iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-124946

Ensembl Protein ID

TRIAE_CS42_2AL_TGACv1_096450_AA0319230.1

UniProt Accession

A0A1D5TGK4; A0A1D5TGK4_WHEAT

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_2AL_TGACv1_096450_AA0319230	TRIAE_CS42_2AL_TGACv1_096450_AA0319230.1	TRIAE_CS42_2AL_TGACv1_096450_AA0319230.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.00e-23	82.2	291	328
E3 adaptor/Cullin RING/APC_C/CDC20	6.60e-123	412.5	156	467

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           gH+ +v++l++  s++ l+sG++D+ +++WD++   ++
   Q: 291  GHSQEVCGLKWsgSGRQLASGGNDNLLHIWDVSMASST 328
           8**********976699**************9766655 PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 2    ekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtll 69
           ++ ldap+l dd+ylnLldW+s nvl++aLg++vylw+a++g+ s+l  + e++  vtsvsw ++g+ +
   Q: 156  DRTLDAPDLVDDYYLNLLDWGSANVLSIALGNTVYLWDAASGSTSELVTVdEDDGPVTSVSWAPDGQNI 224
           689***********************************************455557************* PP
   S: 70   avGtkkgeveiyDveekkkvrtltg.hsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqaha 137
           a+G ++++v+i+D ++++ +rtl+g h +rvg+L+Wn+ +l++G+ dg+i+ +dvr++++ ++t+++h+
   Q: 225  AIGLNSSAVQIWDSSSNRLLRTLQGvHESRVGSLAWNKSILTAGGMDGKIVNNDVRIRDHAVQTYRGHS 293
           ***********************664899**************************************** PP
   S: 138  qevCGlkwnedaklLasGGnDnsvsvwdassse.........PlkkfkehkaavkaiawsPwqkslLas 197
           qevCGlkw+ ++++LasGGnDn +++wd s  +          l+++++h+aavka+aw+P+q++lLas
   Q: 294  QEVCGLKWSGSGRQLASGGNDNLLHIWDVSMASstqsagrtqWLHRMEDHSAAVKALAWCPFQSNLLAS 362
           ****************************9876656778887788999********************** PP
   S: 198  GGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgh 266
           GGG++Drcikfwnt tga+l+++dtgsqvc llw k+ +el+s+hGf++n++tlwkyps++k+ael+gh
   Q: 363  GGGANDRCIKFWNTHTGACLNSVDTGSQVCALLWNKNDRELLSSHGFTQNQLTLWKYPSMAKMAELNGH 431
           ********************************************************************* PP
   S: 267  eaRvlslalspdgeaivtaagDetlrfwklfdkkka 302
           ++Rvl +a spdg ++++aa+Detlrfw++f++ ++
   Q: 432  TSRVLFMAQSPDGCTVASAAADETLRFWNVFSEAPK 467
           *******************************98765 PP

Organism

Triticum aestivum

Protein Sequence
(Fasta)

MDAGSDMMSP EKSGRRGARP PLREAGLTPS MPPLHEPGSR PRPYMPSLCS TPRNPAVKCY 60
GDRFIPDRSA MDMDMAHYLL TEPRKDRKNG ATPSPAKEAY RKLLAEKLLN NCTRILAFRN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAACGGCTA TATCATTTAC ACCCTTCCAT CTTTGCCTCC CCCCATACCA CTATTTCCAC 60
CCCACGGATC CTCCAAGAAC TCCCCGCCCC GCCCCCGCAC AGAACCAACT CCGCCGCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cre-022701	Chlamydomonas reinhardtii	51.18	1.00e-115	410.00
IUUC-Gac-041431	Gasterosteus aculeatus	43.63	3.00e-97	349.00
IUUC-Tru-118184	Takifugu rubripes	43.84	3.00e-91	329.00
IUUC-Tur-126018	Triticum urartu	99.34	0.00e+00	909.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence