iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062751

Ensembl Protein ID

ENSMODP00000013059.2

UniProt Accession

F7A6S5; F7A6S5_MONDO

Protein Name

Uncharacterized protein

Gene Name

VPS36

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000010420.2	ENSMODT00000013297.2	ENSMODP00000013059.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/PH/GLUE	4.10e-72	240.8	1	138

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/PH/GLUE

   S: 1    mdrfvytealLeinetlvirqrsvkiydgdekikfdaGellLtthRLiWirdqkneevtlaipLsavvfieeeaaaigksakivvhlhp 89
           mdrfv+t++lLeinetlvi+qr+v+iydg+ekikfdaG llL+thRLiW rdqkn+e+++aipLs++vfiee+aa+igksakiv+hlhp
   Q: 1    MDRFVWTNGLLEINETLVIQQRGVRIYDGEEKIKFDAGVLLLSTHRLIW-RDQKNHECCIAIPLSQIVFIEEQAAGIGKSAKIVIHLHP 88
           9************************************************.*************************************** PP
   S: 90   arsdkePGpldsskasyiklsfkekgdiefyskLseeltaRaWeelevse 139
           a+s+kePGp++ssk+syiklsfke+g+iefy++Lsee+t R+We+++vs+
   Q: 89   ASSNKEPGPFQSSKSSYIKLSFKEHGQIEFYRRLSEEMTHRRWENMPVSQ 138
           ************************************************97 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MDRFVWTNGL LEINETLVIQ QRGVRIYDGE EKIKFDAGVL LLSTHRLIWR DQKNHECCIA 60
IPLSQIVFIE EQAAGIGKSA KIVIHLHPAS SNKEPGPFQS SKSSYIKLSF KEHGQIEFYR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACCGGT TCGTGTGGAC CAACGGCCTC CTGGAGATCA ATGAGACGCT GGTGATCCAG 60
CAGCGTGGGG TCCGCATCTA CGACGGCGAA GAGAAGGTGC GGAGCGGGCA TGCGGGCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR007286--EAP30
IPR021648--GLUE_dom
IPR011993--PH_dom-like
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS51495--GLUE

Pfam

PF04157--EAP30
PF11605--Vps36_ESCRT-II

Gene Ontology

GO:0005829--C:cytosol
GO:0000814--C:ESCRT II complex
GO:0070062--C:extracellular exosome
GO:0031902--C:late endosome membrane
GO:0005764--C:lysosome
GO:0032266--F:phosphatidylinositol-3-phosphate binding
GO:0043130--F:ubiquitin binding
GO:0043328--P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000963	Aegilops tauschii	40.20	1.00e-32	132.00
IUUC-Aml-002313	Ailuropoda melanoleuca	91.12	0.00e+00	710.00
IUUC-Atr-003096	Amborella trichopoda	36.73	2.00e-15	75.90
IUUC-Apl-003218	Anas platyrhynchos	86.67	0.00e+00	675.00
IUUC-Aca-004580	Anolis carolinensis	87.06	0.00e+00	683.00
IUUC-Aly-006398	Arabidopsis lyrata	36.67	6.00e-56	211.00
IUUC-Ath-006907	Arabidopsis thaliana	38.26	4.00e-56	212.00
IUUC-Ago-007840	Ashbya gossypii	20.68	8.00e-03	35.40
IUUC-Acl-008117	Aspergillus clavatus	30.89	2.00e-33	137.00
IUUC-Afl-008595	Aspergillus flavus	30.57	2.00e-35	143.00
IUUC-Afu-008918	Aspergillus fumigatus	31.02	3.00e-33	136.00
IUUC-Ani-009206	Aspergillus nidulans	31.44	7.00e-34	139.00
IUUC-Ang-009784	Aspergillus niger	31.82	4.00e-31	129.00
IUUC-Aor-010126	Aspergillus oryzae	30.57	2.00e-35	143.00
IUUC-Ate-010303	Aspergillus terreus	31.40	6.00e-32	132.00
IUUC-Ame-011190	Astyanax mexicanus	83.33	0.00e+00	652.00
IUUC-Bgr-011979	Blumeria graminis	31.03	1.00e-30	127.00
IUUC-Bta-012661	Bos taurus	91.62	0.00e+00	714.00
IUUC-Bci-013982	Botrytis cinerea	31.00	1.00e-30	127.00
IUUC-Bdi-014753	Brachypodium distachyon	39.12	7.00e-49	187.00
IUUC-Bol-015465	Brassica oleracea	41.90	4.00e-47	182.00
IUUC-Bra-016794	Brassica rapa	42.75	2.00e-48	186.00
IUUC-Cel-018514	Caenorhabditis elegans	40.15	3.00e-77	281.00
IUUC-Cja-019285	Callithrix jacchus	89.50	0.00e+00	631.00
IUUC-Cfa-020746	Canis familiaris	91.62	0.00e+00	709.00
IUUC-Cpo-022005	Cavia porcellus	90.06	0.00e+00	643.00
IUUC-Cre-022686	Chlamydomonas reinhardtii	34.91	1.00e-30	127.00
IUUC-Csa-023520	Chlorocebus sabaeus	91.37	0.00e+00	711.00
IUUC-Cho-024957	Choloepus hoffmanni	87.06	0.00e+00	672.00
IUUC-Cin-025575	Ciona intestinalis	52.63	2.00e-08	50.10
IUUC-Csv-025942	Ciona savignyi	52.54	5.00e-107	380.00
IUUC-Cgl-026558	Colletotrichum gloeosporioides	32.06	2.00e-30	127.00
IUUC-Cne-026915	Cryptococcus neoformans	28.16	5.00e-22	98.60
IUUC-Cme-027099	Cyanidioschyzon merolae	25.10	3.00e-10	60.10
IUUC-Dre-027753	Danio rerio	82.31	0.00e+00	645.00
IUUC-Dno-029922	Dasypus novemcinctus	89.59	0.00e+00	701.00
IUUC-Dor-030643	Dipodomys ordii	83.25	0.00e+00	635.00
IUUC-Dse-031368	Dothistroma septosporum	30.56	4.00e-27	116.00
IUUC-Dme-031977	Drosophila melanogaster	44.23	4.00e-91	328.00
IUUC-Ete-032381	Echinops telfairi	71.75	3.00e-137	481.00
IUUC-Eca-033937	Equus caballus	89.50	0.00e+00	635.00
IUUC-Eeu-034483	Erinaceus europaeus	86.80	0.00e+00	697.00
IUUC-Fca-035496	Felis catus	90.88	0.00e+00	644.00
IUUC-Fal-036743	Ficedula albicollis	87.56	0.00e+00	687.00
IUUC-Fox-037685	Fusarium oxysporum	33.86	2.00e-25	110.00
IUUC-Fso-038421	Fusarium solani	34.76	1.00e-25	111.00
IUUC-Gmo-039456	Gadus morhua	77.49	2.00e-172	598.00
IUUC-Ggr-039763	Gaeumannomyces graminis	31.76	5.00e-34	139.00
IUUC-Gga-040556	Gallus gallus	87.31	0.00e+00	682.00
IUUC-Gac-041481	Gasterosteus aculeatus	79.34	6.00e-158	550.00
IUUC-Gma-044185	Glycine max	43.25	7.00e-51	194.00
IUUC-Ggo-044849	Gorilla gorilla	91.62	0.00e+00	711.00
IUUC-Hsa-046228	Homo sapiens	91.62	0.00e+00	711.00
IUUC-Hvu-047858	Hordeum vulgare	37.27	3.00e-13	68.90
IUUC-Itr-048068	Ictidomys tridecemlineatus	88.38	0.00e+00	682.00
IUUC-Kpa-049240	Komagataella pastoris	25.00	8.00e-06	45.40
IUUC-Lch-050293	Latimeria chalumnae	85.13	8.00e-123	432.00
IUUC-Lpe-051363	Leersia perrieri	43.65	4.00e-49	189.00
IUUC-Loc-052866	Lepisosteus oculatus	82.99	0.00e+00	637.00
IUUC-Lma-053139	Leptosphaeria maculans	31.82	7.00e-32	132.00
IUUC-Laf-053881	Loxodonta africana	85.03	0.00e+00	654.00
IUUC-Mcc-055158	Macaca mulatta	91.12	0.00e+00	710.00
IUUC-Meu-056126	Macropus eugenii	75.41	1.00e-139	489.00
IUUC-Mor-057092	Magnaporthe oryzae	30.29	6.00e-30	125.00
IUUC-Mpo-057629	Magnaporthe poae	33.96	2.00e-26	112.00
IUUC-Mtr-058039	Medicago truncatula	43.82	1.00e-51	197.00
IUUC-Mla-058913	Melampsora laricipopulina	32.69	2.00e-24	107.00
IUUC-Mga-059956	Meleagris gallopavo	87.31	0.00e+00	683.00
IUUC-Mvi-060570	Microbotryum violaceum	24.09	7.00e-18	85.90
IUUC-Mmr-061769	Microcebus murinus	90.33	0.00e+00	642.00
IUUC-Mmu-063115	Mus musculus	89.34	0.00e+00	702.00
IUUC-Mac-064979	Musa acuminata	34.04	5.00e-49	188.00
IUUC-Mpu-066904	Mustela putorius furo	88.16	4.00e-126	443.00
IUUC-Mlu-067474	Myotis lucifugus	90.36	0.00e+00	699.00
IUUC-Nfi-068588	Neosartorya fischeri	30.58	1.00e-30	127.00
IUUC-Ncr-068855	Neurospora crassa	29.48	4.00e-26	112.00
IUUC-Nle-069660	Nomascus leucogenys	90.86	0.00e+00	706.00
IUUC-Opr-070695	Ochotona princeps	90.10	0.00e+00	703.00
IUUC-Ont-071837	Oreochromis niloticus	82.31	1.00e-172	598.00
IUUC-Oan-072903	Ornithorhynchus anatinus	90.33	0.00e+00	647.00
IUUC-Ocu-074833	Oryctolagus cuniculus	89.85	0.00e+00	706.00
IUUC-Oba-075899	Oryza barthii	43.95	3.00e-49	188.00
IUUC-Obr-076125	Oryza brachyantha	40.32	3.00e-53	202.00
IUUC-Ogl-077538	Oryza glaberrima	47.30	5.00e-30	125.00
IUUC-Ogu-078272	Oryza glumaepatula	43.65	3.00e-49	189.00
IUUC-Oin-079158	Oryza indica	42.91	1.00e-48	187.00
IUUC-Olo-080496	Oryza longistaminata	42.74	2.00e-45	175.00
IUUC-Ome-081440	Oryza meridionalis	43.32	5.00e-47	181.00
IUUC-Oni-083069	Oryza nivara	42.91	1.00e-48	187.00
IUUC-Opu-083838	Oryza punctata	44.03	1.00e-47	183.00
IUUC-Oru-084377	Oryza rufipogon	43.65	3.00e-49	189.00
IUUC-Osa-085976	Oryza sativa	43.65	3.00e-49	189.00
IUUC-Ola-086431	Oryzias latipes	83.33	2.00e-174	604.00
IUUC-Olu-087789	Ostreococcus lucimarinus	37.97	5.00e-37	147.00
IUUC-Oga-089152	Otolemur garnettii	90.10	0.00e+00	702.00
IUUC-Oar-089198	Ovis aries	91.44	0.00e+00	650.00
IUUC-Ptr-091123	Pan troglodytes	91.62	0.00e+00	711.00
IUUC-Pan-092866	Papio anubis	88.10	0.00e+00	682.00
IUUC-Psi-093384	Pelodiscus sinensis	90.61	0.00e+00	703.00
IUUC-Pno-094773	Phaeosphaeria nodorum	36.69	5.00e-15	75.90
IUUC-Ppa-095753	Physcomitrella patens	35.40	4.00e-53	202.00
IUUC-Pfo-096028	Poecilia formosa	81.28	4.00e-172	597.00
IUUC-Pop-098915	Populus trichocarpa	43.82	3.00e-50	192.00
IUUC-Pca-100422	Procavia capensis	88.40	0.00e+00	627.00
IUUC-Ppe-101564	Prunus persica	43.87	7.00e-52	197.00
IUUC-Pva-103019	Pteropus vampyrus	85.53	0.00e+00	656.00
IUUC-Pgr-103670	Puccinia graminis	29.60	8.00e-21	95.50
IUUC-Ptt-103958	Puccinia triticina	27.31	3.00e-19	89.70
IUUC-Pte-104343	Pyrenophora teres	30.64	4.00e-35	142.00
IUUC-Pyt-104554	Pyrenophora triticirepentis	30.60	2.00e-36	147.00
IUUC-Rno-105775	Rattus norvegicus	89.09	0.00e+00	701.00
IUUC-Sha-106468	Sarcophilus harrisii	96.13	0.00e+00	682.00
IUUC-Sja-107850	Schizosaccharomyces japonicus	23.80	2.00e-16	80.10
IUUC-Spo-108225	Schizosaccharomyces pombe	22.52	2.00e-16	80.50
IUUC-Ssl-108412	Sclerotinia sclerotiorum	31.86	9.00e-29	121.00
IUUC-Smo-108898	Selaginella moellendorffii	34.84	2.00e-53	202.00
IUUC-Sit-110126	Setaria italica	33.16	7.00e-47	181.00
IUUC-Sly-110884	Solanum lycopersicum	36.88	6.00e-54	204.00
IUUC-Stu-112573	Solanum tuberosum	36.58	5.00e-52	198.00
IUUC-Sar-113114	Sorex araneus	88.06	7.00e-67	247.00
IUUC-Sbi-114331	Sorghum bicolor	29.22	3.00e-35	142.00
IUUC-Sre-115135	Sporisorium reilianum	22.34	8.00e-10	58.90
IUUC-Ssc-116158	Sus scrofa	92.13	0.00e+00	717.00
IUUC-Tgu-116962	Taeniopygia guttata	87.56	0.00e+00	659.00
IUUC-Tru-117567	Takifugu rubripes	81.54	3.00e-173	600.00
IUUC-Tsy-119357	Tarsius syrichta	74.37	1.00e-150	525.00
IUUC-Tni-120047	Tetraodon nigroviridis	80.50	2.00e-152	531.00
IUUC-Tca-121097	Theobroma cacao	43.82	1.00e-51	197.00
IUUC-Tre-122075	Trichoderma reesei	32.58	7.00e-31	129.00
IUUC-Tvi-122623	Trichoderma virens	32.15	3.00e-37	150.00
IUUC-Tae-123728	Triticum aestivum	42.06	1.00e-48	187.00
IUUC-Tur-125988	Triticum urartu	40.69	4.00e-38	151.00
IUUC-Tme-126936	Tuber melanosporum	30.41	1.00e-32	134.00
IUUC-Tbe-127481	Tupaia belangeri	62.98	1.00e-119	422.00
IUUC-Ttr-128160	Tursiops truncatus	90.61	0.00e+00	697.00
IUUC-Uma-129428	Ustilago maydis	26.06	6.00e-17	82.80
IUUC-Vda-129877	Verticillium dahliae	31.83	1.00e-28	121.00
IUUC-Vpa-130358	Vicugna pacos	91.44	0.00e+00	647.00
IUUC-Vvi-131406	Vitis vinifera	36.46	4.00e-55	209.00
IUUC-Xtr-132548	Xenopus tropicalis	82.03	0.00e+00	635.00
IUUC-Xma-133352	Xiphophorus maculatus	81.54	5.00e-172	597.00
IUUC-Yli-134466	Yarrowia lipolytica	30.70	1.00e-18	87.80
IUUC-Zma-135081	Zea mays	39.04	7.00e-48	184.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence