iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048319

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01007449

Gene Name

USP48

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000010287.2	ENSSTOT00000010293.2	ENSSTOP00000009236.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.10e-73	246.9	89	419
ULD/UDP/UBQ/UBQ_Other	2.40e-10	40.2	965	1027

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle........kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkea 81
           +Gl+Nlg+tCY+N  LQ+ +   elr++l               ++ee+ + + ++++++lq lf+ l++s++++++p+ ++kal+   
   Q: 89   VGLTNLGATCYVNTFLQVWFLNLELRQALYLcpstcsdyIMGDGVQEEK-DYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKALG--- 173
           6*****************************9666665554444444433.67888******************************9... PP
   S: 82   eefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfl 170
             +++ +qqDaqEf + +++ le++l                       +++k+   ++++++ F g++   ++c++c+++s+  ++f+
   Q: 174  --LDTGQQQDAQEFSKLFMSLLEDTL-----------------------SKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFY 237
           ..78899*******************.......................457889999******************************* PP
   S: 171  dlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleL 259
           +l+l+++g++     +l+dc+++f kee+leg+n+y+ce+c++kq+a++k++l +lP +L l+L+Rf f++++++++k+n+++ f + L
   Q: 238  ELELNIQGHK-----QLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSEIL 321
           **********.....9************************************************************************* PP
   S: 260  dlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg................... 327
           d++p+++++      ++ YeL+av++H G s+ sGHY+a+vk+ ++g+W++f+D+ +++++ ++ +   +                   
   Q: 322  DMEPYVEHKGG----SYAYELSAVLIHRGvSAYSGHYIAHVKDpQSGEWYKFNDEDIEKMEGKKLQLGIEedlaepsksqtrkpkcgkg 406
           ******99554....79**************************44555************9999998665999**************** PP
   S: 328  ....staYvlfYk 336
               ++aY+l+Y+
   Q: 407  thcsRNAYMLVYR 419
           ************8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 16   k...vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
           k   v+   t +eLK +i +++++ p +q+L ++Gk+L +d+ tL+ +g+ ++s+i+l  +++
   Q: 965  KaliVSANQTLKELKIQIMHAFSVAPFDQNLSIDGKVLsDDCATLGTLGVIPESVILLKADEP 1027
           344488999************************************************988775 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MAPRLQLEKA AWRWAETVRP EEVSQEHIET AYRIWLEPCI RGVCRRNCKG NPNCLVGIGE 60
HIWLGEIDEN SFHNIDDPNC ERRKKNSFVG LTNLGATCYV NTFLQVWFLN LELRQALYLC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCTCGTTG TGCCAGGGCC ATGGCCCCGC GGCTGCAGCT GGAGAAGGCG GCCTGGCGCT 60
GGGCGGAGAC GGTGCGGCCC GAGGAGGTGT CGCAGGAGCA CATCGAGACC GCCTACCGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	32.50	3.00e-81	296.00
IUUC-Aml-001357	Ailuropoda melanoleuca	95.74	0.00e+00	2040.00
IUUC-Atr-002976	Amborella trichopoda	32.09	8.00e-78	285.00
IUUC-Apl-003773	Anas platyrhynchos	85.52	0.00e+00	1668.00
IUUC-Aca-004466	Anolis carolinensis	81.07	0.00e+00	868.00
IUUC-Aly-006249	Arabidopsis lyrata	29.72	7.00e-71	262.00
IUUC-Ath-006700	Arabidopsis thaliana	31.11	3.00e-80	293.00
IUUC-Ame-011554	Astyanax mexicanus	68.06	0.00e+00	1441.00
IUUC-Bta-012573	Bos taurus	94.61	0.00e+00	2035.00
IUUC-Bdi-014149	Brachypodium distachyon	32.64	3.00e-82	300.00
IUUC-Bol-016289	Brassica oleracea	29.78	5.00e-78	286.00
IUUC-Bra-017205	Brassica rapa	29.32	6.00e-71	262.00
IUUC-Cel-018662	Caenorhabditis elegans	27.73	3.00e-28	120.00
IUUC-Cja-019991	Callithrix jacchus	94.11	0.00e+00	2043.00
IUUC-Cfa-020294	Canis familiaris	95.92	0.00e+00	2080.00
IUUC-Cpo-021706	Cavia porcellus	92.98	0.00e+00	1928.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	32.22	3.00e-43	171.00
IUUC-Csa-023931	Chlorocebus sabaeus	95.45	0.00e+00	2061.00
IUUC-Cho-024566	Choloepus hoffmanni	90.20	2.00e-156	546.00
IUUC-Cin-025307	Ciona intestinalis	47.16	8.00e-76	276.00
IUUC-Csv-026006	Ciona savignyi	37.28	4.00e-153	535.00
IUUC-Cne-027065	Cryptococcus neoformans	28.70	9.00e-67	248.00
IUUC-Dre-027624	Danio rerio	68.25	0.00e+00	1483.00
IUUC-Dno-029633	Dasypus novemcinctus	96.86	0.00e+00	1312.00
IUUC-Dor-030809	Dipodomys ordii	75.38	0.00e+00	1206.00
IUUC-Ete-032818	Echinops telfairi	91.50	0.00e+00	955.00
IUUC-Eca-033692	Equus caballus	95.73	0.00e+00	2063.00
IUUC-Eeu-035185	Erinaceus europaeus	71.45	0.00e+00	783.00
IUUC-Fca-035676	Felis catus	95.54	0.00e+00	2074.00
IUUC-Fal-036913	Ficedula albicollis	84.38	0.00e+00	1807.00
IUUC-Gmo-038532	Gadus morhua	65.46	0.00e+00	1392.00
IUUC-Gga-041041	Gallus gallus	84.75	0.00e+00	1805.00
IUUC-Gac-042570	Gasterosteus aculeatus	66.85	0.00e+00	1440.00
IUUC-Gma-044136	Glycine max	30.38	2.00e-91	330.00
IUUC-Ggo-045367	Gorilla gorilla	90.44	0.00e+00	1921.00
IUUC-Hsa-046019	Homo sapiens	95.45	0.00e+00	2063.00
IUUC-Hvu-047303	Hordeum vulgare	33.77	2.00e-66	246.00
IUUC-Lch-049989	Latimeria chalumnae	75.14	0.00e+00	1638.00
IUUC-Lpe-051612	Leersia perrieri	32.60	9.00e-80	291.00
IUUC-Loc-052756	Lepisosteus oculatus	71.30	0.00e+00	1543.00
IUUC-Laf-054043	Loxodonta africana	95.73	0.00e+00	2062.00
IUUC-Mcc-054986	Macaca mulatta	94.02	0.00e+00	2045.00
IUUC-Meu-056228	Macropus eugenii	74.67	0.00e+00	847.00
IUUC-Mtr-058762	Medicago truncatula	29.79	6.00e-88	318.00
IUUC-Mga-059896	Meleagris gallopavo	84.12	0.00e+00	1704.00
IUUC-Mvi-060269	Microbotryum violaceum	37.32	2.00e-62	234.00
IUUC-Mmr-060887	Microcebus murinus	95.45	0.00e+00	2059.00
IUUC-Mdo-062506	Monodelphis domestica	91.18	0.00e+00	1970.00
IUUC-Mmu-063642	Mus musculus	92.32	0.00e+00	2003.00
IUUC-Mac-064896	Musa acuminata	31.48	1.00e-76	281.00
IUUC-Mpu-066194	Mustela putorius furo	95.73	0.00e+00	2058.00
IUUC-Mlu-067233	Myotis lucifugus	93.98	0.00e+00	2033.00
IUUC-Nle-069052	Nomascus leucogenys	94.38	0.00e+00	2045.00
IUUC-Opr-070890	Ochotona princeps	94.92	0.00e+00	1251.00
IUUC-Ont-071450	Oreochromis niloticus	63.59	0.00e+00	1366.00
IUUC-Oan-073252	Ornithorhynchus anatinus	86.92	0.00e+00	1045.00
IUUC-Ocu-073796	Oryctolagus cuniculus	94.94	0.00e+00	1757.00
IUUC-Oba-075563	Oryza barthii	32.04	1.00e-80	295.00
IUUC-Obr-076394	Oryza brachyantha	32.28	1.00e-81	297.00
IUUC-Ogl-077339	Oryza glaberrima	38.23	4.00e-41	161.00
IUUC-Ogu-079007	Oryza glumaepatula	32.87	4.00e-74	273.00
IUUC-Oin-079997	Oryza indica	32.04	4.00e-81	296.00
IUUC-Olo-080364	Oryza longistaminata	32.04	6.00e-81	295.00
IUUC-Ome-081165	Oryza meridionalis	32.87	6.00e-75	275.00
IUUC-Oni-083026	Oryza nivara	32.04	4.00e-81	296.00
IUUC-Opu-083284	Oryza punctata	34.21	3.00e-75	276.00
IUUC-Oru-084797	Oryza rufipogon	32.04	6.00e-81	295.00
IUUC-Osa-086221	Oryza sativa	38.23	4.00e-41	161.00
IUUC-Ola-086568	Oryzias latipes	66.76	0.00e+00	1435.00
IUUC-Oga-088687	Otolemur garnettii	93.91	0.00e+00	2036.00
IUUC-Oar-090345	Ovis aries	94.67	0.00e+00	1946.00
IUUC-Ptr-090734	Pan troglodytes	95.36	0.00e+00	2060.00
IUUC-Pan-091704	Papio anubis	92.07	0.00e+00	1966.00
IUUC-Psi-092937	Pelodiscus sinensis	85.03	0.00e+00	1588.00
IUUC-Ppa-095808	Physcomitrella patens	27.15	1.00e-68	254.00
IUUC-Pab-098129	Pongo abelii	95.45	0.00e+00	2062.00
IUUC-Pop-099738	Populus trichocarpa	29.91	9.00e-77	281.00
IUUC-Pca-100647	Procavia capensis	98.18	0.00e+00	690.00
IUUC-Ppe-102091	Prunus persica	31.91	7.00e-85	308.00
IUUC-Pva-102719	Pteropus vampyrus	94.60	0.00e+00	2033.00
IUUC-Rno-105363	Rattus norvegicus	92.23	0.00e+00	2012.00
IUUC-Sha-107620	Sarcophilus harrisii	87.54	0.00e+00	1831.00
IUUC-Smo-109487	Selaginella moellendorffii	28.22	7.00e-86	311.00
IUUC-Sit-110683	Setaria italica	32.81	2.00e-81	297.00
IUUC-Sly-111377	Solanum lycopersicum	30.01	1.00e-80	294.00
IUUC-Stu-111969	Solanum tuberosum	31.61	4.00e-70	258.00
IUUC-Sar-113099	Sorex araneus	94.00	0.00e+00	1719.00
IUUC-Sbi-113833	Sorghum bicolor	42.14	7.00e-57	213.00
IUUC-Ssc-115279	Sus scrofa	87.73	0.00e+00	1348.00
IUUC-Tgu-117519	Taeniopygia guttata	82.03	0.00e+00	1659.00
IUUC-Tru-117651	Takifugu rubripes	66.05	0.00e+00	1426.00
IUUC-Tsy-119201	Tarsius syrichta	91.39	0.00e+00	1798.00
IUUC-Tni-120840	Tetraodon nigroviridis	67.63	0.00e+00	1447.00
IUUC-Tca-121674	Theobroma cacao	29.80	6.00e-86	312.00
IUUC-Tae-125814	Triticum aestivum	33.07	1.00e-81	297.00
IUUC-Tur-126599	Triticum urartu	32.86	2.00e-80	294.00
IUUC-Tbe-127782	Tupaia belangeri	84.26	0.00e+00	1739.00
IUUC-Ttr-128312	Tursiops truncatus	94.03	0.00e+00	2018.00
IUUC-Vpa-130348	Vicugna pacos	95.05	0.00e+00	1955.00
IUUC-Vvi-131353	Vitis vinifera	32.58	1.00e-83	304.00
IUUC-Xtr-132172	Xenopus tropicalis	69.05	0.00e+00	1342.00
IUUC-Xma-133263	Xiphophorus maculatus	66.54	0.00e+00	1390.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence