iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bra-017391

Ensembl Protein ID

Bra039341.1-P

UniProt Accession

M4FE20; M4FE20_BRARP

Protein Name

Defective in cullin neddylation protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bra039341	Bra039341.1	Bra039341.1-P

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	1.90e-79	267.2	53	227

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 14   kdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkdeqkfkdiYrfafnfakdkg 109
            dp++d+i++eg++ +c dl+v+p+di++Lvl+w+++aat+cefsreef+ gl+alg+dsi klqekl +++selkdeqkf diY faf +ak+kg
   Q: 53   NDPYSDMILAEGVSVLCSDLQVEPQDIVTLVLSWHMNAATACEFSREEFVGGLQALGVDSIGKLQEKLAFMRSELKDEQKFYDIYSFAFGWAKEKG 148
           6999******************************************************************************************** PP
   S: 110  qksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWPvliDefveyl 188
           qksl+ldtai +w+Ll+ae+e++l+++w++fL+++++k+iskDtW++lLef+++++++lsnYd+egaWP+liDefveyl
   Q: 149  QKSLALDTAIGMWQLLFAEKEWPLVNHWCDFLQDRHNKAISKDTWAQLLEFARTVNPMLSNYDAEGAWPYLIDEFVEYL 227
           *****************************************************************************97 PP

Organism

Brassica rapa

Functional Description
(View)

Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

Protein Sequence
(Fasta)

MHKLSRTNRD KLQQYVSITG ASEKSALQAL KASDWQIEAA FDVFYSQPQP KSNDPYSDMI 60
LAEGVSVLCS DLQVEPQDIV TLVLSWHMNA ATACEFSREE FVGGLQALGV DSIGKLQEKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTACGAC TCTTCTTGTC TTCACCTTTT GATGAATCTC TTAGTTTTGC GATTCAGTGG 60
TTTATAATCC ATCTTTGTTG ATATGATCCC TCTCCCTTGT GGCAGCATAA GTTGAGTAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cme-027199	Cyanidioschyzon merolae	29.37	5.00e-08	51.20
IUUC-Sar-113248	Sorex araneus	42.86	2.00e-37	147.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence