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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Sce-106257
UUCD1 version UUC-SaC-00104
Ensembl Protein ID YKL018W
UniProt Accession P36104; D6VXR8; SWD2_YEAST
Genbank Protein ID CAA81853.1; AAS56420.1; DAA09138.1
Protein Name COMPASS component SWD2; Complex proteins associated with SET1 protein SWD2; Set1C component SWD2
Genbank Nucleotide ID X74152; AY558094; BK006944
Gene Name SWD2; CPS35; SAF37; YKL018W
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YKL018W YKL018W YKL018W
Annotation
mRNA Expression
GEOFFGED
Protein-protein Interaction
IIDiRefIndexHINTMentha
Post-translational Modifications (PTMs)
dbPAFBioGRID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.40e-12 45.1 111 142
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gH + v++l+    + ++++s+s+D ++++WDl
   Q: 111  GHGALVNDLKMnpvN-DTFLSSSYDESVRLWDL 142
           89999******9644.778*************8 PP
   
Organism Saccharomyces cerevisiae
Functional Description
(View)

Functional Description


     Component of the COMPASS (Set1C) complex which consists of SET1(2), BRE2(2), SPP1(2), SDC1(1), SHG1(1), SWD1(1), SWD2(1), and SWD3(1). Component of the cleavage and polyadenylation factor (CPF) complex, which is composed of PTI1, SYC1, SSU72, GLC7, MPE1, REF2, PFS2, PTA1, YSH1/BRR5, SWD2, CFT2/YDH1, YTH1, CFT1/YHH1, FIP1 and PAP1. Component of the APT complex, which is a subcomplex of CPF, and is composed of PTI1, SYC1, SSU72, GLC7, REF2, PTA1 and SWD2.
 Component of the COMPASS (Set1C) complex which consists of SET1(2), BRE2(2), SPP1(2), SDC1(1), SHG1(1), SWD1(1), SWD2(1), and SWD3(1). Component of the cleavage and polyadenylation factor (CPF) complex, which is composed of PTI1, SYC1, SSU72, GLC7, MPE1, REF2, PFS2, PTA1, YSH1/BRR5, SWD2, CFT2/YDH1, YTH1, CFT1/YHH1, FIP1 and PAP1. Component of the APT complex, which is a subcomplex of CPF, and is composed of PTI1, SYC1, SSU72, GLC7, REF2, PTA1 and SWD2.
Protein Sequence
(Fasta)
MTTVSINKPN LLKFKHVKSF QPQEKDCGPV TSLNFDDNGQ FLLTSSSNDT MQLYSATNCK 60
FLDTIASKKY GCHSAIFTHA QNECIYSSTM KNFDIKYLNL ETNQYLRYFS GHGALVNDLK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sce-106257|E3,WD_repeat|Saccharomyces cerevisiae
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGACCACCG TGTCCATCAA TAAGCCCAAC CTGCTGAAAT TCAAGCATGT TAAAAGCTTT 60
CAACCTCAAG AAAAAGACTG CGGACCCGTA ACCTCATTGA ATTTCGACGA TAATGGCCAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sce-106257|E3,WD_repeat|Saccharomyces cerevisiae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0158--Chromosome
KW-0181--Complete proteome
KW-0507--mRNA processing
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0779--Telomere
KW-0853--WD repeat
Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0000781--C:chromosome, telomeric region
GO:0005847--C:mRNA cleavage and polyadenylation specificity factor complex
GO:0048188--C:Set1C/COMPASS complex
GO:0003682--F:chromatin binding
GO:0051568--P:histone H3-K4 methylation
GO:0080182--P:histone H3-K4 trimethylation
GO:0034729--P:histone H3-K79 methylation
GO:0031124--P:mRNA 3'-end processing
GO:0031126--P:snoRNA 3'-end processing
GO:0000723--P:telomere maintenance
GO:0030847--P:termination of RNA polymerase II transcription, exosome-dependent
GO:0030846--P:termination of RNA polymerase II transcription, poly(A)-coupled
KEGG sce:YKL018W
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000390 Aegilops tauschii 29.08 1.00e-29 121.00
IUUC-Aml-001221 Ailuropoda melanoleuca 33.75 4.00e-43 166.00
IUUC-Atr-002607 Amborella trichopoda 31.15 2.00e-36 144.00
IUUC-Apl-003817 Anas platyrhynchos 34.62 4.00e-43 167.00
IUUC-Aca-005383 Anolis carolinensis 35.20 4.00e-45 172.00
IUUC-Aly-005437 Arabidopsis lyrata 32.13 6.00e-39 152.00
IUUC-Ath-006793 Arabidopsis thaliana 32.46 3.00e-39 153.00
IUUC-Ago-007804 Ashbya gossypii 66.67 4.00e-141 491.00
IUUC-Acl-008217 Aspergillus clavatus 31.66 3.00e-49 186.00
IUUC-Afl-008539 Aspergillus flavus 34.62 2.00e-53 200.00
IUUC-Afu-009105 Aspergillus fumigatus 33.13 1.00e-51 194.00
IUUC-Ani-009474 Aspergillus nidulans 31.85 4.00e-49 186.00
IUUC-Ang-009858 Aspergillus niger 33.14 6.00e-51 192.00
IUUC-Aor-009955 Aspergillus oryzae 34.62 2.00e-53 200.00
IUUC-Ate-010364 Aspergillus terreus 34.03 7.00e-53 199.00
IUUC-Ame-010661 Astyanax mexicanus 34.94 6.00e-44 169.00
IUUC-Bgr-012008 Blumeria graminis 33.80 9.00e-47 178.00
IUUC-Bta-013022 Bos taurus 34.29 2.00e-42 164.00
IUUC-Bci-013966 Botrytis cinerea 34.01 2.00e-50 191.00
IUUC-Bdi-015066 Brachypodium distachyon 30.94 2.00e-36 144.00
IUUC-Bol-016019 Brassica oleracea 32.03 8.00e-38 148.00
IUUC-Bra-017871 Brassica rapa 31.70 1.00e-37 148.00
IUUC-Cel-018276 Caenorhabditis elegans 30.00 9.00e-35 138.00
IUUC-Cja-019309 Callithrix jacchus 33.75 4.00e-43 166.00
IUUC-Cfa-020345 Canis familiaris 33.75 4.00e-43 166.00
IUUC-Cpo-022227 Cavia porcellus 33.13 9.00e-37 145.00
IUUC-Csa-023267 Chlorocebus sabaeus 33.99 1.00e-44 171.00
IUUC-Cho-024409 Choloepus hoffmanni 30.07 2.00e-30 123.00
IUUC-Cin-025628 Ciona intestinalis 35.11 6.00e-47 178.00
IUUC-Csv-026164 Ciona savignyi 33.65 8.00e-46 175.00
IUUC-Cgl-026516 Colletotrichum gloeosporioides 34.27 3.00e-49 186.00
IUUC-Cne-026890 Cryptococcus neoformans 28.53 9.00e-28 115.00
IUUC-Cme-027288 Cyanidioschyzon merolae 29.94 1.00e-36 144.00
IUUC-Dre-028001 Danio rerio 33.75 4.00e-44 169.00
IUUC-Dno-029056 Dasypus novemcinctus 33.75 4.00e-43 166.00
IUUC-Dor-031078 Dipodomys ordii 33.02 8.00e-27 111.00
IUUC-Dse-031152 Dothistroma septosporum 30.53 2.00e-43 167.00
IUUC-Dme-032085 Drosophila melanogaster 35.65 5.00e-47 179.00
IUUC-Ete-033158 Echinops telfairi 34.32 3.00e-42 163.00
IUUC-Eca-033879 Equus caballus 36.29 6.00e-40 156.00
IUUC-Eeu-035229 Erinaceus europaeus 28.85 4.00e-28 116.00
IUUC-Fca-035896 Felis catus 33.75 4.00e-43 166.00
IUUC-Fal-036843 Ficedula albicollis 34.62 4.00e-43 167.00
IUUC-Fox-037858 Fusarium oxysporum 34.47 4.00e-49 186.00
IUUC-Fso-038386 Fusarium solani 32.65 3.00e-44 170.00
IUUC-Gmo-038506 Gadus morhua 33.87 9.00e-43 166.00
IUUC-Ggr-040090 Gaeumannomyces graminis 35.17 9.00e-55 205.00
IUUC-Gga-040192 Gallus gallus 34.06 8.00e-44 168.00
IUUC-Gac-041551 Gasterosteus aculeatus 31.88 2.00e-44 170.00
IUUC-Gma-044074 Glycine max 30.39 5.00e-38 149.00
IUUC-Ggo-045204 Gorilla gorilla 34.29 2.00e-42 165.00
IUUC-Hsa-045866 Homo sapiens 33.75 4.00e-43 166.00
IUUC-Hvu-047731 Hordeum vulgare 34.30 1.00e-33 134.00
IUUC-Itr-048338 Ictidomys tridecemlineatus 33.75 4.00e-43 166.00
IUUC-Kpa-049249 Komagataella pastoris 40.46 2.00e-64 237.00
IUUC-Lch-050431 Latimeria chalumnae 34.29 1.00e-42 165.00
IUUC-Lpe-050830 Leersia perrieri 30.82 7.00e-37 145.00
IUUC-Lma-053026 Leptosphaeria maculans 29.97 6.00e-45 172.00
IUUC-Laf-054265 Loxodonta africana 36.89 1.00e-34 138.00
IUUC-Mcc-055583 Macaca mulatta 33.75 4.00e-43 166.00
IUUC-Meu-056113 Macropus eugenii 28.12 2.00e-26 110.00
IUUC-Mor-057267 Magnaporthe oryzae 37.03 6.00e-49 186.00
IUUC-Mpo-057502 Magnaporthe poae 35.61 7.00e-54 202.00
IUUC-Mtr-058200 Medicago truncatula 30.49 7.00e-37 145.00
IUUC-Mla-058815 Melampsora laricipopulina 35.21 2.00e-55 207.00
IUUC-Mga-059407 Meleagris gallopavo 35.96 2.00e-41 160.00
IUUC-Mvi-060411 Microbotryum violaceum 31.67 4.00e-49 186.00
IUUC-Mmr-061470 Microcebus murinus 33.75 4.00e-43 166.00
IUUC-Mdo-062860 Monodelphis domestica 33.44 1.00e-42 164.00
IUUC-Mmu-063105 Mus musculus 33.75 4.00e-43 166.00
IUUC-Mac-065314 Musa acuminata 31.68 9.00e-37 145.00
IUUC-Mpu-066472 Mustela putorius furo 35.58 9.00e-41 157.00
IUUC-Mlu-067073 Myotis lucifugus 33.95 9.00e-44 168.00
IUUC-Nfi-068284 Neosartorya fischeri 32.84 1.00e-51 195.00
IUUC-Ncr-068702 Neurospora crassa 37.13 6.00e-50 189.00
IUUC-Nle-069451 Nomascus leucogenys 33.75 4.00e-43 166.00
IUUC-Opr-071112 Ochotona princeps 35.58 9.00e-41 157.00
IUUC-Ont-071988 Oreochromis niloticus 34.62 5.00e-44 170.00
IUUC-Oan-072947 Ornithorhynchus anatinus 35.58 2.00e-40 157.00
IUUC-Ocu-074969 Oryctolagus cuniculus 33.75 4.00e-43 166.00
IUUC-Oba-075229 Oryza barthii 29.18 2.00e-29 121.00
IUUC-Obr-076456 Oryza brachyantha 30.92 7.00e-37 145.00
IUUC-Ogl-076973 Oryza glaberrima 31.48 3.00e-37 146.00
IUUC-Ogu-078068 Oryza glumaepatula 28.85 3.00e-29 120.00
IUUC-Oin-079656 Oryza indica 31.15 5.00e-37 145.00
IUUC-Olo-080893 Oryza longistaminata 26.89 4.00e-26 109.00
IUUC-Ome-081559 Oryza meridionalis 35.63 1.00e-22 97.40
IUUC-Oni-082990 Oryza nivara 28.85 4.00e-29 120.00
IUUC-Opu-083374 Oryza punctata 28.52 2.00e-29 120.00
IUUC-Oru-084354 Oryza rufipogon 28.85 4.00e-29 120.00
IUUC-Osa-086296 Oryza sativa 31.15 5.00e-37 145.00
IUUC-Ola-087095 Oryzias latipes 34.06 6.00e-44 169.00
IUUC-Olu-087603 Ostreococcus lucimarinus 30.28 4.00e-30 123.00
IUUC-Oga-088766 Otolemur garnettii 33.75 4.00e-43 166.00
IUUC-Oar-089565 Ovis aries 33.75 1.00e-42 164.00
IUUC-Ptr-091219 Pan troglodytes 33.00 1.00e-43 167.00
IUUC-Pan-091733 Papio anubis 33.75 4.00e-43 166.00
IUUC-Psi-092972 Pelodiscus sinensis 34.50 3.00e-42 164.00
IUUC-Pma-094332 Petromyzon marinus 32.19 3.00e-45 173.00
IUUC-Pno-094960 Phaeosphaeria nodorum 30.24 1.00e-44 171.00
IUUC-Ppa-095292 Physcomitrella patens 33.87 7.00e-43 165.00
IUUC-Pfo-096775 Poecilia formosa 34.62 1.00e-43 169.00
IUUC-Pab-097721 Pongo abelii 34.08 5.00e-43 166.00
IUUC-Pop-099608 Populus trichocarpa 31.49 2.00e-38 150.00
IUUC-Pca-100635 Procavia capensis 35.96 2.00e-38 150.00
IUUC-Ppe-101452 Prunus persica 31.15 3.00e-37 146.00
IUUC-Pva-102798 Pteropus vampyrus 33.67 6.00e-42 162.00
IUUC-Pgr-103395 Puccinia graminis 34.96 2.00e-52 197.00
IUUC-Ptt-103747 Puccinia triticina 34.49 2.00e-51 194.00
IUUC-Pte-104129 Pyrenophora teres 31.19 2.00e-42 166.00
IUUC-Pyt-104773 Pyrenophora triticirepentis 29.74 1.00e-44 171.00
IUUC-Rno-106127 Rattus norvegicus 33.02 2.00e-38 150.00
IUUC-Sha-106491 Sarcophilus harrisii 30.98 3.00e-40 156.00
IUUC-Sja-107724 Schizosaccharomyces japonicus 33.84 9.00e-50 188.00
IUUC-Spo-108206 Schizosaccharomyces pombe 33.51 8.00e-50 188.00
IUUC-Smo-109591 Selaginella moellendorffii 31.27 3.00e-40 156.00
IUUC-Sit-109858 Setaria italica 32.24 4.00e-37 146.00
IUUC-Sly-111267 Solanum lycopersicum 33.22 7.00e-40 155.00
IUUC-Sar-113079 Sorex araneus 35.58 9.00e-41 157.00
IUUC-Sbi-114232 Sorghum bicolor 34.56 2.00e-31 126.00
IUUC-Sre-115157 Sporisorium reilianum 30.84 1.00e-44 171.00
IUUC-Ssc-116386 Sus scrofa 33.75 4.00e-43 166.00
IUUC-Tgu-116465 Taeniopygia guttata 36.54 1.00e-39 155.00
IUUC-Tru-118713 Takifugu rubripes 34.63 3.00e-45 174.00
IUUC-Tsy-119314 Tarsius syrichta 27.34 1.00e-19 87.80
IUUC-Tni-120237 Tetraodon nigroviridis 34.08 2.00e-41 161.00
IUUC-Tca-121853 Theobroma cacao 31.15 6.00e-38 149.00
IUUC-Tre-122205 Trichoderma reesei 34.56 7.00e-54 202.00
IUUC-Tvi-122471 Trichoderma virens 31.12 4.00e-42 163.00
IUUC-Tae-124428 Triticum aestivum 32.35 3.00e-38 150.00
IUUC-Tur-126512 Triticum urartu 31.13 2.00e-29 121.00
IUUC-Tme-126883 Tuber melanosporum 35.81 9.00e-54 201.00
IUUC-Ttr-128307 Tursiops truncatus 35.58 9.00e-41 157.00
IUUC-Uma-129579 Ustilago maydis 35.48 7.00e-52 195.00
IUUC-Vda-129826 Verticillium dahliae 34.57 1.00e-49 187.00
IUUC-Vpa-130091 Vicugna pacos 35.58 9.00e-41 157.00
IUUC-Vvi-131587 Vitis vinifera 32.35 2.00e-37 147.00
IUUC-Xtr-132660 Xenopus tropicalis 33.97 5.00e-42 163.00
IUUC-Xma-133496 Xiphophorus maculatus 34.06 2.00e-44 170.00
IUUC-Yli-134509 Yarrowia lipolytica 35.53 3.00e-56 209.00
IUUC-Zma-135819 Zea mays 31.02 9.00e-37 145.00
Created Date 25-Jun-2017

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