iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026860

Ensembl Protein ID

AAW42213

UniProt Accession

Q5KKN8; Q5KKN8_CRYNJ

Genbank Protein ID

AAW42213.1

Protein Name

Nuclear matrix protein NMP200, putative

Genbank Nucleotide ID

AE017343

Gene Name

CNC02380

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNC02380	AAW42213	AAW42213

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.30e-11	42.0	2	56
E3 adaptor/Cullin RING/DCX/DWD	9.40e-20	68.4	252	287
UBD/Beta-Prp	1.10e-40	138.1	200	339

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 6    flCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnlt 60
           f C+Is+ +++ Pvv++ sG +y+++ Ie++++++g+ +P+ ++ lt++dlv+ ++
   Q: 2    FFCAISGSPPTVPVVSKtSGAVYEKALIERYIEENGT-DPISGEALTKDDLVDVKA 56
           99***************9******************9.*************99876 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sd.tllvsGsdDgtikvWDlr 31
           gHt  vt +af     + +l +s+s D+t++vW  +
   Q: 252  GHTKAVTHVAFreheGEpRLAISASADKTVRVWGED 287
           8************98445889************855 PP

UBD/Beta-Prp

   S: 41   tgkllrsl.sgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sg..dklvsGshdrtirvwdletgqclee.tlsgh 136
           + + + sl   + a++ta+++ +dg++ vtg+ D++++v+dl+++k + tlkgh++ v+ ++f + +g     +s+s+d+t+rvw  + g++    tlsgh
   Q: 200  QINHVPSLhATKPAGITALDLAQDGNTVVTGGADKAVQVFDLEASKVLGTLKGHTKAVTHVAFREhEGepRLAISASADKTVRVWGEDDGKWGARaTLSGH 300
           555566676677899*************************************************9844448889******************9888***** PP
   S: 137  dgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl 175
           +g +n+++vhp+g+++++Gs+D+t  l+dl+t+k +++ 
   Q: 301  KGEINGLAVHPSGSYVAAGSADSTWSLYDLSTAKEVTKY 339
           *******************************99988776 PP

Organism

Cryptococcus neoformans

Protein Sequence
(Fasta)

MFFCAISGSP PTVPVVSKTS GAVYEKALIE RYIEENGTDP ISGEALTKDD LVDVKAKPST 60
IPPRPANQTS IPALLTALQS EYDSIMLESL EIKKAFQSSR QELANALYRE DAATRVIARL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTTTCT GTGCTAGTGA GTTCCCCGCC CGGCGGCCGT GCGCTCACCG CCCCAGTCTC 60
TGGCTCGCCC CCCACCGTCC CCGTCGTCTC CAAGACCTCG GGCGCCGTCT ACGAAAAAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR013915--Pre-mRNA_splic_Prp19
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51698--U_BOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08606--Prp19
PF00400--WD40

SMART

SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0000974--C:Prp19 complex
GO:0071006--C:U2-type catalytic step 1 spliceosome
GO:0004842--F:ubiquitin-protein transferase activity
GO:0000349--P:generation of catalytic spliceosome for first transesterification step

KEGG

cne:CNC02380

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000488	Aegilops tauschii	35.89	7.00e-80	290.00
IUUC-Aml-001230	Ailuropoda melanoleuca	37.96	5.00e-87	313.00
IUUC-Atr-002594	Amborella trichopoda	37.85	1.00e-92	332.00
IUUC-Apl-003686	Anas platyrhynchos	32.35	2.00e-57	214.00
IUUC-Aca-005272	Anolis carolinensis	37.38	9.00e-90	322.00
IUUC-Aly-005586	Arabidopsis lyrata	37.36	3.00e-94	337.00
IUUC-Ath-007693	Arabidopsis thaliana	36.66	7.00e-93	332.00
IUUC-Ago-007879	Ashbya gossypii	38.95	4.00e-31	127.00
IUUC-Acl-008335	Aspergillus clavatus	35.03	7.00e-52	196.00
IUUC-Afl-008527	Aspergillus flavus	35.62	6.00e-60	223.00
IUUC-Afu-008957	Aspergillus fumigatus	34.37	2.00e-62	231.00
IUUC-Ani-009280	Aspergillus nidulans	36.69	1.00e-51	195.00
IUUC-Ang-009746	Aspergillus niger	37.42	2.00e-60	224.00
IUUC-Aor-009905	Aspergillus oryzae	35.42	2.00e-63	234.00
IUUC-Ate-010412	Aspergillus terreus	37.29	3.00e-56	210.00
IUUC-Ame-011561	Astyanax mexicanus	39.50	2.00e-37	147.00
IUUC-Bgr-012283	Blumeria graminis	30.67	3.00e-52	197.00
IUUC-Bta-013242	Bos taurus	38.28	2.00e-90	324.00
IUUC-Bci-013901	Botrytis cinerea	31.96	2.00e-61	227.00
IUUC-Bdi-014896	Brachypodium distachyon	38.29	9.00e-97	345.00
IUUC-Bol-016045	Brassica oleracea	37.09	6.00e-94	335.00
IUUC-Bra-017902	Brassica rapa	36.90	5.00e-93	332.00
IUUC-Cel-018271	Caenorhabditis elegans	36.90	3.00e-90	323.00
IUUC-Cja-019879	Callithrix jacchus	38.16	1.00e-91	328.00
IUUC-Cfa-020175	Canis familiaris	38.28	1.00e-90	324.00
IUUC-Cpo-022379	Cavia porcellus	38.09	7.00e-90	322.00
IUUC-Cre-022993	Chlamydomonas reinhardtii	37.65	6.00e-87	312.00
IUUC-Csa-023500	Chlorocebus sabaeus	38.28	2.00e-90	323.00
IUUC-Cho-025065	Choloepus hoffmanni	41.91	5.00e-36	142.00
IUUC-Cin-025699	Ciona intestinalis	39.95	2.00e-77	280.00
IUUC-Csv-026128	Ciona savignyi	37.43	4.00e-90	323.00
IUUC-Cgl-026507	Colletotrichum gloeosporioides	34.94	1.00e-61	228.00
IUUC-Dre-028187	Danio rerio	37.30	3.00e-88	317.00
IUUC-Dno-029453	Dasypus novemcinctus	38.28	3.00e-90	323.00
IUUC-Dor-030150	Dipodomys ordii	37.70	5.00e-31	126.00
IUUC-Dse-031220	Dothistroma septosporum	34.38	1.00e-64	238.00
IUUC-Dme-031906	Drosophila melanogaster	36.45	5.00e-86	309.00
IUUC-Ete-033035	Echinops telfairi	33.33	2.00e-37	148.00
IUUC-Eca-033478	Equus caballus	38.28	2.00e-90	323.00
IUUC-Eeu-034974	Erinaceus europaeus	35.87	1.00e-54	205.00
IUUC-Fca-036194	Felis catus	38.09	2.00e-89	321.00
IUUC-Fal-037417	Ficedula albicollis	37.77	4.00e-92	329.00
IUUC-Fox-037922	Fusarium oxysporum	35.38	3.00e-61	227.00
IUUC-Fso-038256	Fusarium solani	35.10	2.00e-66	244.00
IUUC-Gmo-038713	Gadus morhua	37.38	8.00e-91	325.00
IUUC-Ggr-039854	Gaeumannomyces graminis	34.53	1.00e-48	185.00
IUUC-Gga-041143	Gallus gallus	37.57	2.00e-91	327.00
IUUC-Gac-042129	Gasterosteus aculeatus	38.09	6.00e-92	329.00
IUUC-Gma-043635	Glycine max	37.79	2.00e-93	333.00
IUUC-Ggo-045262	Gorilla gorilla	38.28	2.00e-90	323.00
IUUC-Hsa-046036	Homo sapiens	38.28	2.00e-90	323.00
IUUC-Hvu-047442	Hordeum vulgare	38.44	1.00e-56	211.00
IUUC-Itr-048169	Ictidomys tridecemlineatus	36.99	6.00e-90	322.00
IUUC-Kpa-049195	Komagataella pastoris	40.00	2.00e-21	94.70
IUUC-Lch-050105	Latimeria chalumnae	38.16	5.00e-92	329.00
IUUC-Lpe-050976	Leersia perrieri	37.26	2.00e-92	331.00
IUUC-Loc-052042	Lepisosteus oculatus	33.40	9.00e-60	222.00
IUUC-Lma-053143	Leptosphaeria maculans	34.85	2.00e-66	245.00
IUUC-Laf-053451	Loxodonta africana	36.36	4.00e-87	313.00
IUUC-Mcc-055786	Macaca mulatta	38.28	2.00e-90	323.00
IUUC-Meu-056161	Macropus eugenii	32.77	9.00e-32	129.00
IUUC-Mor-057215	Magnaporthe oryzae	38.05	5.00e-57	213.00
IUUC-Mpo-057419	Magnaporthe poae	34.31	5.00e-47	180.00
IUUC-Mtr-057756	Medicago truncatula	37.09	3.00e-89	320.00
IUUC-Mla-059085	Melampsora laricipopulina	44.72	4.00e-107	379.00
IUUC-Mga-060158	Meleagris gallopavo	35.57	8.00e-79	285.00
IUUC-Mvi-060441	Microbotryum violaceum	44.53	5.00e-104	369.00
IUUC-Mmr-061085	Microcebus murinus	38.28	2.00e-90	323.00
IUUC-Mdo-061804	Monodelphis domestica	38.28	6.00e-90	322.00
IUUC-Mmu-063608	Mus musculus	36.91	9.00e-87	311.00
IUUC-Mac-064972	Musa acuminata	38.10	3.00e-88	317.00
IUUC-Mpu-065700	Mustela putorius furo	38.28	2.00e-90	324.00
IUUC-Mlu-068223	Myotis lucifugus	36.69	6.00e-88	316.00
IUUC-Nfi-068504	Neosartorya fischeri	34.25	2.00e-61	228.00
IUUC-Ncr-068729	Neurospora crassa	34.16	9.00e-59	219.00
IUUC-Nle-069754	Nomascus leucogenys	38.28	2.00e-90	323.00
IUUC-Opr-070621	Ochotona princeps	37.08	2.00e-83	301.00
IUUC-Ont-071377	Oreochromis niloticus	37.11	4.00e-89	320.00
IUUC-Oan-073498	Ornithorhynchus anatinus	35.80	2.00e-20	91.30
IUUC-Ocu-074182	Oryctolagus cuniculus	36.77	1.00e-86	311.00
IUUC-Oba-075509	Oryza barthii	37.71	7.00e-92	329.00
IUUC-Obr-076480	Oryza brachyantha	37.71	2.00e-93	334.00
IUUC-Ogl-077052	Oryza glaberrima	37.71	8.00e-92	328.00
IUUC-Ogu-078919	Oryza glumaepatula	37.90	3.00e-92	330.00
IUUC-Oin-079357	Oryza indica	36.07	2.00e-82	298.00
IUUC-Olo-080376	Oryza longistaminata	36.11	9.00e-80	288.00
IUUC-Ome-081973	Oryza meridionalis	36.11	3.00e-79	287.00
IUUC-Oni-082849	Oryza nivara	37.52	2.00e-91	328.00
IUUC-Opu-083243	Oryza punctata	37.71	8.00e-92	328.00
IUUC-Oru-084613	Oryza rufipogon	37.33	1.00e-91	328.00
IUUC-Osa-085407	Oryza sativa	37.71	8.00e-92	328.00
IUUC-Ola-086566	Oryzias latipes	37.62	2.00e-91	327.00
IUUC-Olu-087757	Ostreococcus lucimarinus	39.56	8.00e-87	312.00
IUUC-Oga-089010	Otolemur garnettii	37.19	4.00e-87	313.00
IUUC-Oar-089638	Ovis aries	38.28	2.00e-90	324.00
IUUC-Ptr-091141	Pan troglodytes	38.28	2.00e-90	323.00
IUUC-Pan-092662	Papio anubis	38.28	2.00e-90	323.00
IUUC-Psi-093777	Pelodiscus sinensis	35.36	5.00e-64	236.00
IUUC-Pno-095115	Phaeosphaeria nodorum	33.62	9.00e-63	232.00
IUUC-Ppa-095841	Physcomitrella patens	37.17	4.00e-94	336.00
IUUC-Pfo-096390	Poecilia formosa	36.40	6.00e-89	319.00
IUUC-Pab-098250	Pongo abelii	38.32	6.00e-85	306.00
IUUC-Pop-099854	Populus trichocarpa	38.36	1.00e-93	335.00
IUUC-Pca-100553	Procavia capensis	37.57	1.00e-89	321.00
IUUC-Ppe-101383	Prunus persica	38.05	1.00e-88	318.00
IUUC-Pva-102189	Pteropus vampyrus	38.28	2.00e-90	324.00
IUUC-Pgr-103304	Puccinia graminis	42.07	1.00e-100	358.00
IUUC-Ptt-103984	Puccinia triticina	41.68	6.00e-104	369.00
IUUC-Pte-104385	Pyrenophora teres	33.94	4.00e-62	230.00
IUUC-Pyt-104697	Pyrenophora triticirepentis	33.80	3.00e-63	233.00
IUUC-Rno-105581	Rattus norvegicus	38.28	4.00e-90	323.00
IUUC-Sce-106147	Saccharomyces cerevisiae	36.50	3.00e-22	97.80
IUUC-Sha-107071	Sarcophilus harrisii	36.89	9.00e-87	312.00
IUUC-Sja-107697	Schizosaccharomyces japonicus	30.66	5.00e-43	166.00
IUUC-Spo-108315	Schizosaccharomyces pombe	31.40	1.00e-48	185.00
IUUC-Ssl-108628	Sclerotinia sclerotiorum	33.48	5.00e-59	219.00
IUUC-Smo-109648	Selaginella moellendorffii	37.04	9.00e-95	338.00
IUUC-Sit-109873	Setaria italica	38.10	4.00e-93	333.00
IUUC-Sly-111673	Solanum lycopersicum	38.51	6.00e-90	322.00
IUUC-Stu-112125	Solanum tuberosum	38.51	1.00e-89	321.00
IUUC-Sbi-114696	Sorghum bicolor	35.83	1.00e-79	288.00
IUUC-Sre-115134	Sporisorium reilianum	41.67	3.00e-106	377.00
IUUC-Ssc-116260	Sus scrofa	38.28	1.00e-90	325.00
IUUC-Tgu-116533	Taeniopygia guttata	37.77	7.00e-92	328.00
IUUC-Tru-117800	Takifugu rubripes	36.59	6.00e-88	316.00
IUUC-Tsy-118980	Tarsius syrichta	35.19	2.00e-76	277.00
IUUC-Tni-120334	Tetraodon nigroviridis	33.07	7.00e-73	265.00
IUUC-Tca-121807	Theobroma cacao	38.21	4.00e-96	343.00
IUUC-Tre-121920	Trichoderma reesei	36.12	8.00e-65	239.00
IUUC-Tvi-122294	Trichoderma virens	33.72	1.00e-56	212.00
IUUC-Tae-124231	Triticum aestivum	38.33	1.00e-93	335.00
IUUC-Tur-126199	Triticum urartu	34.42	1.00e-85	308.00
IUUC-Tme-127026	Tuber melanosporum	36.40	1.00e-71	261.00
IUUC-Tbe-127582	Tupaia belangeri	35.87	1.00e-54	205.00
IUUC-Ttr-128313	Tursiops truncatus	38.09	7.00e-90	322.00
IUUC-Uma-129626	Ustilago maydis	40.30	7.00e-105	372.00
IUUC-Vda-129699	Verticillium dahliae	32.70	6.00e-58	216.00
IUUC-Vpa-130593	Vicugna pacos	38.12	2.00e-78	284.00
IUUC-Vvi-131668	Vitis vinifera	37.40	1.00e-94	338.00
IUUC-Xtr-132186	Xenopus tropicalis	38.60	6.00e-77	279.00
IUUC-Xma-133212	Xiphophorus maculatus	36.59	5.00e-89	319.00
IUUC-Yli-134607	Yarrowia lipolytica	46.72	3.00e-34	135.00
IUUC-Zma-135662	Zea mays	37.52	3.00e-93	333.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence