iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026986

Ensembl Protein ID

AAW41993

UniProt Accession

Q5KLE4; Q5KLE4_CRYNJ

Genbank Protein ID

AAW41993.1

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

AE017342

Gene Name

CNB05570

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNB05570	AAW41993	AAW41993

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-36	121.8	98	130
UBD/Beta-Prp	2.60e-71	238.6	13	299

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrt 32
           H d ++cl   ++  l+++GsdD tik+WD+++
   Q: 98   HPDYIRCLTVhPTlSLVLTGSDDMTIKCWDWDK 130
           99******99998899**************976 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdk 108
           ++++++++v+f+p +++++ g ++g +k+wd++tg+ ++ ++  + +v++v+++ +++++v+gs+D  ++v+++stg+ +  +++h d++++l+++p+ + 
   Q: 13   ARSDRVKSVDFHPTEPHVICGLYNGQVKIWDYETGTDVKAFEVTDVPVRCVRYIARKNWFVSGSDDFQLRVYNISTGEKITQFEAHPDYIRCLTVHPTLSL 113
           568999*********************************************************************************************** PP
   S: 109  lvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng..kelvsgsldgtvkl 206
           +++Gs+d ti++wd+++g+   ++++gh++ ++ ++++p++ + ++s++lD tv++W+l +      l+  h++ v+ +++ + g  +++v+ ++d+ vk+
   Q: 114  VLTGSDDMTIKCWDWDKGWRCVQIFEGHTHYIMALAINPKDpQTFASACLDHTVKVWSLGNSVPNFSLEA-HEKGVNYVDYYHGGdkPYIVTTGDDRLVKI 213
           *******************8888**********************************9977777777776.*********9988888************** PP
   S: 207  wdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwkl 294
           wd+++++cv+tl+ ht+nv+   f+p   ++vsgs+Dg+++iW + +  l +tl++  ++ ++va+ + ++n+++ g +d  + + kl
   Q: 214  WDYHSKSCVQTLESHTANVSFAIFHPSLPIIVSGSEDGTVKIWHSATYRLENTLSYGLERAWCVAY-KKSGNEVAVG-FDEGAVVVKL 299
           ******************************************************************.7777776665.5555555566 PP

Organism

Cryptococcus neoformans

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MPMLLDITRK LLARSDRVKS VDFHPTEPHV ICGLYNGQVK IWDYETGTDV KAFEVTDVPV 60
RCVRYIARKN WFVSGSDDFQ LRVYNISTGE KITQFEAHPD YIRCLTVHPT LSLVLTGSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCCGACCA TACTCCGTAC ATCCCCGTTT ATCCCCCTTC CGTCCTTCCT CCTACCTGCA 60
CCTGCCTGAG TAACCATGGT GAGTGACAAT CCCAGCTAAC AACGCCCCCT TGCTCTCGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011044--Quino_amine_DH_bsu
IPR023294--Tachylectin2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0005829--C:cytosol
GO:0000139--C:Golgi membrane
GO:0005634--C:nucleus
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0032511--P:late endosome to vacuole transport via multivesicular body sorting pathway
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

cne:CNB05570

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	42.40	0.00e+00	716.00
IUUC-Aml-002154	Ailuropoda melanoleuca	51.63	0.00e+00	915.00
IUUC-Atr-003090	Amborella trichopoda	48.34	0.00e+00	842.00
IUUC-Apl-003976	Anas platyrhynchos	51.51	0.00e+00	916.00
IUUC-Aca-004301	Anolis carolinensis	51.81	0.00e+00	922.00
IUUC-Aly-006508	Arabidopsis lyrata	48.97	0.00e+00	854.00
IUUC-Ath-007635	Arabidopsis thaliana	48.91	0.00e+00	853.00
IUUC-Ago-007914	Ashbya gossypii	47.98	0.00e+00	784.00
IUUC-Acl-008237	Aspergillus clavatus	56.99	0.00e+00	965.00
IUUC-Afl-008535	Aspergillus flavus	57.25	0.00e+00	937.00
IUUC-Afu-008845	Aspergillus fumigatus	57.18	0.00e+00	945.00
IUUC-Ani-009135	Aspergillus nidulans	57.26	0.00e+00	932.00
IUUC-Ang-009654	Aspergillus niger	58.92	0.00e+00	874.00
IUUC-Aor-009939	Aspergillus oryzae	57.28	0.00e+00	983.00
IUUC-Ate-010355	Aspergillus terreus	56.74	0.00e+00	932.00
IUUC-Ame-010922	Astyanax mexicanus	46.14	0.00e+00	778.00
IUUC-Bgr-012249	Blumeria graminis	57.14	0.00e+00	946.00
IUUC-Bta-013579	Bos taurus	51.36	0.00e+00	831.00
IUUC-Bci-013866	Botrytis cinerea	58.82	0.00e+00	951.00
IUUC-Bdi-015046	Brachypodium distachyon	48.61	0.00e+00	846.00
IUUC-Bol-016271	Brassica oleracea	49.88	0.00e+00	871.00
IUUC-Bra-017758	Brassica rapa	49.58	0.00e+00	865.00
IUUC-Cel-018387	Caenorhabditis elegans	49.76	0.00e+00	855.00
IUUC-Cja-019145	Callithrix jacchus	51.81	0.00e+00	919.00
IUUC-Cfa-020564	Canis familiaris	51.69	0.00e+00	918.00
IUUC-Cpo-022201	Cavia porcellus	51.63	0.00e+00	915.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	53.82	0.00e+00	848.00
IUUC-Csa-023383	Chlorocebus sabaeus	56.22	0.00e+00	727.00
IUUC-Cho-024454	Choloepus hoffmanni	49.21	0.00e+00	796.00
IUUC-Cin-025681	Ciona intestinalis	49.52	0.00e+00	840.00
IUUC-Csv-026012	Ciona savignyi	49.88	0.00e+00	825.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	53.36	0.00e+00	832.00
IUUC-Cme-027219	Cyanidioschyzon merolae	44.99	0.00e+00	776.00
IUUC-Dre-027846	Danio rerio	50.97	0.00e+00	913.00
IUUC-Dor-030462	Dipodomys ordii	50.97	0.00e+00	747.00
IUUC-Dse-031268	Dothistroma septosporum	57.76	0.00e+00	961.00
IUUC-Dme-031791	Drosophila melanogaster	50.42	0.00e+00	877.00
IUUC-Ete-033166	Echinops telfairi	50.00	9.00e-176	608.00
IUUC-Eca-034180	Equus caballus	50.00	0.00e+00	872.00
IUUC-Eeu-035086	Erinaceus europaeus	38.31	3.00e-88	318.00
IUUC-Fca-036265	Felis catus	51.69	0.00e+00	918.00
IUUC-Fal-037202	Ficedula albicollis	50.56	0.00e+00	873.00
IUUC-Fox-037711	Fusarium oxysporum	57.02	0.00e+00	872.00
IUUC-Fso-038268	Fusarium solani	57.11	0.00e+00	882.00
IUUC-Gmo-039046	Gadus morhua	51.33	0.00e+00	913.00
IUUC-Ggr-039863	Gaeumannomyces graminis	58.19	0.00e+00	917.00
IUUC-Gga-041112	Gallus gallus	51.45	0.00e+00	919.00
IUUC-Gac-041733	Gasterosteus aculeatus	50.48	0.00e+00	886.00
IUUC-Gma-044333	Glycine max	50.36	0.00e+00	875.00
IUUC-Ggo-044984	Gorilla gorilla	51.81	0.00e+00	919.00
IUUC-Hsa-046698	Homo sapiens	51.81	0.00e+00	919.00
IUUC-Hvu-047669	Hordeum vulgare	57.06	4.00e-134	468.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	51.63	0.00e+00	915.00
IUUC-Kpa-049265	Komagataella pastoris	51.99	0.00e+00	893.00
IUUC-Lch-050473	Latimeria chalumnae	51.45	0.00e+00	914.00
IUUC-Lpe-051579	Leersia perrieri	50.00	0.00e+00	858.00
IUUC-Loc-052675	Lepisosteus oculatus	51.21	0.00e+00	915.00
IUUC-Lma-053218	Leptosphaeria maculans	56.90	0.00e+00	944.00
IUUC-Laf-053757	Loxodonta africana	51.39	0.00e+00	909.00
IUUC-Mcc-054859	Macaca mulatta	51.81	0.00e+00	919.00
IUUC-Meu-056174	Macropus eugenii	41.74	5.00e-78	283.00
IUUC-Mor-057264	Magnaporthe oryzae	57.67	0.00e+00	893.00
IUUC-Mpo-057538	Magnaporthe poae	57.59	0.00e+00	931.00
IUUC-Mtr-058310	Medicago truncatula	50.00	0.00e+00	873.00
IUUC-Mla-058937	Melampsora laricipopulina	60.87	0.00e+00	1040.00
IUUC-Mga-059875	Meleagris gallopavo	51.20	0.00e+00	912.00
IUUC-Mvi-060240	Microbotryum violaceum	64.45	0.00e+00	1090.00
IUUC-Mmr-061261	Microcebus murinus	51.69	0.00e+00	917.00
IUUC-Mdo-062076	Monodelphis domestica	51.81	0.00e+00	924.00
IUUC-Mmu-063324	Mus musculus	51.81	0.00e+00	921.00
IUUC-Mac-064636	Musa acuminata	50.25	0.00e+00	852.00
IUUC-Mpu-065961	Mustela putorius furo	51.69	0.00e+00	917.00
IUUC-Mlu-067059	Myotis lucifugus	51.09	0.00e+00	906.00
IUUC-Nfi-068277	Neosartorya fischeri	57.07	0.00e+00	940.00
IUUC-Ncr-068659	Neurospora crassa	55.65	0.00e+00	929.00
IUUC-Nle-069034	Nomascus leucogenys	51.81	0.00e+00	919.00
IUUC-Opr-070334	Ochotona princeps	52.64	0.00e+00	859.00
IUUC-Ont-071563	Oreochromis niloticus	50.85	0.00e+00	906.00
IUUC-Oan-073416	Ornithorhynchus anatinus	50.81	0.00e+00	874.00
IUUC-Ocu-074522	Oryctolagus cuniculus	51.45	0.00e+00	913.00
IUUC-Oba-075760	Oryza barthii	47.95	0.00e+00	835.00
IUUC-Obr-076163	Oryza brachyantha	49.88	0.00e+00	849.00
IUUC-Ogl-077450	Oryza glaberrima	48.80	0.00e+00	857.00
IUUC-Ogu-078994	Oryza glumaepatula	47.95	0.00e+00	834.00
IUUC-Oin-079856	Oryza indica	49.76	0.00e+00	840.00
IUUC-Olo-080731	Oryza longistaminata	47.42	0.00e+00	820.00
IUUC-Ome-081554	Oryza meridionalis	46.99	0.00e+00	773.00
IUUC-Oni-082324	Oryza nivara	47.95	0.00e+00	834.00
IUUC-Opu-083400	Oryza punctata	48.05	0.00e+00	822.00
IUUC-Oru-084829	Oryza rufipogon	47.95	0.00e+00	834.00
IUUC-Osa-086026	Oryza sativa	48.92	0.00e+00	859.00
IUUC-Ola-087245	Oryzias latipes	50.54	0.00e+00	904.00
IUUC-Olu-087655	Ostreococcus lucimarinus	49.82	0.00e+00	846.00
IUUC-Oga-088163	Otolemur garnettii	50.12	0.00e+00	869.00
IUUC-Oar-089842	Ovis aries	51.81	0.00e+00	920.00
IUUC-Ptr-090501	Pan troglodytes	51.81	0.00e+00	919.00
IUUC-Pan-092011	Papio anubis	51.81	0.00e+00	919.00
IUUC-Psi-093308	Pelodiscus sinensis	51.69	0.00e+00	917.00
IUUC-Pma-094695	Petromyzon marinus	49.36	0.00e+00	829.00
IUUC-Pno-094785	Phaeosphaeria nodorum	63.25	6.00e-112	396.00
IUUC-Ppa-095911	Physcomitrella patens	51.27	0.00e+00	872.00
IUUC-Pfo-096587	Poecilia formosa	50.72	0.00e+00	909.00
IUUC-Pab-097926	Pongo abelii	50.66	0.00e+00	858.00
IUUC-Pop-099634	Populus trichocarpa	50.12	0.00e+00	871.00
IUUC-Pca-100965	Procavia capensis	50.79	0.00e+00	884.00
IUUC-Ppe-101470	Prunus persica	50.60	0.00e+00	882.00
IUUC-Pva-102451	Pteropus vampyrus	50.82	0.00e+00	748.00
IUUC-Pgr-103453	Puccinia graminis	63.12	0.00e+00	1079.00
IUUC-Ptt-103868	Puccinia triticina	63.00	0.00e+00	1078.00
IUUC-Pte-104274	Pyrenophora teres	58.27	0.00e+00	972.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	58.00	0.00e+00	926.00
IUUC-Rno-105979	Rattus norvegicus	44.91	0.00e+00	710.00
IUUC-Sce-106269	Saccharomyces cerevisiae	47.77	0.00e+00	797.00
IUUC-Sha-106905	Sarcophilus harrisii	51.81	0.00e+00	922.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	49.45	0.00e+00	814.00
IUUC-Spo-108299	Schizosaccharomyces pombe	48.29	0.00e+00	832.00
IUUC-Smo-108828	Selaginella moellendorffii	49.82	0.00e+00	862.00
IUUC-Sit-110239	Setaria italica	48.80	0.00e+00	858.00
IUUC-Sly-111211	Solanum lycopersicum	49.58	0.00e+00	853.00
IUUC-Stu-112906	Solanum tuberosum	49.29	0.00e+00	790.00
IUUC-Sar-113472	Sorex araneus	49.84	0.00e+00	681.00
IUUC-Sbi-114052	Sorghum bicolor	49.58	0.00e+00	867.00
IUUC-Sre-115040	Sporisorium reilianum	63.70	0.00e+00	1080.00
IUUC-Ssc-115593	Sus scrofa	51.57	0.00e+00	917.00
IUUC-Tgu-117239	Taeniopygia guttata	51.51	0.00e+00	918.00
IUUC-Tru-118025	Takifugu rubripes	50.85	0.00e+00	909.00
IUUC-Tsy-118824	Tarsius syrichta	50.47	0.00e+00	694.00
IUUC-Tni-120142	Tetraodon nigroviridis	50.67	0.00e+00	898.00
IUUC-Tca-121613	Theobroma cacao	49.76	0.00e+00	870.00
IUUC-Tre-122072	Trichoderma reesei	56.09	0.00e+00	916.00
IUUC-Tvi-122546	Trichoderma virens	55.85	0.00e+00	917.00
IUUC-Tae-125395	Triticum aestivum	48.67	0.00e+00	852.00
IUUC-Tur-126283	Triticum urartu	43.24	0.00e+00	713.00
IUUC-Tme-127041	Tuber melanosporum	59.45	0.00e+00	979.00
IUUC-Tbe-127770	Tupaia belangeri	53.59	0.00e+00	788.00
IUUC-Ttr-129294	Tursiops truncatus	51.69	0.00e+00	917.00
IUUC-Uma-129351	Ustilago maydis	62.30	0.00e+00	1082.00
IUUC-Vda-129716	Verticillium dahliae	56.75	0.00e+00	936.00
IUUC-Vpa-130037	Vicugna pacos	39.78	5.00e-97	347.00
IUUC-Vvi-131689	Vitis vinifera	49.82	0.00e+00	861.00
IUUC-Xtr-132633	Xenopus tropicalis	51.45	0.00e+00	917.00
IUUC-Xma-133347	Xiphophorus maculatus	50.85	0.00e+00	910.00
IUUC-Yli-134455	Yarrowia lipolytica	51.58	0.00e+00	827.00
IUUC-Zma-135867	Zea mays	49.16	0.00e+00	865.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence