iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ani-009500

Ensembl Protein ID

CADANIAP00009164

UniProt Accession

Q5BAI0; C8VP67; Q5BAI0_EMENI

Genbank Protein ID

CBF86880.1; EAA64156.1

Protein Name

Ubiquitin-like activating enzyme (UbaB), putative (AFU_orthologue AFUA_6G10510)

Genbank Nucleotide ID

BN001307; AACD01000040

Gene Name

ANIA_02450; AN2450.2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADANIAG00009164	CADANIAT00009164	CADANIAP00009164

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.10e-108	362.3	14	411

Active Site

Position(s)	Description	Evidence
176	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 12   aqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleeei 104
           + +++++++vllvGagg+GcEllKnL l+G+g+i+v+D dt+++snlnrqFLfr e+++k+KA va+e ++++ p+ ++ea++ +i++ + ++
   Q: 14   QANRIRESRVLLVGAGGIGCELLKNLLLTGFGEIHVIDLDTIDLSNLNRQFLFRHEHIKKPKAIVAKEVAQKFQPSARIEAYHANIKDSKFDV 106
           4589****************************************************************************************9 PP
   S: 105  vFfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa..vlfnk 195
            +f +f+vV++aldn++arr+vn +cl+a+vpliesgt+G+ Gqv+vi k +tecy+c+ ++  k++P+ct+++tp+++ h+i+wa  +l+ +
   Q: 107  DWFATFNVVFNALDNLDARRHVNMMCLAADVPLIESGTTGFNGQVQVIKKNVTECYDCNSKEVPKSFPVCTIRSTPSQPIHCIVWAksYLLPE 199
           9***************************************************************************************99999 PP
   S: 196  lleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtkskspfwv.........sfcsn 279
           l+++++ ++e+ + ++ ++  e  +  ++e+++ +e          +++   + +   k ++k f+ di + +++++++          f+++
   Q: 200  LFGTSETDTEEFDYSADADNVEEIENLQREARALKE----------IRQSMGSAEFAQKVFDKVFKEDINRLRGMEDMWtsrkapeplDFKEL 282
           999998888887765544444444433344333222..........34444444444677778888888888888888866666666655555 PP
   S: 280  aealq..vpekvekdeevvkasap.......lylllralerfekkkgrkpgelsfekdddsavdlvtaaanlraeslgiepkldddlikeiag 363
           + +l+  +pe  +kd++v ++s++       l  l ++l++++++++ +p++l f+kdd + +d+vta anlra+ +giep  +++++k++ag
   Q: 283  EGTLStvEPEVSLKDQRVWTVSENlavfkdsLDRLSKRLKTLQSEESGSPAVLVFDKDDVDTLDFVTASANLRATIFGIEP-KSKFDTKQMAG 374
           5555555455555555555555555555555889999********************************************.*********** PP
   S: 364  niipaiattnavvgGlaaqEviKvvsgkfeplknffl 400
           niipaiattna+ +Gl++++++Kv++g++++ k +fl
   Q: 375  NIIPAIATTNAMTAGLCVLQALKVLKGDYDHAKMVFL 411
           *******************************998776 PP

Organism

Aspergillus nidulans

Protein Sequence
(Fasta)

MTRDTYLKRS LGTQANRIRE SRVLLVGAGG IGCELLKNLL LTGFGEIHVI DLDTIDLSNL 60
NRQFLFRHEH IKKPKAIVAK EVAQKFQPSA RIEAYHANIK DSKFDVDWFA TFNVVFNALD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAAGTTGC CCGATTGACA CTGATGAGGA ACACATCTAT CTGACCTTAG CCATTATTAG 60
AGATAACCGA GGGGAGGTTC AGGCTGTCGG TTCGTCATTC TTTCATCTAC CAACCTCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR028077--UAE_UbL_dom
IPR019572--UBA_E1_Cys
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF00899--ThiF
PF14732--UAE_UbL
PF10585--UBA_e1_thiolCys

Gene Ontology

GO:0019948--F:SUMO activating enzyme activity
GO:0016925--P:protein sumoylation

KEGG

ani:AN2450.2

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000112	Aegilops tauschii	43.45	1.00e-104	372.00
IUUC-Aml-001662	Ailuropoda melanoleuca	44.38	5.00e-108	383.00
IUUC-Atr-002636	Amborella trichopoda	40.32	4.00e-109	387.00
IUUC-Apl-003369	Anas platyrhynchos	43.24	2.00e-98	350.00
IUUC-Aca-004490	Anolis carolinensis	44.82	3.00e-93	334.00
IUUC-Aly-006359	Arabidopsis lyrata	40.88	2.00e-98	351.00
IUUC-Ath-007667	Arabidopsis thaliana	41.45	3.00e-102	364.00
IUUC-Ago-007844	Ashbya gossypii	42.78	2.00e-99	355.00
IUUC-Acl-008270	Aspergillus clavatus	73.74	0.00e+00	863.00
IUUC-Afl-008674	Aspergillus flavus	74.56	0.00e+00	943.00
IUUC-Afu-008883	Aspergillus fumigatus	70.32	0.00e+00	877.00
IUUC-Ang-009535	Aspergillus niger	76.95	0.00e+00	925.00
IUUC-Aor-010223	Aspergillus oryzae	75.97	0.00e+00	920.00
IUUC-Ate-010282	Aspergillus terreus	69.97	0.00e+00	816.00
IUUC-Ame-011736	Astyanax mexicanus	45.27	3.00e-114	404.00
IUUC-Bgr-012166	Blumeria graminis	61.51	2.00e-178	617.00
IUUC-Bta-012589	Bos taurus	44.49	2.00e-109	387.00
IUUC-Bci-013802	Botrytis cinerea	61.59	0.00e+00	672.00
IUUC-Bdi-014697	Brachypodium distachyon	43.79	4.00e-105	373.00
IUUC-Bol-016315	Brassica oleracea	41.37	1.00e-101	362.00
IUUC-Bra-017009	Brassica rapa	41.36	2.00e-101	361.00
IUUC-Cel-018708	Caenorhabditis elegans	38.36	5.00e-98	350.00
IUUC-Cja-019120	Callithrix jacchus	44.00	1.00e-106	379.00
IUUC-Cfa-021061	Canis familiaris	44.49	5.00e-109	386.00
IUUC-Cpo-021842	Cavia porcellus	44.00	1.00e-106	379.00
IUUC-Csa-024104	Chlorocebus sabaeus	44.00	8.00e-107	379.00
IUUC-Cho-024332	Choloepus hoffmanni	45.05	6.00e-93	332.00
IUUC-Cin-025363	Ciona intestinalis	43.37	2.00e-100	358.00
IUUC-Cgl-026419	Colletotrichum gloeosporioides	57.94	0.00e+00	632.00
IUUC-Cne-026888	Cryptococcus neoformans	55.94	4.00e-90	323.00
IUUC-Cme-027315	Cyanidioschyzon merolae	34.07	4.00e-61	227.00
IUUC-Dre-028420	Danio rerio	44.85	2.00e-112	398.00
IUUC-Dno-030041	Dasypus novemcinctus	44.00	4.00e-107	380.00
IUUC-Dse-031504	Dothistroma septosporum	49.04	7.00e-163	565.00
IUUC-Dme-031771	Drosophila melanogaster	61.05	1.00e-62	232.00
IUUC-Ete-033037	Echinops telfairi	41.80	2.00e-96	344.00
IUUC-Eca-033774	Equus caballus	43.45	1.00e-101	362.00
IUUC-Eeu-035074	Erinaceus europaeus	38.61	1.00e-62	232.00
IUUC-Fca-036508	Felis catus	43.66	3.00e-102	364.00
IUUC-Fal-036813	Ficedula albicollis	43.35	3.00e-99	354.00
IUUC-Fox-038056	Fusarium oxysporum	57.66	0.00e+00	665.00
IUUC-Fso-038223	Fusarium solani	55.57	0.00e+00	632.00
IUUC-Gmo-038526	Gadus morhua	50.11	3.00e-101	361.00
IUUC-Ggr-039767	Gaeumannomyces graminis	63.27	5.00e-173	599.00
IUUC-Gga-040981	Gallus gallus	43.21	1.00e-102	365.00
IUUC-Gac-041437	Gasterosteus aculeatus	46.57	4.00e-113	400.00
IUUC-Gma-043041	Glycine max	42.32	6.00e-110	389.00
IUUC-Ggo-045358	Gorilla gorilla	44.87	8.00e-105	372.00
IUUC-Hsa-046068	Homo sapiens	44.00	8.00e-107	379.00
IUUC-Hvu-047646	Hordeum vulgare	43.70	3.00e-104	370.00
IUUC-Itr-047887	Ictidomys tridecemlineatus	43.80	9.00e-107	379.00
IUUC-Kpa-049301	Komagataella pastoris	57.41	4.00e-47	180.00
IUUC-Lch-049565	Latimeria chalumnae	46.42	4.00e-117	413.00
IUUC-Lpe-050884	Leersia perrieri	43.07	6.00e-105	373.00
IUUC-Loc-052493	Lepisosteus oculatus	44.19	4.00e-116	410.00
IUUC-Lma-053117	Leptosphaeria maculans	63.45	0.00e+00	625.00
IUUC-Laf-054518	Loxodonta africana	44.06	9.00e-108	382.00
IUUC-Mcc-055334	Macaca mulatta	44.20	5.00e-107	380.00
IUUC-Mor-057137	Magnaporthe oryzae	60.59	3.00e-159	553.00
IUUC-Mpo-057449	Magnaporthe poae	56.94	2.00e-180	624.00
IUUC-Mtr-058045	Medicago truncatula	42.09	3.00e-112	397.00
IUUC-Mla-058864	Melampsora laricipopulina	45.86	2.00e-101	361.00
IUUC-Mga-059422	Meleagris gallopavo	41.05	2.00e-79	288.00
IUUC-Mvi-060536	Microbotryum violaceum	48.42	4.00e-127	446.00
IUUC-Mmr-061161	Microcebus murinus	43.16	3.00e-105	374.00
IUUC-Mdo-061802	Monodelphis domestica	43.28	7.00e-106	376.00
IUUC-Mmu-064357	Mus musculus	44.96	1.00e-114	405.00
IUUC-Mac-065475	Musa acuminata	40.84	5.00e-105	373.00
IUUC-Mpu-066895	Mustela putorius furo	44.38	5.00e-109	386.00
IUUC-Mlu-067862	Myotis lucifugus	44.51	7.00e-111	392.00
IUUC-Nfi-068385	Neosartorya fischeri	74.47	0.00e+00	908.00
IUUC-Ncr-068885	Neurospora crassa	56.83	0.00e+00	667.00
IUUC-Nle-069524	Nomascus leucogenys	43.60	3.00e-104	370.00
IUUC-Opr-071038	Ochotona princeps	44.62	3.00e-114	404.00
IUUC-Ont-071719	Oreochromis niloticus	43.31	1.00e-116	411.00
IUUC-Oan-072877	Ornithorhynchus anatinus	44.38	2.00e-98	351.00
IUUC-Ocu-074080	Oryctolagus cuniculus	44.02	3.00e-107	380.00
IUUC-Oba-075936	Oryza barthii	43.36	2.00e-105	375.00
IUUC-Obr-076841	Oryza brachyantha	43.94	3.00e-106	377.00
IUUC-Ogl-077686	Oryza glaberrima	43.01	6.00e-107	379.00
IUUC-Ogu-078597	Oryza glumaepatula	41.98	8.00e-103	365.00
IUUC-Oin-079791	Oryza indica	43.36	2.00e-105	375.00
IUUC-Olo-081009	Oryza longistaminata	43.36	2.00e-105	375.00
IUUC-Ome-081327	Oryza meridionalis	39.56	1.00e-98	352.00
IUUC-Oni-082334	Oryza nivara	42.25	3.00e-103	367.00
IUUC-Opu-083447	Oryza punctata	43.72	2.00e-105	374.00
IUUC-Oru-084977	Oryza rufipogon	43.36	1.00e-105	375.00
IUUC-Osa-086160	Oryza sativa	46.48	3.00e-99	353.00
IUUC-Ola-087415	Oryzias latipes	43.26	1.00e-112	398.00
IUUC-Olu-087850	Ostreococcus lucimarinus	43.35	2.00e-105	374.00
IUUC-Oga-088434	Otolemur garnettii	43.40	6.00e-106	376.00
IUUC-Oar-089872	Ovis aries	43.57	1.00e-101	361.00
IUUC-Ptr-091212	Pan troglodytes	44.00	8.00e-107	379.00
IUUC-Pan-092708	Papio anubis	62.15	4.00e-63	233.00
IUUC-Psi-093703	Pelodiscus sinensis	40.75	3.00e-99	353.00
IUUC-Pno-094953	Phaeosphaeria nodorum	56.21	3.00e-180	623.00
IUUC-Ppa-095963	Physcomitrella patens	42.86	2.00e-103	367.00
IUUC-Pfo-097515	Poecilia formosa	50.57	1.00e-114	405.00
IUUC-Pab-097951	Pongo abelii	41.26	4.00e-81	293.00
IUUC-Pop-099703	Populus trichocarpa	39.06	5.00e-94	336.00
IUUC-Pca-100426	Procavia capensis	45.80	3.00e-110	390.00
IUUC-Ppe-101152	Prunus persica	39.72	3.00e-110	390.00
IUUC-Pva-102792	Pteropus vampyrus	42.74	1.00e-99	355.00
IUUC-Pgr-103592	Puccinia graminis	42.67	3.00e-119	420.00
IUUC-Ptt-103805	Puccinia triticina	41.85	5.00e-100	357.00
IUUC-Pte-104215	Pyrenophora teres	59.25	0.00e+00	687.00
IUUC-Pyt-104634	Pyrenophora triticirepentis	59.76	0.00e+00	695.00
IUUC-Rno-106117	Rattus norvegicus	45.07	2.00e-115	408.00
IUUC-Sce-106177	Saccharomyces cerevisiae	42.08	4.00e-99	353.00
IUUC-Sha-107006	Sarcophilus harrisii	44.60	8.00e-106	375.00
IUUC-Sja-107967	Schizosaccharomyces japonicus	54.85	2.00e-149	520.00
IUUC-Spo-108020	Schizosaccharomyces pombe	51.44	4.00e-139	486.00
IUUC-Ssl-108509	Sclerotinia sclerotiorum	61.18	0.00e+00	673.00
IUUC-Smo-109264	Selaginella moellendorffii	45.00	2.00e-100	357.00
IUUC-Sit-110581	Setaria italica	43.60	4.00e-105	374.00
IUUC-Sly-111870	Solanum lycopersicum	41.68	2.00e-106	377.00
IUUC-Stu-112283	Solanum tuberosum	41.42	2.00e-106	378.00
IUUC-Sar-113432	Sorex araneus	58.78	9.00e-41	159.00
IUUC-Sbi-114075	Sorghum bicolor	44.23	2.00e-107	381.00
IUUC-Sre-114926	Sporisorium reilianum	46.09	3.00e-131	460.00
IUUC-Ssc-116281	Sus scrofa	62.15	3.00e-62	229.00
IUUC-Tgu-117247	Taeniopygia guttata	43.24	3.00e-99	353.00
IUUC-Tru-118075	Takifugu rubripes	44.75	6.00e-101	359.00
IUUC-Tsy-119398	Tarsius syrichta	62.90	3.00e-41	161.00
IUUC-Tni-120771	Tetraodon nigroviridis	38.79	9.00e-86	309.00
IUUC-Tca-121651	Theobroma cacao	42.35	5.00e-110	390.00
IUUC-Tre-122224	Trichoderma reesei	57.66	8.00e-171	592.00
IUUC-Tvi-122634	Trichoderma virens	60.18	2.00e-168	584.00
IUUC-Tae-125665	Triticum aestivum	43.17	1.00e-103	368.00
IUUC-Tur-126417	Triticum urartu	41.27	2.00e-103	367.00
IUUC-Tme-127016	Tuber melanosporum	60.04	6.00e-174	602.00
IUUC-Tbe-127678	Tupaia belangeri	62.90	5.00e-41	160.00
IUUC-Ttr-128598	Tursiops truncatus	41.97	2.00e-100	358.00
IUUC-Uma-129612	Ustilago maydis	46.99	2.00e-117	414.00
IUUC-Vda-129811	Verticillium dahliae	57.90	7.00e-177	612.00
IUUC-Vpa-130732	Vicugna pacos	38.39	3.00e-72	264.00
IUUC-Vvi-130832	Vitis vinifera	40.91	2.00e-103	367.00
IUUC-Xtr-132823	Xenopus tropicalis	44.60	6.00e-97	346.00
IUUC-Xma-133552	Xiphophorus maculatus	50.34	3.00e-114	404.00
IUUC-Yli-134666	Yarrowia lipolytica	47.65	3.00e-114	404.00
IUUC-Zma-135547	Zea mays	43.79	2.00e-106	378.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence