iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bgr-012183

Ensembl Protein ID

CCU75372

UniProt Accession

N1JBS7; N1JBS7_BLUG1

Genbank Protein ID

CCU75372.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

CAUH01001270

Gene Name

BGHDH14_bgh04208

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
BGHDH14_bgh04208	CCU75372	CCU75372

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.20e-50	168.1	302	785
UBD/Alpha-Helix/UBA	1.70e-24	83.7	650	688

Active Site

Position(s)	Description	Evidence
311	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
740	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeel.............w...kskkkavsprellkalkkeaeefs 85
           tGlkNlgN+CY+ S LQcL+++p++++ ++   ++++     +ep ++l ++l+kl   l             +   ++ +k  +p++l++ ++k ++ef 
   Q: 302  TGLKNLGNSCYLASSLQCLFALPQFQKRYFL--PKDTYFV--QEPAQDLETQLRKLGDGLisgryshpsihshTisdSTYQKGLAPSMLKSLVGKNHPEFC 398
           7************************987777..3333332..5688999999999999996666666666555145677788******************* PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke. 185
           +++qqDa Ef+ +l++ + ++                            +k   +  ++ F++ ++++++cl+c++v  r ++   +s+pvp ++ + ++ 
   Q: 399  TMRQQDAFEFIIHLFKLITRSP---------------------------HKAPLEDPVKAFRFIMEQRLQCLNCKKVRYRCDEQDNISIPVPVRKIK-PSl 471
           *****************99988...........................45566667789********************************99975.446 PP
   S: 186  ................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts.. 267
                            l++cL+sft+ee +e    + c++c ++   +k+  +k++PevL+++  Rf     +++++k++  v + +e + l+++ +   
   Q: 472  gstscgkdnadvyepvLLKQCLDSFTSEEIVE----LICSSCGSNNGFSKRSLFKTFPEVLMINARRFVI--LNWVPTKVDVPVVVGDEpFLLDEYKSYgl 566
           99*****************************9....9*******************************65..459**********9999999998887778 PP
   S: 268  .......................................................................................peekqke....... 274
                                                                                                        e       
   Q: 567  qpceelltdveearptftpneeslqqlesmgfsrnrceralhatgnsdvtaamewlfahlddadidlplelencqplrdlgepdsekI-----Ealaamgf 662
           8888888888888888887777776666666666666666666666666666666666666666666666666666666665555550.....05555555 PP
   S: 275  .........................................................kkkYeLiavvvHsG.slssGHYvayvkn.....ekgkWllfdDs 312
                                                                    + +++L ++++H+G s++sGHYva+v+      +++ W+l++D+
   Q: 663  sqqqarkalretsdsleravewlfshtedtgetefsqpgtesgtnaienlearcddlPAQFQLQSIICHKGaSTHSGHYVAFVRRqipesQSHAWVLYNDE 763
           555555566666666667777777777777777778888888888888999999999****************************776544555******* PP
   S: 313  kVtevkeeevleetgstaYvlfYkr 337
           kV +   +e  +   + aYv++++r
   Q: 764  KVVQALDAEEMK---RFAYVYLFQR 785
           *98775544445...58***99998 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraannnleaAveyLldg 41
           d++k+e l +MGF++++a++aLr+++ +le+Ave+L+++
   Q: 650  DSEKIEALAAMGFSQQQARKALRETSDSLERAVEWLFSH 688
           789**********************************97 PP

Organism

Blumeria graminis

Protein Sequence
(Fasta)

MACKHVDEFE LRPPGPSQAV YKEDCTQCFD SADDPSGLDV CLHCFNGGCT GEKNHSKLHS 60
ISLNHPLALN VRRSRRNLQR DEPPQKISKI AIAAETEADR YEYKTFVRCF TCNLENVDKT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCATGCA AGCACGTTGA TGAGTTTGGT ATGCCTGTTA GCTTCGTTAA AATTCGAATA 60
CAAATCTAAC GTGAACTGCT AGAGTTACGT CCTCCGGGTC CGAGTCAAGC TGTATATAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	31.13	6.00e-91	326.00
IUUC-Aml-002104	Ailuropoda melanoleuca	33.18	1.00e-125	442.00
IUUC-Atr-002580	Amborella trichopoda	31.88	1.00e-104	372.00
IUUC-Apl-003774	Anas platyrhynchos	34.25	8.00e-124	436.00
IUUC-Aca-005368	Anolis carolinensis	34.81	6.00e-131	459.00
IUUC-Aly-005727	Arabidopsis lyrata	32.23	1.00e-111	395.00
IUUC-Ath-006974	Arabidopsis thaliana	32.35	8.00e-112	395.00
IUUC-Ago-007890	Ashbya gossypii	30.93	2.00e-100	357.00
IUUC-Acl-008057	Aspergillus clavatus	52.89	0.00e+00	846.00
IUUC-Afl-008547	Aspergillus flavus	54.30	0.00e+00	739.00
IUUC-Afu-008805	Aspergillus fumigatus	49.66	0.00e+00	748.00
IUUC-Ani-009441	Aspergillus nidulans	50.63	0.00e+00	695.00
IUUC-Ang-009720	Aspergillus niger	56.40	0.00e+00	905.00
IUUC-Aor-010111	Aspergillus oryzae	54.50	0.00e+00	898.00
IUUC-Ate-010531	Aspergillus terreus	49.69	0.00e+00	778.00
IUUC-Ame-011893	Astyanax mexicanus	32.85	1.00e-103	369.00
IUUC-Bta-013179	Bos taurus	33.26	4.00e-125	440.00
IUUC-Bci-013858	Botrytis cinerea	69.49	0.00e+00	1154.00
IUUC-Bdi-014904	Brachypodium distachyon	32.40	5.00e-99	353.00
IUUC-Bol-015296	Brassica oleracea	32.51	4.00e-112	397.00
IUUC-Bra-017939	Brassica rapa	32.18	5.00e-111	393.00
IUUC-Cel-018625	Caenorhabditis elegans	28.06	5.00e-75	273.00
IUUC-Cja-019063	Callithrix jacchus	32.44	3.00e-121	427.00
IUUC-Cfa-020976	Canis familiaris	34.05	9.00e-129	452.00
IUUC-Cpo-022265	Cavia porcellus	33.85	5.00e-128	449.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	31.95	4.00e-63	234.00
IUUC-Csa-024177	Chlorocebus sabaeus	34.60	3.00e-115	407.00
IUUC-Cho-024702	Choloepus hoffmanni	31.59	5.00e-76	277.00
IUUC-Cin-025411	Ciona intestinalis	31.16	3.00e-101	360.00
IUUC-Csv-026347	Ciona savignyi	30.05	1.00e-98	352.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	61.41	0.00e+00	943.00
IUUC-Cne-026831	Cryptococcus neoformans	42.93	2.00e-177	613.00
IUUC-Cme-027335	Cyanidioschyzon merolae	28.19	3.00e-80	291.00
IUUC-Dre-027982	Danio rerio	30.72	6.00e-101	360.00
IUUC-Dno-029034	Dasypus novemcinctus	33.26	1.00e-126	445.00
IUUC-Dor-030479	Dipodomys ordii	34.81	9.00e-59	219.00
IUUC-Dse-031467	Dothistroma septosporum	53.04	0.00e+00	842.00
IUUC-Dme-032075	Drosophila melanogaster	32.20	5.00e-108	383.00
IUUC-Ete-032865	Echinops telfairi	30.36	1.00e-105	375.00
IUUC-Eca-034059	Equus caballus	32.91	1.00e-123	435.00
IUUC-Eeu-035304	Erinaceus europaeus	33.97	3.00e-116	410.00
IUUC-Fca-035515	Felis catus	33.02	7.00e-125	439.00
IUUC-Fal-037271	Ficedula albicollis	35.09	4.00e-122	430.00
IUUC-Fox-037745	Fusarium oxysporum	61.34	0.00e+00	987.00
IUUC-Fso-038158	Fusarium solani	61.09	0.00e+00	974.00
IUUC-Gmo-039071	Gadus morhua	31.89	1.00e-107	382.00
IUUC-Ggr-040098	Gaeumannomyces graminis	60.42	0.00e+00	931.00
IUUC-Gga-040635	Gallus gallus	33.95	2.00e-127	447.00
IUUC-Gac-042528	Gasterosteus aculeatus	32.06	2.00e-107	381.00
IUUC-Gma-043614	Glycine max	31.50	2.00e-103	368.00
IUUC-Ggo-044602	Gorilla gorilla	32.87	2.00e-124	437.00
IUUC-Hsa-045959	Homo sapiens	32.87	2.00e-124	437.00
IUUC-Hvu-047563	Hordeum vulgare	34.99	6.00e-96	342.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	32.98	2.00e-125	441.00
IUUC-Kpa-049156	Komagataella pastoris	39.02	6.00e-162	562.00
IUUC-Lch-049648	Latimeria chalumnae	34.37	3.00e-122	431.00
IUUC-Lpe-051523	Leersia perrieri	31.48	1.00e-97	349.00
IUUC-Loc-052072	Lepisosteus oculatus	30.37	4.00e-108	384.00
IUUC-Lma-053216	Leptosphaeria maculans	57.77	0.00e+00	932.00
IUUC-Laf-054327	Loxodonta africana	32.91	4.00e-125	440.00
IUUC-Mcc-055443	Macaca mulatta	32.79	4.00e-124	437.00
IUUC-Meu-056298	Macropus eugenii	33.39	1.00e-83	302.00
IUUC-Mor-057106	Magnaporthe oryzae	61.38	0.00e+00	987.00
IUUC-Mpo-057589	Magnaporthe poae	60.67	0.00e+00	942.00
IUUC-Mtr-058680	Medicago truncatula	32.40	1.00e-107	382.00
IUUC-Mla-058903	Melampsora laricipopulina	41.06	8.00e-173	598.00
IUUC-Mga-059669	Meleagris gallopavo	33.93	2.00e-120	425.00
IUUC-Mvi-060476	Microbotryum violaceum	44.09	2.00e-177	614.00
IUUC-Mmr-060575	Microcebus murinus	32.79	6.00e-125	439.00
IUUC-Mdo-062183	Monodelphis domestica	32.98	4.00e-125	440.00
IUUC-Mmu-063592	Mus musculus	33.14	1.00e-125	442.00
IUUC-Mac-065634	Musa acuminata	29.18	1.00e-94	338.00
IUUC-Mpu-066082	Mustela putorius furo	34.13	2.00e-128	451.00
IUUC-Mlu-067345	Myotis lucifugus	33.14	3.00e-124	437.00
IUUC-Nfi-068558	Neosartorya fischeri	52.30	0.00e+00	812.00
IUUC-Ncr-068960	Neurospora crassa	59.85	0.00e+00	932.00
IUUC-Nle-070173	Nomascus leucogenys	33.77	3.00e-127	447.00
IUUC-Opr-070556	Ochotona princeps	33.49	3.00e-125	441.00
IUUC-Ont-071502	Oreochromis niloticus	32.73	2.00e-109	387.00
IUUC-Oan-072959	Ornithorhynchus anatinus	40.95	3.00e-46	176.00
IUUC-Ocu-074861	Oryctolagus cuniculus	34.37	2.00e-127	448.00
IUUC-Oba-075109	Oryza barthii	31.15	3.00e-102	364.00
IUUC-Obr-076292	Oryza brachyantha	31.34	1.00e-95	342.00
IUUC-Ogl-077065	Oryza glaberrima	31.82	4.00e-106	377.00
IUUC-Ogu-078776	Oryza glumaepatula	31.15	7.00e-103	366.00
IUUC-Oin-080048	Oryza indica	31.57	4.00e-103	367.00
IUUC-Olo-080711	Oryza longistaminata	30.87	4.00e-92	330.00
IUUC-Ome-081506	Oryza meridionalis	31.43	4.00e-94	337.00
IUUC-Oni-082320	Oryza nivara	30.69	8.00e-100	356.00
IUUC-Opu-083801	Oryza punctata	31.03	5.00e-95	340.00
IUUC-Oru-085139	Oryza rufipogon	30.69	2.00e-100	358.00
IUUC-Osa-085713	Oryza sativa	31.82	5.00e-107	380.00
IUUC-Ola-086951	Oryzias latipes	31.26	3.00e-101	360.00
IUUC-Olu-087822	Ostreococcus lucimarinus	30.88	5.00e-91	327.00
IUUC-Oga-088625	Otolemur garnettii	32.56	1.00e-123	435.00
IUUC-Oar-089995	Ovis aries	33.29	2.00e-125	441.00
IUUC-Ptr-090640	Pan troglodytes	33.57	6.00e-128	449.00
IUUC-Pan-091974	Papio anubis	32.91	2.00e-124	438.00
IUUC-Psi-093957	Pelodiscus sinensis	34.15	1.00e-128	451.00
IUUC-Pma-094242	Petromyzon marinus	38.26	1.00e-69	254.00
IUUC-Pno-094835	Phaeosphaeria nodorum	58.70	0.00e+00	845.00
IUUC-Ppa-095901	Physcomitrella patens	32.21	8.00e-114	402.00
IUUC-Pfo-097148	Poecilia formosa	32.61	1.00e-110	392.00
IUUC-Pab-098068	Pongo abelii	30.89	6.00e-106	376.00
IUUC-Pop-098943	Populus trichocarpa	31.00	3.00e-103	367.00
IUUC-Pca-100738	Procavia capensis	34.36	9.00e-95	339.00
IUUC-Ppe-101315	Prunus persica	30.80	2.00e-98	351.00
IUUC-Pva-102154	Pteropus vampyrus	33.18	1.00e-124	438.00
IUUC-Pgr-103343	Puccinia graminis	42.99	9.00e-148	515.00
IUUC-Ptt-103928	Puccinia triticina	38.44	1.00e-144	505.00
IUUC-Pte-104306	Pyrenophora teres	59.05	0.00e+00	892.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	58.88	0.00e+00	917.00
IUUC-Rno-105801	Rattus norvegicus	33.22	6.00e-126	443.00
IUUC-Sce-106304	Saccharomyces cerevisiae	32.56	7.00e-108	383.00
IUUC-Sha-107635	Sarcophilus harrisii	33.33	1.00e-126	445.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	39.97	1.00e-161	561.00
IUUC-Spo-108144	Schizosaccharomyces pombe	40.65	3.00e-170	590.00
IUUC-Smo-108703	Selaginella moellendorffii	34.07	1.00e-108	385.00
IUUC-Sit-110728	Setaria italica	31.71	1.00e-104	372.00
IUUC-Sly-111523	Solanum lycopersicum	32.61	2.00e-112	398.00
IUUC-Sar-113733	Sorex araneus	37.50	2.00e-58	219.00
IUUC-Sbi-114419	Sorghum bicolor	32.28	5.00e-103	367.00
IUUC-Sre-115225	Sporisorium reilianum	42.56	1.00e-171	595.00
IUUC-Ssc-115686	Sus scrofa	32.87	1.00e-124	438.00
IUUC-Tgu-117346	Taeniopygia guttata	34.18	2.00e-124	437.00
IUUC-Tru-118350	Takifugu rubripes	31.05	2.00e-106	377.00
IUUC-Tsy-119278	Tarsius syrichta	31.96	4.00e-89	320.00
IUUC-Tni-120658	Tetraodon nigroviridis	30.99	2.00e-101	361.00
IUUC-Tca-121585	Theobroma cacao	31.72	4.00e-104	370.00
IUUC-Tre-122043	Trichoderma reesei	61.68	0.00e+00	940.00
IUUC-Tvi-122303	Trichoderma virens	61.09	0.00e+00	964.00
IUUC-Tae-123798	Triticum aestivum	32.11	9.00e-106	375.00
IUUC-Tur-126732	Triticum urartu	30.87	3.00e-97	347.00
IUUC-Tme-126909	Tuber melanosporum	57.20	0.00e+00	874.00
IUUC-Tbe-127261	Tupaia belangeri	30.07	6.00e-74	270.00
IUUC-Ttr-128295	Tursiops truncatus	27.54	4.00e-81	294.00
IUUC-Uma-129599	Ustilago maydis	43.15	0.00e+00	640.00
IUUC-Vda-129688	Verticillium dahliae	60.23	0.00e+00	932.00
IUUC-Vpa-130170	Vicugna pacos	36.16	1.00e-44	172.00
IUUC-Vvi-131116	Vitis vinifera	31.60	6.00e-102	363.00
IUUC-Xtr-131953	Xenopus tropicalis	33.41	5.00e-116	410.00
IUUC-Xma-133837	Xiphophorus maculatus	32.49	4.00e-110	390.00
IUUC-Yli-134510	Yarrowia lipolytica	43.30	1.00e-163	568.00
IUUC-Zma-135786	Zea mays	31.55	6.00e-96	343.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence