iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000000953.1	ENSAMET00000001051.1	ENSAMEP00000001011.1
ENSAMEG00000000953.1	ENSAMET00000001055.1	ENSAMEP00000001015.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.80e-28	95.5	153	192
UBD/Beta-Prp	9.20e-56	189.3	495	757

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgvll 36
           gH+ +v c+af ++ +++vs +  +D ++ vWD++++v++
   Q: 153  GHKYGVACVAFsPSmKHIVSMGyqHDMVLNVWDWKKDVVV 192
           89**********777*****9989**********999876 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdls.tgkcvhtlkghedsv 97
           ++++++spd+++la+g r+g +++++++ ++ l +++ h+aev ++++s+ +    +l+++s+Dr+i+v +++ ++   +tl  h++s+
   Q: 495  VRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETgltLLASASRDRLIHVLNVEkNYNLEQTLDDHSSSI 583
           67899*******************************************99887899**************9997888899********* PP
   S: 98   lslsfspsg.dklvsGshdrtirv.wdletgqcleetlsghdg...vvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltgg 178
           ++++f  ++   ++s ++d+ i      +t   l+ + + h +   +   + ++ ++++++ ++ Dr vr+++    k+ k+ +  +g 
   Q: 584  TAIKFAGNRdIQMISCGADKSIYFrSAQRTLDGLRFVRTHHVAektTLYDMDIDITQKYVAVACQDRNVRVYNTvsgKQRKCYKGSQG- 671
           *******885789*******9977544444444442333333300033346777788****************977788888888888. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW.......dlrsgdll 257
           +++s  ++ +d++g++l++   d+++ + d+ +gecv ++ gh++ v+ ++f+ +  +l+++s D  ++iW       ++ ++ ll
   Q: 672  DEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECVAKMFGHSEIVTGMKFTYDCRHLITVSGDSCVFIWhlgpeitNCMKQHLL 757
           999999999**************************************************************776666655555544 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MAALGPGGYA RNDAVEKLPS VTVGVPARRG QCSPPPAPPL CLRRRTRLSA ASEDTVQNRV 60
SLEKVLGITA QNSSGLTCDP STGHVAYLAG CVVVILNPKE NKQQHIFNTA RKSLSALAFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCCT TGGGTCCCGG AGGCTACGCG CGGAACGATG CTGTCGAGAA GCTGCCATCC 60
GTCACGGTGG GAGTTCCGGC GCGGAGGGGC CAGTGCTCTC CTCCCCCCGC TCCGCCGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0007099--P:centriole replication
GO:0021987--P:cerebral cortex development
GO:0007052--P:mitotic spindle organization
GO:0022008--P:neurogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-003165	Amborella trichopoda	34.55	4.00e-126	446.00
IUUC-Aca-004935	Anolis carolinensis	71.15	0.00e+00	1009.00
IUUC-Ath-007624	Arabidopsis thaliana	30.83	4.00e-94	339.00
IUUC-Afu-008757	Aspergillus fumigatus	21.61	3.00e-28	120.00
IUUC-Bta-013336	Bos taurus	82.13	0.00e+00	2310.00
IUUC-Cel-018592	Caenorhabditis elegans	28.57	1.00e-71	265.00
IUUC-Cja-019094	Callithrix jacchus	80.20	0.00e+00	2265.00
IUUC-Cfa-020529	Canis familiaris	90.38	0.00e+00	2628.00
IUUC-Cpo-021970	Cavia porcellus	86.48	0.00e+00	1640.00
IUUC-Csa-024161	Chlorocebus sabaeus	81.16	0.00e+00	2255.00
IUUC-Cho-024310	Choloepus hoffmanni	85.43	0.00e+00	1162.00
IUUC-Cgl-026454	Colletotrichum gloeosporioides	22.75	2.00e-23	104.00
IUUC-Dre-028678	Danio rerio	56.91	0.00e+00	1001.00
IUUC-Dno-029933	Dasypus novemcinctus	78.35	0.00e+00	2204.00
IUUC-Dor-031147	Dipodomys ordii	77.34	0.00e+00	2106.00
IUUC-Dse-031501	Dothistroma septosporum	27.99	2.00e-23	105.00
IUUC-Eca-033675	Equus caballus	84.43	0.00e+00	2396.00
IUUC-Eeu-034798	Erinaceus europaeus	89.17	0.00e+00	900.00
IUUC-Fca-035826	Felis catus	88.04	0.00e+00	2585.00
IUUC-Gma-043644	Glycine max	31.93	9.00e-103	368.00
IUUC-Ggo-045152	Gorilla gorilla	82.92	0.00e+00	2262.00
IUUC-Hsa-045891	Homo sapiens	82.92	0.00e+00	2295.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	92.76	0.00e+00	1554.00
IUUC-Lch-049669	Latimeria chalumnae	58.15	0.00e+00	1006.00
IUUC-Loc-052488	Lepisosteus oculatus	60.45	0.00e+00	1030.00
IUUC-Laf-053992	Loxodonta africana	80.20	0.00e+00	2282.00
IUUC-Mcc-054994	Macaca mulatta	82.53	0.00e+00	2248.00
IUUC-Meu-056815	Macropus eugenii	80.07	0.00e+00	1405.00
IUUC-Mtr-058383	Medicago truncatula	30.30	6.00e-50	191.00
IUUC-Mmr-060693	Microcebus murinus	80.60	0.00e+00	2240.00
IUUC-Mdo-063007	Monodelphis domestica	61.69	0.00e+00	1771.00
IUUC-Mmu-064067	Mus musculus	75.02	0.00e+00	2138.00
IUUC-Mpu-066532	Mustela putorius furo	92.46	0.00e+00	2731.00
IUUC-Mlu-066982	Myotis lucifugus	81.64	0.00e+00	2269.00
IUUC-Nle-070042	Nomascus leucogenys	84.99	0.00e+00	1919.00
IUUC-Opr-070397	Ochotona princeps	78.80	0.00e+00	2244.00
IUUC-Oan-073119	Ornithorhynchus anatinus	66.81	0.00e+00	873.00
IUUC-Ocu-074274	Oryctolagus cuniculus	81.03	0.00e+00	2219.00
IUUC-Oga-088577	Otolemur garnettii	82.31	0.00e+00	2347.00
IUUC-Oar-090117	Ovis aries	80.92	0.00e+00	2276.00
IUUC-Ptr-090553	Pan troglodytes	82.86	0.00e+00	2312.00
IUUC-Pan-092559	Papio anubis	73.70	0.00e+00	1082.00
IUUC-Psi-093710	Pelodiscus sinensis	65.43	0.00e+00	1397.00
IUUC-Pno-094837	Phaeosphaeria nodorum	23.68	2.00e-32	134.00
IUUC-Pab-098510	Pongo abelii	81.62	0.00e+00	2188.00
IUUC-Pop-099155	Populus trichocarpa	31.60	1.00e-97	352.00
IUUC-Pca-100323	Procavia capensis	71.18	0.00e+00	1310.00
IUUC-Pva-102895	Pteropus vampyrus	85.63	0.00e+00	2450.00
IUUC-Rno-105598	Rattus norvegicus	75.97	0.00e+00	2153.00
IUUC-Sha-107013	Sarcophilus harrisii	66.43	0.00e+00	1800.00
IUUC-Smo-109134	Selaginella moellendorffii	37.25	2.00e-135	477.00
IUUC-Sar-113261	Sorex araneus	76.76	0.00e+00	2168.00
IUUC-Ssc-115317	Sus scrofa	83.84	0.00e+00	2312.00
IUUC-Tsy-118799	Tarsius syrichta	90.81	0.00e+00	855.00
IUUC-Tni-120316	Tetraodon nigroviridis	56.35	0.00e+00	786.00
IUUC-Tca-121475	Theobroma cacao	30.42	8.00e-98	352.00
IUUC-Tvi-122281	Trichoderma virens	23.52	6.00e-29	123.00
IUUC-Tme-127128	Tuber melanosporum	23.89	1.00e-30	128.00
IUUC-Tbe-127555	Tupaia belangeri	93.78	0.00e+00	1025.00
IUUC-Ttr-128722	Tursiops truncatus	83.59	0.00e+00	2367.00
IUUC-Vda-129957	Verticillium dahliae	22.97	4.00e-30	127.00
IUUC-Vpa-130392	Vicugna pacos	73.50	3.00e-114	405.00
IUUC-Vvi-131035	Vitis vinifera	34.17	1.00e-108	387.00
IUUC-Xtr-131789	Xenopus tropicalis	59.51	0.00e+00	988.00
IUUC-Yli-134437	Yarrowia lipolytica	27.06	3.00e-16	80.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence