iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.

Protein Sequence
(Fasta)

MEADGQKYSV LAKTQVREKM MKEIEQISEV FLVSKSDATV ILIRLGWNSF KASDLLGDNK 60
EKFLAKLGLA RVLNSNSSSA DRETGDGDYL VSTPFCSHKF STTCWSEYLS DALKKNKEQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAAGCCG ATGGTCAGAA ATACTCTGTG CTTGCGAAAA CACAAGTCCG TGAGAAGATG 60
ATGAAAGAAA TTGAACAGAT CTCGGAAGTC TTCTTGGTGT CAAAATCGGA TGCAACCGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001876--Znf_RanBP2

PROSITE

PS01358--ZF_RANBP2_1

Pfam

PF01485--IBR

SMART

SM00647--IBR

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

ath:AT5G08730

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006560	Arabidopsis lyrata	84.03	0.00e+00	857.00
IUUC-Bol-016232	Brassica oleracea	55.42	4.00e-145	507.00
IUUC-Bra-016986	Brassica rapa	50.51	4.00e-124	438.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence