iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Post-translational Modifications (PTMs)
dbPTM
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
ULD/UBL/SUMO	SUMO	17644626; 19151129

Classification

Family	E-value	Score	Start	End
ULD/UBL/SUMO	8.90e-27	94.5	15	105

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UBL/SUMO

   S: 7    apvslkvag.............qdGsevlfklklsaqlkklmeavYvkrinldensvrfvfngqkireqetpeelevededkiellcqksGG 85
           a+++lkv+g              dG+ev f++k+s+qlkklm+a Y++r+++d ns++f+f+g++ r+++tp+ele+ed+d+i+++ +++GG
   Q: 15   AHINLKVKGqaffvvgtwlvidTDGNEVFFRIKRSTQLKKLMNA-YCDRQSVDFNSIAFLFDGRRLRAEQTPDELEMEDGDEIDAMLHQTGG 105
           7999999999999999999999**********************.**********************************************9 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Required for the massive protein sumoylation in the nucleus induced by heat shock and controlled by SIZ1.

Protein Sequence
(Fasta)

MSATPEEDKK PDQGAHINLK VKGQAFFVVG TWLVIDTDGN EVFFRIKRST QLKKLMNAYC 60
DRQSVDFNSI AFLFDGRRLR AEQTPDELEM EDGDEIDAML HQTGGGAKNG LKLFCF 116

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTCAGTCT TTTTTATTCT CTGCCGAGTC TCTCTCTCTC CCTCAAACCC TCAAGTTCTG 60
CAATCCCGCG AATCTCTCTT AGGGCTTCGC TTATATCGCA GATCGAAGTT CTTGTTTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1017--Isopeptide bond
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR022617--Rad60/SUMO-like_dom
IPR033950--Sumo
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF11976--Rad60-SLD

SMART

SM00213--UBQ

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0016925--P:protein sumoylation

KEGG

ath:AT5G55160

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001056	Aegilops tauschii	78.70	2.00e-43	166.00
IUUC-Aly-005765	Arabidopsis lyrata	86.21	4.00e-52	194.00
IUUC-Afu-008969	Aspergillus fumigatus	44.23	2.00e-21	92.80
IUUC-Bgr-012250	Blumeria graminis	35.78	1.00e-16	77.40
IUUC-Cho-024767	Choloepus hoffmanni	47.14	4.00e-15	72.80
IUUC-Cne-027072	Cryptococcus neoformans	53.85	7.00e-16	74.30
IUUC-Dse-031390	Dothistroma septosporum	44.95	9.00e-20	87.40
IUUC-Gma-043788	Glycine max	81.48	2.00e-46	176.00
IUUC-Olu-087670	Ostreococcus lucimarinus	53.62	9.00e-20	87.00
IUUC-Pno-094884	Phaeosphaeria nodorum	42.59	3.00e-21	92.40
IUUC-Pgr-103683	Puccinia graminis	40.00	7.00e-19	84.70
IUUC-Smo-109229	Selaginella moellendorffii	64.22	3.00e-36	142.00
IUUC-Tre-121926	Trichoderma reesei	42.31	1.00e-20	90.50
IUUC-Tur-126333	Triticum urartu	69.60	3.00e-41	159.00
IUUC-Tme-126902	Tuber melanosporum	46.36	1.00e-21	93.60
IUUC-Yli-134507	Yarrowia lipolytica	50.00	6.00e-12	60.80

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence