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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Dme-031704
Ensembl Protein ID FBpp0089374
UniProt Accession O18645; Q9U4G0; O18645_DROME
Genbank Protein ID AAB71397.1; AAB71398.1; AAF45614.1; AAN09043.1; AAS65245.1; ACH92233.1; CAA19653.1
Protein Name Non-specific serine/threonine protein kinase
Genbank Nucleotide ID AF020309; AF020310; AE014298; AE014298; AE014298; BT044168; AL023893
Gene Name AMPKalpha; EG:132E8.2; SNF1A; SNF1A-RA; CG3051; Dmel_CG3051
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0023169 FBtr0070218 FBpp0089374
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDiRefIndexPINA
Protein 3D Structure
PDBMMDB
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/UBA 44.76 2.00e-114 410.00 IUUC-Ath-007014
UBD/Alpha-Helix/UBA 38.26 3.00e-102 367.00 IUUC-Spo-108202
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Drosophila melanogaster
Protein Sequence
(Fasta)
MPQMRAAAAE AVAAGSANGQ PLVKIGHYLL GATLGTGTFG KVKIGEHQIT RVKVAVKILN 60
RQKIKSLDVV GKIRREIQNL KLFRHPHIIK LYQVISTPSD IFMIMEYVSG GELFDYIVKH 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dme-031704|UBD,UBA|Drosophila melanogaster
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTTGGAAGGC AGTGTTGTTG GAAGTGGCAG CGCCTTCCAA TGTCAATTAA ATAAGCAAAA 60
CGCGAAGAAA ACCCAAGCGT AAAGGAGAGT CTCGTTGCCG CGCTCGAATA GAAATCCAGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-031704|UBD,UBA|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
Interpro

IPR032270--AMPK_C
IPR028375--KA1/Ssp2_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
Pfam

PF16579--AdenylateSensor
PF00069--Pkinase
SMART

SM00220--S_TKc
Gene Ontology

GO:0005737--C:cytoplasm
GO:0031588--C:nucleotide-activated protein kinase complex
GO:0005634--C:nucleus
GO:0004679--F:AMP-activated protein kinase activity
GO:0005524--F:ATP binding
GO:0004703--F:G-protein coupled receptor kinase activity
GO:0035174--F:histone serine kinase activity
GO:0004674--F:protein serine/threonine kinase activity
GO:0007411--P:axon guidance
GO:0042595--P:behavioral response to starvation
GO:0042149--P:cellular response to glucose starvation
GO:0009267--P:cellular response to starvation
GO:0048813--P:dendrite morphogenesis
GO:0045197--P:establishment or maintenance of epithelial cell apical/basal polarity
GO:0006629--P:lipid metabolic process
GO:0000278--P:mitotic cell cycle
GO:0045792--P:negative regulation of cell size
GO:0032007--P:negative regulation of TOR signaling
GO:0006909--P:phagocytosis
GO:0042331--P:phototaxis
GO:0006468--P:protein phosphorylation
GO:0001558--P:regulation of cell growth
GO:0044058--P:regulation of digestive system process
GO:0010906--P:regulation of glucose metabolic process
GO:0030730--P:sequestering of triglyceride
GO:0007165--P:signal transduction
KEGG dme:Dmel_CG3051
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000713 Aegilops tauschii 43.88 2.00e-118 418.00
IUUC-Aml-001907 Ailuropoda melanoleuca 56.44 3.00e-168 584.00
IUUC-Atr-002770 Amborella trichopoda 46.08 4.00e-121 427.00
IUUC-Apl-003395 Anas platyrhynchos 57.91 0.00e+00 647.00
IUUC-Aca-004480 Anolis carolinensis 64.16 0.00e+00 663.00
IUUC-Aly-006289 Arabidopsis lyrata 45.25 1.00e-120 425.00
IUUC-Ath-007014 Arabidopsis thaliana 45.17 2.00e-120 425.00
IUUC-Ago-007957 Ashbya gossypii 42.51 1.00e-115 409.00
IUUC-Acl-008103 Aspergillus clavatus 60.22 4.00e-98 351.00
IUUC-Afl-008555 Aspergillus flavus 49.16 2.00e-99 356.00
IUUC-Afu-008949 Aspergillus fumigatus 48.60 1.00e-98 353.00
IUUC-Ani-009408 Aspergillus nidulans 50.73 3.00e-99 355.00
IUUC-Ang-009551 Aspergillus niger 59.71 2.00e-97 349.00
IUUC-Aor-010176 Aspergillus oryzae 49.16 2.00e-99 356.00
IUUC-Ate-010287 Aspergillus terreus 60.22 2.00e-97 349.00
IUUC-Ame-011019 Astyanax mexicanus 59.43 0.00e+00 684.00
IUUC-Bgr-012045 Blumeria graminis 63.67 9.00e-105 373.00
IUUC-Bta-012786 Bos taurus 56.21 2.00e-168 584.00
IUUC-Bci-013774 Botrytis cinerea 62.92 3.00e-104 372.00
IUUC-Bdi-014319 Brachypodium distachyon 43.54 5.00e-120 424.00
IUUC-Bol-016242 Brassica oleracea 46.05 5.00e-124 437.00
IUUC-Bra-016750 Brassica rapa 46.05 4.00e-124 437.00
IUUC-Cel-018518 Caenorhabditis elegans 55.76 0.00e+00 629.00
IUUC-Cja-019386 Callithrix jacchus 59.53 0.00e+00 681.00
IUUC-Cfa-020177 Canis familiaris 55.26 3.00e-165 573.00
IUUC-Cpo-021805 Cavia porcellus 60.20 0.00e+00 682.00
IUUC-Cre-022915 Chlamydomonas reinhardtii 53.89 2.00e-91 328.00
IUUC-Csa-024267 Chlorocebus sabaeus 59.53 0.00e+00 681.00
IUUC-Cho-024859 Choloepus hoffmanni 53.99 2.00e-161 561.00
IUUC-Cin-025550 Ciona intestinalis 57.72 0.00e+00 653.00
IUUC-Csv-026139 Ciona savignyi 57.05 0.00e+00 650.00
IUUC-Cne-027044 Cryptococcus neoformans 49.59 3.00e-102 365.00
IUUC-Cme-027289 Cyanidioschyzon merolae 58.11 1.00e-113 402.00
IUUC-Dre-027749 Danio rerio 60.89 1.00e-174 605.00
IUUC-Dno-030006 Dasypus novemcinctus 56.21 9.00e-168 582.00
IUUC-Dor-030578 Dipodomys ordii 59.02 0.00e+00 676.00
IUUC-Dse-031507 Dothistroma septosporum 63.43 3.00e-105 375.00
IUUC-Ete-033055 Echinops telfairi 54.99 1.00e-171 595.00
IUUC-Eca-034016 Equus caballus 58.14 0.00e+00 645.00
IUUC-Fca-035754 Felis catus 55.08 5.00e-166 577.00
IUUC-Fal-037363 Ficedula albicollis 56.31 9.00e-169 585.00
IUUC-Fox-038073 Fusarium oxysporum 51.90 4.00e-104 371.00
IUUC-Fso-038236 Fusarium solani 51.31 2.00e-100 358.00
IUUC-Gmo-039633 Gadus morhua 60.58 0.00e+00 625.00
IUUC-Ggr-039987 Gaeumannomyces graminis 61.34 8.00e-103 367.00
IUUC-Gga-040546 Gallus gallus 58.61 0.00e+00 679.00
IUUC-Gac-041822 Gasterosteus aculeatus 58.47 0.00e+00 657.00
IUUC-Gma-042712 Glycine max 42.80 1.00e-115 409.00
IUUC-Ggo-045303 Gorilla gorilla 59.53 0.00e+00 682.00
IUUC-Hsa-045746 Homo sapiens 59.53 0.00e+00 682.00
IUUC-Hvu-047406 Hordeum vulgare 43.91 7.00e-121 426.00
IUUC-Itr-048134 Ictidomys tridecemlineatus 59.53 0.00e+00 681.00
IUUC-Kpa-049190 Komagataella pastoris 42.02 2.00e-120 425.00
IUUC-Lch-049623 Latimeria chalumnae 56.72 3.00e-169 587.00
IUUC-Lpe-051392 Leersia perrieri 43.57 2.00e-118 418.00
IUUC-Loc-052928 Lepisosteus oculatus 60.85 0.00e+00 694.00
IUUC-Lma-053054 Leptosphaeria maculans 41.14 3.00e-112 399.00
IUUC-Laf-053459 Loxodonta africana 59.26 0.00e+00 678.00
IUUC-Mcc-055862 Macaca mulatta 59.53 0.00e+00 682.00
IUUC-Mor-057170 Magnaporthe oryzae 40.48 4.00e-106 378.00
IUUC-Mpo-057302 Magnaporthe poae 61.80 6.00e-103 367.00
IUUC-Mtr-058309 Medicago truncatula 59.87 1.00e-112 399.00
IUUC-Mla-059058 Melampsora laricipopulina 62.12 4.00e-99 354.00
IUUC-Mga-059206 Meleagris gallopavo 57.79 0.00e+00 644.00
IUUC-Mvi-060337 Microbotryum violaceum 42.33 9.00e-111 393.00
IUUC-Mmr-061619 Microcebus murinus 59.36 0.00e+00 680.00
IUUC-Mdo-062160 Monodelphis domestica 60.10 0.00e+00 683.00
IUUC-Mmu-063406 Mus musculus 59.46 0.00e+00 679.00
IUUC-Mac-064518 Musa acuminata 42.25 9.00e-114 403.00
IUUC-Mpu-066326 Mustela putorius furo 57.39 0.00e+00 643.00
IUUC-Mlu-067968 Myotis lucifugus 58.19 0.00e+00 637.00
IUUC-Nfi-068493 Neosartorya fischeri 48.60 2.00e-98 352.00
IUUC-Ncr-068665 Neurospora crassa 36.02 1.00e-108 386.00
IUUC-Nle-070158 Nomascus leucogenys 59.53 0.00e+00 682.00
IUUC-Opr-070272 Ochotona princeps 54.90 1.00e-165 575.00
IUUC-Ont-071395 Oreochromis niloticus 58.61 0.00e+00 672.00
IUUC-Oan-073322 Ornithorhynchus anatinus 54.21 4.00e-165 573.00
IUUC-Ocu-074188 Oryctolagus cuniculus 55.08 2.00e-166 578.00
IUUC-Oba-075436 Oryza barthii 43.51 4.00e-118 417.00
IUUC-Obr-076507 Oryza brachyantha 43.62 3.00e-118 417.00
IUUC-Ogl-077718 Oryza glaberrima 46.56 1.00e-117 416.00
IUUC-Ogu-078349 Oryza glumaepatula 60.06 2.00e-115 408.00
IUUC-Oin-079889 Oryza indica 43.31 1.00e-118 419.00
IUUC-Olo-080521 Oryza longistaminata 43.51 4.00e-118 417.00
IUUC-Ome-081630 Oryza meridionalis 43.33 8.00e-118 416.00
IUUC-Oni-082211 Oryza nivara 43.51 2.00e-118 419.00
IUUC-Opu-083617 Oryza punctata 43.61 4.00e-119 420.00
IUUC-Oru-084252 Oryza rufipogon 43.51 4.00e-118 417.00
IUUC-Osa-085548 Oryza sativa 43.51 4.00e-118 417.00
IUUC-Ola-087169 Oryzias latipes 57.67 0.00e+00 667.00
IUUC-Olu-087861 Ostreococcus lucimarinus 57.14 8.00e-112 396.00
IUUC-Oga-088003 Otolemur garnettii 56.38 1.00e-168 585.00
IUUC-Oar-089933 Ovis aries 56.21 2.00e-168 584.00
IUUC-Ptr-090741 Pan troglodytes 59.53 0.00e+00 682.00
IUUC-Pan-092526 Papio anubis 56.38 1.00e-168 585.00
IUUC-Psi-094034 Pelodiscus sinensis 56.38 5.00e-168 583.00
IUUC-Pno-095030 Phaeosphaeria nodorum 64.04 2.00e-105 374.00
IUUC-Ppa-095615 Physcomitrella patens 46.33 2.00e-117 415.00
IUUC-Pfo-096295 Poecilia formosa 58.45 0.00e+00 669.00
IUUC-Pab-098023 Pongo abelii 59.53 0.00e+00 682.00
IUUC-Pop-099781 Populus trichocarpa 47.58 1.00e-119 422.00
IUUC-Pca-101104 Procavia capensis 69.19 2.00e-132 464.00
IUUC-Ppe-101642 Prunus persica 48.01 3.00e-119 421.00
IUUC-Pva-102470 Pteropus vampyrus 59.97 0.00e+00 675.00
IUUC-Pgr-103406 Puccinia graminis 38.84 3.00e-106 378.00
IUUC-Ptt-103713 Puccinia triticina 38.48 2.00e-84 305.00
IUUC-Pte-104259 Pyrenophora teres 64.42 1.00e-107 383.00
IUUC-Pyt-104752 Pyrenophora triticirepentis 42.99 9.00e-113 400.00
IUUC-Rno-104960 Rattus norvegicus 59.36 0.00e+00 681.00
IUUC-Sce-106290 Saccharomyces cerevisiae 39.83 2.00e-116 412.00
IUUC-Sha-107603 Sarcophilus harrisii 56.71 3.00e-169 587.00
IUUC-Sja-107772 Schizosaccharomyces japonicus 38.82 2.00e-109 389.00
IUUC-Spo-108202 Schizosaccharomyces pombe 38.78 5.00e-110 390.00
IUUC-Ssl-108535 Sclerotinia sclerotiorum 63.30 1.00e-105 376.00
IUUC-Smo-109309 Selaginella moellendorffii 60.31 1.00e-113 402.00
IUUC-Sit-109745 Setaria italica 43.28 4.00e-118 417.00
IUUC-Sly-110890 Solanum lycopersicum 44.98 2.00e-122 431.00
IUUC-Stu-112144 Solanum tuberosum 57.45 3.00e-110 390.00
IUUC-Sar-113521 Sorex araneus 47.39 6.00e-128 450.00
IUUC-Sbi-114764 Sorghum bicolor 43.05 4.00e-119 420.00
IUUC-Sre-115141 Sporisorium reilianum 66.79 1.00e-113 403.00
IUUC-Ssc-115732 Sus scrofa 55.36 9.00e-165 572.00
IUUC-Tgu-117190 Taeniopygia guttata 55.81 6.00e-168 583.00
IUUC-Tru-118735 Takifugu rubripes 58.95 0.00e+00 672.00
IUUC-Tsy-119503 Tarsius syrichta 56.74 7.00e-174 602.00
IUUC-Tni-119880 Tetraodon nigroviridis 58.91 0.00e+00 672.00
IUUC-Tca-121386 Theobroma cacao 43.78 2.00e-119 421.00
IUUC-Tre-122070 Trichoderma reesei 62.55 8.00e-103 367.00
IUUC-Tvi-122305 Trichoderma virens 61.80 1.00e-101 363.00
IUUC-Tae-123515 Triticum aestivum 43.04 2.00e-116 411.00
IUUC-Tur-126416 Triticum urartu 43.75 1.00e-120 426.00
IUUC-Tme-127174 Tuber melanosporum 42.59 2.00e-68 252.00
IUUC-Tbe-127791 Tupaia belangeri 71.30 5.00e-95 340.00
IUUC-Ttr-129224 Tursiops truncatus 55.25 3.00e-166 577.00
IUUC-Uma-129372 Ustilago maydis 66.79 2.00e-113 402.00
IUUC-Vda-129819 Verticillium dahliae 55.97 3.00e-85 308.00
IUUC-Vpa-130220 Vicugna pacos 58.95 0.00e+00 642.00
IUUC-Vvi-131649 Vitis vinifera 62.11 7.00e-116 409.00
IUUC-Xtr-132954 Xenopus tropicalis 59.36 0.00e+00 681.00
IUUC-Xma-134119 Xiphophorus maculatus 58.52 0.00e+00 667.00
IUUC-Yli-134422 Yarrowia lipolytica 43.70 9.00e-115 406.00
IUUC-Zma-135621 Zea mays 59.08 7.00e-115 407.00
Created Date 25-Jun-2017

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