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Tag Content
iUUCD ID IUUC-Mor-057099
Ensembl Protein ID MGG_02660T0
UniProt Accession A4RC89; G4NJF9; NACA_MAGO7
Genbank Protein ID EHA46375.1
Protein Name Nascent polypeptide-associated complex subunit alpha; Alpha-NAC
Genbank Nucleotide ID CM001237
Gene Name EGD2; MGG_02660
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
MGG_02660 MGG_02660T0 MGG_02660T0
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/UBA 43.06 1.00e-12 67.40 IUUC-Sce-106371
UBD/Alpha-Helix/UBA 46.99 6.00e-28 118.00 IUUC-Spo-108121
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Magnaporthe oryzae
Functional Description
(View)

Functional Description



     Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Protein Sequence
(Fasta)
MANPRVEELP DEEVKKTVVD DHDDDSSSDS DGEEETNLPA GSTAVIHSRN EKKARKAIEK 60
LHLIRVDGIT RVTLRRPKNI LFVINNPEVY KSPNSGTYIV FGEAKIEDLN ASAQAAAAQQ 120
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Protein Fasta Sequence



>IUUC-Mor-057099|UBD,UBA|Magnaporthe oryzae
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Nucleotide Sequence
(Fasta)
GCTGCGGGTT GGTCGGTGGG TGAAGTTTTT GTGTGCATTG ACCACCCGCG AAATTCTAGG 60
GTTGTGAATT CTTCTGTCTC TGAGCACTTT GCGTCCCACA TCTCAGAGTG CGCTTTGGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Mor-057099|UBD,UBA|Magnaporthe oryzae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR016641--EGD2/NACA
IPR002715--Nas_poly-pep-assoc_cplx_dom

PROSITE

PS51151--NAC_AB

Pfam

PF01849--NAC

SMART

SM01407--NAC

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0015031--P:protein transport

KEGG mgr:MGG_02660
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001167 Aegilops tauschii 45.83 2.00e-24 103.00
IUUC-Aml-001719 Ailuropoda melanoleuca 55.48 2.00e-28 120.00
IUUC-Atr-002586 Amborella trichopoda 41.10 7.00e-20 88.60
IUUC-Apl-003190 Anas platyrhynchos 49.04 2.00e-27 112.00
IUUC-Aca-005265 Anolis carolinensis 54.84 1.00e-32 130.00
IUUC-Aly-006488 Arabidopsis lyrata 48.61 3.00e-26 109.00
IUUC-Ath-007378 Arabidopsis thaliana 50.00 6.00e-25 105.00
IUUC-Ago-007936 Ashbya gossypii 41.92 8.00e-26 107.00
IUUC-Acl-008036 Aspergillus clavatus 69.16 3.00e-32 129.00
IUUC-Afl-008462 Aspergillus flavus 60.00 5.00e-46 175.00
IUUC-Afu-008832 Aspergillus fumigatus 67.29 4.00e-29 119.00
IUUC-Ani-009246 Aspergillus nidulans 69.09 7.00e-34 134.00
IUUC-Ang-009808 Aspergillus niger 67.29 4.00e-32 129.00
IUUC-Aor-009972 Aspergillus oryzae 60.00 5.00e-46 175.00
IUUC-Ame-011674 Astyanax mexicanus 54.84 3.00e-33 132.00
IUUC-Bgr-012162 Blumeria graminis 52.51 4.00e-42 162.00
IUUC-Bta-012508 Bos taurus 54.84 8.00e-33 131.00
IUUC-Bci-013643 Botrytis cinerea 68.42 3.00e-32 129.00
IUUC-Bdi-014874 Brachypodium distachyon 43.06 1.00e-22 97.40
IUUC-Bol-015132 Brassica oleracea 50.00 9.00e-27 111.00
IUUC-Bra-017540 Brassica rapa 51.39 1.00e-25 108.00
IUUC-Cel-018111 Caenorhabditis elegans 48.77 2.00e-32 130.00
IUUC-Cja-019846 Callithrix jacchus 45.09 3.00e-27 116.00
IUUC-Cfa-020429 Canis familiaris 54.84 8.00e-33 131.00
IUUC-Cpo-021659 Cavia porcellus 48.39 4.00e-27 115.00
IUUC-Cre-022679 Chlamydomonas reinhardtii 48.39 1.00e-31 127.00
IUUC-Csa-023260 Chlorocebus sabaeus 49.08 2.00e-26 113.00
IUUC-Cho-024869 Choloepus hoffmanni 70.27 2.00e-10 57.00
IUUC-Cin-025166 Ciona intestinalis 53.55 3.00e-31 126.00
IUUC-Csv-026284 Ciona savignyi 52.78 2.00e-23 99.80
IUUC-Cgl-026520 Colletotrichum gloeosporioides 79.28 2.00e-41 159.00
IUUC-Cne-026920 Cryptococcus neoformans 40.88 9.00e-28 114.00
IUUC-Cme-027301 Cyanidioschyzon merolae 40.48 1.00e-19 87.80
IUUC-Dre-028709 Danio rerio 54.84 1.00e-32 133.00
IUUC-Dno-029786 Dasypus novemcinctus 55.48 6.00e-29 122.00
IUUC-Dor-030962 Dipodomys ordii 54.84 1.00e-32 130.00
IUUC-Dme-032061 Drosophila melanogaster 52.56 1.00e-24 104.00
IUUC-Ete-032965 Echinops telfairi 54.19 5.00e-32 129.00
IUUC-Eca-034049 Equus caballus 54.19 5.00e-32 129.00
IUUC-Eeu-034673 Erinaceus europaeus 54.84 7.00e-33 131.00
IUUC-Fca-036369 Felis catus 55.48 1.00e-28 120.00
IUUC-Fal-037006 Ficedula albicollis 54.84 3.00e-32 129.00
IUUC-Fox-037704 Fusarium oxysporum 70.28 7.00e-58 214.00
IUUC-Fso-038247 Fusarium solani 73.58 9.00e-60 221.00
IUUC-Gmo-039002 Gadus morhua 50.97 6.00e-30 122.00
IUUC-Ggr-039888 Gaeumannomyces graminis 78.64 6.00e-65 238.00
IUUC-Gga-040237 Gallus gallus 54.84 1.00e-32 130.00
IUUC-Gac-041800 Gasterosteus aculeatus 54.84 2.00e-32 132.00
IUUC-Gma-043275 Glycine max 46.10 5.00e-29 119.00
IUUC-Ggo-045163 Gorilla gorilla 47.10 2.00e-30 123.00
IUUC-Hsa-045795 Homo sapiens 55.48 1.00e-28 121.00
IUUC-Hvu-047376 Hordeum vulgare 45.83 2.00e-24 103.00
IUUC-Itr-048152 Ictidomys tridecemlineatus 54.84 7.00e-33 131.00
IUUC-Kpa-049166 Komagataella pastoris 44.94 2.00e-26 110.00
IUUC-Lch-050076 Latimeria chalumnae 54.84 6.00e-33 132.00
IUUC-Lpe-051016 Leersia perrieri 46.53 8.00e-27 111.00
IUUC-Loc-052292 Lepisosteus oculatus 55.63 5.00e-32 129.00
IUUC-Lma-053293 Leptosphaeria maculans 58.85 3.00e-47 179.00
IUUC-Laf-054393 Loxodonta africana 41.79 3.00e-31 126.00
IUUC-Mcc-054632 Macaca mulatta 55.48 1.00e-28 121.00
IUUC-Meu-056242 Macropus eugenii 53.79 4.00e-24 102.00
IUUC-Mpo-057543 Magnaporthe poae 85.00 2.00e-37 146.00
IUUC-Mtr-058769 Medicago truncatula 61.54 4.00e-16 76.30
IUUC-Mla-059166 Melampsora laricipopulina 43.59 2.00e-21 93.20
IUUC-Mga-059406 Meleagris gallopavo 54.84 3.00e-32 129.00
IUUC-Mvi-060390 Microbotryum violaceum 36.42 2.00e-19 86.70
IUUC-Mmr-061475 Microcebus murinus 49.68 6.00e-27 115.00
IUUC-Mdo-062474 Monodelphis domestica 65.62 2.00e-20 94.40
IUUC-Mmu-063984 Mus musculus 54.84 4.00e-32 133.00
IUUC-Mac-065175 Musa acuminata 49.31 1.00e-26 110.00
IUUC-Mpu-066751 Mustela putorius furo 47.67 3.00e-27 116.00
IUUC-Mlu-068234 Myotis lucifugus 54.84 7.00e-33 131.00
IUUC-Nfi-068541 Neosartorya fischeri 67.29 4.00e-29 119.00
IUUC-Ncr-068830 Neurospora crassa 69.31 1.00e-53 201.00
IUUC-Nle-069126 Nomascus leucogenys 54.84 2.00e-32 130.00
IUUC-Opr-070742 Ochotona princeps 54.84 6.00e-33 132.00
IUUC-Ont-071828 Oreochromis niloticus 54.84 1.00e-32 131.00
IUUC-Oan-073462 Ornithorhynchus anatinus 56.29 1.00e-27 117.00
IUUC-Ocu-074890 Oryctolagus cuniculus 47.10 2.00e-25 110.00
IUUC-Oba-075995 Oryza barthii 45.83 3.00e-26 109.00
IUUC-Obr-076668 Oryza brachyantha 47.22 2.00e-27 113.00
IUUC-Ogl-077307 Oryza glaberrima 46.53 4.00e-27 112.00
IUUC-Ogu-078289 Oryza glumaepatula 46.53 4.00e-27 112.00
IUUC-Oin-079287 Oryza indica 45.83 3.00e-26 109.00
IUUC-Olo-080686 Oryza longistaminata 41.10 9.00e-23 98.20
IUUC-Ome-081567 Oryza meridionalis 46.53 3.00e-27 112.00
IUUC-Oni-082873 Oryza nivara 45.83 3.00e-26 109.00
IUUC-Opu-083291 Oryza punctata 46.53 5.00e-27 112.00
IUUC-Oru-085045 Oryza rufipogon 46.53 3.00e-27 112.00
IUUC-Osa-086265 Oryza sativa 46.53 4.00e-27 112.00
IUUC-Ola-087531 Oryzias latipes 54.84 4.00e-33 132.00
IUUC-Olu-087895 Ostreococcus lucimarinus 38.19 9.00e-23 96.70
IUUC-Oga-088239 Otolemur garnettii 54.84 7.00e-33 131.00
IUUC-Oar-089723 Ovis aries 55.48 3.00e-28 119.00
IUUC-Ptr-090481 Pan troglodytes 48.82 4.00e-25 109.00
IUUC-Pan-092223 Papio anubis 55.48 4.00e-29 122.00
IUUC-Psi-093588 Pelodiscus sinensis 54.84 7.00e-33 131.00
IUUC-Pma-094702 Petromyzon marinus 51.28 9.00e-32 128.00
IUUC-Pno-094927 Phaeosphaeria nodorum 67.27 9.00e-37 144.00
IUUC-Ppa-095389 Physcomitrella patens 61.29 7.00e-19 85.10
IUUC-Pfo-096744 Poecilia formosa 54.84 2.00e-33 133.00
IUUC-Pab-098044 Pongo abelii 54.84 7.00e-33 131.00
IUUC-Pop-099384 Populus trichocarpa 50.00 1.00e-32 130.00
IUUC-Pca-100355 Procavia capensis 49.03 2.00e-27 116.00
IUUC-Ppe-101786 Prunus persica 49.31 4.00e-27 112.00
IUUC-Pva-102494 Pteropus vampyrus 54.84 6.00e-33 132.00
IUUC-Pgr-103303 Puccinia graminis 44.10 1.00e-22 97.40
IUUC-Ptt-103748 Puccinia triticina 65.91 2.00e-11 60.10
IUUC-Pte-104368 Pyrenophora teres 68.18 8.00e-37 144.00
IUUC-Pyt-104542 Pyrenophora triticirepentis 60.77 1.00e-48 183.00
IUUC-Rno-105387 Rattus norvegicus 54.84 3.00e-32 133.00
IUUC-Sce-106371 Saccharomyces cerevisiae 40.35 1.00e-18 84.00
IUUC-Sha-107189 Sarcophilus harrisii 54.84 7.00e-33 131.00
IUUC-Sja-107942 Schizosaccharomyces japonicus 50.61 5.00e-29 118.00
IUUC-Spo-108121 Schizosaccharomyces pombe 46.75 6.00e-33 131.00
IUUC-Ssl-108595 Sclerotinia sclerotiorum 70.18 2.00e-35 140.00
IUUC-Smo-108783 Selaginella moellendorffii 48.61 3.00e-27 113.00
IUUC-Sit-109728 Setaria italica 48.61 5.00e-26 108.00
IUUC-Sly-110957 Solanum lycopersicum 47.22 6.00e-25 105.00
IUUC-Stu-112873 Solanum tuberosum 44.44 5.00e-22 95.50
IUUC-Sar-113668 Sorex araneus 70.27 3.00e-10 56.60
IUUC-Sbi-114223 Sorghum bicolor 48.61 1.00e-25 107.00
IUUC-Sre-115220 Sporisorium reilianum 50.00 8.00e-24 101.00
IUUC-Ssc-116119 Sus scrofa 54.84 7.00e-33 131.00
IUUC-Tgu-116528 Taeniopygia guttata 55.63 1.00e-31 127.00
IUUC-Tru-117538 Takifugu rubripes 55.48 3.00e-33 133.00
IUUC-Tsy-118855 Tarsius syrichta 70.27 2.00e-10 56.60
IUUC-Tni-120134 Tetraodon nigroviridis 54.84 2.00e-33 133.00
IUUC-Tca-121524 Theobroma cacao 50.69 2.00e-27 114.00
IUUC-Tre-121915 Trichoderma reesei 70.18 5.00e-36 142.00
IUUC-Tvi-122411 Trichoderma virens 71.56 6.00e-35 138.00
IUUC-Tae-124851 Triticum aestivum 45.83 2.00e-24 103.00
IUUC-Tur-126821 Triticum urartu 45.83 2.00e-24 103.00
IUUC-Tme-126875 Tuber melanosporum 61.82 1.00e-28 117.00
IUUC-Tbe-127759 Tupaia belangeri 48.61 4.00e-23 99.40
IUUC-Ttr-129124 Tursiops truncatus 53.55 7.00e-27 115.00
IUUC-Uma-129551 Ustilago maydis 47.06 4.00e-26 108.00
IUUC-Vda-129992 Verticillium dahliae 66.02 4.00e-55 205.00
IUUC-Vpa-130096 Vicugna pacos 53.55 6.00e-30 122.00
IUUC-Vvi-130940 Vitis vinifera 47.92 8.00e-24 101.00
IUUC-Xtr-132454 Xenopus tropicalis 54.84 4.00e-32 129.00
IUUC-Xma-133842 Xiphophorus maculatus 54.84 6.00e-33 132.00
IUUC-Yli-134485 Yarrowia lipolytica 55.88 2.00e-16 77.00
IUUC-Zma-135748 Zea mays 43.33 5.00e-26 108.00
Created Date 25-Jun-2017

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