iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-045152

Ensembl Protein ID

ENSGGOP00000001132.2

UniProt Accession

G3QFQ3; G3QFQ3_GORGO

Protein Name

Uncharacterized protein

Gene Name

WDR62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000001147.2	ENSGGOT00000001156.2	ENSGGOP00000001132.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.80e-27	94.0	153	190
UBD/Beta-Prp	6.50e-55	186.8	495	753

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgv 34
           gH+ +v c+af ++ +++vs +  +D ++ vWD++++ 
   Q: 153  GHKYGVACVAFsPNmKHIVSMGyqHDMVLNVWDWKKDI 190
           89**********888*****9989*********98765 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdls.tgkcvhtlkghedsv 97
           ++++++spd+++la+g r+g +++++++ ++ l +++ h+aev ++++s+ +    +l+++s+Dr+i+v +++ ++   +tl  h++s+
   Q: 495  VRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETgltLLASASRDRLIHVLNVEkNYNLEQTLDDHSSSI 583
           67899*******************************************99887899**************9997888999********* PP
   S: 98   lslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltgg 178
           ++++f  ++   ++s ++d+ i     ++g+   +        ++ +   + ++ ++++++ ++ Dr vr+++    k++k+ +  +g 
   Q: 584  TAIKFAGNRdIQMISCGADKSIYFRSAQQGSDGLHfvrtHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTvngKQKKCYKGSQG- 671
           *******885789********998666666555544332112222233446677778****************988888888888898. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW.......dlrs 253
           +++s  ++ +d++g++l++   d+++ + d+ +gec+ ++ gh++ ++s++f+ + ++l+++s D  ++iW       ++ +
   Q: 672  DEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITSMKFTYDCHHLITVSGDSCVFIWhlgpeitNCMK 753
           999999999**************************************************************66554444433 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MAAVGSGGYA RNDAGEKLPS VMAGVPARRG QSSPPPAPPL CLRRRTRLST ASEETVQNRV 60
SLEKVLGITA QNSSGLTCDP GAGHVAYLAG CVVVILDPKE NKQQHIFNTA RKSLSALAFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCCCGCGG CTGTTCGCTG TTCCAGTGGG TCGTGGCGGT GGCGGCAGCG GCGGTTAGGG 60
GATGTAACGG TCGCCCGGCT CCGGCGTGAC GATGGCGGCC GTAGGGTCCG GAGGCTATGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0007099--P:centriole replication
GO:0021987--P:cerebral cortex development
GO:0007052--P:mitotic spindle organization
GO:0022008--P:neurogenesis

KEGG

ggo:101126641

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001371	Ailuropoda melanoleuca	82.46	0.00e+00	2375.00
IUUC-Atr-003165	Amborella trichopoda	33.79	1.00e-122	434.00
IUUC-Aca-004935	Anolis carolinensis	71.45	0.00e+00	1011.00
IUUC-Ath-007624	Arabidopsis thaliana	30.10	4.00e-91	329.00
IUUC-Acl-008257	Aspergillus clavatus	21.22	2.00e-22	101.00
IUUC-Bta-013336	Bos taurus	79.86	0.00e+00	2237.00
IUUC-Cel-018592	Caenorhabditis elegans	28.78	2.00e-74	275.00
IUUC-Cja-019094	Callithrix jacchus	90.89	0.00e+00	2622.00
IUUC-Cfa-020529	Canis familiaris	82.41	0.00e+00	2374.00
IUUC-Cpo-021970	Cavia porcellus	87.27	0.00e+00	1665.00
IUUC-Cre-022999	Chlamydomonas reinhardtii	28.38	1.00e-13	71.60
IUUC-Csa-024161	Chlorocebus sabaeus	94.81	0.00e+00	2714.00
IUUC-Cho-024310	Choloepus hoffmanni	84.95	0.00e+00	1170.00
IUUC-Cin-025412	Ciona intestinalis	52.41	4.00e-58	217.00
IUUC-Cgl-026454	Colletotrichum gloeosporioides	22.85	3.00e-24	107.00
IUUC-Dre-028678	Danio rerio	56.78	0.00e+00	1004.00
IUUC-Dno-029933	Dasypus novemcinctus	75.55	0.00e+00	2110.00
IUUC-Dor-031147	Dipodomys ordii	77.66	0.00e+00	2120.00
IUUC-Eca-033675	Equus caballus	80.89	0.00e+00	2278.00
IUUC-Fca-035826	Felis catus	81.33	0.00e+00	2395.00
IUUC-Gma-043644	Glycine max	31.33	2.00e-100	360.00
IUUC-Hsa-045891	Homo sapiens	98.62	0.00e+00	2800.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	91.81	0.00e+00	1550.00
IUUC-Lch-049669	Latimeria chalumnae	58.46	0.00e+00	1019.00
IUUC-Loc-052488	Lepisosteus oculatus	55.91	0.00e+00	1024.00
IUUC-Laf-053992	Loxodonta africana	79.06	0.00e+00	2281.00
IUUC-Mcc-054994	Macaca mulatta	96.59	0.00e+00	2712.00
IUUC-Meu-056815	Macropus eugenii	78.80	0.00e+00	1416.00
IUUC-Mtr-058383	Medicago truncatula	30.21	9.00e-50	191.00
IUUC-Mmr-060693	Microcebus murinus	80.22	0.00e+00	2229.00
IUUC-Mdo-063007	Monodelphis domestica	61.88	0.00e+00	1760.00
IUUC-Mmu-064067	Mus musculus	75.38	0.00e+00	2150.00
IUUC-Mpu-066532	Mustela putorius furo	82.80	0.00e+00	2418.00
IUUC-Mlu-066982	Myotis lucifugus	77.88	0.00e+00	2132.00
IUUC-Nle-070042	Nomascus leucogenys	97.66	0.00e+00	2163.00
IUUC-Opr-070397	Ochotona princeps	79.58	0.00e+00	2292.00
IUUC-Ocu-074274	Oryctolagus cuniculus	80.59	0.00e+00	2214.00
IUUC-Oga-088577	Otolemur garnettii	82.64	0.00e+00	2366.00
IUUC-Oar-090117	Ovis aries	77.11	0.00e+00	2155.00
IUUC-Ptr-090553	Pan troglodytes	98.62	0.00e+00	2824.00
IUUC-Pan-092559	Papio anubis	94.83	0.00e+00	1502.00
IUUC-Psi-093710	Pelodiscus sinensis	63.34	0.00e+00	1384.00
IUUC-Pab-098510	Pongo abelii	95.73	0.00e+00	2648.00
IUUC-Pca-100323	Procavia capensis	72.08	0.00e+00	1342.00
IUUC-Pva-102895	Pteropus vampyrus	81.59	0.00e+00	2315.00
IUUC-Rno-105598	Rattus norvegicus	75.88	0.00e+00	2191.00
IUUC-Sha-107013	Sarcophilus harrisii	67.11	0.00e+00	1804.00
IUUC-Smo-109134	Selaginella moellendorffii	36.95	2.00e-133	470.00
IUUC-Sar-113261	Sorex araneus	74.84	0.00e+00	2071.00
IUUC-Ssc-115317	Sus scrofa	80.82	0.00e+00	2227.00
IUUC-Tsy-118799	Tarsius syrichta	92.12	0.00e+00	867.00
IUUC-Tni-120316	Tetraodon nigroviridis	55.62	0.00e+00	777.00
IUUC-Tca-121475	Theobroma cacao	30.54	2.00e-95	343.00
IUUC-Tme-127128	Tuber melanosporum	23.42	2.00e-32	135.00
IUUC-Tbe-127555	Tupaia belangeri	93.42	0.00e+00	1015.00
IUUC-Ttr-128722	Tursiops truncatus	80.03	0.00e+00	2266.00
IUUC-Vda-129957	Verticillium dahliae	22.89	1.00e-29	125.00
IUUC-Vpa-130392	Vicugna pacos	68.77	5.00e-108	385.00
IUUC-Vvi-131035	Vitis vinifera	33.24	6.00e-104	372.00
IUUC-Xtr-131789	Xenopus tropicalis	60.00	0.00e+00	993.00
IUUC-Yli-134437	Yarrowia lipolytica	25.68	2.00e-16	81.30

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence