iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000000536.1	ENSONIT00000000681.1	ENSONIP00000000682.1
ENSONIG00000000536.1	ENSONIT00000000682.1	ENSONIP00000000683.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.00e-51	173.2	1146	1198

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+++ydy+a+n+deL++ kG  + ++  ++++ +W+kg  e++   Gl+P n+v+ 
   Q: 1146 QVIAMYDYTAANQDELSFSKGQLINIL--DKTNPDWWKG--EANRVTGLLPTNYVKM 1198
           6899***********************..99********..9*************85 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

TVSRFCPGGA SVWAVTPEER AKHDKQFETL SPVLGYISGE QARKFFLQSG LPASVLAEIW 60
NLADMDSDGK MDKLEFSIAM KLIKLKLQGR NLPSALPVVM KQPPASNCGS TIASSARFGM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCATGTTAC CTGCATGTGC TTATCTGCTC CCGGGACAAT GCCAAAGATC CCATCAATTA 60
ATCTCATCAG ATGGGCCAGG CTCCCTGTTG GCATACCACT TTAGATGCTG ACTGCACCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR001331--GDS_CDC24_CS
IPR027029--Intersectin-2
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain
IPR013315--Spectrin_alpha_SH3

PROSITE

PS50004--C2
PS00741--DH_1
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN
PR01887--SPECTRNALPHA

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011759	Astyanax mexicanus	68.83	0.00e+00	1300.00
IUUC-Bta-013248	Bos taurus	63.86	0.00e+00	1204.00
IUUC-Cfa-020628	Canis familiaris	64.70	0.00e+00	1222.00
IUUC-Csa-023122	Chlorocebus sabaeus	64.87	0.00e+00	1220.00
IUUC-Cne-026918	Cryptococcus neoformans	36.81	2.00e-40	162.00
IUUC-Dre-027849	Danio rerio	74.02	0.00e+00	1168.00
IUUC-Eeu-034972	Erinaceus europaeus	44.30	1.00e-105	378.00
IUUC-Gmo-039555	Gadus morhua	81.81	0.00e+00	1278.00
IUUC-Gac-041320	Gasterosteus aculeatus	84.38	0.00e+00	1396.00
IUUC-Hsa-046833	Homo sapiens	64.92	0.00e+00	1223.00
IUUC-Mcc-054709	Macaca mulatta	64.61	0.00e+00	1223.00
IUUC-Mvi-060268	Microbotryum violaceum	31.03	3.00e-47	185.00
IUUC-Mmr-060891	Microcebus murinus	65.02	0.00e+00	1242.00
IUUC-Mmu-064226	Mus musculus	62.45	0.00e+00	1233.00
IUUC-Mpu-066431	Mustela putorius furo	64.56	0.00e+00	1222.00
IUUC-Ola-087489	Oryzias latipes	75.13	0.00e+00	1422.00
IUUC-Oga-088449	Otolemur garnettii	64.81	0.00e+00	1214.00
IUUC-Oar-090275	Ovis aries	64.17	0.00e+00	1224.00
IUUC-Ptr-091667	Pan troglodytes	64.95	0.00e+00	1215.00
IUUC-Pfo-096864	Poecilia formosa	77.58	0.00e+00	1431.00
IUUC-Pab-098755	Pongo abelii	61.78	0.00e+00	1147.00
IUUC-Ppe-101928	Prunus persica	47.62	1.00e-11	66.20
IUUC-Pgr-103473	Puccinia graminis	32.08	1.00e-40	163.00
IUUC-Ptt-103973	Puccinia triticina	26.48	7.00e-30	127.00
IUUC-Rno-105691	Rattus norvegicus	63.42	0.00e+00	1254.00
IUUC-Sar-112978	Sorex araneus	57.46	0.00e+00	636.00
IUUC-Tru-117936	Takifugu rubripes	90.31	0.00e+00	1294.00
IUUC-Tni-119958	Tetraodon nigroviridis	77.10	0.00e+00	1467.00
IUUC-Ttr-129196	Tursiops truncatus	61.20	0.00e+00	1158.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence