iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067054

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02000879

Gene Name

ERCC8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000007222.2	ENSMLUT00000007232.2	ENSMLUP00000006598.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-29	100.6	184	218
UBD/Beta-Prp	2.00e-46	158.6	42	280

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrt 32
           gH  ++ ++++    d +l+++s D  +k+WD+r+
   Q: 184  GHRQEILAVSWsprYDYILATASADSRVKLWDVRK 218
           8**********96543678*************986 PP

UBD/Beta-Prp

   S: 51   heaevtavkfspdgk.ilvtgseDrtikvwdls........tgkcvhtlk.....ghedsvlslsfsp.sgdklvsGshdrtirvwdle 124
           h+++v++++++p +  ++++g++D++i ++dl+        t+k v ++       h++sv +++++p ++  + s s d+t++vwd++
   Q: 42   HSNGVNSLDIEPVEGrYMLSGGSDGVIVLYDLEnssrqpcyTCKAVCSVDryhpdVHKYSVETVQWYPhDTGMFTSSSFDKTLKVWDTN 130
           999*********877799***************99999999888888887777889************777****************** PP
   S: 125  tgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng.kelvsgsldgtvklwdlq. 210
           t q    ++ +++    +++   ++ +l++ G+   +v+l dlk+g++ + l+g h + +  +s+++     l+++s d++vklwd++ 
   Q: 131  TLQTADIFNFEETVYSHHMSPVATQhCLVAVGTRAPKVQLCDLKSGSCCHILQG-HRQEILAVSWSPRYdYILATASADSRVKLWDVRk 218
           *****9666666666667777777889**************************9.***********988677889*************9 PP
   S: 211  ...............tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdll 257
                          ++ +  + ++h+  v+ + f++++ +l++ + D+  r+W++ +g+++
   Q: 219  asgclitldqhngekSQAVESANTAHNGKVNGLCFTRDGLHLLTIGTDNRMRLWNSSNGENT 280
           877777777776665555577777888****************************9999876 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MLGFLSARQA GLDDPLHLRR AESTRRVLGL ELNKDRDVER IHSNGVNSLD IEPVEGRYML 60
SGGSDGVIVL YDLENSSRQP CYTCKAVCSV DRYHPDVHKY SVETVQWYPH DTGMFTSSSF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGACCGGGAT GCTAGGGTTT TTGTCGGCGC GACAAGCCGG ATTGGACGAC CCTCTTCACC 60
TACGAAGAGC GGAGTCCACA CGAAGGTATA GAAAACATTA CTTTTTTTTC TAATAGGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0016363--C:nuclear matrix
GO:0000109--C:nucleotide-excision repair complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0006979--P:response to oxidative stress
GO:0009411--P:response to UV
GO:0010165--P:response to X-ray
GO:0006283--P:transcription-coupled nucleotide-excision repair

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001170	Aegilops tauschii	31.66	3.00e-38	154.00
IUUC-Aml-002201	Ailuropoda melanoleuca	91.92	0.00e+00	764.00
IUUC-Atr-002784	Amborella trichopoda	37.07	2.00e-40	160.00
IUUC-Apl-003202	Anas platyrhynchos	80.36	0.00e+00	659.00
IUUC-Aca-004708	Anolis carolinensis	81.61	1.00e-176	612.00
IUUC-Aly-006144	Arabidopsis lyrata	30.23	5.00e-45	175.00
IUUC-Ath-006673	Arabidopsis thaliana	40.19	9.00e-46	177.00
IUUC-Acl-008195	Aspergillus clavatus	37.88	7.00e-41	161.00
IUUC-Afl-008406	Aspergillus flavus	36.44	1.00e-37	150.00
IUUC-Afu-008759	Aspergillus fumigatus	35.98	1.00e-38	154.00
IUUC-Ani-009380	Aspergillus nidulans	35.43	1.00e-40	160.00
IUUC-Ang-009820	Aspergillus niger	35.97	9.00e-38	150.00
IUUC-Aor-010092	Aspergillus oryzae	37.12	2.00e-42	166.00
IUUC-Ate-010491	Aspergillus terreus	36.30	2.00e-43	170.00
IUUC-Bta-012825	Bos taurus	93.20	0.00e+00	770.00
IUUC-Bci-013856	Botrytis cinerea	32.60	4.00e-53	202.00
IUUC-Bdi-014899	Brachypodium distachyon	34.61	1.00e-64	240.00
IUUC-Bol-015337	Brassica oleracea	32.36	2.00e-64	239.00
IUUC-Bra-018089	Brassica rapa	29.20	9.00e-45	174.00
IUUC-Cja-018725	Callithrix jacchus	92.17	0.00e+00	773.00
IUUC-Cfa-021162	Canis familiaris	92.42	0.00e+00	764.00
IUUC-Cpo-022190	Cavia porcellus	91.16	0.00e+00	764.00
IUUC-Cre-022960	Chlamydomonas reinhardtii	36.67	5.00e-39	155.00
IUUC-Csa-023610	Chlorocebus sabaeus	91.67	0.00e+00	768.00
IUUC-Cho-024689	Choloepus hoffmanni	90.54	0.00e+00	701.00
IUUC-Cin-025324	Ciona intestinalis	39.68	1.00e-81	296.00
IUUC-Csv-026059	Ciona savignyi	38.78	4.00e-75	275.00
IUUC-Cgl-026384	Colletotrichum gloeosporioides	33.54	2.00e-38	153.00
IUUC-Cme-027182	Cyanidioschyzon merolae	30.00	3.00e-13	70.50
IUUC-Dre-028696	Danio rerio	72.00	2.00e-175	608.00
IUUC-Dno-029102	Dasypus novemcinctus	93.18	0.00e+00	776.00
IUUC-Dor-030361	Dipodomys ordii	74.24	9.00e-173	599.00
IUUC-Dse-031167	Dothistroma septosporum	30.95	4.00e-44	172.00
IUUC-Ete-032856	Echinops telfairi	74.75	1.00e-173	602.00
IUUC-Eca-033611	Equus caballus	93.49	0.00e+00	667.00
IUUC-Eeu-034583	Erinaceus europaeus	70.45	7.00e-158	550.00
IUUC-Fca-036481	Felis catus	91.67	0.00e+00	759.00
IUUC-Fal-037327	Ficedula albicollis	79.41	2.00e-166	578.00
IUUC-Fox-037684	Fusarium oxysporum	30.25	1.00e-42	167.00
IUUC-Fso-038306	Fusarium solani	31.15	4.00e-54	205.00
IUUC-Gmo-039043	Gadus morhua	68.35	2.00e-163	568.00
IUUC-Ggr-039783	Gaeumannomyces graminis	27.63	5.00e-38	152.00
IUUC-Gga-041085	Gallus gallus	84.20	0.00e+00	628.00
IUUC-Gac-042328	Gasterosteus aculeatus	67.33	8.00e-158	549.00
IUUC-Gma-043004	Glycine max	33.18	3.00e-58	218.00
IUUC-Ggo-045627	Gorilla gorilla	83.58	0.00e+00	688.00
IUUC-Hsa-046028	Homo sapiens	91.67	0.00e+00	768.00
IUUC-Hvu-047678	Hordeum vulgare	41.83	1.00e-21	96.70
IUUC-Itr-048648	Ictidomys tridecemlineatus	90.91	0.00e+00	764.00
IUUC-Kpa-049386	Komagataella pastoris	28.84	6.00e-44	171.00
IUUC-Lch-050590	Latimeria chalumnae	79.02	4.00e-159	553.00
IUUC-Lpe-051725	Leersia perrieri	34.73	3.00e-37	149.00
IUUC-Loc-051788	Lepisosteus oculatus	75.51	1.00e-178	619.00
IUUC-Lma-053082	Leptosphaeria maculans	33.71	9.00e-55	207.00
IUUC-Laf-053809	Loxodonta africana	92.44	0.00e+00	777.00
IUUC-Mcc-054998	Macaca mulatta	91.46	2.00e-156	545.00
IUUC-Meu-055929	Macropus eugenii	76.13	3.00e-179	621.00
IUUC-Mor-057003	Magnaporthe oryzae	33.43	2.00e-47	183.00
IUUC-Mtr-057921	Medicago truncatula	32.26	2.00e-57	216.00
IUUC-Mga-059449	Meleagris gallopavo	65.00	4.00e-123	434.00
IUUC-Mmr-061609	Microcebus murinus	90.03	0.00e+00	721.00
IUUC-Mdo-062564	Monodelphis domestica	84.17	0.00e+00	704.00
IUUC-Mmu-063904	Mus musculus	87.66	0.00e+00	729.00
IUUC-Mac-064716	Musa acuminata	30.53	2.00e-51	196.00
IUUC-Mpu-066617	Mustela putorius furo	92.68	0.00e+00	769.00
IUUC-Nfi-068467	Neosartorya fischeri	36.11	8.00e-33	134.00
IUUC-Nle-069731	Nomascus leucogenys	91.67	0.00e+00	768.00
IUUC-Opr-070297	Ochotona princeps	65.69	1.00e-83	303.00
IUUC-Ont-072558	Oreochromis niloticus	69.33	2.00e-161	561.00
IUUC-Oan-072864	Ornithorhynchus anatinus	84.21	2.00e-26	110.00
IUUC-Ocu-074415	Oryctolagus cuniculus	92.93	0.00e+00	779.00
IUUC-Oba-075759	Oryza barthii	40.72	2.00e-43	170.00
IUUC-Obr-076387	Oryza brachyantha	39.81	1.00e-45	177.00
IUUC-Ogl-077924	Oryza glaberrima	40.91	5.00e-18	84.30
IUUC-Ogu-078186	Oryza glumaepatula	35.23	7.00e-63	234.00
IUUC-Oin-079389	Oryza indica	34.56	8.00e-47	181.00
IUUC-Olo-080916	Oryza longistaminata	28.92	5.00e-17	80.50
IUUC-Ome-081471	Oryza meridionalis	40.53	1.00e-40	160.00
IUUC-Oni-082449	Oryza nivara	40.21	1.00e-40	160.00
IUUC-Opu-083210	Oryza punctata	41.05	3.00e-43	169.00
IUUC-Oru-085159	Oryza rufipogon	41.58	1.00e-43	170.00
IUUC-Osa-085926	Oryza sativa	43.24	5.00e-34	137.00
IUUC-Ola-087084	Oryzias latipes	67.59	7.00e-165	573.00
IUUC-Olu-087853	Ostreococcus lucimarinus	29.29	1.00e-39	156.00
IUUC-Oga-089008	Otolemur garnettii	91.48	0.00e+00	767.00
IUUC-Oar-089259	Ovis aries	93.20	0.00e+00	771.00
IUUC-Ptr-091112	Pan troglodytes	90.84	0.00e+00	758.00
IUUC-Pan-092303	Papio anubis	91.41	5.00e-69	252.00
IUUC-Psi-093050	Pelodiscus sinensis	82.16	0.00e+00	694.00
IUUC-Pma-094259	Petromyzon marinus	58.66	3.00e-130	457.00
IUUC-Pno-094798	Phaeosphaeria nodorum	31.39	1.00e-51	197.00
IUUC-Ppa-095477	Physcomitrella patens	32.03	4.00e-56	212.00
IUUC-Pfo-096855	Poecilia formosa	66.92	2.00e-161	561.00
IUUC-Pab-098096	Pongo abelii	91.16	0.00e+00	764.00
IUUC-Pop-098800	Populus trichocarpa	28.01	9.00e-48	184.00
IUUC-Pca-100187	Procavia capensis	92.72	1.00e-112	399.00
IUUC-Ppe-101759	Prunus persica	29.02	3.00e-46	179.00
IUUC-Pva-102438	Pteropus vampyrus	78.54	6.00e-91	327.00
IUUC-Pte-104197	Pyrenophora teres	33.05	9.00e-50	191.00
IUUC-Pyt-104421	Pyrenophora triticirepentis	33.62	1.00e-49	190.00
IUUC-Rno-106087	Rattus norvegicus	87.41	0.00e+00	731.00
IUUC-Sce-106276	Saccharomyces cerevisiae	26.29	7.00e-12	65.50
IUUC-Sha-106831	Sarcophilus harrisii	82.16	0.00e+00	680.00
IUUC-Sja-107681	Schizosaccharomyces japonicus	32.92	2.00e-55	209.00
IUUC-Spo-108294	Schizosaccharomyces pombe	35.15	3.00e-62	232.00
IUUC-Ssl-108613	Sclerotinia sclerotiorum	33.81	1.00e-52	200.00
IUUC-Smo-109008	Selaginella moellendorffii	40.65	2.00e-75	275.00
IUUC-Sit-110300	Setaria italica	31.07	2.00e-53	203.00
IUUC-Sly-111441	Solanum lycopersicum	30.47	3.00e-44	172.00
IUUC-Stu-111995	Solanum tuberosum	31.03	6.00e-48	184.00
IUUC-Sar-113196	Sorex araneus	82.51	1.00e-126	446.00
IUUC-Sbi-113790	Sorghum bicolor	40.49	5.00e-43	168.00
IUUC-Ssc-115609	Sus scrofa	91.92	0.00e+00	771.00
IUUC-Tgu-116927	Taeniopygia guttata	79.95	0.00e+00	661.00
IUUC-Tru-118164	Takifugu rubripes	68.49	2.00e-168	585.00
IUUC-Tsy-119151	Tarsius syrichta	87.37	0.00e+00	726.00
IUUC-Tni-120896	Tetraodon nigroviridis	67.75	1.00e-159	555.00
IUUC-Tca-121592	Theobroma cacao	29.80	1.00e-46	180.00
IUUC-Tre-122023	Trichoderma reesei	34.24	8.00e-48	184.00
IUUC-Tvi-122507	Trichoderma virens	34.91	3.00e-48	186.00
IUUC-Tae-125730	Triticum aestivum	40.82	6.00e-43	168.00
IUUC-Tur-126092	Triticum urartu	31.92	4.00e-36	145.00
IUUC-Tbe-127422	Tupaia belangeri	69.46	8.00e-146	509.00
IUUC-Ttr-129097	Tursiops truncatus	89.90	0.00e+00	752.00
IUUC-Vda-130014	Verticillium dahliae	36.08	1.00e-49	190.00
IUUC-Vpa-130782	Vicugna pacos	92.19	0.00e+00	770.00
IUUC-Vvi-131494	Vitis vinifera	29.07	3.00e-47	182.00
IUUC-Xtr-132165	Xenopus tropicalis	78.11	4.00e-180	623.00
IUUC-Xma-133205	Xiphophorus maculatus	67.58	4.00e-165	573.00
IUUC-Yli-134614	Yarrowia lipolytica	33.84	6.00e-59	221.00
IUUC-Zma-135861	Zea mays	35.12	7.00e-60	224.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence