococcus neoformans	35.53	2.00e-38	155.00
IUUC-Dre-027849	Danio rerio	64.96	0.00e+00	1213.00
IUUC-Dno-029419	Dasypus novemcinctus	93.71	0.00e+00	2170.00
IUUC-Dor-030504	Dipodomys ordii	78.47	0.00e+00	1751.00
IUUC-Dme-032099	Drosophila melanogaster	33.19	1.00e-57	218.00
IUUC-Eca-034196	Equus caballus	92.01	0.00e+00	2065.00
IUUC-Eeu-034972	Erinaceus europaeus	68.87	0.00e+00	641.00
IUUC-Fca-035757	Felis catus	93.55	0.00e+00	2180.00
IUUC-Fal-037531	Ficedula albicollis	87.72	0.00e+00	1758.00
IUUC-Gga-041012	Gallus gallus	79.67	0.00e+00	1912.00
IUUC-Ggo-045405	Gorilla gorilla	94.80	0.00e+00	2801.00
IUUC-Hsa-046833	Homo sapiens	99.02	0.00e+00	2216.00
IUUC-Lch-050094	Latimeria chalumnae	74.31	0.00e+00	1690.00
IUUC-Loc-052646	Lepisosteus oculatus	71.52	0.00e+00	1459.00
IUUC-Laf-053798	Loxodonta africana	87.50	0.00e+00	1435.00
IUUC-Mcc-054709	Macaca mulatta	98.37	0.00e+00	2235.00
IUUC-Meu-056396	Macropus eugenii	80.04	0.00e+00	1541.00
IUUC-Mga-059997	Meleagris gallopavo	83.76	0.00e+00	2045.00
IUUC-Mvi-060268	Microbotryum violaceum	30.33	4.00e-46	181.00
IUUC-Mmr-060891	Microcebus murinus	92.82	0.00e+00	2217.00
IUUC-Mmu-064226	Mus musculus	87.42	0.00e+00	2145.00
IUUC-Mpu-066431	Mustela putorius furo	90.78	0.00e+00	2144.00
IUUC-Mlu-068190	Myotis lucifugus	93.96	0.00e+00	2167.00
IUUC-Nle-070116	Nomascus leucogenys	95.98	0.00e+00	1796.00
IUUC-Opr-070815	Ochotona princeps	79.69	0.00e+00	1782.00
IUUC-Ont-072464	Oreochromis niloticus	65.40	0.00e+00	1247.00
IUUC-Ocu-073856	Oryctolagus cuniculus	79.43	0.00e+00	1907.00
IUUC-Ola-086482	Oryzias latipes	61.38	0.00e+00	1233.00
IUUC-Oga-088449	Otolemur garnettii	92.98	0.00e+00	2122.00
IUUC-Oar-090275	Ovis aries	92.16	0.00e+00	2117.00
IUUC-Pan-091723	Papio anubis	92.19	0.00e+00	1905.00
IUUC-Psi-093136	Pelodiscus sinensis	82.33	0.00e+00	1957.00
IUUC-Pab-098755	Pongo abelii	96.08	0.00e+00	2129.00
IUUC-Pca-101134	Procavia capensis	86.24	0.00e+00	1504.00
IUUC-Pva-102433	Pteropus vampyrus	83.51	0.00e+00	1902.00
IUUC-Pgr-103473	Puccinia graminis	29.97	4.00e-38	154.00
IUUC-Ptt-103973	Puccinia triticina	25.26	4.00e-27	117.00
IUUC-Rno-105691	Rattus norvegicus	91.92	0.00e+00	2212.00
IUUC-Sar-112978	Sorex araneus	90.34	0.00e+00	1427.00
IUUC-Sre-115028	Sporisorium reilianum	36.71	2.00e-33	139.00
IUUC-Ssc-115562	Sus scrofa	86.45	0.00e+00	1937.00
IUUC-Tgu-116758	Taeniopygia guttata	82.43	0.00e+00	2021.00
IUUC-Tni-119958	Tetraodon nigroviridis	56.00	0.00e+00	1691.00
IUUC-Tbe-127477	Tupaia belangeri	92.50	0.00e+00	760.00
IUUC-Ttr-129196	Tursiops truncatus	91.60	0.00e+00	2075.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence