iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-117509

Ensembl Protein ID

ENSTGUP00000001012.1

UniProt Accession

H0YRV3; H0YRV3_TAEGU

Genbank Protein ID

ENSTGUP00000001012

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01057321

Gene Name

SIRT6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000000987.1	ENSTGUT00000001024.1	ENSTGUP00000001012.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UFD/PB1	28.89	2.20e-01	28.50	IUUC-Ots-000022

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

QIFDPPEELE RKVQELAELI RSSSHVVFHT GAGISTASGI PDFRGPNGVW TMEEKGLSPK 60
FDTTFENARP SKTHMALLGL QRVGILKFLI SNRTSEVHIS CERQVDKLAE LHGNMFVEEC 120

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Nucleotide Sequence
(Fasta)

CAGATTTTTG ACCCTCCGGA GGAGCTGGAG CGGAAGGTGC AGGAGCTGGC AGAGCTGATC 60
CGGAGCTCCT CCCATGTGGT GTTCCACACG GGGGCAGGGA TCAGCACGGC CTCGGGCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR029035--DHS-like_NAD/FAD-binding_dom
IPR003000--Sirtuin
IPR026590--Ssirtuin_cat_dom

PROSITE

PS50305--SIRTUIN

Pfam

PF02146--SIR2

Gene Ontology

GO:0005724--C:nuclear telomeric heterochromatin
GO:0005654--C:nucleoplasm
GO:0003682--F:chromatin binding
GO:0003956--F:NAD(P)+-protein-arginine ADP-ribosyltransferase activity
GO:0070403--F:NAD+ binding
GO:0046969--F:NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0003714--F:transcription corepressor activity
GO:0006284--P:base-excision repair
GO:0042593--P:glucose homeostasis
GO:0008285--P:negative regulation of cell proliferation
GO:0046325--P:negative regulation of glucose import
GO:0045820--P:negative regulation of glycolytic process
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:1905555--P:positive regulation blood vessel branching
GO:1902732--P:positive regulation of chondrocyte proliferation
GO:0031940--P:positive regulation of chromatin silencing at telomere
GO:0048146--P:positive regulation of fibroblast proliferation
GO:2000648--P:positive regulation of stem cell proliferation
GO:0032206--P:positive regulation of telomere maintenance
GO:1905549--P:positive regulation of telomeric heterochromatin assembly
GO:1905564--P:positive regulation of vascular endothelial cell proliferation
GO:0006471--P:protein ADP-ribosylation
GO:0031648--P:protein destabilization
GO:0010569--P:regulation of double-strand break repair via homologous recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000756	Aegilops tauschii	32.50	6.70e-01	26.60
IUUC-Cre-022802	Chlamydomonas reinhardtii	33.33	3.30e+00	28.10
IUUC-Fal-037471	Ficedula albicollis	93.39	5.00e-141	493.00
IUUC-Mtr-058557	Medicago truncatula	31.11	3.30e-01	27.70
IUUC-Ocu-073850	Oryctolagus cuniculus	24.37	4.60e-01	28.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence