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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Rno-105598
Ensembl Protein ID ENSRNOP00000061740.2
UniProt Accession F1M5K2; F1M5K2_RAT
Genbank Protein ID ENSRNOP00000061740
Protein Name WD repeat domain 62
Genbank Nucleotide ID AABR07002905
Gene Name Wdr62; LOC100911863; NEWGENE_1306714
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000020807.7 ENSRNOT00000082555.1 ENSRNOP00000071039.1
ENSRNOG00000020807.7 ENSRNOT00000065011.2 ENSRNOP00000061740.2
Annotation
mRNA Expression
ArrayExpress
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.10e-28 98.4 425 450
UBD/Beta-Prp 5.00e-53 180.6 492 745
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 12   sdtllvsGsdDgtikvWDlrtgvllk 37
           ++++++++s D+ti+ W++++g +++
   Q: 425  PSGTFLTCSSDNTIRFWNMDSGSDTQ 450
           55789***************998875 PP
   

   UBD/Beta-Prp
   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdls.tgkcvhtlkgh 93
           +k+ ++++++spd+++la+g r+g +++++++ ++ l +++ h+aev ++++s+ +    +l+++s+Dr+i+v +++ ++   +tl  h
   Q: 492  MKAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELIKVEAHDAEVLCLEYSKPETgvtLLASASRDRLIHVLNVEkNYNLEQTLDDH 580
           66778889999999999999999999999999999999999999999999999887778999999999999999999778888999999 PP
   S: 94   edsvlslsfspsg.dklvsGshdrtirv.wdletgqcleetlsghdg...vvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrt 174
           ++s+++++f  ++   ++s ++d+ i      +t   l+ + + h +   +   + ++ ++++++ ++ Dr vr+++    k++k+ + 
   Q: 581  SSSITAIKFAGTRdVQMISCGADKSIYFrSAQQTSDGLHFVRTHHVAektTLYDMDIDITQKYVAVACQDRNVRVYNTvsgKQKKCYKG 669
           99999999999774779999999999875444444444423333332000233456777789999999999999999977777788888 PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
            +g +++s  ++ +d++g++l++   d+++ + d+ +gecv ++ gh++ v+ ++f+ +  +l+++s D  ++iW l
   Q: 670  SQG-DEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECVAKMFGHSEIVTGMKFTYDCRHLITVSGDSCVFIWHL 745
           888.9999999999999999999999999999999999999999999999999999999999999999999999943 PP
   
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MMAALAAGGY ARSDTIEKLS SVMAGVPARR NQSSPPPAPP LCLRRRTRLA AAPEDTVQNR 60
VTLEKVLGIT AQNSSGLTCD PGTGHVAYLA GCVVVVLNPK ENKQQHIFNT TRKSLSALAF 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105598|E3,WD_repeat;UBD,Beta-Prp|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGATGGCTG CCTTAGCGGC CGGAGGTTAC GCGCGGAGTG ACACGATAGA AAAGCTGTCC 60
TCTGTCATGG CGGGAGTTCC GGCGCGGAGA AACCAGTCCT CCCCGCCTCC TGCCCCACCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105598|E3,WD_repeat;UBD,Beta-Prp|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0002052--P:positive regulation of neuroblast proliferation
GO:2001224--P:positive regulation of neuron migration
GO:0046605--P:regulation of centrosome cycle
GO:0045664--P:regulation of neuron differentiation
KEGG rno:308492
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001371 Ailuropoda melanoleuca 76.00 0.00e+00 2191.00
IUUC-Atr-003165 Amborella trichopoda 34.87 3.00e-126 446.00
IUUC-Aca-004935 Anolis carolinensis 71.00 0.00e+00 1003.00
IUUC-Afl-008426 Aspergillus flavus 22.81 1.00e-28 122.00
IUUC-Afu-008757 Aspergillus fumigatus 22.04 2.00e-29 124.00
IUUC-Aor-009966 Aspergillus oryzae 22.81 1.00e-28 122.00
IUUC-Bta-013336 Bos taurus 73.92 0.00e+00 2091.00
IUUC-Cja-019094 Callithrix jacchus 75.02 0.00e+00 2138.00
IUUC-Cfa-020529 Canis familiaris 75.96 0.00e+00 2212.00
IUUC-Cpo-021970 Cavia porcellus 83.00 0.00e+00 1612.00
IUUC-Csa-024161 Chlorocebus sabaeus 74.98 0.00e+00 2127.00
IUUC-Cho-024310 Choloepus hoffmanni 78.76 0.00e+00 1103.00
IUUC-Cin-025412 Ciona intestinalis 50.73 5.00e-59 220.00
IUUC-Cgl-026454 Colletotrichum gloeosporioides 23.87 1.00e-25 112.00
IUUC-Dno-029933 Dasypus novemcinctus 71.93 0.00e+00 2008.00
IUUC-Dor-031147 Dipodomys ordii 73.67 0.00e+00 2048.00
IUUC-Dse-031501 Dothistroma septosporum 23.78 3.00e-34 140.00
IUUC-Eca-033675 Equus caballus 75.92 0.00e+00 2143.00
IUUC-Fca-035826 Felis catus 75.89 0.00e+00 2273.00
IUUC-Fso-038440 Fusarium solani 23.39 1.00e-34 142.00
IUUC-Gma-043644 Glycine max 30.67 9.00e-102 365.00
IUUC-Ggo-045152 Gorilla gorilla 76.01 0.00e+00 2126.00
IUUC-Hsa-045891 Homo sapiens 75.88 0.00e+00 2151.00
IUUC-Itr-048019 Ictidomys tridecemlineatus 90.04 0.00e+00 1521.00
IUUC-Lch-049669 Latimeria chalumnae 58.98 0.00e+00 999.00
IUUC-Loc-052488 Lepisosteus oculatus 60.02 0.00e+00 1022.00
IUUC-Laf-053992 Loxodonta africana 76.15 0.00e+00 2155.00
IUUC-Mcc-054994 Macaca mulatta 76.52 0.00e+00 2122.00
IUUC-Meu-056815 Macropus eugenii 79.14 0.00e+00 1389.00
IUUC-Mtr-058383 Medicago truncatula 29.40 5.00e-49 188.00
IUUC-Mmr-060693 Microcebus murinus 74.03 0.00e+00 2071.00
IUUC-Mdo-063007 Monodelphis domestica 62.61 0.00e+00 1690.00
IUUC-Mmu-064067 Mus musculus 90.73 0.00e+00 2639.00
IUUC-Mpu-066532 Mustela putorius furo 76.03 0.00e+00 2261.00
IUUC-Mlu-066982 Myotis lucifugus 73.21 0.00e+00 2040.00
IUUC-Nfi-068613 Neosartorya fischeri 22.53 5.00e-31 130.00
IUUC-Nle-070042 Nomascus leucogenys 81.90 0.00e+00 1850.00
IUUC-Opr-070397 Ochotona princeps 73.72 0.00e+00 2142.00
IUUC-Oan-073119 Ornithorhynchus anatinus 66.96 0.00e+00 867.00
IUUC-Ocu-074274 Oryctolagus cuniculus 74.74 0.00e+00 2056.00
IUUC-Oga-088577 Otolemur garnettii 75.78 0.00e+00 2194.00
IUUC-Oar-090117 Ovis aries 73.13 0.00e+00 2033.00
IUUC-Ptr-090553 Pan troglodytes 76.01 0.00e+00 2173.00
IUUC-Pan-092559 Papio anubis 65.85 0.00e+00 969.00
IUUC-Psi-093710 Pelodiscus sinensis 64.47 0.00e+00 1394.00
IUUC-Pab-098510 Pongo abelii 74.86 0.00e+00 2062.00
IUUC-Pop-099155 Populus trichocarpa 32.03 3.00e-99 357.00
IUUC-Pva-102895 Pteropus vampyrus 75.89 0.00e+00 2172.00
IUUC-Sha-107013 Sarcophilus harrisii 63.41 0.00e+00 1739.00
IUUC-Smo-109134 Selaginella moellendorffii 36.77 6.00e-135 475.00
IUUC-Sar-113261 Sorex araneus 70.47 0.00e+00 1992.00
IUUC-Ssc-115317 Sus scrofa 76.17 0.00e+00 2136.00
IUUC-Tsy-118799 Tarsius syrichta 87.75 0.00e+00 837.00
IUUC-Tni-120316 Tetraodon nigroviridis 57.08 0.00e+00 788.00
IUUC-Tca-121475 Theobroma cacao 30.67 4.00e-97 349.00
IUUC-Tre-122008 Trichoderma reesei 23.27 6.00e-32 133.00
IUUC-Tme-127128 Tuber melanosporum 22.90 4.00e-29 124.00
IUUC-Tbe-127555 Tupaia belangeri 89.76 0.00e+00 984.00
IUUC-Ttr-128722 Tursiops truncatus 73.45 0.00e+00 2106.00
IUUC-Vda-129957 Verticillium dahliae 23.83 2.00e-31 131.00
IUUC-Vpa-130392 Vicugna pacos 62.54 3.00e-95 343.00
IUUC-Vvi-131035 Vitis vinifera 33.66 9.00e-106 378.00
IUUC-Xtr-131789 Xenopus tropicalis 59.02 0.00e+00 976.00
Created Date 25-Jun-2017

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