iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sly-111237

Ensembl Protein ID

Solyc06g007320.2.1

UniProt Accession

K4C3B5; K4C3B5_SOLLC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Solyc06g007320.2	Solyc06g007320.2.1	Solyc06g007320.2.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.10e-175	584.6	413	901

Active Site

Position(s)	Description	Evidence
594	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnp 86
           YD Qi ++G + q+kl+ akv++vG g+lGcE+lKnL+l+Gv     g++tv+D+d +e+snl+rqFLfr++++g+ K+ vaa+a++ +np
   Q: 413  YDAQISVFGKKFQKKLEDAKVFMVGSGALGCEFLKNLALMGVacteqGKLTVTDDDVIEKSNLSRQFLFRDWNIGQAKSTVAAAAATSINP 503
           ******************************************************************************************* PP
   S: 87   dvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfc 174
           + +vea ++++ +++e+++   F ++++vV++aldn+ ar++v+++cl+ ++pl+esgtlG + +++ +i++lte y +s+dpp+k++P+c
   Q: 504  QLRVEALQNRVGPETENVFddtFWENLSVVINALDNVNARLYVDQRCLYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMC 594
           *****************99************************************************************************ PP
   S: 175  tlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsi 253
           tl ++p +++h+++wa            + +n +l++ ++ ++ + +   ++ ++ ++++ + l  e  e+fe++i++a+ +f++++ n +
   Q: 595  TLHSFPHNIDHCLTWArsefegllektpAEVNAYLSNPNEYTSAQTNAGDAQARDNLERILECLDRESCETFEDCIAWARLKFEEYFANRV 685
           *********************9999999888888888888888888888999999999999999999************************ PP
   S: 254  kqllksfecdivtkskspfwv.........................................................sfcsnaealqvpe 287
           kql+  f+ d vt+s++pfw+                                                          f + ++a+ v +
   Q: 686  KQLIFTFPEDAVTSSGAPFWSapkrfprplqfsstdpshlhfimaasilraetfgipipdwvkhpqklseavhkvmvpCFQPRKDAKIVTD 776
           ***********************************************************99999988888888877774444433333333 PP
   S: 288  kvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiat 371
             + +   +++ ++       + ++   r +  +g  ++ ++fekddd   ++dl++a+an+ra ++ i++ +d+ + k iag+iipaiat
   Q: 777  EKATSLSSSASIDDaavidELISKLECGRKNLPPGFRMKPIQFEKDDDTnfHMDLIAALANMRARNYCIPE-VDKLKAKFIAGRIIPAIAT 866
           2222222222222246744455666667888889*************************************.******************* PP
   S: 372  tnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           t+a+  Gl+++E++Kv++g  k e ++n+f ++a+
   Q: 867  TTAMATGLVCLELYKVLDGshKLEDYRNTFANLAL 901
           ******************999*********99875 PP

Organism

Solanum lycopersicum

Protein Sequence
(Fasta)

MAFDDGNPHD IDEDLHSRQL AVYGRETMRR LFASNVLVSG IQGLGAEIAK NLILAGVKSV 60
TLHDEGEVQL WDLSSNFIFS ESDVGMNRAL ASVQKLQELN NAVVVSSFTT KLTKEKLSDF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTACACATG AAAATTCTTC TCCATTACTT CTCCATCTTT CCGATCAATC ATTTTCACTC 60
ATATCTTCTC GTTCAATCGG TAATTTTCTC TATCTCCGCT TTAAATTTTG CTAAATCACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000367	Aegilops tauschii	79.86	0.00e+00	1601.00
IUUC-Aml-001311	Ailuropoda melanoleuca	46.36	0.00e+00	884.00
IUUC-Aly-005418	Arabidopsis lyrata	80.96	0.00e+00	1726.00
IUUC-Ath-006992	Arabidopsis thaliana	79.69	0.00e+00	1677.00
IUUC-Afl-008455	Aspergillus flavus	46.21	0.00e+00	811.00
IUUC-Ani-009371	Aspergillus nidulans	47.32	0.00e+00	820.00
IUUC-Ang-009737	Aspergillus niger	46.79	0.00e+00	823.00
IUUC-Aor-010007	Aspergillus oryzae	46.21	0.00e+00	811.00
IUUC-Bta-012767	Bos taurus	46.40	0.00e+00	887.00
IUUC-Bdi-014843	Brachypodium distachyon	80.02	0.00e+00	1594.00
IUUC-Csa-023780	Chlorocebus sabaeus	46.37	0.00e+00	885.00
IUUC-Cho-024682	Choloepus hoffmanni	35.33	9.00e-100	357.00
IUUC-Cme-027290	Cyanidioschyzon merolae	39.21	0.00e+00	681.00
IUUC-Eca-033330	Equus caballus	45.79	0.00e+00	875.00
IUUC-Eeu-035323	Erinaceus europaeus	40.84	1.00e-149	523.00
IUUC-Hsa-045982	Homo sapiens	46.08	0.00e+00	866.00
IUUC-Hvu-047418	Hordeum vulgare	79.80	0.00e+00	1622.00
IUUC-Laf-053948	Loxodonta africana	47.17	0.00e+00	869.00
IUUC-Mcc-055843	Macaca mulatta	46.08	0.00e+00	882.00
IUUC-Mtr-058572	Medicago truncatula	84.40	0.00e+00	1718.00
IUUC-Mla-059176	Melampsora laricipopulina	47.23	0.00e+00	872.00
IUUC-Mga-059721	Meleagris gallopavo	39.05	0.00e+00	637.00
IUUC-Mpu-066409	Mustela putorius furo	46.40	0.00e+00	889.00
IUUC-Oba-075120	Oryza barthii	79.19	0.00e+00	1610.00
IUUC-Obr-076557	Oryza brachyantha	79.49	0.00e+00	1617.00
IUUC-Ogl-077887	Oryza glaberrima	79.19	0.00e+00	1613.00
IUUC-Oin-079370	Oryza indica	76.92	0.00e+00	1591.00
IUUC-Ome-081942	Oryza meridionalis	79.68	0.00e+00	1623.00
IUUC-Oni-082365	Oryza nivara	79.59	0.00e+00	1618.00
IUUC-Opu-083977	Oryza punctata	79.39	0.00e+00	1618.00
IUUC-Osa-085949	Oryza sativa	79.19	0.00e+00	1636.00
IUUC-Pan-092114	Papio anubis	46.08	0.00e+00	882.00
IUUC-Psi-093489	Pelodiscus sinensis	38.43	0.00e+00	659.00
IUUC-Pfo-097184	Poecilia formosa	46.01	0.00e+00	862.00
IUUC-Ppe-101298	Prunus persica	82.73	0.00e+00	1702.00
IUUC-Pgr-103336	Puccinia graminis	45.91	0.00e+00	828.00
IUUC-Ptt-103939	Puccinia triticina	46.01	0.00e+00	829.00
IUUC-Smo-108912	Selaginella moellendorffii	73.96	0.00e+00	1520.00
IUUC-Sit-110281	Setaria italica	80.99	0.00e+00	1652.00
IUUC-Stu-112001	Solanum tuberosum	98.43	0.00e+00	1963.00
IUUC-Sbi-114089	Sorghum bicolor	80.20	0.00e+00	1644.00
IUUC-Sre-115148	Sporisorium reilianum	46.35	0.00e+00	829.00
IUUC-Tae-125113	Triticum aestivum	79.92	0.00e+00	1599.00
IUUC-Tur-126189	Triticum urartu	80.30	0.00e+00	1608.00
IUUC-Tme-127055	Tuber melanosporum	44.99	0.00e+00	791.00
IUUC-Tbe-127587	Tupaia belangeri	40.17	2.00e-133	469.00
IUUC-Uma-129387	Ustilago maydis	46.37	0.00e+00	824.00
IUUC-Vvi-130857	Vitis vinifera	84.97	0.00e+00	1759.00
IUUC-Xtr-132947	Xenopus tropicalis	37.43	4.00e-176	611.00
IUUC-Xma-133805	Xiphophorus maculatus	45.82	0.00e+00	840.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence