iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-024161

Ensembl Protein ID

ENSCSAP00000000615.1

UniProt Accession

A0A0D9QW76; A0A0D9QW76_CHLSB

Genbank Protein ID

ENSCSAP00000000615

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01134473

Gene Name

WDR62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000004269.1	ENSCSAT00000002293.1	ENSCSAP00000000615.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.60e-27	92.4	149	186
UBD/Beta-Prp	1.00e-54	185.7	493	749

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgv 34
           gH+ +v c+af ++ +++vs +  +D ++ vWD++++ 
   Q: 149  GHKYGVACVAFsPNmKHIVSMGyqHDMVLNVWDWKKDI 186
           89**********888*****9989*********98765 PP

UBD/Beta-Prp

   S: 15   cvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdls.tgkcvhtlkghedsvls 99
           ++++spd+++la+g r+g +++++++ ++ l +++ h+aev ++++s+ +    +l+++s+Dr+i+v +++ ++   +tl  h++s+++
   Q: 493  VMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETgltLLASASRDRLIHVLNVEkNYNLEQTLDDHSSSITA 581
           5899******************************************99888899****************97888999*********** PP
   S: 100  lsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltgght 180
           ++f  ++   ++s ++d+ i     + g+   +        ++ +   + ++ ++++++ ++ Dr vr+++    k++k+ +  +g ++
   Q: 582  IKFAGNRdIQMISCGADKSIYFRSAQRGSDGLHfvrtHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTvngKQKKCYKGSQG-DE 669
           *****88578**********98555555544444332111222233446677778****************988888888888898.99 PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW.......dlrs 253
           +s  ++ +d++g++l++   d+++ + d+ +gec+ ++ gh++ ++s++f+ + ++l+++s D  ++iW       ++ +
   Q: 670  GSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITSMKFTYDCHHLITVSGDSCVFIWhlgpeitNCMK 749
           9999999**************************************************************66554444443 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MAAVGSGGCA RNDAGEKLPS VMAGVPARRG QSSPPLCLRR RTRLSTASEE TVQNRVSLEK 60
VLGITAQNSS GLTCDPGTGH VAYLAGCVVV ILDPKENKQQ HIFNTARKSL SALAFSPDGK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCCG TAGGGTCTGG AGGCTGTGCG CGGAACGATG CAGGGGAGAA GCTGCCCTCT 60
GTCATGGCGG GAGTTCCGGC GCGGAGGGGT CAGTCCTCCC CACCGCTCTG CCTCCGGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0007099--P:centriole replication
GO:0021987--P:cerebral cortex development
GO:0007052--P:mitotic spindle organization
GO:0022008--P:neurogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001371	Ailuropoda melanoleuca	80.18	0.00e+00	2322.00
IUUC-Aca-004935	Anolis carolinensis	71.60	0.00e+00	1012.00
IUUC-Afu-008757	Aspergillus fumigatus	21.34	4.00e-28	120.00
IUUC-Bta-013336	Bos taurus	77.96	0.00e+00	2211.00
IUUC-Cel-018592	Caenorhabditis elegans	28.78	4.00e-74	273.00
IUUC-Cja-019094	Callithrix jacchus	88.79	0.00e+00	2565.00
IUUC-Cfa-020529	Canis familiaris	80.21	0.00e+00	2338.00
IUUC-Cpo-021970	Cavia porcellus	85.66	0.00e+00	1632.00
IUUC-Cre-022999	Chlamydomonas reinhardtii	28.38	1.00e-13	71.60
IUUC-Cho-024310	Choloepus hoffmanni	84.95	0.00e+00	1169.00
IUUC-Cgl-026454	Colletotrichum gloeosporioides	22.89	3.00e-24	107.00
IUUC-Dno-029933	Dasypus novemcinctus	73.94	0.00e+00	2078.00
IUUC-Dor-031147	Dipodomys ordii	76.24	0.00e+00	2078.00
IUUC-Eca-033675	Equus caballus	79.34	0.00e+00	2228.00
IUUC-Eeu-034798	Erinaceus europaeus	86.27	0.00e+00	891.00
IUUC-Fca-035826	Felis catus	79.83	0.00e+00	2341.00
IUUC-Gma-043644	Glycine max	31.60	4.00e-101	363.00
IUUC-Ggo-045152	Gorilla gorilla	94.16	0.00e+00	2658.00
IUUC-Hsa-045891	Homo sapiens	94.62	0.00e+00	2660.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	89.44	0.00e+00	1513.00
IUUC-Lch-049669	Latimeria chalumnae	57.52	0.00e+00	999.00
IUUC-Loc-052488	Lepisosteus oculatus	58.87	0.00e+00	1008.00
IUUC-Laf-053992	Loxodonta africana	77.02	0.00e+00	2227.00
IUUC-Mcc-054994	Macaca mulatta	96.91	0.00e+00	2725.00
IUUC-Meu-056815	Macropus eugenii	79.79	0.00e+00	1385.00
IUUC-Mtr-058383	Medicago truncatula	30.43	6.00e-50	191.00
IUUC-Mmr-060693	Microcebus murinus	77.57	0.00e+00	2173.00
IUUC-Mdo-063007	Monodelphis domestica	61.87	0.00e+00	1697.00
IUUC-Mmu-064067	Mus musculus	73.92	0.00e+00	2108.00
IUUC-Mpu-066532	Mustela putorius furo	80.34	0.00e+00	2358.00
IUUC-Mlu-066982	Myotis lucifugus	76.07	0.00e+00	2095.00
IUUC-Nle-070042	Nomascus leucogenys	82.67	0.00e+00	2249.00
IUUC-Opr-070397	Ochotona princeps	78.41	0.00e+00	2276.00
IUUC-Ocu-074274	Oryctolagus cuniculus	79.10	0.00e+00	2180.00
IUUC-Oga-088577	Otolemur garnettii	80.43	0.00e+00	2320.00
IUUC-Oar-090117	Ovis aries	74.97	0.00e+00	2115.00
IUUC-Ptr-090553	Pan troglodytes	94.81	0.00e+00	2690.00
IUUC-Pan-092559	Papio anubis	96.85	0.00e+00	1515.00
IUUC-Psi-093710	Pelodiscus sinensis	62.66	0.00e+00	1345.00
IUUC-Pab-098510	Pongo abelii	92.89	0.00e+00	2586.00
IUUC-Pca-100323	Procavia capensis	70.96	0.00e+00	1344.00
IUUC-Pva-102895	Pteropus vampyrus	79.18	0.00e+00	2253.00
IUUC-Rno-105598	Rattus norvegicus	74.35	0.00e+00	2150.00
IUUC-Sha-107013	Sarcophilus harrisii	66.31	0.00e+00	1773.00
IUUC-Sar-113261	Sorex araneus	73.81	0.00e+00	2049.00
IUUC-Ssc-115317	Sus scrofa	78.42	0.00e+00	2162.00
IUUC-Tsy-118799	Tarsius syrichta	92.34	0.00e+00	869.00
IUUC-Tvi-122281	Trichoderma virens	23.85	3.00e-30	127.00
IUUC-Tme-127128	Tuber melanosporum	23.53	1.00e-31	132.00
IUUC-Tbe-127555	Tupaia belangeri	91.41	0.00e+00	1008.00
IUUC-Ttr-128722	Tursiops truncatus	78.76	0.00e+00	2230.00
IUUC-Vda-129957	Verticillium dahliae	23.20	4.00e-30	127.00
IUUC-Vpa-130392	Vicugna pacos	65.30	7.00e-98	351.00
IUUC-Xtr-131789	Xenopus tropicalis	59.39	0.00e+00	976.00
IUUC-Yli-134437	Yarrowia lipolytica	25.88	3.00e-16	80.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence