iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096174

Ensembl Protein ID

ENSPFOP00000001291.1

UniProt Accession

A0A087X688; A0A087X688_POEFO

Genbank Protein ID

ENSPFOP00000001291

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01002972

Gene Name

UBE2K (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000001355.1	ENSPFOT00000001294.1	ENSPFOP00000001291.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.10e-46	156.8	8	146
UBD/Alpha-Helix/UBA	1.50e-09	38.2	161	199
UBD/UBC-like/UBD_UBC	6.80e-72	240.6	8	149

Active Site

Position(s)	Description	Evidence
92	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkel...ekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsi 85
           R+k+e+ke+   e++++++i++++vde ++te++ +i Gp+dtpYegg ++lei++pe+YPf+PPkv+f+tki+hPn+++  G++Cl+i
   Q: 8    RIKREFKEVlksEETSKNQIKVDLVDE-NFTELKGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVtGAICLDI 95
           7888888873335556699********.9***************************************************99******* PP
   S: 86   lkeeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           lk  ++W +a+++++vlls+q+lla ++p++p+++ +a+++k+n+e++k++++
   Q: 96   LK--DQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTAK 146
           *9..*********************************************9986 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyLld 40
           e++ k+++l++MGF++++++ aL + ++++e A+e+Ll+
   Q: 161  EYTRKIDKLCAMGFEKNAVIVALSSKSWDVETATELLLS 199
           57889********************************97 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeea...qisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpnins.ngsicldil 85
           rik+e+k++l++ee+   qi++dlvd++++el+++iagppd+pyegg+++l+ik+p++ypf+ppkv+fitki+hpni+s +g+icldil
   Q: 8    RIKREFKEVLKSEETsknQIKVDLVDENFTELKGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSvTGAICLDIL 96
           8*************9999*********************************************************************** PP
   S: 86   rsqwsaaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           ++qw+aa+tl++vllsl++lla+aepddp++a++a++yk+++e++k++a++w+
   Q: 97   KDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTAKLWS 149
           ****************************************************5 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MANIAVQRIK REFKEVLKSE ETSKNQIKVD LVDENFTELK GEIAGPPDTP YEGGRYQLEI 60
KIPETYPFNP PKVRFITKIW HPNISSVTGA ICLDILKDQW AAAMTLRTVL LSLQALLAAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTAAGCTTC CCACCAACTT CGGGGACCGA CGAGACAGGA GGCGAACAAC GTTCCAGCTG 60
TTATTTTTGA GATCGTGTAT TTTAAAAAAG TCAGGAGCTG TTGTCGGTAA AAGCAGCTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50030--UBA
PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00627--UBA
PF00179--UQ_con

SMART

SM00165--UBA

Gene Ontology

GO:0005524--F:ATP binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000621	Aegilops tauschii	51.55	4.00e-28	118.00
IUUC-Ago-007714	Ashbya gossypii	45.70	1.00e-38	152.00
IUUC-Cel-018353	Caenorhabditis elegans	53.77	2.00e-58	218.00
IUUC-Cre-022987	Chlamydomonas reinhardtii	48.98	2.00e-41	162.00
IUUC-Cin-025598	Ciona intestinalis	61.73	2.00e-56	211.00
IUUC-Csv-025831	Ciona savignyi	63.27	1.00e-54	206.00
IUUC-Cne-027068	Cryptococcus neoformans	41.38	9.00e-41	159.00
IUUC-Fso-038296	Fusarium solani	42.00	2.00e-35	142.00
IUUC-Gmo-039135	Gadus morhua	98.50	3.00e-108	384.00
IUUC-Ggr-039768	Gaeumannomyces graminis	40.10	5.00e-26	111.00
IUUC-Gac-041503	Gasterosteus aculeatus	99.00	3.00e-109	387.00
IUUC-Kpa-049297	Komagataella pastoris	50.33	2.00e-34	139.00
IUUC-Mor-056946	Magnaporthe oryzae	37.93	1.00e-23	103.00
IUUC-Mvi-060346	Microbotryum violaceum	41.50	8.00e-34	137.00
IUUC-Ont-071595	Oreochromis niloticus	99.00	3.00e-109	387.00
IUUC-Ola-087043	Oryzias latipes	99.00	3.00e-109	387.00
IUUC-Sce-106394	Saccharomyces cerevisiae	43.68	2.00e-36	145.00
IUUC-Sre-115046	Sporisorium reilianum	40.20	5.00e-37	147.00
IUUC-Tru-118196	Takifugu rubripes	86.67	3.00e-104	370.00
IUUC-Tni-119667	Tetraodon nigroviridis	98.50	6.00e-109	386.00
IUUC-Tme-127024	Tuber melanosporum	50.32	1.00e-38	153.00
IUUC-Vda-129947	Verticillium dahliae	36.71	3.00e-31	128.00
IUUC-Xma-134165	Xiphophorus maculatus	99.50	2.00e-109	387.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence