iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115980

Ensembl Protein ID

ENSSSCP00000013737.2

UniProt Accession

F1RUX1; F1RUX1_PIG

Genbank Protein ID

ENSSSCP00000013737

Protein Name

Coronin

Genbank Nucleotide ID

CU633429

Gene Name

CORO1B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000012920.2	ENSSSCT00000014123.2	ENSSSCP00000013737.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.00e-16	58.8	79	111

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt++v ++++   +d  ++sGs D+t++vW +
   Q: 79   GHTGPVLDIDWcphNDEVIASGSEDCTVMVWQI 111
           8***********977799*************86 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MFRKVVRQSK FRHVFGQPVK NDQCYEDIRV SRVTWDSTFC AVNPKFLAVI VEASGGGAFL 60
VLPLSKTGRI DKAYPTVCGH TGPVLDIDWC PHNDEVIASG SEDCTVMVWQ IPEHGLTSPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNCCGCC CCCCCCGCCC CCCAGCTCCT CTGTCATTTC CTGATTCCCG CTTCCTGCTT 60
CCCAGAGACT GGGATCCGGA GCCACCCGAG GACGGTGCTG CAGCCCCCGG GCGTCCCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005884--C:actin filament
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0001725--C:stress fiber
GO:0051015--F:actin filament binding
GO:0030036--P:actin cytoskeleton organization
GO:0090135--P:actin filament branching
GO:0051017--P:actin filament bundle assembly
GO:0036120--P:cellular response to platelet-derived growth factor stimulus
GO:0035767--P:endothelial cell chemotaxis
GO:0034316--P:negative regulation of Arp2/3 complex-mediated actin nucleation
GO:0071672--P:negative regulation of smooth muscle cell chemotaxis
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:1902463--P:protein localization to cell leading edge
GO:0031529--P:ruffle organization
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002423	Ailuropoda melanoleuca	92.35	0.00e+00	938.00
IUUC-Aca-005056	Anolis carolinensis	79.13	0.00e+00	811.00
IUUC-Bta-012984	Bos taurus	92.57	0.00e+00	952.00
IUUC-Cja-019498	Callithrix jacchus	90.34	0.00e+00	915.00
IUUC-Cfa-020937	Canis familiaris	93.08	0.00e+00	863.00
IUUC-Cpo-021866	Cavia porcellus	86.32	0.00e+00	871.00
IUUC-Csa-023561	Chlorocebus sabaeus	91.15	0.00e+00	921.00
IUUC-Cne-026773	Cryptococcus neoformans	35.45	3.00e-78	286.00
IUUC-Dno-029770	Dasypus novemcinctus	85.17	0.00e+00	857.00
IUUC-Dor-030989	Dipodomys ordii	90.14	0.00e+00	899.00
IUUC-Eca-033901	Equus caballus	92.56	0.00e+00	908.00
IUUC-Fca-036494	Felis catus	92.35	0.00e+00	896.00
IUUC-Fal-036737	Ficedula albicollis	80.61	0.00e+00	818.00
IUUC-Ggo-045035	Gorilla gorilla	91.55	0.00e+00	922.00
IUUC-Hsa-046154	Homo sapiens	90.95	0.00e+00	917.00
IUUC-Itr-048847	Ictidomys tridecemlineatus	90.34	0.00e+00	894.00
IUUC-Laf-054566	Loxodonta africana	89.13	0.00e+00	878.00
IUUC-Mcc-054879	Macaca mulatta	90.95	0.00e+00	918.00
IUUC-Meu-056083	Macropus eugenii	65.17	0.00e+00	655.00
IUUC-Mvi-060569	Microbotryum violaceum	38.73	4.00e-86	311.00
IUUC-Mmr-060910	Microcebus murinus	90.34	0.00e+00	919.00
IUUC-Mmu-063455	Mus musculus	91.13	0.00e+00	925.00
IUUC-Mpu-066350	Mustela putorius furo	92.15	0.00e+00	909.00
IUUC-Mlu-067353	Myotis lucifugus	93.32	0.00e+00	920.00
IUUC-Nle-069161	Nomascus leucogenys	91.15	0.00e+00	914.00
IUUC-Opr-071106	Ochotona princeps	88.73	0.00e+00	885.00
IUUC-Oga-088805	Otolemur garnettii	90.14	0.00e+00	918.00
IUUC-Ptr-091484	Pan troglodytes	90.95	0.00e+00	917.00
IUUC-Pan-091843	Papio anubis	90.74	0.00e+00	910.00
IUUC-Pab-097835	Pongo abelii	91.35	0.00e+00	919.00
IUUC-Pca-100411	Procavia capensis	80.08	0.00e+00	792.00
IUUC-Pva-102659	Pteropus vampyrus	90.74	0.00e+00	914.00
IUUC-Rno-106070	Rattus norvegicus	89.94	0.00e+00	917.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence