iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066781

Ensembl Protein ID

ENSMPUP00000002410.1

UniProt Accession

M3XTL0; M3XTL0_MUSPF

Genbank Protein ID

ENSMPUP00000002410

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01039146

Gene Name

HLTF

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000002436.1	ENSMPUT00000002459.1	ENSMPUP00000002410.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.70e-07	29.6	758	799

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           CaiCl+++   p+++ C Hvf++ C+ q      ++++++++CPlCr
   Q: 758  CAICLDSLTV-PVITHCAHVFCKPCIcQV----IQNEQPHAKCPLCR 799
           ********88.999************444....599**********8 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MSWMFKRDPV WKYLQTVQYG THGNFPRLSY PTFFPRFEFQ DIIPPDDFLT SDEELDSVLF 60
GTLRGHVVGL RYYTGVVNNN EMVALQREPN NPYDKNAIKV NNVNGNQVGH LKKDLAAALA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGAACCCT GTAAATCTAA ATTCCAATTA AAGTCTCCTG AATTCGTTGT GTCTCATAGA 60
TTCGCTAGTG ACACTTAAAA TGAATAGTTT GAGGGCAATC ACCCGAGGTT CACCCCAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR014905--HIRAN
IPR030065--HLTF
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00271--Helicase_C
PF08797--HIRAN
PF00176--SNF2_N

SMART

SM00487--DEXDc
SM00490--HELICc
SM00910--HIRAN
SM00184--RING

Gene Ontology

GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003723--F:RNA binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0006301--P:postreplication repair
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000167	Aegilops tauschii	38.59	1.00e-109	390.00
IUUC-Aml-001237	Ailuropoda melanoleuca	98.02	0.00e+00	1931.00
IUUC-Atr-003058	Amborella trichopoda	38.09	6.00e-107	382.00
IUUC-Apl-003679	Anas platyrhynchos	30.39	7.00e-36	146.00
IUUC-Aca-004994	Anolis carolinensis	66.43	0.00e+00	1252.00
IUUC-Aly-005898	Arabidopsis lyrata	42.59	1.00e-119	424.00
IUUC-Ath-007559	Arabidopsis thaliana	42.59	2.00e-120	427.00
IUUC-Ago-007997	Ashbya gossypii	33.06	2.00e-78	287.00
IUUC-Acl-008053	Aspergillus clavatus	36.71	3.00e-79	290.00
IUUC-Afl-008697	Aspergillus flavus	36.87	2.00e-85	311.00
IUUC-Afu-008767	Aspergillus fumigatus	34.88	5.00e-85	309.00
IUUC-Ani-009435	Aspergillus nidulans	35.28	3.00e-84	306.00
IUUC-Ang-009874	Aspergillus niger	33.85	8.00e-81	295.00
IUUC-Aor-010130	Aspergillus oryzae	37.36	4.00e-87	315.00
IUUC-Ate-010582	Aspergillus terreus	34.33	1.00e-78	288.00
IUUC-Ame-011743	Astyanax mexicanus	60.93	0.00e+00	656.00
IUUC-Bgr-012147	Blumeria graminis	34.48	1.00e-83	304.00
IUUC-Bta-013391	Bos taurus	93.76	0.00e+00	1886.00
IUUC-Bci-013741	Botrytis cinerea	34.01	5.00e-84	306.00
IUUC-Bdi-014267	Brachypodium distachyon	40.43	1.00e-118	420.00
IUUC-Bol-016075	Brassica oleracea	42.23	6.00e-123	435.00
IUUC-Bra-017057	Brassica rapa	42.86	1.00e-122	433.00
IUUC-Cja-019685	Callithrix jacchus	93.66	0.00e+00	1944.00
IUUC-Cfa-020485	Canis familiaris	97.42	0.00e+00	1920.00
IUUC-Cpo-021361	Cavia porcellus	88.59	0.00e+00	1081.00
IUUC-Cre-022824	Chlamydomonas reinhardtii	29.35	7.00e-64	239.00
IUUC-Csa-023894	Chlorocebus sabaeus	93.86	0.00e+00	1889.00
IUUC-Cho-024891	Choloepus hoffmanni	95.77	0.00e+00	752.00
IUUC-Csv-026168	Ciona savignyi	29.31	5.00e-51	196.00
IUUC-Cgl-026606	Colletotrichum gloeosporioides	33.11	2.00e-87	317.00
IUUC-Cne-026829	Cryptococcus neoformans	36.85	1.00e-92	334.00
IUUC-Cme-027110	Cyanidioschyzon merolae	33.80	2.00e-90	327.00
IUUC-Dre-027867	Danio rerio	62.43	0.00e+00	723.00
IUUC-Dno-029517	Dasypus novemcinctus	93.26	0.00e+00	1854.00
IUUC-Dor-030590	Dipodomys ordii	86.32	0.00e+00	718.00
IUUC-Dse-031471	Dothistroma septosporum	30.84	2.00e-76	281.00
IUUC-Dme-031815	Drosophila melanogaster	30.42	6.00e-53	202.00
IUUC-Ete-032421	Echinops telfairi	75.35	0.00e+00	994.00
IUUC-Eca-034058	Equus caballus	95.22	0.00e+00	1866.00
IUUC-Eeu-034597	Erinaceus europaeus	76.91	0.00e+00	1454.00
IUUC-Fca-035390	Felis catus	97.62	0.00e+00	1907.00
IUUC-Fox-037751	Fusarium oxysporum	38.15	2.00e-88	320.00
IUUC-Fso-038179	Fusarium solani	34.07	1.00e-86	315.00
IUUC-Gmo-038544	Gadus morhua	55.14	0.00e+00	677.00
IUUC-Ggr-039735	Gaeumannomyces graminis	31.61	2.00e-73	271.00
IUUC-Gga-040472	Gallus gallus	32.35	5.00e-38	153.00
IUUC-Gac-042401	Gasterosteus aculeatus	52.23	0.00e+00	980.00
IUUC-Gma-044315	Glycine max	37.91	6.00e-101	362.00
IUUC-Ggo-045628	Gorilla gorilla	93.10	0.00e+00	1860.00
IUUC-Hsa-045930	Homo sapiens	93.66	0.00e+00	1885.00
IUUC-Hvu-047747	Hordeum vulgare	38.14	5.00e-109	389.00
IUUC-Itr-048493	Ictidomys tridecemlineatus	92.99	0.00e+00	1874.00
IUUC-Kpa-049087	Komagataella pastoris	34.62	1.00e-84	308.00
IUUC-Lch-050617	Latimeria chalumnae	61.04	0.00e+00	1122.00
IUUC-Lpe-051724	Leersia perrieri	42.19	7.00e-122	431.00
IUUC-Loc-052785	Lepisosteus oculatus	67.10	0.00e+00	775.00
IUUC-Lma-052956	Leptosphaeria maculans	30.10	1.00e-76	281.00
IUUC-Laf-054309	Loxodonta africana	91.08	0.00e+00	1752.00
IUUC-Mcc-055493	Macaca mulatta	93.18	0.00e+00	1867.00
IUUC-Meu-056270	Macropus eugenii	77.49	0.00e+00	926.00
IUUC-Mor-056943	Magnaporthe oryzae	36.33	2.00e-92	333.00
IUUC-Mpo-057407	Magnaporthe poae	32.00	7.00e-79	289.00
IUUC-Mtr-058172	Medicago truncatula	42.28	1.00e-115	410.00
IUUC-Mla-059170	Melampsora laricipopulina	32.34	2.00e-74	273.00
IUUC-Mga-059553	Meleagris gallopavo	31.91	8.00e-38	152.00
IUUC-Mvi-060365	Microbotryum violaceum	33.11	1.00e-83	304.00
IUUC-Mmr-061043	Microcebus murinus	92.15	0.00e+00	1762.00
IUUC-Mdo-062919	Monodelphis domestica	80.65	0.00e+00	1498.00
IUUC-Mmu-064338	Mus musculus	83.61	0.00e+00	1701.00
IUUC-Mac-065666	Musa acuminata	34.89	7.00e-89	322.00
IUUC-Mlu-068076	Myotis lucifugus	92.98	0.00e+00	1846.00
IUUC-Nfi-068386	Neosartorya fischeri	34.70	2.00e-83	303.00
IUUC-Ncr-068858	Neurospora crassa	36.67	1.00e-89	324.00
IUUC-Nle-069947	Nomascus leucogenys	93.56	0.00e+00	1887.00
IUUC-Opr-070388	Ochotona princeps	83.04	0.00e+00	1674.00
IUUC-Ont-071782	Oreochromis niloticus	61.08	0.00e+00	670.00
IUUC-Oan-073331	Ornithorhynchus anatinus	80.41	0.00e+00	1374.00
IUUC-Ocu-074705	Oryctolagus cuniculus	93.25	0.00e+00	1801.00
IUUC-Oba-075881	Oryza barthii	41.82	1.00e-119	424.00
IUUC-Obr-076344	Oryza brachyantha	41.30	5.00e-116	411.00
IUUC-Ogl-076957	Oryza glaberrima	41.82	1.00e-119	424.00
IUUC-Ogu-078648	Oryza glumaepatula	41.04	4.00e-114	405.00
IUUC-Oin-079449	Oryza indica	41.26	3.00e-115	409.00
IUUC-Olo-080721	Oryza longistaminata	41.26	1.00e-115	410.00
IUUC-Ome-081579	Oryza meridionalis	40.96	1.00e-115	410.00
IUUC-Oni-083054	Oryza nivara	41.26	3.00e-115	409.00
IUUC-Opu-083706	Oryza punctata	41.44	5.00e-116	412.00
IUUC-Oru-085259	Oryza rufipogon	41.26	3.00e-115	409.00
IUUC-Osa-085568	Oryza sativa	41.53	4.00e-102	365.00
IUUC-Ola-086830	Oryzias latipes	51.55	0.00e+00	927.00
IUUC-Olu-087669	Ostreococcus lucimarinus	29.33	1.00e-56	215.00
IUUC-Oga-088120	Otolemur garnettii	87.28	0.00e+00	1641.00
IUUC-Oar-089293	Ovis aries	93.77	0.00e+00	1900.00
IUUC-Ptr-091418	Pan troglodytes	93.56	0.00e+00	1887.00
IUUC-Pan-092579	Papio anubis	93.19	0.00e+00	1429.00
IUUC-Psi-093626	Pelodiscus sinensis	71.20	0.00e+00	1244.00
IUUC-Pno-094841	Phaeosphaeria nodorum	38.65	3.00e-88	319.00
IUUC-Ppa-095291	Physcomitrella patens	46.79	5.00e-143	501.00
IUUC-Pfo-096540	Poecilia formosa	52.21	0.00e+00	978.00
IUUC-Pab-098010	Pongo abelii	93.76	0.00e+00	1887.00
IUUC-Pop-099320	Populus trichocarpa	36.38	2.00e-107	383.00
IUUC-Pca-100648	Procavia capensis	79.09	0.00e+00	1524.00
IUUC-Ppe-102077	Prunus persica	41.57	2.00e-102	367.00
IUUC-Pva-102896	Pteropus vampyrus	91.42	0.00e+00	907.00
IUUC-Pgr-103403	Puccinia graminis	31.11	4.00e-73	270.00
IUUC-Ptt-103966	Puccinia triticina	31.69	2.00e-72	267.00
IUUC-Pte-104242	Pyrenophora teres	32.17	3.00e-81	297.00
IUUC-Pyt-104728	Pyrenophora triticirepentis	31.86	4.00e-79	290.00
IUUC-Rno-106130	Rattus norvegicus	83.81	0.00e+00	1703.00
IUUC-Sce-106159	Saccharomyces cerevisiae	32.38	9.00e-78	285.00
IUUC-Sha-107221	Sarcophilus harrisii	81.85	0.00e+00	1523.00
IUUC-Sja-107985	Schizosaccharomyces japonicus	34.99	2.00e-89	323.00
IUUC-Spo-108305	Schizosaccharomyces pombe	30.76	9.00e-81	295.00
IUUC-Ssl-108388	Sclerotinia sclerotiorum	34.96	1.00e-86	314.00
IUUC-Smo-109629	Selaginella moellendorffii	43.69	2.00e-129	457.00
IUUC-Sit-109770	Setaria italica	41.59	8.00e-117	414.00
IUUC-Sly-111908	Solanum lycopersicum	38.22	8.00e-108	385.00
IUUC-Stu-112600	Solanum tuberosum	37.70	4.00e-107	382.00
IUUC-Sar-113719	Sorex araneus	93.03	0.00e+00	1738.00
IUUC-Sbi-114616	Sorghum bicolor	36.30	9.00e-105	375.00
IUUC-Sre-114938	Sporisorium reilianum	29.07	4.00e-74	273.00
IUUC-Ssc-116186	Sus scrofa	95.94	0.00e+00	1946.00
IUUC-Tru-117768	Takifugu rubripes	51.19	0.00e+00	930.00
IUUC-Tsy-118957	Tarsius syrichta	86.24	0.00e+00	1674.00
IUUC-Tni-120618	Tetraodon nigroviridis	52.84	0.00e+00	981.00
IUUC-Tca-121146	Theobroma cacao	37.89	2.00e-108	387.00
IUUC-Tre-121896	Trichoderma reesei	35.23	1.00e-93	338.00
IUUC-Tvi-122597	Trichoderma virens	33.72	7.00e-89	322.00
IUUC-Tae-123773	Triticum aestivum	42.31	1.00e-109	390.00
IUUC-Tur-125999	Triticum urartu	39.05	8.00e-109	388.00
IUUC-Tme-126953	Tuber melanosporum	33.69	8.00e-88	318.00
IUUC-Tbe-127612	Tupaia belangeri	84.12	0.00e+00	823.00
IUUC-Ttr-128243	Tursiops truncatus	91.16	0.00e+00	1399.00
IUUC-Uma-129441	Ustilago maydis	29.24	1.00e-74	275.00
IUUC-Vda-129933	Verticillium dahliae	36.99	7.00e-83	302.00
IUUC-Vpa-130672	Vicugna pacos	95.45	0.00e+00	1773.00
IUUC-Vvi-131204	Vitis vinifera	42.83	2.00e-125	443.00
IUUC-Xtr-132730	Xenopus tropicalis	61.51	0.00e+00	1238.00
IUUC-Xma-133384	Xiphophorus maculatus	52.44	0.00e+00	970.00
IUUC-Yli-134350	Yarrowia lipolytica	31.34	6.00e-75	275.00
IUUC-Zma-134966	Zea mays	43.54	7.00e-128	451.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence