iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004940

Ensembl Protein ID

ENSACAP00000016553.2

UniProt Accession

G1KT54; G1KT54_ANOCA

Protein Name

Uncharacterized protein

Gene Name

HGS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000016808.3	ENSACAT00000016879.2	ENSACAP00000016553.2
ENSACAG00000016808.3	ENSACAT00000029711.1	ENSACAP00000022294.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/VHS	4.60e-51	172.2	15	143

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/VHS

   S: 1    atselvtsedwelileicdliqetkegakdalralrkrinnknphvalraLtlLdscvsnCgkkfhvevaskdlleelrellknenepk 89
           ats+l+ ++dwe+il+icd+i++ +++ak+a+ a++k++n+knphval+aL++L+s+v+nCg+++h+eva+k+++eel+ellk+++e +
   Q: 15   ATSQLLLETDWESILQICDMIRQGDTQAKYAVGAIKKKVNDKNPHVALYALEVLESVVKNCGQTVHDEVANKQTMEELKELLKRQVEAN 103
           799************************************************************************************** PP
   S: 90   vieKlkalivsWadelknepalslivaliktlkeeGlefp 129
           v++K+++li++Wa++++nep++++++++++ +k eG++fp
   Q: 104  VRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFP 143
           ***************************************8 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MGRGGGTFER LLDKATSQLL LETDWESILQ ICDMIRQGDT QAKYAVGAIK KKVNDKNPHV 60
ALYALEVLES VVKNCGQTVH DEVANKQTME ELKELLKRQV EANVRNKILY LIQAWAHAFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGCGAG GCGGAGGCAC CTTCGAGCGG CTCCTCGGTA CCTGGAGGCG GGGAGCAGGC 60
TGAGGGTAGC GGCTGCCGGA GGCTCAGCTG CAGCCCGGGA GCGGGGAAGC TCAAATCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008942--ENTH_VHS
IPR024641--HRS_helical
IPR017073--Ubi-bd_Hrs_VPS27
IPR003903--UIM_dom
IPR002014--VHS_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50330--UIM
PS50179--VHS
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF12210--Hrs_helical
PF00790--VHS

SMART

SM00064--FYVE
SM00288--VHS

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0005764--C:lysosome
GO:0046872--F:metal ion binding
GO:0010324--P:membrane invagination
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:1903543--P:positive regulation of exosomal secretion
GO:0010628--P:positive regulation of gene expression
GO:0072657--P:protein localization to membrane
GO:0006622--P:protein targeting to lysosome
GO:0043405--P:regulation of MAP kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001518	Ailuropoda melanoleuca	79.09	0.00e+00	913.00
IUUC-Apl-003662	Anas platyrhynchos	82.01	0.00e+00	1010.00
IUUC-Ago-007931	Ashbya gossypii	32.21	2.00e-27	116.00
IUUC-Acl-008274	Aspergillus clavatus	30.74	2.00e-38	154.00
IUUC-Afl-008521	Aspergillus flavus	32.81	6.00e-39	155.00
IUUC-Afu-008774	Aspergillus fumigatus	31.85	7.00e-39	155.00
IUUC-Ani-009445	Aspergillus nidulans	31.85	2.00e-40	160.00
IUUC-Ang-009863	Aspergillus niger	33.09	3.00e-41	162.00
IUUC-Ate-010444	Aspergillus terreus	34.07	3.00e-41	162.00
IUUC-Ame-011111	Astyanax mexicanus	78.76	0.00e+00	961.00
IUUC-Bgr-012087	Blumeria graminis	34.66	2.00e-42	167.00
IUUC-Bta-012506	Bos taurus	83.49	0.00e+00	1092.00
IUUC-Bci-013782	Botrytis cinerea	33.46	2.00e-40	160.00
IUUC-Cel-018493	Caenorhabditis elegans	54.29	2.00e-69	256.00
IUUC-Cja-019998	Callithrix jacchus	79.52	0.00e+00	991.00
IUUC-Cfa-020615	Canis familiaris	82.32	0.00e+00	1004.00
IUUC-Cpo-022019	Cavia porcellus	81.12	0.00e+00	1117.00
IUUC-Csa-023596	Chlorocebus sabaeus	81.55	0.00e+00	1016.00
IUUC-Cin-025488	Ciona intestinalis	47.34	2.00e-128	452.00
IUUC-Csv-025802	Ciona savignyi	50.74	2.00e-115	409.00
IUUC-Cgl-026560	Colletotrichum gloeosporioides	35.16	5.00e-40	159.00
IUUC-Cne-026847	Cryptococcus neoformans	32.06	4.00e-38	152.00
IUUC-Dre-028353	Danio rerio	78.61	0.00e+00	937.00
IUUC-Dno-029005	Dasypus novemcinctus	80.10	0.00e+00	1061.00
IUUC-Dor-030280	Dipodomys ordii	81.49	0.00e+00	1058.00
IUUC-Dse-031238	Dothistroma septosporum	38.25	2.00e-42	167.00
IUUC-Dme-031952	Drosophila melanogaster	46.07	6.00e-101	361.00
IUUC-Ete-032235	Echinops telfairi	95.45	3.00e-131	462.00
IUUC-Eca-033873	Equus caballus	83.61	0.00e+00	1070.00
IUUC-Eeu-034652	Erinaceus europaeus	93.85	2.00e-103	370.00
IUUC-Fca-036563	Felis catus	81.77	0.00e+00	1046.00
IUUC-Fal-036649	Ficedula albicollis	84.36	0.00e+00	1083.00
IUUC-Fox-037962	Fusarium oxysporum	33.09	7.00e-39	155.00
IUUC-Fso-038396	Fusarium solani	33.70	2.00e-39	157.00
IUUC-Gmo-039510	Gadus morhua	75.76	0.00e+00	963.00
IUUC-Ggr-039938	Gaeumannomyces graminis	28.89	5.00e-37	149.00
IUUC-Gga-040201	Gallus gallus	83.80	0.00e+00	1162.00
IUUC-Gac-041459	Gasterosteus aculeatus	71.93	0.00e+00	968.00
IUUC-Ggo-044573	Gorilla gorilla	81.99	0.00e+00	1068.00
IUUC-Hsa-046009	Homo sapiens	82.12	0.00e+00	1113.00
IUUC-Itr-049065	Ictidomys tridecemlineatus	82.19	0.00e+00	1133.00
IUUC-Kpa-049327	Komagataella pastoris	30.83	8.00e-34	138.00
IUUC-Lch-049944	Latimeria chalumnae	76.63	1.00e-161	562.00
IUUC-Loc-051850	Lepisosteus oculatus	79.38	0.00e+00	1038.00
IUUC-Lma-053252	Leptosphaeria maculans	36.07	5.00e-41	162.00
IUUC-Laf-053346	Loxodonta africana	75.34	0.00e+00	961.00
IUUC-Mcc-055789	Macaca mulatta	83.13	0.00e+00	1064.00
IUUC-Meu-056329	Macropus eugenii	66.59	1.00e-155	543.00
IUUC-Mor-057205	Magnaporthe oryzae	33.90	4.00e-38	152.00
IUUC-Mpo-057295	Magnaporthe poae	32.12	1.00e-38	154.00
IUUC-Mla-058849	Melampsora laricipopulina	32.03	7.00e-32	132.00
IUUC-Mga-059361	Meleagris gallopavo	83.31	0.00e+00	1098.00
IUUC-Mvi-060561	Microbotryum violaceum	38.63	1.00e-39	157.00
IUUC-Mmr-061122	Microcebus murinus	87.84	0.00e+00	938.00
IUUC-Mdo-062171	Monodelphis domestica	84.14	0.00e+00	1164.00
IUUC-Mmu-063952	Mus musculus	82.49	0.00e+00	1153.00
IUUC-Mpu-065852	Mustela putorius furo	81.77	0.00e+00	1013.00
IUUC-Mlu-066996	Myotis lucifugus	72.88	4.00e-129	454.00
IUUC-Nfi-068539	Neosartorya fischeri	31.85	4.00e-39	156.00
IUUC-Ncr-068726	Neurospora crassa	39.91	1.00e-39	157.00
IUUC-Nle-070148	Nomascus leucogenys	78.14	0.00e+00	963.00
IUUC-Opr-070833	Ochotona princeps	67.89	0.00e+00	721.00
IUUC-Ont-071261	Oreochromis niloticus	78.14	0.00e+00	971.00
IUUC-Oan-073684	Ornithorhynchus anatinus	71.36	1.00e-161	562.00
IUUC-Ola-087570	Oryzias latipes	75.34	0.00e+00	990.00
IUUC-Oga-089087	Otolemur garnettii	79.40	0.00e+00	971.00
IUUC-Oar-089534	Ovis aries	83.76	0.00e+00	1093.00
IUUC-Ptr-091654	Pan troglodytes	76.83	0.00e+00	960.00
IUUC-Pan-092652	Papio anubis	82.06	0.00e+00	1068.00
IUUC-Pno-095125	Phaeosphaeria nodorum	36.77	2.00e-41	163.00
IUUC-Pfo-096757	Poecilia formosa	77.42	0.00e+00	939.00
IUUC-Pab-097788	Pongo abelii	85.77	0.00e+00	765.00
IUUC-Pca-100145	Procavia capensis	72.74	0.00e+00	872.00
IUUC-Pva-102965	Pteropus vampyrus	80.91	0.00e+00	1024.00
IUUC-Pgr-103609	Puccinia graminis	29.94	2.00e-34	139.00
IUUC-Ptt-103865	Puccinia triticina	34.90	8.00e-34	139.00
IUUC-Pte-104095	Pyrenophora teres	36.61	1.00e-41	164.00
IUUC-Pyt-104668	Pyrenophora triticirepentis	36.77	3.00e-41	163.00
IUUC-Rno-105125	Rattus norvegicus	83.62	0.00e+00	1073.00
IUUC-Sce-106192	Saccharomyces cerevisiae	29.28	2.00e-27	117.00
IUUC-Sha-107066	Sarcophilus harrisii	85.50	0.00e+00	1112.00
IUUC-Sja-107931	Schizosaccharomyces japonicus	33.70	2.00e-41	164.00
IUUC-Spo-108220	Schizosaccharomyces pombe	33.21	8.00e-38	151.00
IUUC-Stu-112464	Solanum tuberosum	45.90	2.00e-13	71.60
IUUC-Sar-113393	Sorex araneus	91.05	4.00e-106	378.00
IUUC-Sre-114986	Sporisorium reilianum	38.57	7.00e-42	165.00
IUUC-Tgu-117505	Taeniopygia guttata	84.67	0.00e+00	1066.00
IUUC-Tru-118494	Takifugu rubripes	78.43	0.00e+00	1016.00
IUUC-Tsy-119626	Tarsius syrichta	93.81	1.00e-51	197.00
IUUC-Tni-120174	Tetraodon nigroviridis	73.25	0.00e+00	1010.00
IUUC-Tre-122191	Trichoderma reesei	33.82	2.00e-40	160.00
IUUC-Tvi-122318	Trichoderma virens	32.98	7.00e-41	162.00
IUUC-Tme-126914	Tuber melanosporum	34.29	4.00e-43	169.00
IUUC-Ttr-129095	Tursiops truncatus	84.05	0.00e+00	1110.00
IUUC-Uma-129475	Ustilago maydis	36.61	1.00e-38	154.00
IUUC-Vda-129908	Verticillium dahliae	33.09	2.00e-35	144.00
IUUC-Xtr-131900	Xenopus tropicalis	78.17	0.00e+00	1063.00
IUUC-Xma-133124	Xiphophorus maculatus	77.52	0.00e+00	988.00
IUUC-Yli-134682	Yarrowia lipolytica	35.27	1.00e-32	134.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence