iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-134269

Ensembl Protein ID

ENSXMAP00000013216.1

UniProt Accession

M4AFH2; M4AFH2_XIPMA

Genbank Protein ID

ENSXMAP00000013216

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01030872

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000013142.1	ENSXMAT00000013232.1	ENSXMAP00000013216.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.80e-21	74.8	590	626
UBD/Beta-Prp	4.30e-41	141.1	301	541

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gHtd+ ++l+  ++ + +v++s D+++++WD+ t+ +
   Q: 590  GHTDELWGLDVhPSmDQFVTCSQDKQVHLWDTCTHQP 626
           8*********99777****************987765 PP

UBD/Beta-Prp

   S: 32   gtikvwdvttgkllrslsgheaevtavkfspdgkilvtg.....seD.....rtikvwdlstgkcvhtlk..ghedsvlslsfsp.sgd 107
           + + ++++++ +  r + gh++ v++++ +pd  +++tg     s+D      ++++wd  +  ++h++   + ++ v ++sfs+ +g 
   Q: 301  SVVVLYNTEE-QQQRHYLGHNDDVKCLTVHPDMVTIATGqvagnSKDgkllaPHVRIWDSVSLNTLHVIGmgAFDRAVSCVSFSKsNGG 388
           4455666666.555999***************9999998555556779999999****99988888887765889999*******8777 PP
   S: 108  klvsGsh...drtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtl....tgghtdsvyslsf 188
           +++ + +   d ++ vw++++++ l    +  +++v  +v+hp + nl+v++++ + +++W ++ + l ++     + ++ ++v +++f
   Q: 389  SFLCAVDdanDHILSVWNWQKEKQLA-EVKCSNDSVLAAVFHPMDtNLIVTCGK-SHINFWTMEGNALTKRQglfeKHEKPKYVLCVAF 475
           7777754122678899**********.6666777888999999998******98.679*****9999999988887555778899999* PP
   S: 189  dsngkelvsgsldgtvklwdlqtgecvrtlng.htdnvksvrfspnderlvsgssDgsiriWdlrsg 254
            +ng + ++g+  g + +w    +++ + + g h+  + sv ++++++ +  g++D+ + +Wd   +
   Q: 476  AENG-DAITGDSSGNLYIWAKGGNRISQVVSGaHEGGIFSVCVLKDGTMVSGGGKDRKVALWDHNYR 541
           **98.899************9988887777666***********8888888888********75443 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MWMFMDVGET GSGEGVKTRR RKAKGGRGSP PRAGGAADRD GRGEERGRMS ERIASCGSLC 60
DSTNLLLQYC NNDDTVSASS NMDMEDRVSH LEQRLQLQED EIQLLKAALA DALRRLGYCE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGAAACGGA AGTGGGTCTG TAATAAAAAC GTCGGCTTGC CGCTGGCTGT GAAGCTGGAG 60
CGGGAGAAGC AGAGGCAGCG GAGGCAGGTG AAGGTGTGAA TGTGGATGTT TATGGATGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR005108--HELP
IPR023302--Pept_S9A_N
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005316	Anolis carolinensis	66.25	0.00e+00	1013.00
IUUC-Ame-011647	Astyanax mexicanus	80.24	0.00e+00	1298.00
IUUC-Bta-013267	Bos taurus	62.42	0.00e+00	1006.00
IUUC-Cel-018623	Caenorhabditis elegans	30.70	9.00e-88	318.00
IUUC-Cfa-020267	Canis familiaris	63.35	0.00e+00	1007.00
IUUC-Cre-022931	Chlamydomonas reinhardtii	35.37	2.00e-98	356.00
IUUC-Cin-025784	Ciona intestinalis	54.76	0.00e+00	732.00
IUUC-Dre-028734	Danio rerio	79.54	0.00e+00	1321.00
IUUC-Dme-032093	Drosophila melanogaster	38.32	1.00e-117	417.00
IUUC-Eeu-035302	Erinaceus europaeus	66.58	3.00e-153	535.00
IUUC-Gmo-039389	Gadus morhua	81.81	0.00e+00	1174.00
IUUC-Gac-042643	Gasterosteus aculeatus	86.54	0.00e+00	1385.00
IUUC-Itr-048788	Ictidomys tridecemlineatus	63.12	0.00e+00	999.00
IUUC-Loc-052518	Lepisosteus oculatus	75.06	0.00e+00	1185.00
IUUC-Meu-056664	Macropus eugenii	66.41	0.00e+00	924.00
IUUC-Mmr-060853	Microcebus murinus	64.01	0.00e+00	1012.00
IUUC-Mmu-063860	Mus musculus	63.89	0.00e+00	1015.00
IUUC-Mpu-066043	Mustela putorius furo	63.81	0.00e+00	1008.00
IUUC-Ont-071258	Oreochromis niloticus	91.94	0.00e+00	1446.00
IUUC-Ola-086616	Oryzias latipes	84.39	0.00e+00	1233.00
IUUC-Pan-092082	Papio anubis	63.60	0.00e+00	1013.00
IUUC-Pma-094555	Petromyzon marinus	56.72	0.00e+00	801.00
IUUC-Pfo-096717	Poecilia formosa	97.56	0.00e+00	1548.00
IUUC-Pca-101070	Procavia capensis	59.38	0.00e+00	806.00
IUUC-Rno-105074	Rattus norvegicus	68.28	0.00e+00	946.00
IUUC-Smo-108882	Selaginella moellendorffii	22.16	3.00e-17	84.70
IUUC-Tru-117809	Takifugu rubripes	85.75	0.00e+00	1419.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence