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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Rno-105559
Ensembl Protein ID ENSRNOP00000004217.6
UniProt Accession Q5PQN2; BFAR_RAT
Genbank Protein ID AAH87103.1
Protein Name Bifunctional apoptosis regulator
Genbank Nucleotide ID BC087103
Gene Name Bfar
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000003151.7 ENSRNOT00000004217.7 ENSRNOP00000004217.6
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
TRANSFACRAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 30.43 2.00e-09 60.80 IUUC-Ath-007116
E3 activity/RING/RING 90.22 0.00e+00 853.00 IUUC-Hsa-046155
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Rattus norvegicus
Functional Description
(View)

Functional Description


     Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors (By similarity).
 Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors (By similarity).
Protein Sequence
(Fasta)
MEEPQKNDLS MRGQEEDHPV RSSGPQISVS EFSCHCCYDT LVNPTTLNCG HSFCRHCLAL 60
WWMSSKKTEC PECREKWEGF PKVNILLRDA IEKLFPDAIK MRVEDIQQNN DVVQSLAAFQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105559|E3,RING|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAGCCTAAAG CGGTCTCTTC TCTATGGTTG CAGGAGCTGG TCAGAGTCGG TCCGCAGTCC 60
TACGTTATTT CCGGAAACGA AGCCTGCCGC TTGTCCTCTA CTTCCGCGGG GTCCTGGCGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105559|E3,RING|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0053--Apoptosis
KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0325--Glycoprotein
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001660--SAM
IPR013761--SAM/pointed
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS50105--SAM_DOMAIN
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF00536--SAM_1
SMART

SM00184--RING
SM00454--SAM
Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0043066--P:negative regulation of apoptotic process
GO:1903895--P:negative regulation of IRE1-mediated unfolded protein response
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
KEGG rno:304709
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001856 Ailuropoda melanoleuca 90.00 0.00e+00 787.00
IUUC-Apl-004001 Anas platyrhynchos 76.06 0.00e+00 693.00
IUUC-Aca-005095 Anolis carolinensis 77.39 0.00e+00 679.00
IUUC-Aly-005558 Arabidopsis lyrata 39.29 6.00e-11 62.00
IUUC-Ath-007116 Arabidopsis thaliana 36.90 2.00e-10 60.10
IUUC-Ago-007781 Ashbya gossypii 27.00 5.00e-08 52.40
IUUC-Ame-010623 Astyanax mexicanus 61.01 2.00e-148 518.00
IUUC-Bgr-012267 Blumeria graminis 37.50 2.00e-08 54.30
IUUC-Bta-012806 Bos taurus 88.67 0.00e+00 774.00
IUUC-Bol-015948 Brassica oleracea 35.29 2.00e-10 60.10
IUUC-Bra-017661 Brassica rapa 36.47 1.00e-10 61.20
IUUC-Cel-018107 Caenorhabditis elegans 32.05 1.00e-05 43.90
IUUC-Cja-019478 Callithrix jacchus 87.33 0.00e+00 779.00
IUUC-Cfa-021253 Canis familiaris 91.11 0.00e+00 793.00
IUUC-Cpo-022551 Cavia porcellus 90.44 0.00e+00 791.00
IUUC-Cre-022763 Chlamydomonas reinhardtii 30.77 1.00e-08 52.00
IUUC-Csa-023499 Chlorocebus sabaeus 91.11 0.00e+00 797.00
IUUC-Cho-024665 Choloepus hoffmanni 87.77 1.00e-150 525.00
IUUC-Dno-029161 Dasypus novemcinctus 90.67 0.00e+00 789.00
IUUC-Dor-030580 Dipodomys ordii 91.71 0.00e+00 626.00
IUUC-Ete-032643 Echinops telfairi 82.44 0.00e+00 727.00
IUUC-Eca-034435 Equus caballus 90.67 0.00e+00 788.00
IUUC-Eeu-034787 Erinaceus europaeus 80.13 3.00e-74 272.00
IUUC-Fca-035970 Felis catus 90.67 0.00e+00 790.00
IUUC-Fal-036727 Ficedula albicollis 77.85 0.00e+00 704.00
IUUC-Gmo-039048 Gadus morhua 64.93 4.00e-164 570.00
IUUC-Gga-041098 Gallus gallus 80.87 7.00e-114 403.00
IUUC-Gac-042246 Gasterosteus aculeatus 63.12 8.00e-155 540.00
IUUC-Ggo-045045 Gorilla gorilla 90.67 0.00e+00 792.00
IUUC-Hsa-046155 Homo sapiens 90.22 0.00e+00 788.00
IUUC-Itr-049066 Ictidomys tridecemlineatus 92.89 0.00e+00 805.00
IUUC-Lch-050654 Latimeria chalumnae 75.94 0.00e+00 645.00
IUUC-Loc-051851 Lepisosteus oculatus 68.03 3.00e-176 611.00
IUUC-Laf-053600 Loxodonta africana 91.11 0.00e+00 797.00
IUUC-Mcc-054824 Macaca mulatta 91.33 0.00e+00 798.00
IUUC-Meu-056707 Macropus eugenii 83.22 2.00e-140 491.00
IUUC-Mga-059577 Meleagris gallopavo 77.40 0.00e+00 703.00
IUUC-Mmr-061031 Microcebus murinus 92.44 0.00e+00 806.00
IUUC-Mdo-062696 Monodelphis domestica 84.09 0.00e+00 749.00
IUUC-Mmu-063190 Mus musculus 97.33 0.00e+00 907.00
IUUC-Mac-064489 Musa acuminata 31.40 4.00e-09 55.80
IUUC-Mpu-065811 Mustela putorius furo 89.56 0.00e+00 775.00
IUUC-Mlu-067273 Myotis lucifugus 88.89 0.00e+00 803.00
IUUC-Nle-069226 Nomascus leucogenys 91.11 0.00e+00 795.00
IUUC-Opr-071014 Ochotona princeps 90.00 0.00e+00 792.00
IUUC-Ont-072113 Oreochromis niloticus 64.42 4.00e-163 567.00
IUUC-Oan-072720 Ornithorhynchus anatinus 76.09 3.00e-162 564.00
IUUC-Ocu-073920 Oryctolagus cuniculus 88.39 0.00e+00 732.00
IUUC-Ola-087064 Oryzias latipes 60.13 4.00e-155 540.00
IUUC-Oga-088121 Otolemur garnettii 91.33 0.00e+00 798.00
IUUC-Oar-090404 Ovis aries 88.89 0.00e+00 772.00
IUUC-Ptr-090824 Pan troglodytes 90.44 0.00e+00 792.00
IUUC-Pan-091820 Papio anubis 91.33 0.00e+00 798.00
IUUC-Psi-093328 Pelodiscus sinensis 78.94 0.00e+00 719.00
IUUC-Pma-094362 Petromyzon marinus 54.31 3.00e-131 461.00
IUUC-Ppa-095945 Physcomitrella patens 39.08 8.00e-10 58.20
IUUC-Pfo-096138 Poecilia formosa 63.15 4.00e-161 561.00
IUUC-Pab-097808 Pongo abelii 90.44 0.00e+00 788.00
IUUC-Pca-100409 Procavia capensis 88.44 0.00e+00 743.00
IUUC-Pva-103043 Pteropus vampyrus 91.08 0.00e+00 768.00
IUUC-Sha-107404 Sarcophilus harrisii 71.90 0.00e+00 663.00
IUUC-Ssc-115421 Sus scrofa 85.58 8.00e-147 512.00
IUUC-Tgu-116564 Taeniopygia guttata 78.08 0.00e+00 699.00
IUUC-Tru-118271 Takifugu rubripes 62.09 2.00e-142 498.00
IUUC-Tsy-119122 Tarsius syrichta 94.71 3.00e-105 375.00
IUUC-Tni-120019 Tetraodon nigroviridis 61.48 8.00e-138 483.00
IUUC-Tme-126916 Tuber melanosporum 42.62 1.00e-08 55.80
IUUC-Tbe-127449 Tupaia belangeri 92.00 0.00e+00 803.00
IUUC-Ttr-128570 Tursiops truncatus 90.33 2.00e-172 598.00
IUUC-Vpa-130501 Vicugna pacos 93.78 0.00e+00 724.00
IUUC-Xtr-132154 Xenopus tropicalis 74.55 0.00e+00 677.00
Created Date 25-Jun-2017

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