iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001185

Ensembl Protein ID

ENSAMEP00000013965.1

UniProt Accession

G1M3Q2; G1M3Q2_AILME

Genbank Protein ID

ENSAMEP00000013965

Protein Name

DNA repair protein REV1

Genbank Nucleotide ID

ACTA01072092

Gene Name

REV1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000013212.1	ENSAMET00000014546.1	ENSAMEP00000013965.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBM	9.30e-22	76.1	1012	1040

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBM

   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrqqk 29
           ++sqvDpeVf++LP+e+Q+E++a+++q++
   Q: 1012 AFSQVDPEVFAALPAELQKELKAAYDQRQ 1040
           59*************************98 PP

Organism

Ailuropoda melanoleuca

Functional Description
(View)

Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.

Protein Sequence
(Fasta)

MRRGGWRRRA ESDGWEKWGG YMAAKVQKLE EQFRSDATIQ KDGTSSTIFS GVAIYVNGYT 60
DPSAEELRKL MMLHGGQYHV YYSRSKTTHI IATNLPNAKI KELKGEKVIR PEWIVESIKA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGACGAG GTGGATGGAG GAGGCGAGCT GAAAGTGATG GCTGGGAAAA ATGGGTGTGT 60
TTTAAAAGAA TAAAAATACT TATCTTTAAT TGTCTAGGTA TTTTTTGTTC TTCTTGTAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR025527--DUF4414
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC

PROSITE

PS50172--BRCT
PS50173--UMUC

Pfam

PF16589--BRCT_2
PF14377--DUF4414
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C

SMART

SM00292--BRCT

Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0042276--P:error-prone translesion synthesis
GO:0009411--P:response to UV

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000375	Aegilops tauschii	30.58	3.00e-32	134.00
IUUC-Atr-002915	Amborella trichopoda	33.06	4.00e-84	306.00
IUUC-Apl-004054	Anas platyrhynchos	75.71	0.00e+00	1802.00
IUUC-Aca-004304	Anolis carolinensis	68.20	0.00e+00	1647.00
IUUC-Aly-005696	Arabidopsis lyrata	34.52	3.00e-85	310.00
IUUC-Ath-006893	Arabidopsis thaliana	34.85	1.00e-85	311.00
IUUC-Ago-007722	Ashbya gossypii	29.02	8.00e-41	162.00
IUUC-Acl-008347	Aspergillus clavatus	34.65	3.00e-89	323.00
IUUC-Afl-008444	Aspergillus flavus	33.91	3.00e-88	320.00
IUUC-Afu-008837	Aspergillus fumigatus	32.39	8.00e-87	315.00
IUUC-Ani-009188	Aspergillus nidulans	37.90	5.00e-92	332.00
IUUC-Ang-009866	Aspergillus niger	33.85	9.00e-99	355.00
IUUC-Aor-010107	Aspergillus oryzae	33.91	3.00e-88	320.00
IUUC-Ate-010359	Aspergillus terreus	33.01	3.00e-92	333.00
IUUC-Ame-010664	Astyanax mexicanus	49.93	0.00e+00	1100.00
IUUC-Bgr-012244	Blumeria graminis	31.82	2.00e-83	304.00
IUUC-Bta-013405	Bos taurus	81.98	0.00e+00	1830.00
IUUC-Bci-013849	Botrytis cinerea	31.05	1.00e-88	322.00
IUUC-Bdi-014066	Brachypodium distachyon	37.10	1.00e-85	311.00
IUUC-Bol-015544	Brassica oleracea	35.08	6.00e-87	315.00
IUUC-Bra-017792	Brassica rapa	34.52	2.00e-83	303.00
IUUC-Cel-018148	Caenorhabditis elegans	36.02	3.00e-83	303.00
IUUC-Cja-019742	Callithrix jacchus	76.20	0.00e+00	1512.00
IUUC-Cfa-020112	Canis familiaris	95.06	0.00e+00	2319.00
IUUC-Cpo-022152	Cavia porcellus	83.41	0.00e+00	2103.00
IUUC-Cre-022951	Chlamydomonas reinhardtii	43.15	7.00e-42	165.00
IUUC-Csa-023504	Chlorocebus sabaeus	87.95	0.00e+00	2180.00
IUUC-Cho-024780	Choloepus hoffmanni	65.77	0.00e+00	723.00
IUUC-Cin-025276	Ciona intestinalis	44.44	7.00e-119	421.00
IUUC-Csv-026283	Ciona savignyi	44.72	7.00e-116	411.00
IUUC-Cgl-026726	Colletotrichum gloeosporioides	30.15	2.00e-89	324.00
IUUC-Cne-027079	Cryptococcus neoformans	34.78	2.00e-79	290.00
IUUC-Cme-027346	Cyanidioschyzon merolae	28.22	4.00e-46	180.00
IUUC-Dre-028073	Danio rerio	51.02	0.00e+00	1110.00
IUUC-Dno-030038	Dasypus novemcinctus	83.11	0.00e+00	2022.00
IUUC-Dor-031100	Dipodomys ordii	83.98	0.00e+00	1529.00
IUUC-Dse-031310	Dothistroma septosporum	29.40	2.00e-86	313.00
IUUC-Dme-031991	Drosophila melanogaster	41.30	1.00e-110	394.00
IUUC-Ete-033082	Echinops telfairi	77.83	0.00e+00	1431.00
IUUC-Eca-033471	Equus caballus	90.43	0.00e+00	2191.00
IUUC-Eeu-034993	Erinaceus europaeus	84.40	0.00e+00	1417.00
IUUC-Fca-035367	Felis catus	92.14	0.00e+00	2171.00
IUUC-Fal-036973	Ficedula albicollis	74.16	0.00e+00	1736.00
IUUC-Fox-037677	Fusarium oxysporum	31.53	9.00e-91	328.00
IUUC-Fso-038252	Fusarium solani	31.70	2.00e-93	337.00
IUUC-Gmo-039669	Gadus morhua	61.62	1.00e-173	604.00
IUUC-Ggr-039988	Gaeumannomyces graminis	33.63	2.00e-86	314.00
IUUC-Gga-040423	Gallus gallus	75.79	0.00e+00	1796.00
IUUC-Gac-042134	Gasterosteus aculeatus	48.66	0.00e+00	986.00
IUUC-Gma-042929	Glycine max	31.59	7.00e-112	398.00
IUUC-Ggo-044528	Gorilla gorilla	88.28	0.00e+00	2167.00
IUUC-Hsa-046259	Homo sapiens	88.20	0.00e+00	2140.00
IUUC-Hvu-047139	Hordeum vulgare	35.05	2.00e-57	216.00
IUUC-Itr-048621	Ictidomys tridecemlineatus	87.63	0.00e+00	2143.00
IUUC-Kpa-049169	Komagataella pastoris	29.94	3.00e-61	230.00
IUUC-Lch-050471	Latimeria chalumnae	64.93	0.00e+00	1549.00
IUUC-Lpe-050800	Leersia perrieri	34.05	5.00e-89	323.00
IUUC-Loc-052320	Lepisosteus oculatus	47.90	0.00e+00	945.00
IUUC-Lma-053149	Leptosphaeria maculans	30.36	2.00e-88	320.00
IUUC-Laf-053810	Loxodonta africana	83.41	0.00e+00	1964.00
IUUC-Mcc-055574	Macaca mulatta	88.28	0.00e+00	2122.00
IUUC-Meu-055945	Macropus eugenii	65.40	0.00e+00	1137.00
IUUC-Mor-057195	Magnaporthe oryzae	28.52	2.00e-107	384.00
IUUC-Mpo-057488	Magnaporthe poae	31.99	5.00e-87	316.00
IUUC-Mtr-057955	Medicago truncatula	36.40	8.00e-92	332.00
IUUC-Mla-059027	Melampsora laricipopulina	36.06	9.00e-82	298.00
IUUC-Mga-060156	Meleagris gallopavo	75.87	0.00e+00	1812.00
IUUC-Mvi-060398	Microbotryum violaceum	36.49	1.00e-82	301.00
IUUC-Mmr-061113	Microcebus murinus	89.31	0.00e+00	2157.00
IUUC-Mdo-063001	Monodelphis domestica	82.22	0.00e+00	1977.00
IUUC-Mmu-063180	Mus musculus	81.43	0.00e+00	1981.00
IUUC-Mac-065551	Musa acuminata	37.36	6.00e-54	205.00
IUUC-Mpu-066525	Mustela putorius furo	94.42	0.00e+00	2276.00
IUUC-Mlu-067877	Myotis lucifugus	88.76	0.00e+00	2134.00
IUUC-Nfi-068418	Neosartorya fischeri	32.44	2.00e-86	314.00
IUUC-Ncr-068648	Neurospora crassa	31.88	8.00e-90	325.00
IUUC-Nle-069959	Nomascus leucogenys	88.36	0.00e+00	2154.00
IUUC-Opr-070522	Ochotona princeps	81.77	0.00e+00	1170.00
IUUC-Ont-072293	Oreochromis niloticus	49.04	0.00e+00	799.00
IUUC-Oan-073519	Ornithorhynchus anatinus	78.10	0.00e+00	1902.00
IUUC-Ocu-074492	Oryctolagus cuniculus	83.07	0.00e+00	1920.00
IUUC-Oba-075567	Oryza barthii	32.99	3.00e-91	330.00
IUUC-Obr-076332	Oryza brachyantha	36.95	8.00e-87	315.00
IUUC-Ogl-077348	Oryza glaberrima	32.99	4.00e-91	329.00
IUUC-Ogu-078779	Oryza glumaepatula	30.78	4.00e-118	419.00
IUUC-Oin-079738	Oryza indica	30.42	5.00e-79	289.00
IUUC-Olo-080701	Oryza longistaminata	30.47	3.00e-79	290.00
IUUC-Ome-081708	Oryza meridionalis	32.76	1.00e-87	318.00
IUUC-Oni-082251	Oryza nivara	32.68	3.00e-88	320.00
IUUC-Opu-083528	Oryza punctata	31.51	6.00e-84	305.00
IUUC-Oru-084293	Oryza rufipogon	32.24	5.00e-86	313.00
IUUC-Osa-085549	Oryza sativa	32.99	9.00e-91	328.00
IUUC-Ola-086793	Oryzias latipes	47.36	0.00e+00	1005.00
IUUC-Olu-087786	Ostreococcus lucimarinus	29.49	6.00e-62	231.00
IUUC-Oga-089006	Otolemur garnettii	88.00	0.00e+00	2138.00
IUUC-Oar-089597	Ovis aries	83.27	0.00e+00	1997.00
IUUC-Ptr-091520	Pan troglodytes	88.20	0.00e+00	2136.00
IUUC-Pan-092333	Papio anubis	88.84	0.00e+00	2108.00
IUUC-Psi-094004	Pelodiscus sinensis	78.17	0.00e+00	1884.00
IUUC-Pma-094128	Petromyzon marinus	53.07	9.00e-92	331.00
IUUC-Pno-094849	Phaeosphaeria nodorum	29.37	9.00e-79	288.00
IUUC-Ppa-095714	Physcomitrella patens	31.91	1.00e-93	338.00
IUUC-Pfo-096569	Poecilia formosa	52.43	0.00e+00	811.00
IUUC-Pab-097960	Pongo abelii	87.88	0.00e+00	2130.00
IUUC-Pop-098921	Populus trichocarpa	36.19	2.00e-84	307.00
IUUC-Pca-100509	Procavia capensis	69.54	0.00e+00	1209.00
IUUC-Ppe-101730	Prunus persica	37.18	1.00e-92	334.00
IUUC-Pva-102142	Pteropus vampyrus	87.00	0.00e+00	2081.00
IUUC-Pgr-103446	Puccinia graminis	32.09	2.00e-71	264.00
IUUC-Ptt-103849	Puccinia triticina	30.52	3.00e-74	274.00
IUUC-Pte-104128	Pyrenophora teres	30.48	5.00e-84	306.00
IUUC-Pyt-104754	Pyrenophora triticirepentis	32.02	2.00e-83	304.00
IUUC-Rno-104871	Rattus norvegicus	79.86	0.00e+00	1947.00
IUUC-Sce-106236	Saccharomyces cerevisiae	26.78	7.00e-41	162.00
IUUC-Sha-106962	Sarcophilus harrisii	81.65	0.00e+00	1950.00
IUUC-Sja-107691	Schizosaccharomyces japonicus	32.46	1.00e-66	248.00
IUUC-Spo-108170	Schizosaccharomyces pombe	34.78	3.00e-66	246.00
IUUC-Ssl-108668	Sclerotinia sclerotiorum	35.06	4.00e-88	320.00
IUUC-Smo-109554	Selaginella moellendorffii	37.16	6.00e-86	312.00
IUUC-Sit-110479	Setaria italica	35.57	4.00e-73	270.00
IUUC-Sly-111752	Solanum lycopersicum	37.68	8.00e-91	328.00
IUUC-Sar-113304	Sorex araneus	87.10	0.00e+00	2061.00
IUUC-Sbi-114196	Sorghum bicolor	36.02	2.00e-73	270.00
IUUC-Sre-115151	Sporisorium reilianum	31.27	7.00e-85	309.00
IUUC-Ssc-116104	Sus scrofa	88.37	0.00e+00	2146.00
IUUC-Tgu-117438	Taeniopygia guttata	75.63	0.00e+00	1790.00
IUUC-Tru-118553	Takifugu rubripes	48.15	0.00e+00	1001.00
IUUC-Tsy-119056	Tarsius syrichta	85.18	0.00e+00	1987.00
IUUC-Tni-119933	Tetraodon nigroviridis	47.24	0.00e+00	948.00
IUUC-Tca-121376	Theobroma cacao	35.67	3.00e-86	313.00
IUUC-Tre-121972	Trichoderma reesei	35.17	2.00e-81	297.00
IUUC-Tvi-122342	Trichoderma virens	31.74	5.00e-98	352.00
IUUC-Tae-123898	Triticum aestivum	33.18	3.00e-89	323.00
IUUC-Tur-126735	Triticum urartu	37.04	4.00e-35	143.00
IUUC-Tme-126999	Tuber melanosporum	33.86	3.00e-81	297.00
IUUC-Tbe-127280	Tupaia belangeri	88.57	6.00e-140	492.00
IUUC-Ttr-129104	Tursiops truncatus	87.73	0.00e+00	2096.00
IUUC-Uma-129562	Ustilago maydis	35.28	2.00e-81	297.00
IUUC-Vda-129862	Verticillium dahliae	31.25	1.00e-92	335.00
IUUC-Vpa-130819	Vicugna pacos	83.72	0.00e+00	1088.00
IUUC-Vvi-131111	Vitis vinifera	35.66	3.00e-86	313.00
IUUC-Xtr-132629	Xenopus tropicalis	61.81	0.00e+00	1413.00
IUUC-Xma-134065	Xiphophorus maculatus	51.28	0.00e+00	794.00
IUUC-Yli-134633	Yarrowia lipolytica	33.27	2.00e-65	244.00
IUUC-Zma-135176	Zea mays	32.88	3.00e-88	320.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence