iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-124231

Ensembl Protein ID

TRIAE_CS42_4BL_TGACv1_320268_AA1033180.1

UniProt Accession

W5E2E9; W5E2E9_WHEAT

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_4BL_TGACv1_320268_AA1033180	TRIAE_CS42_4BL_TGACv1_320268_AA1033180.1	TRIAE_CS42_4BL_TGACv1_320268_AA1033180.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.50e-26	92.1	262	291
E3 activity/RING/U-box	1.00e-12	50.6	1	64
UBD/Beta-Prp	6.60e-44	152.9	222	430

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWD 29
           H+ ++t+l+f   d ll++Gs D+t++vW 
   Q: 262  HSKKITSLKFvpRDELLITGSADKTVRVWQ 291
           999********877***************5 PP

E3 activity/RING/U-box

   S: 6    flCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawc 69
           ++C+Is+e+++dPv +  sG  ++r+ I++++++ gk cPvt+++l+ +dlv  +t +    + +
   Q: 1    MICAISGEVPEDPVLSTkSGLLFERRLIQRYVEDHGK-CPVTKEELAMDDLVTVKTDKIPKPRPL 64
           58*************999**************99999.**************9998777666555 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvw 79
             i +++++ +k+++atg+ d    ++d  +g++l +l +h++++t++kf p++++l+tgs D+t++vw
   Q: 222  PGILSIDIHHSKDIIATGGIDTNAVLFDRPSGQVLCTLTDHSKKITSLKFVPRDELLITGSADKTVRVW 290
           233345556666666666666666666666666666666666666666666666666666666666666 PP
   S: 80   dls...tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee..tlsghdgvvncv 143
             +   ++ c ht++ h ++v ++++++s+++++++s+d+t   +d++tg+cl +    sg+dg  +++
   Q: 291  QGNedgSYGCRHTMRDHGAEVEAVTVHASQKYFATASRDSTWCFYDISTGSCLTQvgEASGQDG-YTSA 358
           3333345556666666666666666666666666666666666666666666655533333333.3455 PP
   S: 144  vvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgghtdsvyslsfdsngkelvsgsldgtvklwdlq 210
           ++hpdg +l +G+  +++++Wd+k+++ + ++  + gh + v+ +sf++ng +l++++ldg vklwdl+
   Q: 359  AFHPDGLILGTGTSEGVIKIWDVKSQTRVAKFegEVGHVGTVTAMSFSENGYFLATAALDG-VKLWDLR 426
           5666666666666666666666666666666644334666666666666666666666665.5666665 PP
   S: 211  tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdl 256
                                                     +  +
   Q: 427  ------------------------------------------KLRN 430
           ..........................................4433 PP

Organism

Triticum aestivum

Protein Sequence
(Fasta)

MICAISGEVP EDPVLSTKSG LLFERRLIQR YVEDHGKCPV TKEELAMDDL VTVKTDKIPK 60
PRPLQAASVP GLLGMFQNEW DALMLSNFAL EQQLHTARQE LSHALYQHDA ACRVIARLKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGGTACTGA AAAAAAAAAG GTTTCCAGCG TGCGCCTCGA GCAAATCCAC CCCCTCCCTC 60
CACCAAAACC CCCACCTCGT CGGCGCCACC ACCATTGCCG CCGCCGGAGA ACCCGCCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR013915--Pre-mRNA_splic_Prp19
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51698--U_BOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08606--Prp19
PF00400--WD40

SMART

SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cne-026860	Cryptococcus neoformans	38.33	6.00e-93	335.00
IUUC-Kpa-049195	Komagataella pastoris	46.46	3.00e-23	103.00
IUUC-Mvi-060441	Microbotryum violaceum	36.77	8.00e-73	268.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence