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Tag Content
UUCD2 ID IUUC-Bta-012331
UUCD1 version UUC-BoT-00003
Ensembl Protein ID ENSBTAP00000008938.4
UniProt Accession A0JN69; MARH3_BOVIN
Genbank Protein ID AAI26541.1
Protein Name E3 ubiquitin-protein ligase MARCH3; Membrane-associated RING finger protein 3; Membrane-associated RING-CH protein III; RING-type E3 ubiquitin transferase MARCH3
Genbank Nucleotide ID BC126540
Gene Name MARCH3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSBTAG00000006797.4 ENSBTAT00000008938.4 ENSBTAP00000008938.4
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 98.02 2.00e-146 515.00 IUUC-Hsa-046429
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Bos taurus
Functional Description
(View)

Functional Description


     E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
 E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Protein Sequence
(Fasta)
MTTSRCSHLP EVLPDCTGSA APVVKTVEDC GSLVNGQPQY VMQVSAKDGQ LLSTVVRTLA 60
TQSPFNDRPM CRICHEGSSQ EDLLSPCECT GTLGTIHRSC LEHWLSSSNT SYCELCHFRF 120
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Protein Fasta Sequence


>IUUC-Bta-012331|E3,RING|Bos taurus
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Nucleotide Sequence
(Fasta)
ACCTCCGGAG CCGGGTTGCC TCTACGCGGC TGTCCGCCTC ATTCTCAGAG CAGGTCCGTG 60
AATTGTCGGC GCGCTCCGGG CAGCTGCTGA GCCGGGGCTA CCATCGGGCT TGTCGTGCTC 120
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Nucleotide Fasta Sequence


>IUUC-Bta-012331|E3,RING|Bos taurus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0968--Cytoplasmic vesicle
KW-0254--Endocytosis
KW-0967--Endosome
KW-0472--Membrane
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR033275--MARCH-like
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51292--ZF_RING_CH
Pfam

PF12906--RINGv
SMART

SM00744--RINGv
Gene Ontology

GO:0030659--C:cytoplasmic vesicle membrane
GO:0031901--C:early endosome membrane
GO:0005768--C:endosome
GO:0016021--C:integral component of membrane
GO:0005764--C:lysosome
GO:0016740--F:transferase activity
GO:0008270--F:zinc ion binding
GO:0006897--P:endocytosis
GO:0016567--P:protein ubiquitination
KEGG bta:520348
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000798 Aegilops tauschii 38.89 1.00e-08 54.30
IUUC-Aml-001957 Ailuropoda melanoleuca 98.42 2.00e-148 517.00
IUUC-Atr-002775 Amborella trichopoda 36.36 2.00e-10 58.90
IUUC-Aca-005012 Anolis carolinensis 96.86 2.00e-144 504.00
IUUC-Bdi-014827 Brachypodium distachyon 36.07 8.00e-09 54.30
IUUC-Bol-016602 Brassica oleracea 34.67 1.00e-09 56.60
IUUC-Bra-016861 Brassica rapa 34.67 9.00e-10 57.40
IUUC-Cel-018164 Caenorhabditis elegans 37.17 1.00e-18 87.80
IUUC-Cja-019689 Callithrix jacchus 98.81 6.00e-149 519.00
IUUC-Cfa-020911 Canis familiaris 98.42 2.00e-148 517.00
IUUC-Cpo-022306 Cavia porcellus 97.23 3.00e-145 506.00
IUUC-Cre-022957 Chlamydomonas reinhardtii 37.80 4.00e-08 52.00
IUUC-Csa-024010 Chlorocebus sabaeus 98.02 3.00e-148 516.00
IUUC-Cho-024645 Choloepus hoffmanni 100.00 3.00e-112 396.00
IUUC-Dno-029999 Dasypus novemcinctus 98.81 8.00e-149 518.00
IUUC-Dor-030860 Dipodomys ordii 99.21 4.00e-149 520.00
IUUC-Ete-032571 Echinops telfairi 97.23 1.00e-146 511.00
IUUC-Eca-034097 Equus caballus 99.21 2.00e-149 521.00
IUUC-Eeu-034645 Erinaceus europaeus 99.24 2.00e-74 272.00
IUUC-Fca-036126 Felis catus 97.23 8.00e-147 512.00
IUUC-Fal-036875 Ficedula albicollis 82.21 5.00e-120 423.00
IUUC-Gga-041200 Gallus gallus 95.81 3.00e-121 427.00
IUUC-Ggo-044825 Gorilla gorilla 98.02 9.00e-148 515.00
IUUC-Hsa-046429 Homo sapiens 98.02 9.00e-148 515.00
IUUC-Itr-048087 Ictidomys tridecemlineatus 98.81 6.00e-149 519.00
IUUC-Lch-049917 Latimeria chalumnae 92.09 4.00e-137 479.00
IUUC-Loc-052071 Lepisosteus oculatus 89.33 3.00e-133 467.00
IUUC-Laf-054385 Loxodonta africana 97.63 1.00e-147 514.00
IUUC-Mcc-054854 Macaca mulatta 98.42 1.00e-148 518.00
IUUC-Mtr-057809 Medicago truncatula 35.82 5.00e-10 57.80
IUUC-Mmr-061764 Microcebus murinus 97.83 7.00e-106 375.00
IUUC-Mmu-063185 Mus musculus 98.81 6.00e-149 519.00
IUUC-Mac-064882 Musa acuminata 38.00 9.00e-09 53.90
IUUC-Mpu-066646 Mustela putorius furo 98.42 2.00e-148 517.00
IUUC-Mlu-067494 Myotis lucifugus 98.02 1.00e-147 515.00
IUUC-Nle-069945 Nomascus leucogenys 98.42 1.00e-148 518.00
IUUC-Opr-070431 Ochotona princeps 98.02 2.00e-147 514.00
IUUC-Ocu-074430 Oryctolagus cuniculus 98.81 1.00e-148 518.00
IUUC-Oba-075948 Oryza barthii 32.14 2.00e-09 55.80
IUUC-Obr-076417 Oryza brachyantha 24.50 9.00e-10 57.40
IUUC-Ogl-077439 Oryza glaberrima 32.14 2.00e-09 55.80
IUUC-Ogu-078523 Oryza glumaepatula 31.11 2.00e-09 55.80
IUUC-Olo-080950 Oryza longistaminata 35.29 8.00e-09 54.30
IUUC-Ome-081221 Oryza meridionalis 32.14 2.00e-09 56.20
IUUC-Oni-082096 Oryza nivara 32.14 3.00e-09 55.80
IUUC-Opu-083949 Oryza punctata 33.77 2.00e-09 56.20
IUUC-Oru-085237 Oryza rufipogon 32.14 2.00e-09 55.80
IUUC-Osa-085964 Oryza sativa 32.14 3.00e-09 55.80
IUUC-Oga-088072 Otolemur garnettii 98.02 9.00e-148 515.00
IUUC-Oar-089761 Ovis aries 99.60 8.00e-150 522.00
IUUC-Ptr-090839 Pan troglodytes 98.02 8.00e-148 515.00
IUUC-Pan-092795 Papio anubis 98.42 1.00e-148 518.00
IUUC-Psi-093674 Pelodiscus sinensis 97.23 7.00e-147 512.00
IUUC-Pma-094464 Petromyzon marinus 68.56 3.00e-76 277.00
IUUC-Pab-098050 Pongo abelii 98.42 1.00e-148 518.00
IUUC-Pop-099863 Populus trichocarpa 36.23 1.00e-09 56.60
IUUC-Pca-100548 Procavia capensis 92.09 2.00e-134 471.00
IUUC-Ppe-101927 Prunus persica 38.03 2.00e-09 55.80
IUUC-Pva-103060 Pteropus vampyrus 98.42 3.00e-148 516.00
IUUC-Rno-104870 Rattus norvegicus 99.21 4.00e-149 520.00
IUUC-Sly-110996 Solanum lycopersicum 40.00 1.00e-11 63.50
IUUC-Stu-112782 Solanum tuberosum 40.00 1.00e-11 63.20
IUUC-Sar-113720 Sorex araneus 98.42 4.00e-148 516.00
IUUC-Ssc-116322 Sus scrofa 98.81 6.00e-149 519.00
IUUC-Tsy-119057 Tarsius syrichta 98.81 6.00e-149 519.00
IUUC-Tca-121215 Theobroma cacao 39.68 6.00e-10 57.80
IUUC-Tae-124189 Triticum aestivum 32.93 2.00e-09 56.20
IUUC-Tur-126784 Triticum urartu 39.44 7.00e-09 55.10
IUUC-Tbe-128101 Tupaia belangeri 98.42 3.00e-148 516.00
IUUC-Ttr-128776 Tursiops truncatus 98.42 2.00e-148 518.00
IUUC-Vpa-130717 Vicugna pacos 96.84 4.00e-108 382.00
IUUC-Vvi-131510 Vitis vinifera 42.59 4.00e-09 56.60
Created Date 25-Jun-2017

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