iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ate-010584

Ensembl Protein ID

CADATEAP00010164

UniProt Accession

Q0D0P3; Q0D0P3_ASPTN

Genbank Protein ID

EAU39137.1

Protein Name

Cullin-1

Genbank Nucleotide ID

CH476594

Gene Name

ATEG_00491

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADATEAG00010164	CADATEAT00010164	CADATEAP00010164

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	9.50e-189	628.1	31	665

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 10   lrqesv.kkeyeelytavynlclsk.................vgaklYkklkevleefikqvkkkveesedeqlLktynreWekfreqlkvlr 84
             +e v  k+y+ lytav+n+c+s+                 +g++lYk l e+l +++++v+++ e ++de+lL +y+reW+++++++k+++
   Q: 31   KLEEGVdMKTYMALYTAVHNFCTSQkavgtgsglqahrgahlLGEELYKLLGEYLSHHLAAVNRESEGHSDEALLGFYIREWTRYTTAAKYIN 123
           456889899************************************************************************************ PP
   S: 85   kifayldrtyvkk.....skkvsevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvveslveLslnk.......laiyk 165
           ++f+yl+r++vk+     +k+v++v++L l +w+++++ ++++++++++l+l+e++R+ge+++++ ++++v s+v+L+l++       l++y+
   Q: 124  HLFRYLNRHWVKReidegKKNVYDVYTLHLVKWKDDFFMKVHQKVMDAVLNLVEKQRNGETIEQSQIKSIVDSFVSLGLDEsdstkstLEVYR 216
           ****************9999************************************************************************* PP
   S: 166  esFEakfleatqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesllaelvallrdkktedlsrm 258
             FE++f  at+ +y++es +f++en+v eY+kk+earl ee+ r+  yl++   ++L+ ++  +l++ h e l +e++ ll++++++dl+rm
   Q: 217  FHFEKPFIAATRVYYENESRRFVAENSVVEYMKKAEARLDEEKARVGLYLHPDISKHLTDTCLDVLVTAHSELLRDEFQVLLDNERQDDLARM 309
           ********************************************************************************************* PP
   S: 259  ykLlsrvlngleellkeleshikeqgkaalt...aeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlka..a 346
           y+Llsr+++gl++l+ ++e h++++g+aa++    e ++ +pk+yV+ ll+++ ++q+lv+eaFn + +F+ +ld+a+++fvn+n++ +   +
   Q: 310  YRLLSRIKDGLDPLRAKFEIHVRKAGLAAVEkvaTEGEAFEPKMYVNALLQVHTRYQSLVNEAFNGESEFVRSLDNACREFVNRNKICSSssT 402
           *******************************876666777**********************************************9998889 PP
   S: 347  kspEllAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfq 439
           kspEllA+y D+lL+k+sk ++e ele++l ++++vfkyi++kdvF+k+Y k+LakRL++  s+s++aE s+i+kLke+ g+e+t+kL+rMfq
   Q: 403  KSPELLAKYTDSLLKKGSKAAEESELEEMLVQIMTVFKYIEDKDVFQKFYSKMLAKRLVHVSSVSDDAETSMISKLKEASGFEYTNKLQRMFQ 495
           ********************************************************************************************* PP
   S: 440  dlkvSedlnrqFk....eekenteesesvelsvlvLsagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkaelkk 528
           d+++S+dln+ +k    +  +++  ++ v+ + ++L +g+Wp ++   ++  P+e+ kt e+f++fY +kh+gRkL+W+++l+++e+ka++ k
   Q: 496  DIQISKDLNASYKdwqeKVLDDDDRKKLVDTNFQILGTGFWPLQAPSTDFLAPPEIVKTAERFQNFYFDKHNGRKLTWLWQLCKGEIKANYIK 588
           *************886555667777899****************88888****************************************9977 PP
   S: 529  g...kyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvsskkqvlkkepeskeieeedlfsvNqef 604
           +   +y++qVstfQm +LL+fn+++++ + +++kat l +e L+  l+ L++ k  vl+ +pe+++   +++fs+N +f
   Q: 589  NtkvPYTFQVSTFQMGILLLFNETDTLEYSDIQKATSLAPEILEPNLGILLKAK--VLTISPEGSKPGPGTSFSLNYNF 665
           7778************************************************98..********************998 PP

Organism

Aspergillus terreus

Protein Sequence
(Fasta)

MPAPIPQPPH KDNLDETWTF LEKGIDSVML KLEEGVDMKT YMALYTAVHN FCTSQKAVGT 60
GSGLQAHRGA HLLGEELYKL LGEYLSHHLA AVNRESEGHS DEALLGFYIR EWTRYTTAAK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCGGCCC CAATTCCGCA ACCACCTCAC AAGGATAACC TTGACGAAAC GTAAGTTTCA 60
GCTCGAACGC CCGCGGAGTA TCGCGCGCGA TACCGTCACA AGCCGCTCGA CTAACTGACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0005829--C:cytosol
GO:0043224--C:nuclear SCF ubiquitin ligase complex
GO:1903467--P:negative regulation of mitotic DNA replication initiation
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000358	Aegilops tauschii	30.71	2.00e-97	348.00
IUUC-Aml-002277	Ailuropoda melanoleuca	48.60	0.00e+00	695.00
IUUC-Atr-002822	Amborella trichopoda	31.28	6.00e-96	343.00
IUUC-Apl-003503	Anas platyrhynchos	48.47	2.00e-162	563.00
IUUC-Aca-005030	Anolis carolinensis	43.31	1.00e-148	518.00
IUUC-Ago-007977	Ashbya gossypii	34.21	1.00e-135	475.00
IUUC-Acl-008190	Aspergillus clavatus	90.71	0.00e+00	1375.00
IUUC-Afl-008542	Aspergillus flavus	82.40	0.00e+00	1114.00
IUUC-Afu-009007	Aspergillus fumigatus	88.61	0.00e+00	1287.00
IUUC-Ani-009290	Aspergillus nidulans	86.14	0.00e+00	1368.00
IUUC-Ang-009600	Aspergillus niger	89.72	0.00e+00	1335.00
IUUC-Aor-009978	Aspergillus oryzae	85.99	0.00e+00	1242.00
IUUC-Ame-011861	Astyanax mexicanus	47.63	0.00e+00	667.00
IUUC-Bgr-012209	Blumeria graminis	65.99	0.00e+00	993.00
IUUC-Bta-012878	Bos taurus	48.73	0.00e+00	694.00
IUUC-Bci-013941	Botrytis cinerea	69.46	0.00e+00	1102.00
IUUC-Cel-018294	Caenorhabditis elegans	40.23	2.00e-157	547.00
IUUC-Cja-018965	Callithrix jacchus	47.02	0.00e+00	662.00
IUUC-Cfa-020671	Canis familiaris	48.73	0.00e+00	694.00
IUUC-Cpo-021762	Cavia porcellus	48.73	0.00e+00	695.00
IUUC-Cre-022585	Chlamydomonas reinhardtii	31.95	7.00e-99	353.00
IUUC-Csa-023873	Chlorocebus sabaeus	48.73	0.00e+00	694.00
IUUC-Cin-025547	Ciona intestinalis	44.93	0.00e+00	628.00
IUUC-Csv-026083	Ciona savignyi	45.33	0.00e+00	662.00
IUUC-Cgl-026452	Colletotrichum gloeosporioides	66.62	0.00e+00	1030.00
IUUC-Cne-026919	Cryptococcus neoformans	47.73	0.00e+00	697.00
IUUC-Dre-027875	Danio rerio	47.91	0.00e+00	671.00
IUUC-Dno-028931	Dasypus novemcinctus	48.73	0.00e+00	690.00
IUUC-Dor-030846	Dipodomys ordii	52.39	2.00e-141	494.00
IUUC-Dse-031472	Dothistroma septosporum	66.75	0.00e+00	1034.00
IUUC-Dme-031793	Drosophila melanogaster	44.52	0.00e+00	632.00
IUUC-Ete-033112	Echinops telfairi	45.17	2.00e-71	261.00
IUUC-Eca-034309	Equus caballus	48.73	0.00e+00	694.00
IUUC-Fca-036330	Felis catus	47.47	0.00e+00	668.00
IUUC-Fal-036899	Ficedula albicollis	48.15	2.00e-167	580.00
IUUC-Fox-037705	Fusarium oxysporum	63.01	0.00e+00	966.00
IUUC-Fso-038367	Fusarium solani	64.18	0.00e+00	996.00
IUUC-Gmo-038708	Gadus morhua	47.41	0.00e+00	671.00
IUUC-Ggr-039917	Gaeumannomyces graminis	66.32	0.00e+00	1033.00
IUUC-Gga-041038	Gallus gallus	48.73	0.00e+00	694.00
IUUC-Gac-041820	Gasterosteus aculeatus	47.91	0.00e+00	700.00
IUUC-Ggo-045154	Gorilla gorilla	41.22	1.00e-131	461.00
IUUC-Hsa-046034	Homo sapiens	48.73	0.00e+00	694.00
IUUC-Itr-048285	Ictidomys tridecemlineatus	48.73	0.00e+00	694.00
IUUC-Kpa-049231	Komagataella pastoris	39.09	7.00e-151	526.00
IUUC-Lch-049673	Latimeria chalumnae	48.86	0.00e+00	692.00
IUUC-Loc-052490	Lepisosteus oculatus	48.42	0.00e+00	678.00
IUUC-Lma-053191	Leptosphaeria maculans	66.07	0.00e+00	1042.00
IUUC-Laf-054582	Loxodonta africana	48.73	0.00e+00	694.00
IUUC-Mcc-055162	Macaca mulatta	48.22	0.00e+00	682.00
IUUC-Meu-055904	Macropus eugenii	46.59	2.00e-72	265.00
IUUC-Mor-057035	Magnaporthe oryzae	64.41	0.00e+00	995.00
IUUC-Mpo-057555	Magnaporthe poae	66.19	0.00e+00	1033.00
IUUC-Mla-059021	Melampsora laricipopulina	51.61	0.00e+00	741.00
IUUC-Mga-060078	Meleagris gallopavo	48.73	0.00e+00	694.00
IUUC-Mvi-060519	Microbotryum violaceum	52.06	0.00e+00	764.00
IUUC-Mmr-061312	Microcebus murinus	48.73	0.00e+00	694.00
IUUC-Mdo-062867	Monodelphis domestica	48.48	0.00e+00	690.00
IUUC-Mmu-063336	Mus musculus	48.73	0.00e+00	694.00
IUUC-Mac-065440	Musa acuminata	31.19	5.00e-96	343.00
IUUC-Mpu-066400	Mustela putorius furo	48.15	2.00e-167	580.00
IUUC-Mlu-067800	Myotis lucifugus	48.60	0.00e+00	694.00
IUUC-Nfi-068384	Neosartorya fischeri	88.87	0.00e+00	1321.00
IUUC-Ncr-068965	Neurospora crassa	65.67	0.00e+00	1002.00
IUUC-Nle-069729	Nomascus leucogenys	48.73	0.00e+00	694.00
IUUC-Opr-071197	Ochotona princeps	33.67	1.00e-100	358.00
IUUC-Ont-071729	Oreochromis niloticus	47.72	0.00e+00	679.00
IUUC-Oan-073309	Ornithorhynchus anatinus	48.73	0.00e+00	694.00
IUUC-Ocu-074661	Oryctolagus cuniculus	48.35	0.00e+00	684.00
IUUC-Ola-087422	Oryzias latipes	48.23	0.00e+00	687.00
IUUC-Oga-088130	Otolemur garnettii	48.73	0.00e+00	694.00
IUUC-Oar-089510	Ovis aries	48.05	0.00e+00	657.00
IUUC-Ptr-090665	Pan troglodytes	48.73	0.00e+00	694.00
IUUC-Pan-092218	Papio anubis	48.73	0.00e+00	694.00
IUUC-Psi-093175	Pelodiscus sinensis	48.73	0.00e+00	694.00
IUUC-Pma-094502	Petromyzon marinus	47.33	0.00e+00	670.00
IUUC-Pno-095067	Phaeosphaeria nodorum	68.36	0.00e+00	1082.00
IUUC-Ppa-095864	Physcomitrella patens	30.72	3.00e-91	327.00
IUUC-Pfo-096705	Poecilia formosa	47.72	0.00e+00	701.00
IUUC-Pab-097578	Pongo abelii	48.73	0.00e+00	694.00
IUUC-Pca-100242	Procavia capensis	52.10	1.00e-144	505.00
IUUC-Ppe-101405	Prunus persica	31.42	6.00e-97	346.00
IUUC-Pva-102155	Pteropus vampyrus	42.78	3.00e-163	566.00
IUUC-Pgr-103297	Puccinia graminis	50.58	0.00e+00	750.00
IUUC-Ptt-103706	Puccinia triticina	49.00	2.00e-107	382.00
IUUC-Pte-104257	Pyrenophora teres	67.27	0.00e+00	1068.00
IUUC-Pyt-104795	Pyrenophora triticirepentis	67.40	0.00e+00	1068.00
IUUC-Rno-105939	Rattus norvegicus	48.73	0.00e+00	694.00
IUUC-Sce-106293	Saccharomyces cerevisiae	32.11	6.00e-126	443.00
IUUC-Sha-106949	Sarcophilus harrisii	48.73	0.00e+00	694.00
IUUC-Sja-107737	Schizosaccharomyces japonicus	47.32	0.00e+00	663.00
IUUC-Spo-108280	Schizosaccharomyces pombe	46.86	0.00e+00	672.00
IUUC-Sly-111279	Solanum lycopersicum	31.67	1.00e-96	345.00
IUUC-Stu-112374	Solanum tuberosum	31.66	1.00e-94	338.00
IUUC-Sar-113138	Sorex araneus	36.93	1.00e-126	445.00
IUUC-Sre-114984	Sporisorium reilianum	50.18	0.00e+00	719.00
IUUC-Ssc-115829	Sus scrofa	48.29	0.00e+00	685.00
IUUC-Tgu-116950	Taeniopygia guttata	48.73	0.00e+00	694.00
IUUC-Tru-118558	Takifugu rubripes	47.72	0.00e+00	689.00
IUUC-Tsy-119621	Tarsius syrichta	39.42	3.00e-103	367.00
IUUC-Tni-120460	Tetraodon nigroviridis	47.59	0.00e+00	693.00
IUUC-Tca-121191	Theobroma cacao	30.67	5.00e-97	347.00
IUUC-Tre-122223	Trichoderma reesei	63.86	0.00e+00	948.00
IUUC-Tvi-122539	Trichoderma virens	62.39	0.00e+00	926.00
IUUC-Tme-126926	Tuber melanosporum	67.49	0.00e+00	1052.00
IUUC-Tbe-127369	Tupaia belangeri	52.56	5.00e-89	320.00
IUUC-Ttr-129022	Tursiops truncatus	48.64	1.00e-152	531.00
IUUC-Uma-129341	Ustilago maydis	50.44	0.00e+00	689.00
IUUC-Vda-129857	Verticillium dahliae	65.24	0.00e+00	990.00
IUUC-Vpa-130166	Vicugna pacos	44.48	6.00e-149	519.00
IUUC-Vvi-131423	Vitis vinifera	31.11	2.00e-96	344.00
IUUC-Xtr-131818	Xenopus tropicalis	48.60	0.00e+00	687.00
IUUC-Xma-134206	Xiphophorus maculatus	47.72	0.00e+00	679.00
IUUC-Yli-134486	Yarrowia lipolytica	42.17	2.00e-169	587.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence