iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-042341

UUCD1 version

UUC-GaA-00155

Ensembl Protein ID

ENSGACP00000004310.1

UniProt Accession

G3NG55; G3NG55_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000003286.1	ENSGACT00000004324.1	ENSGACP00000004310.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.90e-63	215.3	689	1013

Active Site

Position(s)	Description	Evidence
983	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEe.gldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrll 88
           ++lkk l v + ++   +d    +r+ ++ l++++ +p  g f+++++++  ++p+ ++     e   +F ++G+l+g+al ++ ++
   Q: 689  QELKKPLAVYYDEDPkLTDV--NKRDLFHHLFRKMVSPGSGTFMFNDSETLAWFPSTANE----EDKTHFFLFGVLCGLALWNNSVI 769
           56777777777665414444..89******************************999886....455666688************** PP
   S: 89   dlplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvk 175
            lp++ +++k+llg++ +ledl+e+ p++ ksl+ i++++  + e ++ld  f   +  +   ++  ++ ++ n   +  N++e+v+
   Q: 770  HLPFPLVLFKKLLGVEPTLEDLKEFSPDVGKSLQCILNYD--EDELMKLDGDFICYKA-FAPLTSSFIINSSLNFYLNLPNRKEFVD 853
           ***************************************6..6667778888876665.55555555******************** PP
   S: 176  lvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerk 262
           ++v++ ++ +++  +e+f++Gf +v++ + ++lF++eel+ l+ G++ +++ +lk++t  +  +  +s++ q+Fwev+ e+++++rk
   Q: 854  AYVSHAFNASVEAVFEEFKRGFFRVCDRDPVTLFRPEELQGLLVGQDVYEWAKLKQNTVWDL-WIGSSNK-QMFWEVFDELTEDQRK 938
           ************************************************************99.4444444.68************** PP
   S: 263  afLqFvTgssrlPlgGfaelkprlfvirk....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           +fL F+Tgs r+P+ G+++++ +++++++    ++ d+++P++ TC + L LP Ysskei++ekL+ A ++++ F+
   Q: 939  DFLWFLTGSRRVPILGMDQVR-MKVQVPQlkngQGYDQHFPEALTCHSILYLPLYSSKEIMREKLTEALKTERVFS 1013
           *********************.556666679999999********************************9988776 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

VSQVACGGQH SVALTKGGQV YTWGRNSRGQ LGLGRSETCI DSPQRLGGLS ALPLVLVAAG 60
GEQSFALSVS GAVFGWGRND RGQLGLGDTA VSVSCPRRPL EAFCNIPVSQ VACGSQHSVA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGTCTCAGG TTGCTTGTGG GGGCCAGCAC TCAGTGGCCC TCACCAAAGG TACAGTGTTC 60
CGCTAATCTA CAGGCTGAAT CAATATGGCT GTTTTTCAGC CGTACAAGAT ACGTTTGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens

PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3

Pfam

PF00632--HECT
PF00415--RCC1

PRINTS

PR00633--RCCNDNSATION

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cre-023014	Chlamydomonas reinhardtii	40.26	9.00e-53	200.00
IUUC-Dre-028471	Danio rerio	39.31	3.00e-143	502.00
IUUC-Ont-072212	Oreochromis niloticus	54.03	0.00e+00	1004.00
IUUC-Ola-086390	Oryzias latipes	51.23	0.00e+00	816.00
IUUC-Pfo-096958	Poecilia formosa	54.63	0.00e+00	882.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence