iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005048

UUCD1 version

UUC-AnC-00303

Ensembl Protein ID

ENSACAP00000014933.2

UniProt Accession

H9GM08; H9GM08_ANOCA

Protein Name

Coronin

Gene Name

CORO1A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000015112.2	ENSACAT00000015236.2	ENSACAP00000014933.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.50e-19	68.1	79	112

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlr 31
           gHt++v ++++   +d+ ++sGs D++++vW + 
   Q: 79   GHTGPVLDVEWcphNDNVIASGSEDCSVMVWAVP 112
           8***********9877***************976 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSRKVVRSSK FRHVYGQPAK ADQCYDDIRV SQMTWDGNFC SVNPKFLAIV VEASGGGAFL 60
VLPLAKTGRL DKSYPLVSGH TGPVLDVEWC PHNDNVIASG SEDCSVMVWA VPETGLIRSL 120

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Nucleotide Sequence
(Fasta)

ATGAGCCGTA AAGTTGTGAG GTCCAGCAAG TTTCGCCATG TCTACGGACA GCCGGCCAAG 60
GCTGATCAGT GTTACGATGA CATCCGTGTC TCTCAGATGA CCTGGGATGG GAATTTCTGC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR029508--CORO1A
IPR015505--Coronin
IPR015048--DUF1899
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005884--C:actin filament
GO:0030424--C:axon
GO:0005911--C:cell-cell junction
GO:0030864--C:cortical actin cytoskeleton
GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0001772--C:immunological synapse
GO:0030027--C:lamellipodium
GO:0001891--C:phagocytic cup
GO:0045335--C:phagocytic vesicle
GO:0043234--C:protein complex
GO:0051015--F:actin filament binding
GO:0003723--F:RNA binding
GO:0030036--P:actin cytoskeleton organization
GO:0007015--P:actin filament organization
GO:0006816--P:calcium ion transport
GO:0031589--P:cell-substrate adhesion
GO:0071353--P:cellular response to interleukin-4
GO:0061502--P:early endosome to recycling endosome transport
GO:0048873--P:homeostasis of number of cells within a tissue
GO:0030595--P:leukocyte chemotaxis
GO:0043320--P:natural killer cell degranulation
GO:0051126--P:negative regulation of actin nucleation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0031339--P:negative regulation of vesicle fusion
GO:0038180--P:nerve growth factor signaling pathway
GO:0001845--P:phagolysosome assembly
GO:0050918--P:positive chemotaxis
GO:0030335--P:positive regulation of cell migration
GO:0042102--P:positive regulation of T cell proliferation
GO:0008360--P:regulation of cell shape
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol
GO:0043029--P:T cell homeostasis
GO:0032796--P:uropod organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-013168	Bos taurus	66.81	0.00e+00	676.00
IUUC-Bci-013935	Botrytis cinerea	43.95	2.00e-99	356.00
IUUC-Cja-019660	Callithrix jacchus	66.39	0.00e+00	676.00
IUUC-Cfa-020938	Canis familiaris	66.60	0.00e+00	676.00
IUUC-Csa-023193	Chlorocebus sabaeus	66.39	0.00e+00	673.00
IUUC-Cne-026773	Cryptococcus neoformans	39.66	1.00e-84	307.00
IUUC-Eca-034229	Equus caballus	65.97	0.00e+00	671.00
IUUC-Fso-038184	Fusarium solani	44.06	1.00e-97	350.00
IUUC-Ggo-045162	Gorilla gorilla	66.39	0.00e+00	673.00
IUUC-Hsa-046874	Homo sapiens	66.39	0.00e+00	673.00
IUUC-Lma-053160	Leptosphaeria maculans	43.69	7.00e-97	347.00
IUUC-Mla-058883	Melampsora laricipopulina	44.55	1.00e-89	323.00
IUUC-Mmr-060858	Microcebus murinus	66.39	0.00e+00	674.00
IUUC-Mdo-062469	Monodelphis domestica	68.63	0.00e+00	681.00
IUUC-Mmu-063583	Mus musculus	67.01	0.00e+00	674.00
IUUC-Ncr-068781	Neurospora crassa	43.07	7.00e-98	351.00
IUUC-Nle-069815	Nomascus leucogenys	66.60	0.00e+00	676.00
IUUC-Opr-070911	Ochotona princeps	67.01	0.00e+00	674.00
IUUC-Oar-089676	Ovis aries	67.01	0.00e+00	679.00
IUUC-Ptr-091647	Pan troglodytes	66.39	0.00e+00	674.00
IUUC-Pan-092672	Papio anubis	66.39	0.00e+00	673.00
IUUC-Pno-094994	Phaeosphaeria nodorum	43.69	2.00e-96	346.00
IUUC-Pva-102668	Pteropus vampyrus	66.81	0.00e+00	677.00
IUUC-Pgr-103354	Puccinia graminis	42.96	7.00e-93	334.00
IUUC-Ptt-103735	Puccinia triticina	36.18	9.00e-71	260.00
IUUC-Pte-104194	Pyrenophora teres	41.79	5.00e-94	338.00
IUUC-Pyt-104437	Pyrenophora triticirepentis	41.99	5.00e-94	338.00
IUUC-Rno-105604	Rattus norvegicus	68.06	0.00e+00	677.00
IUUC-Spo-108364	Schizosaccharomyces pombe	43.55	3.00e-97	348.00
IUUC-Ttr-128689	Tursiops truncatus	66.60	0.00e+00	675.00
IUUC-Uma-129489	Ustilago maydis	38.74	2.00e-82	299.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence