iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	miRTarBase	microRNA	TRANSFAC
RepTar	RAID2
Protein-protein Interaction
IID	PINA	HINT	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	dbPTM
PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.70e-30	103.8	120	151
UBD/Beta-Prp	2.00e-50	172.8	41	210

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDl 30
           gHt  v+ ++f  ++ ++vsG+dD t+k+WD+
   Q: 120  GHTKAVHTVDFtaDNYHVVSGADDYTVKLWDI 151
           8***********64499**************6 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlsls 101
           +++v+fsp+ ++  +  ++++i ++   ++  ++++s  +++ ++ +f +dg++lv gseD++++++d++ + +++ ++gh++ v +++
   Q: 41   VSKVDFSPQLPYNYAVTASSRIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDINGRAPLRQFEGHTKAVHTVD 129
           78899*9998887777788********************************************************************** PP
   S: 102  fspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           f ++++++vsG +d t+++wd+++ +++  t+++h++ v+c + ++ + +l+v+Gs+D tv+++d +t+k +   +  h ++v+
   Q: 130  FTADNYHVVSGADDYTVKLWDIPNSKEIL-TFKEHSDYVRCGCASKLNpDLFVTGSYDHTVKIFDARTNKNVLCVE--HGQPVE 210
           *****************************.**************************************99776553..555555 PP

Organism

Mus musculus

Functional Description
(View)

Involved in nucleolar processing of pre-18S ribosomal RNA.

Protein Sequence
(Fasta)

MAGYKPVAIQ TYPVLGEKIT QDTLYWNNYK TPVQIKEFGA VSKVDFSPQL PYNYAVTASS 60
RIHIYGRYSQ EPVKTFSRFK DTAYCATFRQ DGQLLVAGSE DGVVQLFDIN GRAPLRQFEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGACTGTCCG CGTGATTTTG AGCGAGTGCT GCAGAGCGGT ATGCTGTAGG GAGCTGGCGA 60
AGTCTGGGGA GTCGTCCTGG GGATCGGTGC CTCGGTGGAC CCTCGGGGCC CCGCGGAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR018983--U3_snoRNA-assocProt_15_C
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF09384--UTP15_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005783--C:endoplasmic reticulum
GO:0001650--C:fibrillar center
GO:0005730--C:nucleolus
GO:0003723--F:RNA binding
GO:0006364--P:rRNA processing

KEGG

mmu:105372

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002117	Ailuropoda melanoleuca	91.45	0.00e+00	931.00
IUUC-Atr-003068	Amborella trichopoda	32.82	3.00e-66	246.00
IUUC-Apl-003926	Anas platyrhynchos	67.68	0.00e+00	698.00
IUUC-Aca-004271	Anolis carolinensis	70.21	0.00e+00	722.00
IUUC-Aly-005525	Arabidopsis lyrata	34.33	4.00e-63	235.00
IUUC-Ath-006954	Arabidopsis thaliana	34.12	2.00e-63	236.00
IUUC-Ago-007973	Ashbya gossypii	32.09	1.00e-67	250.00
IUUC-Acl-008287	Aspergillus clavatus	31.82	2.00e-56	213.00
IUUC-Afl-008504	Aspergillus flavus	30.93	6.00e-65	241.00
IUUC-Afu-008983	Aspergillus fumigatus	31.69	1.00e-53	204.00
IUUC-Ani-009315	Aspergillus nidulans	32.58	8.00e-64	238.00
IUUC-Ang-009690	Aspergillus niger	29.98	1.00e-61	230.00
IUUC-Aor-010181	Aspergillus oryzae	30.93	6.00e-65	241.00
IUUC-Ate-010498	Aspergillus terreus	31.31	3.00e-59	223.00
IUUC-Ame-011814	Astyanax mexicanus	57.17	8.00e-174	603.00
IUUC-Bgr-012273	Blumeria graminis	31.46	2.00e-72	266.00
IUUC-Bta-013068	Bos taurus	89.21	0.00e+00	929.00
IUUC-Bci-013930	Botrytis cinerea	31.05	2.00e-73	270.00
IUUC-Bdi-014876	Brachypodium distachyon	31.59	2.00e-64	240.00
IUUC-Bol-015366	Brassica oleracea	33.73	2.00e-65	243.00
IUUC-Bra-017589	Brassica rapa	32.54	2.00e-62	233.00
IUUC-Cel-018159	Caenorhabditis elegans	29.54	2.00e-61	230.00
IUUC-Cja-019139	Callithrix jacchus	92.04	0.00e+00	909.00
IUUC-Cfa-020742	Canis familiaris	86.07	0.00e+00	896.00
IUUC-Cpo-021707	Cavia porcellus	90.72	0.00e+00	945.00
IUUC-Cre-022665	Chlamydomonas reinhardtii	40.82	1.00e-91	330.00
IUUC-Csa-023024	Chlorocebus sabaeus	90.08	0.00e+00	932.00
IUUC-Cho-024487	Choloepus hoffmanni	88.45	1.00e-137	483.00
IUUC-Cin-025294	Ciona intestinalis	45.49	5.00e-134	471.00
IUUC-Cgl-026388	Colletotrichum gloeosporioides	30.06	4.00e-42	165.00
IUUC-Cne-026945	Cryptococcus neoformans	39.52	1.00e-83	303.00
IUUC-Cme-027108	Cyanidioschyzon merolae	30.63	6.00e-56	211.00
IUUC-Dre-028316	Danio rerio	58.67	2.00e-176	611.00
IUUC-Dno-028985	Dasypus novemcinctus	89.50	0.00e+00	908.00
IUUC-Dor-030219	Dipodomys ordii	78.52	2.00e-166	578.00
IUUC-Dse-031495	Dothistroma septosporum	29.55	2.00e-48	186.00
IUUC-Dme-031769	Drosophila melanogaster	38.20	1.00e-85	310.00
IUUC-Ete-032630	Echinops telfairi	80.75	0.00e+00	737.00
IUUC-Eca-033816	Equus caballus	90.86	0.00e+00	934.00
IUUC-Eeu-034840	Erinaceus europaeus	78.39	0.00e+00	702.00
IUUC-Fca-035751	Felis catus	89.69	0.00e+00	936.00
IUUC-Fal-036733	Ficedula albicollis	68.55	0.00e+00	739.00
IUUC-Fox-037743	Fusarium oxysporum	30.78	2.00e-65	243.00
IUUC-Fso-038395	Fusarium solani	30.98	7.00e-67	248.00
IUUC-Gmo-038803	Gadus morhua	63.77	0.00e+00	643.00
IUUC-Ggr-040092	Gaeumannomyces graminis	30.99	2.00e-60	227.00
IUUC-Gga-040714	Gallus gallus	68.00	0.00e+00	744.00
IUUC-Gac-042640	Gasterosteus aculeatus	61.48	0.00e+00	665.00
IUUC-Gma-044192	Glycine max	32.87	1.00e-70	260.00
IUUC-Ggo-045616	Gorilla gorilla	86.99	0.00e+00	923.00
IUUC-Hsa-046720	Homo sapiens	87.93	0.00e+00	870.00
IUUC-Itr-048796	Ictidomys tridecemlineatus	90.66	0.00e+00	936.00
IUUC-Kpa-049291	Komagataella pastoris	30.82	6.00e-66	244.00
IUUC-Lch-049729	Latimeria chalumnae	73.86	0.00e+00	736.00
IUUC-Lpe-051141	Leersia perrieri	32.40	7.00e-65	241.00
IUUC-Loc-051756	Lepisosteus oculatus	70.72	0.00e+00	738.00
IUUC-Lma-053083	Leptosphaeria maculans	30.38	9.00e-64	238.00
IUUC-Laf-054067	Loxodonta africana	86.17	0.00e+00	880.00
IUUC-Mcc-055096	Macaca mulatta	90.08	0.00e+00	932.00
IUUC-Meu-056604	Macropus eugenii	73.90	0.00e+00	738.00
IUUC-Mor-057186	Magnaporthe oryzae	31.76	7.00e-63	234.00
IUUC-Mtr-058346	Medicago truncatula	33.01	4.00e-67	248.00
IUUC-Mla-059116	Melampsora laricipopulina	36.09	3.00e-84	305.00
IUUC-Mga-060038	Meleagris gallopavo	63.37	3.00e-150	524.00
IUUC-Mvi-060272	Microbotryum violaceum	33.83	1.00e-81	297.00
IUUC-Mmr-060877	Microcebus murinus	89.00	0.00e+00	922.00
IUUC-Mdo-062168	Monodelphis domestica	80.13	0.00e+00	781.00
IUUC-Mac-065330	Musa acuminata	34.08	5.00e-54	205.00
IUUC-Mpu-065704	Mustela putorius furo	91.29	0.00e+00	938.00
IUUC-Mlu-067640	Myotis lucifugus	89.17	0.00e+00	929.00
IUUC-Nfi-068589	Neosartorya fischeri	31.69	4.00e-54	206.00
IUUC-Ncr-068769	Neurospora crassa	30.42	2.00e-63	236.00
IUUC-Nle-069105	Nomascus leucogenys	84.01	0.00e+00	855.00
IUUC-Opr-070203	Ochotona princeps	87.07	0.00e+00	941.00
IUUC-Ont-072054	Oreochromis niloticus	67.07	0.00e+00	700.00
IUUC-Oan-073624	Ornithorhynchus anatinus	73.71	0.00e+00	680.00
IUUC-Ocu-074326	Oryctolagus cuniculus	89.19	0.00e+00	923.00
IUUC-Obr-076038	Oryza brachyantha	32.90	2.00e-65	243.00
IUUC-Ogl-077463	Oryza glaberrima	30.54	5.00e-60	225.00
IUUC-Ogu-078631	Oryza glumaepatula	31.01	2.00e-66	246.00
IUUC-Oin-079242	Oryza indica	30.74	5.00e-61	228.00
IUUC-Olo-080652	Oryza longistaminata	29.30	5.00e-56	211.00
IUUC-Ome-081109	Oryza meridionalis	31.91	1.00e-57	219.00
IUUC-Oni-082187	Oryza nivara	30.74	5.00e-61	228.00
IUUC-Opu-083995	Oryza punctata	31.90	2.00e-59	223.00
IUUC-Oru-084962	Oryza rufipogon	32.02	2.00e-57	216.00
IUUC-Osa-086201	Oryza sativa	32.02	2.00e-57	216.00
IUUC-Ola-087115	Oryzias latipes	66.00	0.00e+00	691.00
IUUC-Olu-087842	Ostreococcus lucimarinus	34.64	2.00e-72	266.00
IUUC-Oga-088204	Otolemur garnettii	89.11	0.00e+00	921.00
IUUC-Oar-089297	Ovis aries	89.42	0.00e+00	926.00
IUUC-Ptr-090953	Pan troglodytes	90.47	0.00e+00	937.00
IUUC-Pan-092451	Papio anubis	86.13	0.00e+00	908.00
IUUC-Psi-092999	Pelodiscus sinensis	74.55	0.00e+00	764.00
IUUC-Pma-094304	Petromyzon marinus	46.71	8.00e-130	457.00
IUUC-Pno-095060	Phaeosphaeria nodorum	32.29	2.00e-64	239.00
IUUC-Ppa-095433	Physcomitrella patens	38.33	9.00e-98	350.00
IUUC-Pfo-096433	Poecilia formosa	63.89	0.00e+00	664.00
IUUC-Pab-098677	Pongo abelii	89.49	0.00e+00	929.00
IUUC-Pop-099329	Populus trichocarpa	33.95	1.00e-64	240.00
IUUC-Pca-100444	Procavia capensis	78.96	0.00e+00	743.00
IUUC-Ppe-101318	Prunus persica	32.13	1.00e-76	280.00
IUUC-Pva-102162	Pteropus vampyrus	79.57	0.00e+00	835.00
IUUC-Pgr-103329	Puccinia graminis	40.68	1.00e-66	247.00
IUUC-Ptt-103837	Puccinia triticina	31.53	3.00e-75	276.00
IUUC-Pte-104133	Pyrenophora teres	31.49	4.00e-67	249.00
IUUC-Pyt-104675	Pyrenophora triticirepentis	31.30	1.00e-66	247.00
IUUC-Rno-105004	Rattus norvegicus	95.27	0.00e+00	1005.00
IUUC-Sce-106443	Saccharomyces cerevisiae	30.31	3.00e-66	246.00
IUUC-Sha-107199	Sarcophilus harrisii	78.68	0.00e+00	838.00
IUUC-Sja-107670	Schizosaccharomyces japonicus	38.96	3.00e-97	348.00
IUUC-Spo-108125	Schizosaccharomyces pombe	38.16	5.00e-92	331.00
IUUC-Ssl-108534	Sclerotinia sclerotiorum	30.86	1.00e-71	264.00
IUUC-Smo-109588	Selaginella moellendorffii	37.03	2.00e-93	336.00
IUUC-Sit-110043	Setaria italica	30.59	4.00e-48	185.00
IUUC-Stu-112396	Solanum tuberosum	35.36	2.00e-83	302.00
IUUC-Sar-113359	Sorex araneus	87.97	9.00e-156	542.00
IUUC-Sre-114995	Sporisorium reilianum	34.57	2.00e-85	310.00
IUUC-Ssc-115397	Sus scrofa	89.11	0.00e+00	927.00
IUUC-Tgu-116834	Taeniopygia guttata	66.03	0.00e+00	739.00
IUUC-Tru-118764	Takifugu rubripes	65.66	0.00e+00	700.00
IUUC-Tsy-119118	Tarsius syrichta	89.69	0.00e+00	934.00
IUUC-Tni-120053	Tetraodon nigroviridis	66.06	0.00e+00	704.00
IUUC-Tca-121842	Theobroma cacao	34.80	5.00e-73	268.00
IUUC-Tre-122172	Trichoderma reesei	32.49	3.00e-69	256.00
IUUC-Tvi-122288	Trichoderma virens	31.78	7.00e-57	214.00
IUUC-Tae-124909	Triticum aestivum	32.49	4.00e-53	202.00
IUUC-Tur-126846	Triticum urartu	31.36	2.00e-30	126.00
IUUC-Tme-127164	Tuber melanosporum	32.52	7.00e-73	268.00
IUUC-Tbe-127458	Tupaia belangeri	89.67	0.00e+00	870.00
IUUC-Ttr-128680	Tursiops truncatus	88.82	0.00e+00	896.00
IUUC-Uma-129508	Ustilago maydis	34.94	3.00e-85	309.00
IUUC-Vda-129696	Verticillium dahliae	35.63	5.00e-53	202.00
IUUC-Vpa-130820	Vicugna pacos	89.50	0.00e+00	920.00
IUUC-Vvi-131126	Vitis vinifera	34.27	6.00e-86	311.00
IUUC-Xtr-131826	Xenopus tropicalis	69.82	0.00e+00	738.00
IUUC-Xma-133373	Xiphophorus maculatus	65.07	0.00e+00	680.00
IUUC-Yli-134432	Yarrowia lipolytica	32.32	6.00e-72	265.00
IUUC-Zma-135241	Zea mays	30.86	5.00e-58	218.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence