iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pop-098855

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

CM000337

Gene Name

POPTRDRAFT_582070; POPTR_0001s41930g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
POPTR_0001s41930	POPTR_0001s41930.1	POPTR_0001s41930.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.40e-54	184.3	309	804
UBD/Alpha-Helix/UBA	6.70e-15	55.8	620	659

Active Site

Position(s)	Description	Evidence
318	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
767	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkekln.eenpkepkgellkslqklfeel.....................wkskkkavs 69
           tGl NlgN+CYm +++Q+ ++++++ + +  +++ k++ e +p +p+ +l ++l+kl + +                     +++k++ + 
   Q: 309  TGLVNLGNSCYMAATMQVVFSTRSFNSRFYINQSLKMAfEMAPADPTVDLNMQLTKLAHGMlsgkysvpalenddkanavtsTSNKQEGIP 399
           7************************99988855555541456789999*************999999999999999988765599999*** PP
   S: 70   prellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecd 160
           pr++++++++ ++efs+++qqDa Ef+ ++ldq+e+                               k     s+ F++ ++++i c++ +
   Q: 400  PRMFKAVIAASHPEFSSMRQQDALEFFLHFLDQVERVN---------------------------GGKPALDPSRSFKFGIEERISCPSGK 463
           **********************************9977...........................44555567899***********9877 PP
   S: 161  nvs.sreepfldlslpvpgkeetkke.............................slqdcLesftkeeelegenkyycekckkkqeaekkl 221
                r    + lsl++p +e t+ke                              l+ cL++f+++ee+++   yy++  k+k++a k+ 
   Q: 464  VGFnRR--LDYILSLNIPLHEATNKEeleafgklkaektsegkdlssdeivrprvPLEACLANFSAPEEIQD---YYSTALKAKTTALKTA 549
           666344..445666666666655566679*****************************************97...**************** PP
   S: 222  klkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts............................................. 267
           +l+++P++L+lh+ +f + ee+++++k++ ++++p+ +d+s + ++                                             
   Q: 550  GLTSFPDYLVLHMRKF-VLEEGWVPKKLDVYIDVPDIIDISYMRSKglqpgeellpddvpeaevesnmplanedivsqlvsmgfnylhcqk 639
           ****************.67889*******************66666888888888888888888888877777777777777777777777 PP
   S: 268  ...........................................................peekqke......................... 274
                                                                      +                               
   Q: 640  aainssnagveeamnwllshmddpdidapvsqgahgnevvdqlkvdtllsfgfqeeiarK-----Alkasggdiekatdwifnnpdasvss 725
           777776666666666666666666666666666666666655555555555555555550.....05555555555555555555555566 PP
   S: 275  .....................kkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
                                  kY+L+++v+H+G s+++GHYva++ + +g+W  f+DskV ++   +  +   + +Y++f++r
   Q: 726  dmdtstssskptpddtelpdgGGKYKLFGIVSHMGtSTHCGHYVAHILK-DGRWAIFNDSKVAVS--VNLPK---DMGYLYFFER 804
           6666666677788888888999***************************.9***********998..45666...8999999987 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           +ed++ qlv+MGF+  ++++a  ++ n  +e+A+++Ll++
   Q: 620  NEDIVSQLVSMGFNYLHCQKAAINSsNAGVEEAMNWLLSH 659
           89************************************97 PP

Organism

Populus trichocarpa

Protein Sequence
(Fasta)

MDLLRSNLSR VRIPEPTNRI YKQECCVSFE TPRSEGGLFV DMTTFLAFGK DYVGWNYEKT 60
GNPVYLHIKQ TRKVVPEDRP LKKPTLLAIG VEGGFDNNEP EHEENHNIVI LPDYVTLPFP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATATTTCCAT GTATACATAA AAAAGCCCTC TCTCAATAAA ATCTCTTCAA AAAATAAAAT 60
AAAAAAACGT TTCGAGTCGA TAAACCCTAT GGACCTGCTC CGATCAAATC TCTCACGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

pop:POPTR_0001s41930g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002580	Amborella trichopoda	70.15	0.00e+00	1212.00
IUUC-Aly-005727	Arabidopsis lyrata	78.07	0.00e+00	1283.00
IUUC-Ani-009441	Aspergillus nidulans	38.20	3.00e-98	352.00
IUUC-Ate-010531	Aspergillus terreus	33.01	1.00e-100	360.00
IUUC-Bci-013858	Botrytis cinerea	33.05	8.00e-118	417.00
IUUC-Bol-015296	Brassica oleracea	77.08	0.00e+00	1274.00
IUUC-Bra-017939	Brassica rapa	77.32	0.00e+00	1278.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	39.91	2.00e-112	399.00
IUUC-Cho-024702	Choloepus hoffmanni	41.32	2.00e-115	409.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	32.64	4.00e-103	368.00
IUUC-Cme-027335	Cyanidioschyzon merolae	26.23	1.00e-54	207.00
IUUC-Ggr-040098	Gaeumannomyces graminis	32.72	5.00e-108	384.00
IUUC-Gma-043614	Glycine max	82.13	0.00e+00	1293.00
IUUC-Lma-053216	Leptosphaeria maculans	33.54	9.00e-106	378.00
IUUC-Mor-057106	Magnaporthe oryzae	33.29	1.00e-112	400.00
IUUC-Mpo-057589	Magnaporthe poae	32.40	3.00e-109	389.00
IUUC-Mtr-058680	Medicago truncatula	80.65	0.00e+00	1323.00
IUUC-Mvi-060476	Microbotryum violaceum	32.62	7.00e-103	367.00
IUUC-Mac-065446	Musa acuminata	68.62	0.00e+00	1170.00
IUUC-Pma-094242	Petromyzon marinus	47.69	4.00e-103	367.00
IUUC-Pno-094835	Phaeosphaeria nodorum	35.84	1.00e-101	363.00
IUUC-Pca-100738	Procavia capensis	44.24	7.00e-143	501.00
IUUC-Ppe-101315	Prunus persica	84.16	0.00e+00	1355.00
IUUC-Pgr-103343	Puccinia graminis	32.80	3.00e-97	348.00
IUUC-Ptt-103928	Puccinia triticina	29.05	3.00e-91	328.00
IUUC-Pte-104306	Pyrenophora teres	32.62	9.00e-99	354.00
IUUC-Sly-111523	Solanum lycopersicum	76.33	0.00e+00	1278.00
IUUC-Uma-129599	Ustilago maydis	33.14	2.00e-112	399.00
IUUC-Vvi-131116	Vitis vinifera	83.23	0.00e+00	1301.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence